{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T00:04:22Z","timestamp":1758413062689,"version":"3.44.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100013183","name":"Swine Innovation Porc","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013183","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003069","name":"Instituto Polit\u00e9cnico Nacional","doi-asserted-by":"publisher","award":["20110124","20120122"],"award-info":[{"award-number":["20110124","20120122"]}],"id":[{"id":"10.13039\/501100003069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.lfs.2018.11.017","type":"journal-article","created":{"date-parts":[[2018,11,8]],"date-time":"2018-11-08T02:04:03Z","timestamp":1541642643000},"page":"22-28","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["(Pro)renin\/renin receptor expression during normal and preeclamptic pregnancy in rats"],"prefix":"10.1016","volume":"216","author":[{"given":"M.A.","family":"Avila-Ram\u00edrez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.L.","family":"Esteban-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"L\u00f3pez-Moctezuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Anguiano-Robledo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.E.","family":"Hern\u00e1ndez-Campos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8089-9794","authenticated-orcid":false,"given":"P.","family":"L\u00f3pez-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.lfs.2018.11.017_cf1105","first-page":"1","article-title":"Protein restriction to pregnant rats increases the plasma levels of angiotensin II and expression of angiotensin II receptors in uterine arteries","volume":"86","author":"Gao","year":"2011","journal-title":"Biol. Reprod."},{"issue":"12 Suppl","key":"10.1016\/j.lfs.2018.11.017_bb0010","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/00006254-199412011-00001","article-title":"Maternal cardiovascular hemodynamic adaptation to pregnancy","volume":"49","author":"Duvekot","year":"1994","journal-title":"Obstet. Gynecol. Surv."},{"issue":"6 Pt 2","key":"10.1016\/j.lfs.2018.11.017_bb0015","first-page":"H1911","article-title":"Systemic hemodynamics and oxygen transport during pregnancy in chronically instrumented, conscious rats","volume":"263","author":"Gilson","year":"1992","journal-title":"Am. J. Phys."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.017_bb0020","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1080\/10641950701252827","article-title":"Renal angiotensin-II receptors expression changes in a model of preeclampsia","volume":"26","author":"Anguiano-Robledo","year":"2007","journal-title":"Hypertens. Pregnancy"},{"issue":"8","key":"10.1016\/j.lfs.2018.11.017_bb0025","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1038\/ki.2009.284","article-title":"The biology of preeclampsia","volume":"76","author":"Kanasaki","year":"2009","journal-title":"Kidney Int."},{"issue":"8","key":"10.1016\/j.lfs.2018.11.017_bb0030","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1042\/CS20130455","article-title":"The renin-angiotensin-aldosterone system in pre-eclampsia: the delicate balance between good and bad","volume":"126","author":"Verdonk","year":"2014","journal-title":"Clin. Sci. (Lond.)"},{"issue":"6","key":"10.1016\/j.lfs.2018.11.017_bb0035","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.semnephrol.2004.07.011","article-title":"Animal models of preeclampsia","volume":"24","author":"Podjarny","year":"2004","journal-title":"Semin. Nephrol."},{"issue":"11","key":"10.1016\/j.lfs.2018.11.017_bb0040","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1172\/JCI0214276","article-title":"Pivotal role of the renin\/prorenin receptor in angiotensin II production and cellular responses to renin","volume":"109","author":"Nguyen","year":"2002","journal-title":"J. Clin. Invest."},{"issue":"5","key":"10.1016\/j.lfs.2018.11.017_bb0045","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1097\/FJC.0b013e3181f21576","article-title":"Cardiovascular and renal pathologic implications of prorenin, renin, and the (pro)renin receptor: promising young players from the old renin-angiotensin-aldosterone system","volume":"56","author":"Balakumar","year":"2010","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"5","key":"10.1016\/j.lfs.2018.11.017_bb0050","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1161\/HYPERTENSIONAHA.108.120279","article-title":"Prorenin, renin, and their receptor: moving targets","volume":"55","author":"Reudelhuber","year":"2010","journal-title":"Hypertension"},{"issue":"7","key":"10.1016\/j.lfs.2018.11.017_bb0055","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1161\/CIRCRESAHA.110.226977","article-title":"Involvement of the brain (pro)renin receptor in cardiovascular homeostasis","volume":"107","author":"Shan","year":"2010","journal-title":"Circ. Res."},{"issue":"6","key":"10.1016\/j.lfs.2018.11.017_bb0060","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1161\/HYPERTENSIONAHA.111.190108","article-title":"Brain-targeted (pro)renin receptor knockdown attenuates angiotensin II-dependent hypertension","volume":"59","author":"Li","year":"2012","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.lfs.2018.11.017_bb0065","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/hr.2009.206","article-title":"Signal transduction of the (pro)renin receptor as a novel therapeutic target for preventing end-organ damage","volume":"33","author":"Funke-Kaiser","year":"2010","journal-title":"Hypertens. Res."},{"issue":"4","key":"10.1016\/j.lfs.2018.11.017_bb0070","doi-asserted-by":"crossref","first-page":"795","DOI":"10.3892\/ijmm.2014.1624","article-title":"The (pro)renin receptor mediates constitutive PLZF-independent pro-proliferative effects which are inhibited by bafilomycin but not genistein","volume":"33","author":"Kirsch","year":"2014","journal-title":"Int. J. Mol. Med."},{"issue":"3","key":"10.1016\/j.lfs.2018.11.017_bb0075","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1177\/1470320310376554","article-title":"Molecular evidence of a (pro)renin\/(pro)renin receptor system in human intrauterine tissues in pregnancy and its association with PGHS-2","volume":"12","author":"Pringle","year":"2011","journal-title":"J. Renin-Angiotensin-Aldosterone Syst."},{"issue":"6","key":"10.1016\/j.lfs.2018.11.017_bb0080","doi-asserted-by":"crossref","first-page":"F1125","DOI":"10.1152\/ajprenal.00129.2016","article-title":"The enigma of continual plasma volume expansion in pregnancy: critical role of the renin-angiotensin-aldosterone system","volume":"311","author":"West","year":"2016","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.017_bb0085","first-page":"93","article-title":"Simplified technique to produce toxemia in the rat: considerations on cause of toxemia","volume":"1","author":"Abitbol","year":"1982","journal-title":"Clin. Exp. Hypertens. B"},{"issue":"1","key":"10.1016\/j.lfs.2018.11.017_bb0090","doi-asserted-by":"crossref","first-page":"H1","DOI":"10.1152\/ajpheart.00117.2012","article-title":"A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) model","volume":"303","author":"Li","year":"2012","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.017_bb0095","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ejogrb.2013.01.008","article-title":"Effect of morphine on the reduced uteroplacental perfusion model of pre-eclampsia in rats","volume":"168","author":"Javadian","year":"2013","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"1\u20133","key":"10.1016\/j.lfs.2018.11.017_bb0100","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ejphar.2008.12.050","article-title":"Inhibition of renin\/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release","volume":"606","author":"He","year":"2009","journal-title":"Eur. J. Pharmacol."},{"issue":"10","key":"10.1016\/j.lfs.2018.11.017_bb0105","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/S0006-2952(98)00021-5","article-title":"Regulation of cyclo-oxygenase gene expression in rat smooth muscle cells by catalase","volume":"55","author":"Chen","year":"1998","journal-title":"Biochem. Pharmacol."},{"issue":"7","key":"10.1016\/j.lfs.2018.11.017_bb0110","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/S1701-2163(15)30545-4","article-title":"Gestational hypertension and preeclampsia: are they the same disease?","volume":"36","author":"Melamed","year":"2014","journal-title":"J. Obstet. Gynaecol. Can."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.017_bb0115","doi-asserted-by":"crossref","first-page":"e89233","DOI":"10.1371\/journal.pone.0089233","article-title":"High glucose induces podocyte injury via enhanced (pro)renin receptor-Wnt-beta-catenin-snail signaling pathway","volume":"9","author":"Li","year":"2014","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.lfs.2018.11.017_bb0120","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1113\/expphysiol.2007.040550","article-title":"Renal (pro)renin receptor upregulation in diabetic rats through enhanced angiotensin AT1 receptor and NADPH oxidase activity","volume":"93","author":"Siragy","year":"2008","journal-title":"Exp. Physiol."},{"issue":"12","key":"10.1016\/j.lfs.2018.11.017_bb0125","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.1016\/j.peptides.2009.09.015","article-title":"Gene expression of (pro)renin receptor is upregulated in hearts and kidneys of rats with congestive heart failure","volume":"30","author":"Hirose","year":"2009","journal-title":"Peptides"},{"issue":"6","key":"10.1016\/j.lfs.2018.11.017_bb0130","first-page":"978","article-title":"Maternal central hemodynamics in hypertensive disorders of pregnancy","volume":"94","author":"Bosio","year":"1999","journal-title":"Obstet. Gynecol."},{"issue":"3","key":"10.1016\/j.lfs.2018.11.017_bb0135","doi-asserted-by":"crossref","first-page":"73","DOI":"10.2302\/kjm.61.73","article-title":"Pro)renin receptor and vacuolar H(+)-ATPase","volume":"61","author":"Ichihara","year":"2012","journal-title":"Keio J. Med."},{"issue":"11","key":"10.1016\/j.lfs.2018.11.017_bb0140","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1172\/JCI107462","article-title":"A study of angiotensin II pressor response throughout primigravid pregnancy","volume":"52","author":"Gant","year":"1973","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.lfs.2018.11.017_bb0145","doi-asserted-by":"crossref","first-page":"E810","DOI":"10.1152\/ajpendo.90264.2008","article-title":"Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells","volume":"295","author":"Zhang","year":"2008","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.017_bb0150","first-page":"H139","article-title":"The prorenin receptor in the cardiovascular system and beyond","volume":"314","author":"Hennrikus","year":"2018","journal-title":"Am. J. Phys. Heart Circ. Phys."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320518307197?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320518307197?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T20:16:27Z","timestamp":1758399387000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320518307197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":30,"alternative-id":["S0024320518307197"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2018.11.017","relation":{},"ISSN":["0024-3205"],"issn-type":[{"type":"print","value":"0024-3205"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"(Pro)renin\/renin receptor expression during normal and preeclamptic pregnancy in rats","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2018.11.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}