{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T04:48:44Z","timestamp":1740113324219,"version":"3.37.3"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008233","name":"School of Medicine, Shanghai Jiao Tong University","doi-asserted-by":"publisher","award":["BXJ201840"],"award-info":[{"award-number":["BXJ201840"]}],"id":[{"id":"10.13039\/501100008233","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.lfs.2020.117537","type":"journal-article","created":{"date-parts":[[2020,3,9]],"date-time":"2020-03-09T16:18:33Z","timestamp":1583770713000},"page":"117537","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Urethral dysfunction and alterations of nitric oxide mechanisms in streptozotocin-induced diabetic rats with or without low-dose insulin treatment"],"prefix":"10.1016","volume":"249","author":[{"given":"Nailong","family":"Cao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo C.","family":"Alexandre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Gotoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Kurobe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinsuke","family":"Mizoguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baojun","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.lfs.2020.117537_bb0005","first-page":"327","article-title":"Neural control of the lower urinary tract","volume":"5","author":"de Groat","year":"2015","journal-title":"Compr. Physiol."},{"issue":"7","key":"10.1016\/j.lfs.2020.117537_bb0010","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/nau.22639","article-title":"Sphincter electromyography in diabetes mellitus and multiple system atrophy","volume":"34","author":"Jian","year":"2015","journal-title":"Neurourol. Urodyn."},{"issue":"5","key":"10.1016\/j.lfs.2020.117537_bb0015","doi-asserted-by":"crossref","first-page":"F887","DOI":"10.1152\/ajprenal.00489.2016","article-title":"Path of translational discovery of urological complications of obesity and diabetes","volume":"312","author":"Daneshgari","year":"2017","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"5","key":"10.1016\/j.lfs.2020.117537_bb0020","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1097\/01.ju.0000121283.92963.05","article-title":"Urethral dysfunction in diabetic rats","volume":"171","author":"Torimoto","year":"2004","journal-title":"J. Urol."},{"issue":"5","key":"10.1016\/j.lfs.2020.117537_bb0025","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1016\/j.juro.2007.06.042","article-title":"Diabetic urethropathy compounds the effects of diabetic cystopathy","volume":"178","author":"Yang","year":"2007","journal-title":"J. Urol."},{"issue":"2","key":"10.1016\/j.lfs.2020.117537_bb0030","doi-asserted-by":"crossref","first-page":"91","DOI":"10.5213\/inj.1938050.025","article-title":"Time-dependent changes of urethral function in diabetes mellitus: a review","volume":"23","author":"Cao","year":"2019","journal-title":"Int. Neurourol. J."},{"issue":"6 Suppl","key":"10.1016\/j.lfs.2020.117537_bb0035","first-page":"S18","article-title":"Diabetic bladder dysfunction: current translational knowledge","volume":"182","author":"Daneshgari","year":"2009","journal-title":"J. Urol."},{"issue":"1","key":"10.1016\/j.lfs.2020.117537_bb0040","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/S0022-5347(06)00582-9","article-title":"Time dependent changes in diabetic cystopathy in rats include compensated and decompensated bladder function","volume":"176","author":"Daneshgari","year":"2006","journal-title":"J. Urol."},{"issue":"3","key":"10.1016\/j.lfs.2020.117537_bb0045","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.juro.2012.08.222","article-title":"Roles of polyuria and hyperglycemia in bladder dysfunction in diabetes","volume":"189","author":"Xiao","year":"2013","journal-title":"J. Urol."},{"issue":"6","key":"10.1016\/j.lfs.2020.117537_bb0050","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1016\/S0022-5347(01)67391-9","article-title":"Neural control of urethral outlet activity in vivo: role of nitric oxide","volume":"153","author":"Bennett","year":"1995","journal-title":"J. Urol."},{"issue":"5","key":"10.1016\/j.lfs.2020.117537_bb0055","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1016\/S0022-5347(05)65135-X","article-title":"Localization and role of nitric oxide synthase and endogenous nitric oxide synthase inhibitors in the rabbit lower urinary tract","volume":"167","author":"Masuda","year":"2002","journal-title":"J. Urol."},{"key":"10.1016\/j.lfs.2020.117537_bb0060","series-title":"Lower Urinary Tract Symptoms","article-title":"Tadalafil, a phosphodiesterase type 5 inhibitor, restores urethra and detrusor function in the initial phase of diabetes in rats","author":"Gotoh","year":"2019"},{"issue":"4","key":"10.1016\/j.lfs.2020.117537_bb0065","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/nau.23481","article-title":"Age-associated urethral dysfunction in urethane-anesthetized rats","volume":"37","author":"Kimura","year":"2018","journal-title":"Neurourol. Urodyn."},{"issue":"6","key":"10.1016\/j.lfs.2020.117537_bb0070","doi-asserted-by":"crossref","first-page":"F1026","DOI":"10.1152\/ajprenal.00013.2017","article-title":"How important is the alpha1-adrenoceptor in primate and rodent proximal urethra? Sex differences in the contribution of alpha1-adrenoceptor to urethral contractility","volume":"312","author":"Alexandre","year":"2017","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"2","key":"10.1016\/j.lfs.2020.117537_bb0075","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/S0022-5347(01)65209-1","article-title":"Diabetic cystopathy: relationship to autonomic neuropathy detected by sympathetic skin response","volume":"157","author":"Ueda","year":"1997","journal-title":"J. Urol."},{"issue":"1\u20132","key":"10.1016\/j.lfs.2020.117537_bb0080","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s11010-018-3338-4","article-title":"Type 1 diabetes mellitus induces structural changes and molecular remodelling in the rat kidney","volume":"449","author":"Singh","year":"2018","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.lfs.2020.117537_bb0085","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.bbr.2016.10.031","article-title":"Autophagy-lysosome dysfunction is involved in Abeta deposition in STZ-induced diabetic rats","volume":"320","author":"Ma","year":"2017","journal-title":"Behav. Brain Res."},{"issue":"4","key":"10.1016\/j.lfs.2020.117537_bb0090","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.urology.2008.11.026","article-title":"Diabetes-induced alternations in biomechanical properties of urinary bladder wall in rats","volume":"73","author":"Wang","year":"2009","journal-title":"Urology"},{"issue":"6 Pt 2","key":"10.1016\/j.lfs.2020.117537_bb0095","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1161\/01.HYP.23.6.1121","article-title":"Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions","volume":"23","author":"Forstermann","year":"1994","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.lfs.2020.117537_bb0100","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0922-4106(94)90185-6","article-title":"Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract","volume":"268","author":"Persson","year":"1994","journal-title":"Eur. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.lfs.2020.117537_bb0105","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S0022-5347(05)68627-2","article-title":"Alterations in the nitric oxide synthase binding sites and non-adrenergic, non-cholinergic mediated smooth muscle relaxation in the diabetic rabbit bladder outlet: possible relevance to the pathogenesis of diabetic cystopathy","volume":"162","author":"Mumtaz","year":"1999","journal-title":"J. Urol."},{"key":"10.1016\/j.lfs.2020.117537_bb0110","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.autneu.2014.03.002","article-title":"Nitrergic relaxations and phenylephrine contractions are not compromised in isolated urethra in a rat model of diabetes","volume":"183","author":"Al-Noah","year":"2014","journal-title":"Auton. Neurosci."},{"issue":"5","key":"10.1016\/j.lfs.2020.117537_bb0115","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1002\/nau.20543","article-title":"External urethral sphincter activity in diabetic rats","volume":"27","author":"Liu","year":"2008","journal-title":"Neurourol. Urodyn."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432052030285X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432052030285X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,28]],"date-time":"2024-12-28T13:33:35Z","timestamp":1735392815000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002432052030285X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":23,"alternative-id":["S002432052030285X"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2020.117537","relation":{},"ISSN":["0024-3205"],"issn-type":[{"type":"print","value":"0024-3205"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urethral dysfunction and alterations of nitric oxide mechanisms in streptozotocin-induced diabetic rats with or without low-dose insulin treatment","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2020.117537","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"117537"}}