{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T11:42:43Z","timestamp":1771501363326,"version":"3.50.1"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.lfs.2018.11.031","type":"journal-article","created":{"date-parts":[[2018,11,16]],"date-time":"2018-11-16T04:11:25Z","timestamp":1542341485000},"page":"207-214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"special_numbering":"C","title":["Modulation of inducible nitric oxide synthase pathway by eugenol and telmisartan in carbon tetrachloride-induced liver injury in rats"],"prefix":"10.1016","volume":"216","author":[{"given":"Moustafa","family":"Fathy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esraa M.M.A.","family":"Khalifa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael Atef","family":"Fawzy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0088498","article-title":"Protection effect of kallistatin on carbon tetrachloride-induced liver fibrosis in rats via antioxidative stress","volume":"9","author":"Huang","year":"2014","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.lfs.2018.11.031_bb0010","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1172\/JCI66028","article-title":"Evolving therapies for liver fibrosis","volume":"123","author":"Schuppan","year":"2013","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0015","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/713611034","article-title":"Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model","volume":"33","author":"Weber","year":"2003","journal-title":"Crit. Rev. Toxicol."},{"issue":"11","key":"10.1016\/j.lfs.2018.11.031_bb0020","doi-asserted-by":"crossref","first-page":"25942","DOI":"10.3390\/ijms161125942","article-title":"The role of oxidative stress and antioxidants in liver diseases","volume":"16","author":"Li","year":"2015","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0025","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s11010-015-2572-2","article-title":"Experimental evidence for the therapeutic potential of tempol in the treatment of acute liver injury","volume":"411","author":"Abouzied","year":"2016","journal-title":"Mol. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0030","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1600-0676.1998.tb00120.x","article-title":"Signal transduction in hepatic stellate cells","volume":"18","author":"Pinzani","year":"1998","journal-title":"Liver"},{"issue":"5","key":"10.1016\/j.lfs.2018.11.031_bb0035","doi-asserted-by":"crossref","first-page":"G1069","DOI":"10.1152\/ajpgi.1999.276.5.G1069","article-title":"IV. Determinants of nitric oxide protection and toxicity in liver","volume":"276","author":"Li","year":"1999","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"8","key":"10.1016\/j.lfs.2018.11.031_bb0040","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/S1567-5769(01)00086-8","article-title":"Nitric oxide in immunity and inflammation","volume":"1","author":"Coleman","year":"2001","journal-title":"Int. Immunopharmacol."},{"issue":"5","key":"10.1016\/j.lfs.2018.11.031_bb0045","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s12199-013-0336-8","article-title":"In vivo modulation of iNOS pathway in hepatocellular carcinoma by Nigella sativa","volume":"18","author":"Fathy","year":"2013","journal-title":"Environ. Health Prev. Med."},{"issue":"4","key":"10.1016\/j.lfs.2018.11.031_bb0050","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.cld.2008.07.005","article-title":"Oxidative and nitrosative stress and fibrogenic response","volume":"12","author":"Urtasun","year":"2008","journal-title":"Clin. Liver Dis."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0055","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ijid.2007.03.010","article-title":"Inducible nitric oxide synthase and histopathological correlation in chronic viral hepatitis","volume":"12","author":"Atik","year":"2008","journal-title":"Int. J. Infect. Dis."},{"issue":"Suppl. 1","key":"10.1016\/j.lfs.2018.11.031_bb0060","first-page":"S73","article-title":"Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis","volume":"22","author":"Kisseleva","year":"2007","journal-title":"J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.lfs.2018.11.031_bb0065","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1155\/2014\/696383","article-title":"Diethylcarbamazine reduces chronic inflammation and fibrosis in carbon tetrachloride- (CCl4-) induced liver injury in mice","volume":"2014","author":"Rocha","year":"2014","journal-title":"Mediat. Inflamm."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0070","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3906\/sag-1701-86","article-title":"In vivo attenuation of angiogenesis in hepatocellular carcinoma by Nigella sativa","volume":"48","author":"Fathy","year":"2018","journal-title":"Turk. J. Med. Sci."},{"issue":"3","key":"10.1016\/j.lfs.2018.11.031_bb0075","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s11596-011-0374-7","article-title":"Telmisartan protects against insulin resistance by attenuating inflammatory response in rats","volume":"31","author":"Xu","year":"2011","journal-title":"J. Huazhong Univ. Sci. Technolog. Med. Sci."},{"issue":"3","key":"10.1016\/j.lfs.2018.11.031_bb0080","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.tox.2009.12.018","article-title":"Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats","volume":"268","author":"Yogalakshmi","year":"2010","journal-title":"Toxicology"},{"key":"10.1016\/j.lfs.2018.11.031_bb0085","series-title":"Protective Effect of Eugenol against Alcohol-Induced Biochemical Changes in Rats","author":"Anbu","year":"2011"},{"issue":"8","key":"10.1016\/j.lfs.2018.11.031_bb0090","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1248\/bpb.b14-00281","article-title":"Eugenol ameliorates hepatic steatosis and fibrosis by down-regulating SREBP1 gene expression via AMPK-mTOR-p70S6K signaling pathway","volume":"37","author":"Jo","year":"2014","journal-title":"Biol. Pharm. Bull."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0095","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s11010-013-1824-2","article-title":"Ameliorating effect of eugenol on hyperglycemia by attenuating the key enzymes of glucose metabolism in streptozotocin-induced diabetic rats","volume":"385","author":"Srinivasan","year":"2014","journal-title":"Mol. Cell. Biochem."},{"issue":"4","key":"10.1016\/j.lfs.2018.11.031_bb0100","doi-asserted-by":"crossref","first-page":"288","DOI":"10.15430\/JCP.2014.19.4.288","article-title":"Eugenol-rich fraction of Syzygium aromaticum (clove) reverses biochemical and histopathological changes in liver cirrhosis and inhibits hepatic cell proliferation","volume":"19","author":"Ali","year":"2014","journal-title":"J. Cancer Prev."},{"key":"10.1016\/j.lfs.2018.11.031_bb0105","doi-asserted-by":"crossref","first-page":"989163","DOI":"10.1155\/2010\/989163","article-title":"Effect of honey and eugenol on Ehrlich ascites and solid carcinoma","volume":"2010","author":"Jaganathan","year":"2010","journal-title":"J Biomed Biotechnol"},{"issue":"3","key":"10.1016\/j.lfs.2018.11.031_bb0110","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.tox.2012.06.015","article-title":"Telmisartan treatment attenuates arsenic-induced hepatotoxicity in mice","volume":"300","author":"Fouad","year":"2012","journal-title":"Toxicology"},{"issue":"7","key":"10.1016\/j.lfs.2018.11.031_bb0115","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1111\/j.1478-3231.2009.02006.x","article-title":"Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue","volume":"29","author":"Kudo","year":"2009","journal-title":"Liver Int."},{"issue":"6","key":"10.1016\/j.lfs.2018.11.031_bb0120","doi-asserted-by":"crossref","first-page":"698","DOI":"10.3390\/molecules21060698","article-title":"Metabolic profile changes of CCl4-liver fibrosis and inhibitory effects of jiaqi ganxian granule","volume":"21","author":"Wang","year":"2016","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0125","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1186\/s12906-016-1238-2","article-title":"Hepatoprotective activity of ethanolic extract of Salix subserrata against CCl4-induced chronic hepatotoxicity in rats","volume":"16","author":"Wahid","year":"2016","journal-title":"BMC Complement. Altern. Med."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0130","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S0021-9258(18)57021-6","article-title":"Determination of serum proteins by means of the biuret reaction","volume":"177","author":"Gornall","year":"1949","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0135","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/ajcp\/28.1.56","article-title":"A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases","volume":"28","author":"Reitman","year":"1957","journal-title":"Am. J. Clin. Pathol."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0140","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/abio.2002.5676","article-title":"Spectrophotometric determination of serum nitrite and nitrate by copper\u2013cadmium alloy","volume":"306","author":"Sastry","year":"2002","journal-title":"Anal. Biochem."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0145","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal. Biochem."},{"issue":"8","key":"10.1016\/j.lfs.2018.11.031_bb0150","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3390\/s30800276","article-title":"Measurement of nitric oxide production in biological systems by using griess reaction assay","volume":"3","author":"Sun","year":"2003","journal-title":"Sensors"},{"key":"10.1016\/j.lfs.2018.11.031_bb0155","first-page":"882","article-title":"Improved method for the determination of blood glutathione","volume":"61","author":"Beutler","year":"1963","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.lfs.2018.11.031_bb0160","series-title":"Theory and Practice of Histological Techniques","author":"Bancroft","year":"2008"},{"issue":"3","key":"10.1016\/j.lfs.2018.11.031_bb0165","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.cbi.2011.07.001","article-title":"Molecular pathogenesis of hepatic fibrosis and current therapeutic approaches","volume":"193","author":"Mormone","year":"2011","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.lfs.2018.11.031_bb0170","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nrgastro.2010.213","article-title":"NF-\u03baB in the liver\u2014linking injury, fibrosis and hepatocellular carcinoma","volume":"8","author":"Luedde","year":"2011","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0175","first-page":"69","article-title":"Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell","volume":"8","author":"Gabele","year":"2003","journal-title":"Front. Biosci."},{"issue":"23","key":"10.1016\/j.lfs.2018.11.031_bb0180","doi-asserted-by":"crossref","first-page":"7312","DOI":"10.3748\/wjg.v20.i23.7312","article-title":"Pathogenesis of liver cirrhosis","volume":"20","author":"Zhou","year":"2014","journal-title":"World J Gastroenterol: WJG"},{"key":"10.1016\/j.lfs.2018.11.031_bb0185","first-page":"361","article-title":"Molecular pathogenesis of liver fibrosis","volume":"120","author":"Brenner","year":"2009","journal-title":"Trans. Am. Clin. Climatol. Assoc."},{"issue":"6","key":"10.1016\/j.lfs.2018.11.031_bb0190","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1177\/1756283X11413002","article-title":"Current status of novel antifibrotic therapies in patients with chronic liver disease","volume":"4","author":"Cohen-Naftaly","year":"2011","journal-title":"Ther. Adv. Gastroenterol."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0195","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1248\/bpb.35.171","article-title":"The molecular mechanisms of the hepatoprotective effect of gomisin a against oxidative stress and inflammatory response in rats with carbon tetrachloride-induced acute liver injury","volume":"35","author":"Teraoka","year":"2012","journal-title":"Biol. Pharm. Bull."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0200","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.jep.2011.11.033","article-title":"Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation","volume":"139","author":"Xiao","year":"2012","journal-title":"J. Ethnopharmacol."},{"issue":"22","key":"10.1016\/j.lfs.2018.11.031_bb0205","first-page":"1880","article-title":"Cystic degeneration in liver injury induced by CCl4 in SD rats","volume":"31","author":"Xu","year":"2006","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0210","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.taap.2011.02.004","article-title":"Comparison of imatinib, nilotinib and silymarin in the treatment of carbon tetrachloride-induced hepatic oxidative stress, injury and fibrosis","volume":"252","author":"Shaker","year":"2011","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"3","key":"10.1016\/j.lfs.2018.11.031_bb0215","first-page":"5","article-title":"Hepatoprotective effect of aqueous extract of Melothria perpusilla against carbon tetrachloride induced liver injury in albino rats","volume":"5","author":"Yengkhom","year":"2017"},{"issue":"4","key":"10.1016\/j.lfs.2018.11.031_bb0220","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s00534-002-0824-5","article-title":"Catalase, superoxide dismutase, and glutathione peroxidase activities in various rat tissues after carbon tetrachloride intoxication","volume":"10","author":"Szymonik-Lesiuk","year":"2003","journal-title":"J. Hepato-Biliary-Pancreat. Surg."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0225","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1055\/s-2007-1007110","article-title":"Cytokines in alcoholic liver disease","volume":"19","author":"McClain","year":"1999","journal-title":"Semin. Liver Dis."},{"issue":"11","key":"10.1016\/j.lfs.2018.11.031_bb0230","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/j.bcp.2006.04.011","article-title":"NF-\u03baB activation by reactive oxygen species: fifteen years later","volume":"72","author":"Gloire","year":"2006","journal-title":"Biochem. Pharmacol."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0235","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jss.2009.09.019","article-title":"Nitric oxide and redox regulation in the liver: part I. General considerations and redox biology in hepatitis","volume":"162","author":"Diesen","year":"2010","journal-title":"J. Surg. Res."},{"issue":"4","key":"10.1016\/j.lfs.2018.11.031_bb0240","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3350\/cmh.2015.21.4.319","article-title":"Nitric oxide in liver fibrosis: the role of inducible nitric oxide synthase","volume":"21","author":"Iwakiri","year":"2015","journal-title":"Clin. Mol. Hepatol."},{"key":"10.1016\/j.lfs.2018.11.031_bb0245","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.fct.2012.10.059","article-title":"Puerarin mediates hepatoprotection against CCl4-induced hepatic fibrosis rats through attenuation of inflammation response and amelioration of metabolic function","volume":"52","author":"Li","year":"2013","journal-title":"Food Chem. Toxicol."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0250","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3181\/00379727-210-43927AA","article-title":"Nitric oxide: a novel mediator of inflammation","volume":"210","author":"Clancy","year":"1995","journal-title":"Proc. Soc. Exp. Biol. Med."},{"issue":"52","key":"10.1016\/j.lfs.2018.11.031_bb0255","doi-asserted-by":"crossref","first-page":"19777","DOI":"10.1073\/pnas.0605907103","article-title":"Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking","volume":"103","author":"Iwakiri","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"5","key":"10.1016\/j.lfs.2018.11.031_bb0260","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1006\/niox.1997.0143","article-title":"DNA damage induced by peroxynitrite: subsequent biological effects","volume":"1","author":"Szab\u00f3","year":"1997","journal-title":"Nitric Oxide"},{"issue":"11","key":"10.1016\/j.lfs.2018.11.031_bb0265","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1016\/0006-2952(92)90318-D","article-title":"Inhibitory effect of eugenol on non-enzymatic lipid peroxidation in rat liver mitochondria","volume":"43","author":"Nagababu","year":"1992","journal-title":"Biochem. Pharmacol."},{"issue":"1","key":"10.1016\/j.lfs.2018.11.031_bb0270","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.mrgentox.2009.05.016","article-title":"Investigation of anti-oxidative, cytotoxic, DNA-damaging and DNA-protective effects of plant volatiles eugenol and borneol in human-derived HepG2, Caco-2 and VH10 cell lines","volume":"677","author":"Slame\u0148ov\u00e1","year":"2009","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen."},{"issue":"5","key":"10.1016\/j.lfs.2018.11.031_bb0275","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/0006-2952(88)90164-5","article-title":"Enhancement of UDP-glucuronyltransferase, UDP-glucose dehydrogenase, and glutathione S-transferase activities in rat liver by dietary administration of eugenol","volume":"37","author":"Yokota","year":"1988","journal-title":"Biochem. Pharmacol."},{"issue":"3","key":"10.1016\/j.lfs.2018.11.031_bb0280","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0024-3205(03)00288-1","article-title":"Eugenol suppresses cyclooxygenase-2 expression in lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells","volume":"73","author":"Kim","year":"2003","journal-title":"Life Sci."},{"issue":"2","key":"10.1016\/j.lfs.2018.11.031_bb0285","doi-asserted-by":"crossref","first-page":"69","DOI":"10.2220\/biomedres.27.69","article-title":"Inhibitory action of eugenol compounds on the production of nitric oxide in RAW264.7 macrophages","volume":"27","author":"Li","year":"2006","journal-title":"Biomed. Res."},{"issue":"5","key":"10.1016\/j.lfs.2018.11.031_bb0290","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1161\/01.HYP.0000123072.34629.57","article-title":"Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPAR\u03b3\u2013modulating activity","volume":"43","author":"Benson","year":"2004","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.lfs.2018.11.031_bb0295","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3109\/02713681003664923","article-title":"Reduction of inducible nitric oxide synthase via angiotensin receptor blocker prevents the oxidative retinal damage in diabetic hypertensive rats","volume":"35","author":"Silva","year":"2010","journal-title":"Curr. Eye Res."},{"issue":"5","key":"10.1016\/j.lfs.2018.11.031_bb0300","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1002\/hep.20665","article-title":"Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct\u2013ligated rats","volume":"41","author":"Bataller","year":"2005","journal-title":"Hepatology"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320518307446?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320518307446?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T20:17:48Z","timestamp":1758399468000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320518307446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":60,"alternative-id":["S0024320518307446"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2018.11.031","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Modulation of inducible nitric oxide synthase pathway by eugenol and telmisartan in carbon tetrachloride-induced liver injury in rats","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2018.11.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}