{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T14:30:40Z","timestamp":1792593040025,"version":"4.5.0"},"reference-count":126,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.lfs.2020.117447","type":"journal-article","created":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T07:30:57Z","timestamp":1582097457000},"page":"117447","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":161,"special_numbering":"C","title":["Free and hydrogel encapsulated exosome-based therapies in regenerative medicine"],"prefix":"10.1016","volume":"249","author":[{"given":"Ali","family":"Akbari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nassrollah","family":"Jabbari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roholah","family":"Sharifi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahdi","family":"Ahmadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Vahhabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyyed Javad","family":"Seyedzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Nawaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u0142awomir","family":"Szafert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monireh","family":"Mahmoodi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esmaiel","family":"Jabbari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahim","family":"Asghari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jafar","family":"Rezaie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2020.117447_bb0005","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3390\/pharmaceutics10040218","article-title":"Exosomes and exosome-inspired vesicles for targeted drug delivery","volume":"10","author":"Antimisiaris","year":"2018","journal-title":"Pharmaceutics."},{"key":"10.1016\/j.lfs.2020.117447_bb0010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0189428","article-title":"Chondrocytes and stem cells in 3D-bioprinted structures create human cartilage in vivo","volume":"12","author":"Apelgren","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2020.117447_bb0015","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.scr.2013.01.002","article-title":"Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K\/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia\/reperfusion injury","volume":"10","author":"Arslan","year":"2013","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0020","doi-asserted-by":"crossref","DOI":"10.1038\/srep10721","article-title":"Biodistribution and function of extracellular miRNA-155 in mice","volume":"5","author":"Bala","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2020.117447_bb0025","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00109-013-1110-5","article-title":"Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model","volume":"92","author":"Bian","year":"2014","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0030","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1093\/ndt\/gfs168","article-title":"Therapeutic potential of mesenchymal stem cell-derived microvesicles","volume":"27","author":"Biancone","year":"2012","journal-title":"Nephrology Dialysis Transplantation."},{"key":"10.1016\/j.lfs.2020.117447_bb0035","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1681\/ASN.2008070798","article-title":"Mesenchymal stem cell-derived microvesicles protect against acute tubular injury","volume":"20","author":"Bruno","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.lfs.2020.117447_bb0040","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1089\/ten.tea.2017.0069","article-title":"Renal regenerative potential of different extracellular vesicle populations derived from bone marrow mesenchymal stromal cells","volume":"23","author":"Bruno","year":"2017","journal-title":"Tissue Eng. A"},{"key":"10.1016\/j.lfs.2020.117447_bb0045","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jaci.2013.04.048","article-title":"Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity","volume":"132","author":"Bryniarski","year":"2013","journal-title":"Journal of Allergy and Clinical Immunology"},{"key":"10.1016\/j.lfs.2020.117447_bb0050","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3389\/fcell.2016.00083","article-title":"Stem cell-derived extracellular vesicles and immune-modulation","volume":"4","author":"Burrello","year":"2016","journal-title":"Frontiers in Cell and Developmental Biology."},{"key":"10.1016\/j.lfs.2020.117447_bb0055","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/nar\/gkp857","article-title":"Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs","volume":"38","author":"Chen","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0060","article-title":"Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury","volume":"9","author":"Choi","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2020.117447_bb0065","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.tcb.2008.11.003","article-title":"Shedding microvesicles: artefacts no more","volume":"19","author":"Cocucci","year":"2009","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.lfs.2020.117447_bb0070","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1126\/science.1064829","article-title":"Taking cell-matrix adhesions to the third dimension","volume":"294","author":"Cukierman","year":"2001","journal-title":"Science."},{"key":"10.1016\/j.lfs.2020.117447_bb0075","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1007\/s00395-005-0552-5","article-title":"Adult bone marrow\u2013derived cells: regenerative potential, plasticity, and tissue commitment","volume":"100","author":"Dawn","year":"2005","journal-title":"Basic Res. Cardiol."},{"key":"10.1016\/j.lfs.2020.117447_bb0080","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.5966\/sctm.2015-0078","article-title":"Extracellular vesicles improve post-stroke neuroregeneration and prevent postischemic immunosuppression","volume":"4","author":"Doeppner","year":"2015","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0085","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.bbi.2016.11.011","article-title":"Mesenchymal stem cell-derived extracellular vesicles ameliorate inflammation-induced preterm brain injury","volume":"60","author":"Drommelschmidt","year":"2017","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.lfs.2020.117447_bb0090","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/7\/4\/044104","article-title":"3D bioprinting of BMSC-laden methacrylamide gelatin scaffolds with CBD-BMP2-collagen microfibers","volume":"7","author":"Du","year":"2015","journal-title":"Biofabrication."},{"key":"10.1016\/j.lfs.2020.117447_bb0095","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1002\/adhm.201501033","article-title":"Bioprinting organotypic hydrogels with improved mesenchymal stem cell remodeling and mineralization properties for bone tissue engineering","volume":"5","author":"Duarte Campos","year":"2016","journal-title":"Advanced Healthcare Materials."},{"key":"10.1016\/j.lfs.2020.117447_bb0100","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.5966\/sctm.2015-0367","article-title":"Umbilical cord-derived mesenchymal stem cell-derived exosomal micrornas suppress myofibroblast differentiation by inhibiting the transforming growth factor-\u03b2\/SMAD2 pathway during wound healing","volume":"5","author":"Fang","year":"2016","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0105","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s40880-015-0051-5","article-title":"Stem cell-derived exosomes: roles in stromal remodeling, tumor progression, and cancer immunotherapy","volume":"34","author":"Fatima","year":"2015","journal-title":"Chinese Journal of Cancer."},{"key":"10.1016\/j.lfs.2020.117447_bb0110","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1089\/ten.tec.2016.0329","article-title":"Spheroid coculture of hematopoietic stem\/progenitor cells and monolayer expanded mesenchymal stem\/stromal cells in polydimethylsiloxane microwells modestly improves in vitro hematopoietic stem\/progenitor cell expansion","volume":"23","author":"Futrega","year":"2017","journal-title":"Tissue Engineering Part C: Methods."},{"key":"10.1016\/j.lfs.2020.117447_bb0115","doi-asserted-by":"crossref","first-page":"9218","DOI":"10.1016\/j.biomaterials.2011.08.071","article-title":"Patterning human stem cells and endothelial cells with laser printing for cardiac regeneration","volume":"32","author":"Gaebel","year":"2011","journal-title":"Biomaterials."},{"key":"10.1016\/j.lfs.2020.117447_bb0120","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1093\/ndt\/gfr015","article-title":"Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia\u2013reperfusion-induced acute and chronic kidney injury","volume":"26","author":"Gatti","year":"2011","journal-title":"Nephrology Dialysis Transplantation."},{"key":"10.1016\/j.lfs.2020.117447_bb0125","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.3390\/ijms15033640","article-title":"An overview of poly (lactic-co-glycolic) acid (PLGA)-based biomaterials for bone tissue engineering","volume":"15","author":"Gentile","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2020.117447_bb0130","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1096\/fj.05-5211com","article-title":"Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement","volume":"20","author":"Gnecchi","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.lfs.2020.117447_bb0135","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1158\/1541-7786.MCR-18-0891","article-title":"Internalization of exosomes through receptor-mediated endocytosis","volume":"17","author":"Gonda","year":"2019","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0140","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1038\/ncomms3123","article-title":"Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma","volume":"4","author":"Grapp","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.lfs.2020.117447_bb0145","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1007\/s00018-011-0689-3","article-title":"Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles","volume":"68","author":"Gy\u00f6rgy","year":"2011","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.lfs.2020.117447_bb0150","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/biot.201200200","article-title":"Development of 3D hydrogel culture systems with on-demand cell separation","volume":"8","author":"Hamilton","year":"2013","journal-title":"Biotechnol. J."},{"key":"10.1016\/j.lfs.2020.117447_bb0155","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.msec.2019.01.122","article-title":"Delivery of miR-675 by stem cell-derived exosomes encapsulated in silk fibroin hydrogel prevents aging-induced vascular dysfunction in mouse hindlimb","volume":"99","author":"Han","year":"2019","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.lfs.2020.117447_bb0160","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jconrel.2015.03.033","article-title":"Exosomes as drug delivery vehicles for Parkinson\u2019s disease therapy","volume":"207","author":"Haney","year":"2015","journal-title":"J. Control. Release"},{"key":"10.1016\/j.lfs.2020.117447_bb0165","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1083\/jcb.97.2.329","article-title":"Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes","volume":"97","author":"Harding","year":"1983","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.lfs.2020.117447_bb0170","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1440-1797.2012.01589.x","article-title":"Bone marrow stem cells-derived microvesicles protect against renal injury in the mouse remnant kidney model","volume":"17","author":"He","year":"2012","journal-title":"Nephrology."},{"key":"10.1016\/j.lfs.2020.117447_bb0175","doi-asserted-by":"crossref","first-page":"a016766","DOI":"10.1101\/cshperspect.a016766","article-title":"Molecular mechanisms of the membrane sculpting ESCRT pathway","volume":"5","author":"Henne","year":"2013","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.lfs.2020.117447_bb0180","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.celrep.2013.10.050","article-title":"Exosome secretion is enhanced by invadopodia and drives invasive behavior","volume":"5","author":"Hoshino","year":"2013","journal-title":"Cell Rep."},{"key":"10.1016\/j.lfs.2020.117447_bb0185","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.3892\/ijmm.2016.2712","article-title":"Three-dimensional co-culture of mesenchymal stromal cells and differentiated osteoblasts on human bio-derived bone scaffolds supports active multi-lineage hematopoiesis in vitro: functional implication of the biomimetic HSC niche","volume":"38","author":"Huang","year":"2016","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0190","doi-asserted-by":"crossref","first-page":"5319","DOI":"10.1039\/C4TB00775A","article-title":"Hydrogels for tissue engineering and regenerative medicine","volume":"2","author":"Hunt","year":"2014","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.lfs.2020.117447_bb0195","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s10529-010-0221-0","article-title":"Cell encapsulation using biopolymer gels for regenerative medicine","volume":"32","author":"Hunt","year":"2010","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.lfs.2020.117447_bb0200","doi-asserted-by":"crossref","first-page":"7698","DOI":"10.1021\/nn402232g","article-title":"Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors","volume":"7","author":"Jang","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.lfs.2020.117447_bb0205","doi-asserted-by":"crossref","first-page":"9412","DOI":"10.1016\/S0021-9258(18)48095-7","article-title":"Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)","volume":"262","author":"Johnstone","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2020.117447_bb0210","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0121534","article-title":"Microvesicles derived from human umbilical cord mesenchymal stem cells facilitate tubular epithelial cell dedifferentiation and growth via hepatocyte growth factor induction","volume":"10","author":"Ju","year":"2015","journal-title":"PloS One"},{"key":"10.1016\/j.lfs.2020.117447_bb0215","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/659890","article-title":"Exosomes secreted from CXCR4 overexpressing mesenchymal stem cells promote cardioprotection via Akt signaling pathway following myocardial infarction","volume":"2015","author":"Kang","year":"2015","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.lfs.2020.117447_bb0220","doi-asserted-by":"crossref","DOI":"10.1002\/aoc.4359","article-title":"POSS nanocrosslinked poly (ethylene glycol) hydrogel as hybrid material support for silver nanocatalyst","volume":"32","author":"Kazeminava","year":"2018","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.lfs.2020.117447_bb0225","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.biomaterials.2018.03.040","article-title":"3D cell printing of in vitro stabilized skin model and in vivo pre-vascularized skin patch using tissue-specific extracellular matrix bioink: a step towards advanced skin tissue engineering","volume":"168","author":"Kim","year":"2018","journal-title":"Biomaterials."},{"key":"10.1016\/j.lfs.2020.117447_bb0230","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jiec.2016.04.013","article-title":"Bi-compartmental 3D scaffolds for the co-culture of intervertebral disk cells and mesenchymal stem cells","volume":"38","author":"Kook","year":"2016","journal-title":"J. Ind. Eng. Chem."},{"key":"10.1016\/j.lfs.2020.117447_bb0235","doi-asserted-by":"crossref","first-page":"117","DOI":"10.3390\/nano8020117","article-title":"Promotion of vascular morphogenesis of endothelial cells co-cultured with human adipose-derived mesenchymal stem cells using polycaprolactone\/gelatin nanofibrous scaffolds","volume":"8","author":"Kook","year":"2018","journal-title":"Nanomaterials."},{"key":"10.1016\/j.lfs.2020.117447_bb0240","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1074\/jbc.M111.288662","article-title":"Competitive interactions of cancer cells and normal cells via secretory microRNAs","volume":"287","author":"Kosaka","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2020.117447_bb0245","doi-asserted-by":"crossref","first-page":"17442","DOI":"10.1074\/jbc.M110.107821","article-title":"Secretory mechanisms and intercellular transfer of microRNAs in living cells","volume":"285","author":"Kosaka","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2020.117447_bb0250","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ceb.2014.05.004","article-title":"Biogenesis and secretion of exosomes","volume":"29","author":"Kowal","year":"2014","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.lfs.2020.117447_bb0255","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.scr.2009.12.003","article-title":"Exosome secreted by MSC reduces myocardial ischemia\/reperfusion injury","volume":"4","author":"Lai","year":"2010","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0260","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/971907","article-title":"Proteolytic potential of the MSC exosome proteome: implications for an exosome-mediated delivery of therapeutic proteasome","volume":"2012","author":"Lai","year":"2012","journal-title":"International Journal of Proteomics."},{"key":"10.1016\/j.lfs.2020.117447_bb0265","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1161\/CIRCULATIONAHA.112.114173","article-title":"Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertens","author":"Lee","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2020.117447_bb0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mser.2017.07.001","article-title":"Spatially and temporally controlled hydrogels for tissue engineering","volume":"119","author":"Leijten","year":"2017","journal-title":"Mat Sci Eng R."},{"key":"10.1016\/j.lfs.2020.117447_bb0275","doi-asserted-by":"crossref","first-page":"8589","DOI":"10.1021\/acsami.7b00728","article-title":"Microfluidic encapsulation of human mesenchymal stem cells for articular cartilage tissue regeneration","volume":"9","author":"Li","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.lfs.2020.117447_bb0280","doi-asserted-by":"crossref","first-page":"6830","DOI":"10.1039\/C6TB01560C","article-title":"Fabrication of hydroxyapatite\/chitosan composite hydrogels loaded with exosomes derived from miR-126-3p overexpressed synovial mesenchymal stem cells for diabetic chronic wound healing","volume":"4","author":"Li","year":"2016","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.lfs.2020.117447_bb0285","doi-asserted-by":"crossref","first-page":"5240","DOI":"10.1021\/acsami.7b17620","article-title":"Tissue-engineered bone immobilized with human adipose stem cells-derived exosomes promotes bone regeneration","volume":"10","author":"Li","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.lfs.2020.117447_bb0290","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.ebiom.2016.04.030","article-title":"Exosome derived from human umbilical cord mesenchymal stem cell mediates MiR-181c attenuating burn-induced excessive inflammation","volume":"8","author":"Li","year":"2016","journal-title":"EBioMedicine."},{"key":"10.1016\/j.lfs.2020.117447_bb0295","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1242\/jcs.170373","article-title":"Exosomes secreted by mesenchymal stem cells promote endothelial cell angiogenesis by transferring miR-125a","volume":"129","author":"Liang","year":"2016","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.lfs.2020.117447_bb0300","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/aa71da","article-title":"Synthesis of cell composite alginate microfibers by microfluidics with the application potential of small diameter vascular grafts","volume":"9","author":"Liu","year":"2017","journal-title":"Biofabrication."},{"key":"10.1016\/j.lfs.2020.117447_bb0305","doi-asserted-by":"crossref","first-page":"4430","DOI":"10.1039\/C7NR00352H","article-title":"Integration of stem cell-derived exosomes with in situ hydrogel glue as a promising tissue patch for articular cartilage regeneration","volume":"9","author":"Liu","year":"2017","journal-title":"Nanoscale."},{"key":"10.1016\/j.lfs.2020.117447_bb0310","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41420-019-0159-5","article-title":"Exosomes from adipose-derived mesenchymal stem cells prevent cardiomyocyte apoptosis induced by oxidative stress","volume":"5","author":"Liu","year":"2019","journal-title":"Cell Death Discovery."},{"key":"10.1016\/j.lfs.2020.117447_bb0315","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1161\/CIRCRESAHA.116.310374","article-title":"Fabrication of synthetic mesenchymal stem cells for the treatment of acute myocardial infarction in mice","volume":"120","author":"Luo","year":"2017","journal-title":"Circ. Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0320","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1016\/j.jprot.2010.06.006","article-title":"Exosomes: extracellular organelles important in intercellular communication","volume":"73","author":"Mathivanan","year":"2010","journal-title":"J. Proteome"},{"key":"10.1016\/j.lfs.2020.117447_bb0325","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1111\/cas.13310","article-title":"Accelerated growth of B16 BL 6 tumor in mice through efficient uptake of their own exosomes by B16 BL 6 cells","volume":"108","author":"Matsumoto","year":"2017","journal-title":"Cancer Sci."},{"key":"10.1016\/j.lfs.2020.117447_bb0330","doi-asserted-by":"crossref","first-page":"9343","DOI":"10.1016\/j.actbio.2013.07.023","article-title":"Dental mesenchymal stem cells encapsulated in an alginate hydrogel co-delivery microencapsulation system for cartilage regeneration","volume":"9","author":"Moshaverinia","year":"2013","journal-title":"Acta Biomater."},{"key":"10.1016\/j.lfs.2020.117447_bb0335","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/1073140","article-title":"Extracellular vesicles: evolving factors in stem cell biology","volume":"2016","author":"Nawaz","year":"2016","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.lfs.2020.117447_bb0340","doi-asserted-by":"crossref","first-page":"754","DOI":"10.5966\/sctm.2015-0197","article-title":"Mesenchymal stromal cell-derived extracellular vesicles protect the fetal brain after hypoxia-ischemia","volume":"5","author":"Ophelders","year":"2016","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0345","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1083\/jcb.101.3.942","article-title":"Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes","volume":"101","author":"Pan","year":"1985","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.lfs.2020.117447_bb0350","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1111\/jth.12602","article-title":"Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing","volume":"12","author":"Pol","year":"2014","journal-title":"Journal of Thrombosis and Haemostasis."},{"key":"10.1016\/j.lfs.2020.117447_bb0355","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s12964-019-0390-y","article-title":"Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications","volume":"17","author":"Rahbarghazi","year":"2019","journal-title":"Cell Communication and Signaling."},{"key":"10.1016\/j.lfs.2020.117447_bb0360","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s13287-017-0478-5","article-title":"The effects of glomerular and tubular renal progenitors and derived extracellular vesicles on recovery from acute kidney injury","volume":"8","author":"Ranghino","year":"2017","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.lfs.2020.117447_bb0365","doi-asserted-by":"crossref","first-page":"5542","DOI":"10.1002\/adma.201504009","article-title":"The exosome-a naturally secreted nanoparticle and its application to wound healing","volume":"28","author":"Rani","year":"2016","journal-title":"Adv. Mater."},{"key":"10.1016\/j.lfs.2020.117447_bb0370","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1038\/sj.leu.2404296","article-title":"Membrane-derived microvesicles: important and underappreciated mediators of cell-to-cell communication","volume":"20","author":"Ratajczak","year":"2006","journal-title":"Leukemia."},{"key":"10.1016\/j.lfs.2020.117447_bb0375","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.bcp.2011.02.011","article-title":"Exosomes as intercellular signalosomes and pharmacological effectors","volume":"81","author":"Record","year":"2011","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.lfs.2020.117447_bb0380","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0044092","article-title":"Bone marrow-derived mesenchymal stem cells repaired but did not prevent gentamicin-induced acute kidney injury through paracrine effects in rats","volume":"7","author":"Reis","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2020.117447_bb0385","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s00441-018-2895-x","article-title":"Diabetic sera disrupted the normal exosome signaling pathway in human mesenchymal stem cells in vitro","volume":"374","author":"Rezaie","year":"2018","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0390","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/adhm.201200197","article-title":"Engineering the regenerative microenvironment with biomaterials","volume":"2","author":"Rice","year":"2013","journal-title":"Advanced Healthcare Materials."},{"key":"10.1016\/j.lfs.2020.117447_bb0395","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/nri3622","article-title":"Regulation of immune responses by extracellular vesicles","volume":"14","author":"Robbins","year":"2014","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.lfs.2020.117447_bb0400","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.yjmcc.2010.09.001","article-title":"Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes","volume":"50","author":"Rogers","year":"2011","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.lfs.2020.117447_bb0405","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.3389\/fmicb.2015.01132","article-title":"Extracellular vesicles from infected cells: potential for direct pathogenesis","volume":"6","author":"Schwab","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.lfs.2020.117447_bb0410","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/35070019","article-title":"Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing","volume":"3","author":"Sebbagh","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.lfs.2020.117447_bb0415","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1089\/scd.2014.0316","article-title":"Mesenchymal stem cell exosomes induce proliferation and migration of normal and chronic wound fibroblasts, and enhance angiogenesis in vitro","volume":"24","author":"Shabbir","year":"2015","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.lfs.2020.117447_bb0420","doi-asserted-by":"crossref","first-page":"904","DOI":"10.3389\/fphys.2017.00904","article-title":"GMSC-derived exosomes combined with a chitosan\/silk hydrogel sponge accelerates wound healing in a diabetic rat skin defect model","volume":"8","author":"Shi","year":"2017","journal-title":"Front. Physiol."},{"key":"10.1016\/j.lfs.2020.117447_bb0425","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/146764","article-title":"Complements and the wound healing cascade: an updated review","volume":"2013","author":"Sinno","year":"2013","journal-title":"Plastic Surgery International."},{"key":"10.1016\/j.lfs.2020.117447_bb0430","doi-asserted-by":"crossref","first-page":"792","DOI":"10.5966\/sctm.2012-0088","article-title":"Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds","volume":"1","author":"Skardal","year":"2012","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0435","doi-asserted-by":"crossref","first-page":"3307","DOI":"10.1002\/adma.200802106","article-title":"Hydrogels in regenerative medicine","volume":"21","author":"Slaughter","year":"2009","journal-title":"Adv. Mater."},{"key":"10.1016\/j.lfs.2020.117447_bb0440","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1007\/s00289-018-2480-1","article-title":"Magnetic PVA\/laponite RD hydrogel nanocomposites for adsorption of model protein BSA","volume":"76","author":"Soleymani","year":"2019","journal-title":"Polym. Bull."},{"key":"10.1016\/j.lfs.2020.117447_bb0445","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1034\/j.1600-0854.2002.30502.x","article-title":"The biogenesis and functions of exosomes","volume":"3","author":"Stoorvogel","year":"2002","journal-title":"Traffic."},{"key":"10.1016\/j.lfs.2020.117447_bb0450","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1038\/mt.2010.105","article-title":"A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes","volume":"18","author":"Sun","year":"2010","journal-title":"Mol. Ther."},{"key":"10.1016\/j.lfs.2020.117447_bb0455","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jbiotec.2013.03.013","article-title":"Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection","volume":"165","author":"Takahashi","year":"2013","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.lfs.2020.117447_bb0460","doi-asserted-by":"crossref","first-page":"736","DOI":"10.5966\/sctm.2016-0275","article-title":"Chitosan wound dressings incorporating exosomes derived from microRNA-126-overexpressing synovium mesenchymal stem cells provide sustained release of exosomes and heal full-thickness skin defects in a diabetic rat model","volume":"6","author":"Tao","year":"2017","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0465","doi-asserted-by":"crossref","first-page":"3871","DOI":"10.1007\/s00018-013-1290-8","article-title":"Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?","volume":"70","author":"Teixeira","year":"2013","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.lfs.2020.117447_bb0470","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1021\/bm030067p","article-title":"Thermally cross-linked oligo (poly (ethylene glycol) fumarate) hydrogels support osteogenic differentiation of encapsulated marrow stromal cells in vitro","volume":"5","author":"Temenoff","year":"2004","journal-title":"Biomacromolecules."},{"key":"10.1016\/j.lfs.2020.117447_bb0475","doi-asserted-by":"crossref","first-page":"956","DOI":"10.3390\/ijms18050956","article-title":"Association of extracellular membrane vesicles with cutaneous wound healing","volume":"18","author":"Than","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2020.117447_bb0480","first-page":"3.22.1","article-title":"Isolation and characterization of exosomes from cell culture supernatants and biological fluids","author":"Th\u00e9ry","year":"2006","journal-title":"Current Protocols in Cell Biology"},{"key":"10.1016\/j.lfs.2020.117447_bb0485","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.scr.2008.02.002","article-title":"Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium","volume":"1","author":"Timmers","year":"2007","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0490","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.scr.2011.01.001","article-title":"Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction","volume":"6","author":"Timmers","year":"2011","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0495","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1126\/science.1153124","article-title":"Ceramide triggers budding of exosome vesicles into multivesicular endosomes","volume":"319","author":"Trajkovic","year":"2008","journal-title":"Science."},{"key":"10.1016\/j.lfs.2020.117447_bb0500","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0005-2736(81)90512-5","article-title":"Exfoliation of membrane ecto-enzymes in the form of micro-vesicles","volume":"645","author":"Trams","year":"1981","journal-title":"Biochimica et Biophysica Acta (BBA)-Biomembranes."},{"key":"10.1016\/j.lfs.2020.117447_bb0505","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/term.231","article-title":"Micropatterned three-dimensional hydrogel system to study human endothelial-mesenchymal stem cell interactions","volume":"4","author":"Trkov","year":"2010","journal-title":"J. Tissue Eng. Regen. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0510","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/3548917","article-title":"The immunomodulatory potential of Wharton\u2019s jelly mesenchymal stem\/stromal cells","volume":"2019","author":"Vieira Paladino","year":"2019","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.lfs.2020.117447_bb0515","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1002\/adhm.201600308","article-title":"Exosomes from cardiomyocyte progenitor cells and mesenchymal stem cells stimulate angiogenesis via EMMPRIN","volume":"5","author":"Vrijsen","year":"2016","journal-title":"Advanced Healthcare Materials."},{"key":"10.1016\/j.lfs.2020.117447_bb0520","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s13287-016-0463-4","article-title":"Pre-incubation with hucMSC-exosomes prevents cisplatin-induced nephrotoxicity by activating autophagy","volume":"8","author":"Wang","year":"2017","journal-title":"Stem Cell Res Ther"},{"key":"10.1016\/j.lfs.2020.117447_bb0525","doi-asserted-by":"crossref","first-page":"65","DOI":"10.7150\/thno.29766","article-title":"Engineering bioactive self-healing antibacterial exosomes hydrogel for promoting chronic diabetic wound healing and complete skin regeneration","volume":"9","author":"Wang","year":"2019","journal-title":"Theranostics."},{"key":"10.1016\/j.lfs.2020.117447_bb0530","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1161\/STROKEAHA.116.015204","article-title":"MicroRNA-17\u201392 cluster in exosomes enhance neuroplasticity and functional recovery after stroke in rats","volume":"48","author":"Xin","year":"2017","journal-title":"Stroke."},{"key":"10.1016\/j.lfs.2020.117447_bb0535","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1038\/jcbfm.2013.152","article-title":"Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats","volume":"33","author":"Xin","year":"2013","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.lfs.2020.117447_bb0540","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1002\/stem.1409","article-title":"MiR-133b promotes neural plasticity and functional recovery after treatment of stroke with multipotent mesenchymal stromal cells in rats via transfer of exosome-enriched extracellular particles","volume":"31","author":"Xin","year":"2013","journal-title":"Stem Cells"},{"key":"10.1016\/j.lfs.2020.117447_bb0545","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1016\/j.progpolymsci.2014.07.006","article-title":"In situ-forming injectable hydrogels for regenerative medicine","volume":"39","author":"Yang","year":"2014","journal-title":"Prog. Polym. Sci."},{"key":"10.1016\/j.lfs.2020.117447_bb0550","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9742034","article-title":"Umbilical cord-derived mesenchymal stem cells relieve hindlimb ischemia through enhancing angiogenesis in tree shrews","volume":"2016","author":"Yin","year":"2016","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.lfs.2020.117447_bb0555","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s40364-019-0159-x","article-title":"Exosomes from mesenchymal stem\/stromal cells: a new therapeutic paradigm","volume":"7","author":"Yin","year":"2019","journal-title":"Biomarker Research."},{"key":"10.1016\/j.lfs.2020.117447_bb0560","doi-asserted-by":"crossref","first-page":"4142","DOI":"10.3390\/ijms15034142","article-title":"Exosomes derived from mesenchymal stem cells","volume":"15","author":"Yu","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2020.117447_bb0565","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1002\/stem.1771","article-title":"HucMSC-exosome mediated-Wnt4 signaling is required for cutaneous wound healing","volume":"33","author":"Zhang","year":"2015","journal-title":"Stem Cells"},{"key":"10.1016\/j.lfs.2020.117447_bb0570","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1159\/000443413","article-title":"Mesenchymal stromal cell-derived extracellular vesicles protect against acute kidney injury through anti-oxidation by enhancing Nrf2\/ARE activation in rats","volume":"41","author":"Zhang","year":"2016","journal-title":"Kidney Blood Press. Res."},{"key":"10.1016\/j.lfs.2020.117447_bb0575","first-page":"9","article-title":"The anti-oxidative role of micro-vesicles derived from human Wharton-jelly mesenchymal stromal cells through NOX2\/gp91 (phox) suppression in alleviating renal ischemia-reperfusion injury in rats","volume":"e92129","author":"Zhang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2020.117447_bb0580","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/jcb.21460","article-title":"Mechanisms that mediate stem cell self-renewal and differentiation","volume":"103","author":"Zhang","year":"2008","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.lfs.2020.117447_bb0585","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12967-015-0417-0","article-title":"Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis","volume":"13","author":"Zhang","year":"2015","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0590","doi-asserted-by":"crossref","first-page":"30081","DOI":"10.1021\/acsami.8b08449","article-title":"Enhanced therapeutic effects of mesenchymal stem cell-derived exosomes with an injectable hydrogel for hindlimb ischemia treatment","volume":"10","author":"Zhang","year":"2018","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.lfs.2020.117447_bb0595","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1016\/j.joca.2016.06.022","article-title":"Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration","volume":"24","author":"Zhang","year":"2016","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.lfs.2020.117447_bb0600","doi-asserted-by":"crossref","first-page":"856","DOI":"10.3171\/2014.11.JNS14770","article-title":"Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury","volume":"122","author":"Zhang","year":"2015","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.lfs.2020.117447_bb0605","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.neuint.2016.08.003","article-title":"Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury","volume":"111","author":"Zhang","year":"2017","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.lfs.2020.117447_bb0610","doi-asserted-by":"crossref","first-page":"2809","DOI":"10.1002\/adfm.201504943","article-title":"Injectable stem cell-laden photocrosslinkable microspheres fabricated using microfluidics for rapid generation of osteogenic tissue constructs","volume":"26","author":"Zhao","year":"2016","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.lfs.2020.117447_bb0615","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1007\/s10856-013-4987-1","article-title":"Rapidly in situ forming adhesive hydrogel based on a PEG-maleimide modified polypeptide through Michael addition","volume":"24","author":"Zhou","year":"2013","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"10.1016\/j.lfs.2020.117447_bb0620","doi-asserted-by":"crossref","first-page":"824","DOI":"10.3389\/fimmu.2018.00824","article-title":"Targeting and therapy of glioblastoma in a mouse model using exosomes derived from natural killer cells","volume":"9","author":"Zhu","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.lfs.2020.117447_bb0625","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1038\/mt.2011.164","article-title":"Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain","volume":"19","author":"Zhuang","year":"2011","journal-title":"Mol. Ther."},{"key":"10.1016\/j.lfs.2020.117447_bb0630","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/scrt428","article-title":"Microvesicles derived from human Wharton\u2019s jelly mesenchymal stromal cells ameliorate renal ischemia-reperfusion injury in rats by suppressing CX3CL1","volume":"5","author":"Zou","year":"2014","journal-title":"Stem Cell Res Ther"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320520301958?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320520301958?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T13:33:04Z","timestamp":1735392784000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320520301958"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":126,"alternative-id":["S0024320520301958"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2020.117447","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Free and hydrogel encapsulated exosome-based therapies in regenerative medicine","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2020.117447","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117447"}}