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Heart J. 36 (2015) 2297\u20132309. doi:https:\/\/doi.org\/10.1093\/eurheartj\/ehv259.","DOI":"10.1093\/eurheartj\/ehv259"},{"key":"10.1016\/j.lfs.2019.05.012_bb0785","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.biotechadv.2013.12.010","article-title":"Hydrogel based injectable scaffolds for cardiac tissue regeneration","volume":"32","author":"Radhakrishnan","year":"2014","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.lfs.2019.05.012_bb0790","article-title":"H-Sensitive and Thermosensitive Hydrogels as Stem-Cell Carriers for Cardiac Therapy","volume":"8","author":"Li","year":"2016","journal-title":"ACS Appl. Mater. 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Commun."},{"key":"10.1016\/j.lfs.2019.05.012_bb0825","doi-asserted-by":"crossref","DOI":"10.1038\/srep32068","article-title":"Anisotropic engineered heart tissue made from laser-cut decellularized myocardium","volume":"6","author":"Schwan","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2019.05.012_bb0830","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.biomaterials.2017.02.011","article-title":"Crossing kingdoms: using decellularized plants as perfusable tissue engineering scaffolds","volume":"125","author":"Gershlak","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.lfs.2019.05.012_bb0835","series-title":"Tissue Engineering with Decellularized Tissues","author":"Badylak","year":"2013"},{"key":"10.1016\/j.lfs.2019.05.012_bb0840","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.biomaterials.2016.07.038","article-title":"Direct 3D bioprinting of perfusable vascular constructs using a blend bioink","volume":"106","author":"Jia","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.lfs.2019.05.012_bb0845","article-title":"A. Atala, 3D bioprinted functional and contractile cardiac tissue constructs","author":"Wang","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.lfs.2019.05.012_bb0850","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.biomaterials.2017.01.042","article-title":"Direct 3D bioprinting of prevascularized tissue constructs with complex microarchitecture","volume":"124","author":"Zhu","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.lfs.2019.05.012_bb0855","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.actbio.2017.05.044","article-title":"Combinatorial screening of 3D biomaterial properties that promote myofibrogenesis for mesenchymal stromal cell-based heart valve tissue engineering","volume":"58","author":"Usprech","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.lfs.2019.05.012_bb0860","first-page":"365","article-title":"Alignment of cells and extracellular matrix within tissue-engineered substitutes","author":"Bourget","year":"2013","journal-title":"Adv. Biomater. Sci. Biomed. Appl. Ref."},{"key":"10.1016\/j.lfs.2019.05.012_bb0865","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1039\/C5LC01356A","article-title":"Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues","volume":"16","author":"Marsano","year":"2016","journal-title":"Lab Chip"},{"key":"10.1016\/j.lfs.2019.05.012_bb0870","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.biomaterials.2016.09.003","article-title":"Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip","volume":"110","author":"Zhang","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.lfs.2019.05.012_bb0875","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/7\/3\/035007","article-title":"Multiphoton crosslinking for biocompatible 3D printing of type I collagen","volume":"7","author":"Bell","year":"2015","journal-title":"Biofabrication"},{"key":"10.1016\/j.lfs.2019.05.012_bb0880","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.actbio.2016.11.009","article-title":"I-wire heart-on-a-Chip I: three-dimensional cardiac tissue constructs for physiology and pharmacology","volume":"48","author":"Sidorov","year":"2017","journal-title":"Acta Biomater."},{"key":"10.1016\/j.lfs.2019.05.012_bb0885","first-page":"1","article-title":"Title: 3D printed vascular networks direct therapeutic angiogenesis in ischemia","volume":"0083","author":"Mirabella","year":"2017","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.lfs.2019.05.012_bb0890","doi-asserted-by":"crossref","unstructured":"A. Tijore, S.A. Irvine, U. Sarig, P. Mhaisalkar, V. Baisane, S.S. Venkatraman, Contact guidance for cardiac tissue engineering using 3D bioprinted gelatin patterned hydrogel., Biofabrication. 10 (2017) 025003. doi:https:\/\/doi.org\/10.1088\/1758-5090\/aaa15d.","DOI":"10.1088\/1758-5090\/aaa15d"},{"key":"10.1016\/j.lfs.2019.05.012_bb0895","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1177\/2472630317705610","article-title":"Heart-on-a-Chip: an investigation of the influence of static and perfusion conditions on cardiac (H9C2) cell proliferation, morphology, and alignment","volume":"22","author":"Kobuszewska","year":"2017","journal-title":"SLAS Technol"},{"key":"10.1016\/j.lfs.2019.05.012_bb0900","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/nmat4782","article-title":"Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing","volume":"16","author":"Lind","year":"2017","journal-title":"Nat. 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