{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T11:36:34Z","timestamp":1791459394225,"version":"4.3.4"},"reference-count":113,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.lfs.2020.118767","type":"journal-article","created":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T02:05:03Z","timestamp":1605492303000},"page":"118767","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Advances of microfluidic technology in reproductive biology"],"prefix":"10.1016","volume":"265","author":[{"given":"Aylin","family":"Nikshad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afsoon","family":"Aghlmandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Safaralizadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leili","family":"Aghebati-Maleki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid Ebrahimi","family":"Warkiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhad Motavalli","family":"Khiavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Yousefi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2020.118767_bb0005","series-title":"Conventional In-Vitro Fertilisation Versus Intracytoplasmic Sperm Injection for the Treatment of Non-male-Factor Infertility: A Randomised Controlled Trial","first-page":"2075","volume":"357","author":"Bhattacharya","year":"2001"},{"key":"10.1016\/j.lfs.2020.118767_bb0010","series-title":"Managing Infertility in Primary Care","first-page":"440","volume":"26","author":"Allan","year":"2015"},{"key":"10.1016\/j.lfs.2020.118767_bb0015","series-title":"Cell therapy in female infertility-related diseases: Emphasis on recurrent miscarriage and repeated implantation failure.","first-page":"118181","volume":"258","author":"Pourakbari,","year":"2020"},{"key":"10.1016\/j.lfs.2020.118767_bb0020","series-title":"Male Infertility-the Other Side of the Equation","first-page":"641","volume":"46","author":"Katz","year":"2017"},{"key":"10.1016\/j.lfs.2020.118767_bb0025","series-title":"Clinical Evaluation of Spermatogenic Activity of Processed Shilajit in Oligospermia","first-page":"48","volume":"42","author":"Biswas","year":"2010"},{"key":"10.1016\/j.lfs.2020.118767_bb0030","series-title":"World Health Organization Reference Values for Human Semen Characteristics","first-page":"231","volume":"16","author":"Cooper","year":"2010"},{"key":"10.1016\/j.lfs.2020.118767_bb0035","series-title":"Male Infertility: Lifestyle and Oriental Remedies","first-page":"93","volume":"56","author":"Mishra","year":"2012"},{"key":"10.1016\/j.lfs.2020.118767_bb0040","series-title":"Sperm Motility: Is Viscosity Fundamental to Progress?","first-page":"539","volume":"17","author":"Kirkman-Brown","year":"2011"},{"key":"10.1016\/j.lfs.2020.118767_bb0045","series-title":"Male Infertility: Lifestyle Factors and Holistic, Complementary, and Alternative Therapies","first-page":"410","volume":"18","author":"Yao","year":"2016"},{"key":"10.1016\/j.lfs.2020.118767_bb0050","series-title":"Causes of Male Infertility: A 9-year Prospective Monocentre Study on 1737 Patients with Reduced Total Sperm Counts","first-page":"18","volume":"32","author":"Punab","year":"2016"},{"key":"10.1016\/j.lfs.2020.118767_bb0055","series-title":"Effects of N-Acetyl-cysteine Supplementation on Sperm Quality, Chromatin Integrity and Level of Oxidative Stress in Infertile Men","first-page":"24","volume":"17","author":"Jannatifar","year":"2019"},{"key":"10.1016\/j.lfs.2020.118767_bb0060","series-title":"Association between Infertility and Sexual Dysfunction in Men and Women","first-page":"353","volume":"4","author":"Berger","year":"2016"},{"key":"10.1016\/j.lfs.2020.118767_bb0065","series-title":"The Epidemiology of Male Infertility","first-page":"195","volume":"41","author":"Winters","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0070","article-title":"Cell therapy in female infertility-related diseases: emphasis on recurrent miscarriage and repeated implantation failure","volume":"258","author":"Pourakbari","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.lfs.2020.118767_bb0075","series-title":"Relationship between the Developmental Programs Controlling Nuclear and Cytoplasmic Maturation of Mouse Oocytes","first-page":"1","volume":"164","author":"Eppig","year":"1994"},{"issue":"1","key":"10.1016\/j.lfs.2020.118767_bb0080","first-page":"35","article-title":"Downregulation of extracellular matrix and cell adhesion molecules in cumulus cells of infertile polycystic ovary syndrome women with and without insulin resistance","volume":"21","author":"Hassani","year":"2019","journal-title":"Cell J."},{"key":"10.1016\/j.lfs.2020.118767_bb0085","series-title":"Approach to the Patient: Contraception in Women with Polycystic Ovary Syndrome","first-page":"794","volume":"100","author":"Yildiz","year":"2015"},{"key":"10.1016\/j.lfs.2020.118767_bb0090","series-title":"Heritability of Polycystic Ovary Syndrome in a Dutch Twin-family Study","first-page":"2100","volume":"91","author":"Vink","year":"2006"},{"key":"10.1016\/j.lfs.2020.118767_bb0095","series-title":"Prevalence of Polycystic Ovary Syndrome (PCOS) in First-degree Relatives of Patients with PCOS","first-page":"53","volume":"75","author":"Kahsar-Miller","year":"2001"},{"key":"10.1016\/j.lfs.2020.118767_bb0100","series-title":"Evidence for a Genetic Basis for Hyperandrogenemia in Polycystic Ovary Syndrome","first-page":"14956","volume":"95","author":"Legro","year":"1998"},{"key":"10.1016\/j.lfs.2020.118767_bb0105","series-title":"A Twin Study of Polycystic Ovary Syndrome and Lipids","first-page":"111","volume":"11","author":"Jahanfar","year":"1997"},{"key":"10.1016\/j.lfs.2020.118767_bb0110","series-title":"Large-Scale Genome-Wide Meta-Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria","first-page":"e1007813","volume":"14","author":"Day","year":"2018"},{"key":"10.1016\/j.lfs.2020.118767_bb0115","series-title":"The Experience of Infertility: A Review of Recent Literature","first-page":"140","volume":"32","author":"Greil","year":"2010"},{"key":"10.1016\/j.lfs.2020.118767_bb0120","series-title":"Vitamin D and Female Fertility","first-page":"145","volume":"26","author":"Lerchbaum","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0125","series-title":"The Role of Vitamin D in Impaired Fertility Treatment","first-page":"756","volume":"34","author":"Grzechocinska","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0130","series-title":"History of Infertility Relates to Increased Risk of Gestational Diabetes Mellitus: A Meta-analysis","first-page":"2","volume":"10","author":"Wang","year":"2017"},{"key":"10.1016\/j.lfs.2020.118767_bb0135","author":"Thomas","year":"2019"},{"key":"10.1016\/j.lfs.2020.118767_bb0140","series-title":"World Collaborative Report on Assisted Reproductive Technology","first-page":"2310","volume":"24","author":"I.C.f.M.A.R.T","year":"2002"},{"key":"10.1016\/j.lfs.2020.118767_bb0145","series-title":"Systematic Review of Worldwide Trends in Assisted Reproductive Technology 2004\u20132013","first-page":"6","volume":"15","author":"Kushnir","year":"2017"},{"key":"10.1016\/j.lfs.2020.118767_bb0150","series-title":"The Origins and the Future of Microfluidics","first-page":"368","volume":"442","author":"Whitesides","year":"2006"},{"key":"10.1016\/j.lfs.2020.118767_bb0155","series-title":"Microfluidics for Sperm Research","first-page":"221","volume":"33","author":"Knowlton","year":"2015"},{"key":"10.1016\/j.lfs.2020.118767_bb0160","series-title":"Integration of Single Oocyte Trapping, In Vitro Fertilization and Embryo Culture in a Microwell-Structured Microfluidic Device","first-page":"2848","volume":"10","author":"Han","year":"2010"},{"key":"10.1016\/j.lfs.2020.118767_bb0165","series-title":"Embryo Formation from Low Sperm Concentration by Using Dielectrophoretic Force","first-page":"022404","volume":"9","author":"Huang","year":"2015"},{"key":"10.1016\/j.lfs.2020.118767_bb0170","series-title":"Commercialization of Microfluidic Devices","first-page":"347","volume":"32","author":"Volpatti","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0175","series-title":"There\u2019s Plenty of Room at the Bottom","author":"Feynman","year":"1960"},{"key":"10.1016\/j.lfs.2020.118767_bb0180","series-title":"Oocyte Degeneration after Intracytoplasmic Sperm Injection: A Multivariate Analysis to Assess its Importance as a Laboratory or Clinical Marker","first-page":"1736","volume":"85","author":"Rosen","year":"2006"},{"key":"10.1016\/j.lfs.2020.118767_bb0185","series-title":"Biotechnology at Low Reynolds Numbers","first-page":"3430","volume":"71","author":"Brody","year":"1996"},{"key":"10.1016\/j.lfs.2020.118767_bb0190","series-title":"Microfluidic Devices for DNA Sequencing: Sample Preparation and Electrophoretic Analysis","first-page":"42","volume":"14","author":"Paegel","year":"2003"},{"key":"10.1016\/j.lfs.2020.118767_bb0195","series-title":"International Committee for Monitoring Assisted Reproductive Technologies World Report: Assisted Reproductive Technology 2008, 2009 and 2010","first-page":"1588","volume":"31","author":"Dyer","year":"2016"},{"key":"10.1016\/j.lfs.2020.118767_bb0200","series-title":"Microphysiological Modeling of the Reproductive Tract: A Fertile Endeavor","first-page":"1192","volume":"239","author":"Eddie","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0205","series-title":"A Microphysiological Model of the Human Placental Barrier","first-page":"3065","volume":"16","author":"Blundell","year":"2016"},{"key":"10.1016\/j.lfs.2020.118767_bb0210","series-title":"Artificial uterus on a microfluidic chip","first-page":"467","volume":"41","author":"Wei-Xuan","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0215","series-title":"Assisted Reproductive Technology and Major Structural Birth Defects in the United States","first-page":"360","volume":"24","author":"Reefhuis","year":"2008"},{"key":"10.1016\/j.lfs.2020.118767_bb0220","series-title":"Semen Analysis at the Turn of the Century: An Evaluation of Potential Uses of New Sperm Function Assays","first-page":"65","volume":"44","author":"Carrell","year":"2000"},{"key":"10.1016\/j.lfs.2020.118767_bb0225","series-title":"Morphology and the Sperm Penetration Assay","first-page":"39","volume":"79","author":"Zahalsky","year":"2003"},{"key":"10.1016\/j.lfs.2020.118767_bb0230","series-title":"Population Study of Causes, Treatment, and Outcome of Infertility","first-page":"272","volume":"292","author":"Haxton","year":"1986"},{"key":"10.1016\/j.lfs.2020.118767_bb0235","series-title":"Population Study of Causes, Treatment, and Outcome of Infertility","first-page":"1693","volume":"291","author":"Hull","year":"1985"},{"key":"10.1016\/j.lfs.2020.118767_bb0240","series-title":"Asthenozoospermia: Analysis of a Large Population","first-page":"343","volume":"49","author":"Curi","year":"2003"},{"key":"10.1016\/j.lfs.2020.118767_bb0245","series-title":"Teratozoospermia: Spotlight on the Main Genetic Actors in the Human","first-page":"455","volume":"21","author":"Coutton","year":"2015"},{"key":"10.1016\/j.lfs.2020.118767_bb0250","series-title":"Mutations in DNAH1, which Encodes an Inner Arm Heavy Chain Dynein, Lead to Male Infertility from Multiple Morphological Abnormalities of the Sperm Flagella","first-page":"95","volume":"94","author":"Khelifa","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0255","series-title":"Clinically Relevant Enhancement of Human Sperm Motility Using Compounds with Reported Phosphodiesterase Inhibitor Activity","first-page":"2123","volume":"29","author":"Tardif","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0260","series-title":"Decreased Responsiveness to Progesterone of Spermatozoa in Oligozoospermic Patients","first-page":"17","volume":"14","author":"Falsetti","year":"1993"},{"key":"10.1016\/j.lfs.2020.118767_bb0265","series-title":"Ca2+ Signals Generated by CatSper and Ca2+ Stores Regulate Different Behaviors in Human Sperm","first-page":"6248","volume":"288","author":"Alasmari","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0270","series-title":"And Development, Sugar-Coated Sperm: Unraveling the Functions of the Mammalian Sperm Glycocalyx","first-page":"635","volume":"82","author":"Tecle","year":"2015"},{"key":"10.1016\/j.lfs.2020.118767_bb0275","series-title":"Impact of Glycosylation on the Unimpaired Functions of the Sperm","first-page":"77","volume":"42","author":"Cheon","year":"2015"},{"key":"10.1016\/j.lfs.2020.118767_bb0280","series-title":"%J World Health Organization","first-page":"287","author":"World Health Organization","year":"2010"},{"key":"10.1016\/j.lfs.2020.118767_bb0285","series-title":"Isolation of Motile Spermatozoa from Semen Samples Using Microfluidics","first-page":"75","volume":"7","author":"Schuster","year":"2003"},{"key":"10.1016\/j.lfs.2020.118767_bb0290","series-title":"Passively Driven Integrated Microfluidic System for Separation of Motile Sperm","first-page":"1671","volume":"75","author":"Cho","year":"2003"},{"key":"10.1016\/j.lfs.2020.118767_bb0295","series-title":"Application of Microfluidic Technologies to Human Assisted Reproduction","first-page":"257","volume":"23","author":"Smith","year":"2017"},{"key":"10.1016\/j.lfs.2020.118767_bb0300","series-title":"Sperm Chemotaxis in Marine Invertebrates\u2014Molecules and Mechanisms","first-page":"487","volume":"208","author":"Kaupp","year":"2006"},{"key":"10.1016\/j.lfs.2020.118767_bb0305","series-title":"Centrifugation of Human Spermatozoa Induces Sublethal Damage; Separation of Human Spermatozoa from Seminal Plasma by a Dextran Swim-up Procedure without Centrifugation Extends their Motile Lifetime","first-page":"1087","volume":"8","author":"Alvarez","year":"1993"},{"key":"10.1016\/j.lfs.2020.118767_bb0310","series-title":"Significance of Reactive Oxygen Species and Antioxidants in Defining the Efficacy of Sperm Preparation Techniques","first-page":"367","volume":"9","author":"Aitken","year":"1988"},{"key":"10.1016\/j.lfs.2020.118767_bb0315","series-title":"Analysis of DNA Fragmentation, Plasma Membrane Translocation of Phosphatidylserine and Oxidative Stress in Human Spermatozoa","first-page":"1338","volume":"15","author":"Barroso","year":"2000"},{"key":"10.1016\/j.lfs.2020.118767_bb0320","series-title":"DNA Integrity in Human Spermatozoa: Relationships with Semen Quality","first-page":"33","volume":"21","author":"Irvine","year":"2000"},{"key":"10.1016\/j.lfs.2020.118767_bb0325","series-title":"Potential Adverse Effect of Sperm DNA Damage on Embryo Quality after ICSI","first-page":"3476","volume":"20","author":"Zini","year":"2005"},{"key":"10.1016\/j.lfs.2020.118767_bb0330","series-title":"Sperm DNA Fragmentation Decreases the Pregnancy Rate in an Assisted Reproductive Technique","first-page":"1023","volume":"18","author":"Benchaib","year":"2003"},{"key":"10.1016\/j.lfs.2020.118767_bb0335","series-title":"Extent of Nuclear DNA Damage in Ejaculated Spermatozoa Impacts on Blastocyst Development after In Vitro Fertilization","first-page":"378","volume":"82","author":"Seli","year":"2004"},{"key":"10.1016\/j.lfs.2020.118767_bb0340","series-title":"Sperm Chromatin Structure Assay (SCSA\u00ae) Parameters Are Related to Fertilization, Blastocyst Development, and Ongoing Pregnancy in In Vitro Fertilization and Intracytoplasmic Sperm Injection Cycles","first-page":"1289","volume":"81","author":"Virro","year":"2004"},{"key":"10.1016\/j.lfs.2020.118767_bb0345","series-title":"Rapid Selection of Sperm with High DNA Integrity","first-page":"1142","volume":"14","author":"Nosrati","year":"2014"},{"issue":"3","key":"10.1016\/j.lfs.2020.118767_bb0350","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s10815-018-1375-2","article-title":"Effects of the microfluidic chip technique in sperm selection for intracytoplasmic sperm injection for unexplained infertility: a prospective, randomized controlled trial","volume":"36","author":"Yetkinel","year":"2019","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.lfs.2020.118767_bb0355","series-title":"Infertility, Mental Disorders and Well-Being\u2013A Nationwide Survey","first-page":"677","volume":"89","author":"Klemetti","year":"2010"},{"key":"10.1016\/j.lfs.2020.118767_bb0360","series-title":"Emotional Distress in Infertile Women and Failure of Assisted Reproductive Technologies: Meta-analysis of Prospective Psychosocial Studies","first-page":"d223","volume":"342","author":"Boivin","year":"2011"},{"key":"10.1016\/j.lfs.2020.118767_bb0365","series-title":"Phosphoric Acid and Phosphorylation Levels are Potential Biomarkers Indicating Developmental Competence of Matured Oocytes","first-page":"1527","volume":"144","author":"Ishigaki","year":"2019"},{"key":"10.1016\/j.lfs.2020.118767_bb0370","series-title":"New Molecular Markers for the Evaluation of Gamete Quality","first-page":"207","volume":"30","author":"Ruvolo","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0375","series-title":"What Criteria for the Definition of Oocyte Quality?","first-page":"132","volume":"1034","author":"Coticchio","year":"2004"},{"key":"10.1016\/j.lfs.2020.118767_bb0380","series-title":"Effects of Different Hyaluronidase Concentrations and Mechanical Procedures for Cumulus Cell Removal on the Outcome of Intracytoplasmic Sperm Injection","first-page":"2246","volume":"12","author":"Van de Velde","year":"1997"},{"key":"10.1016\/j.lfs.2020.118767_bb0385","series-title":"Germ Cell Protocols","first-page":"365","article-title":"Microfluidic removal of cumulus cells from mammalian zygotes","author":"Zeringue","year":"2004"},{"key":"10.1016\/j.lfs.2020.118767_bb0390","series-title":"Maternal, Perinatal and Long-Term Outcomes after Assisted Reproductive Techniques (ART): Implications for Clinical Practice","first-page":"13","volume":"170","author":"Talaulikar","year":"2013"},{"issue":"4","key":"10.1016\/j.lfs.2020.118767_bb0395","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1177\/2472630319851765","article-title":"IVF-on-a-chip: recent advances in microfluidics technology for in vitro fertilization","volume":"24","author":"Weng","year":"2019","journal-title":"SLAS Technol"},{"key":"10.1016\/j.lfs.2020.118767_bb0400","series-title":"Number of Embryos for Transfer Following In Vitro Fertilisation or Intra-Cytoplasmic Sperm Injection","first-page":"7","author":"Pandian","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0405","series-title":"Reducing Multiple Births in Assisted Reproduction Technology","first-page":"191","volume":"28","author":"Bhattacharya","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0410","series-title":"Multiple Gestation Associated with Infertility Therapy: An American Society for Reproductive Medicine Practice Committee Opinion","first-page":"825","volume":"97(4)","author":"Fertility, P.C.o.t.A.S.f.R.M.J","year":"2012"},{"key":"10.1016\/j.lfs.2020.118767_bb0415","series-title":"Cleavage Stage Versus Blastocyst Stage Embryo Transfer in Assisted Reproductive Technology","volume":"6","author":"Glujovsky","year":"2016"},{"key":"10.1016\/j.lfs.2020.118767_bb0420","series-title":"In Vitro Fertilization with Single Blastocyst-Stage Versus Single Cleavage-Stage Embryos","first-page":"1139","volume":"354","author":"Papanikolaou","year":"2006"},{"key":"10.1016\/j.lfs.2020.118767_bb0425","series-title":"Live Birth after Fresh Versus Frozen Single Blastocyst Transfer (Frefro-Blastocyst): Study Protocol for a Randomized Controlled Trial","first-page":"253","volume":"18","author":"Wei","year":"2017"},{"key":"10.1016\/j.lfs.2020.118767_bb0430","series-title":"Fresh Versus Frozen Embryo Transfer: Backing Clinical Decisions with Scientific and Clinical Evidence","first-page":"808","volume":"20","author":"Evans","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0435","series-title":"Correlation of Sperm Penetration Assay Score with Polyspermy Rate in In-Vitro Fertilization","first-page":"3","volume":"2","author":"Aoki","year":"2005"},{"key":"10.1016\/j.lfs.2020.118767_bb0440","series-title":"IVF within Microfluidic Channels Requires Lower Total Numbers and Lower Concentrations of Sperm","first-page":"477","volume":"21","author":"Suh","year":"2005"},{"key":"10.1016\/j.lfs.2020.118767_bb0445","series-title":"Criteria for Number of Embryos to Transfer: A Committee Opinion","first-page":"44","volume":"99","author":"Medicine, P.C.o.t.A.S.f.R., P.C.o.t.S.f.A.R.T.J. Fertility, and sterility","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0450","series-title":"A Microfluidic Device to Reduce Treatment Time of Intracytoplasmic Sperm Injection","first-page":"400","volume":"99","author":"Matsuura","year":"2013"},{"issue":"24","key":"10.1016\/j.lfs.2020.118767_bb0455","doi-asserted-by":"crossref","first-page":"3892","DOI":"10.1039\/C8LC01075G","article-title":"On-chip oocyte denudation from cumulus-oocyte complexes for assisted reproductive therapy","volume":"18","author":"Weng","year":"2018","journal-title":"Lab Chip"},{"key":"10.1016\/j.lfs.2020.118767_bb0460","series-title":"A Method for Culture of Micromanipulated Sheep Embryos and its use to Produce Monozygotic Twins","first-page":"298","volume":"277","author":"Willadsen","year":"1979"},{"key":"10.1016\/j.lfs.2020.118767_bb0465","series-title":"Embryonic Development in the Mouse Is Enhanced via Microchannel Culture","first-page":"186","volume":"4","author":"Raty","year":"2004"},{"key":"10.1016\/j.lfs.2020.118767_bb0470","series-title":"Comparison of Static and Dynamic Medium Environments for Culturing of Pre-implantation Mouse Embryos","first-page":"122","volume":"52","author":"Hickman","year":"2002"},{"key":"10.1016\/j.lfs.2020.118767_bb0475","series-title":"Computerized Microfluidic Cell Culture Using Elastomeric Channels and Braille Displays","first-page":"15861","volume":"101","author":"Gu","year":"2004"},{"key":"10.1016\/j.lfs.2020.118767_bb0480","series-title":"Dynamic Microfunnel Culture Enhances Mouse Embryo Development and Pregnancy Rates","first-page":"613","volume":"25","author":"Heo","year":"2010"},{"key":"10.1016\/j.lfs.2020.118767_bb0485","series-title":"Thinking Big by Thinking Small: Application of Microfluidic Technology to Improve ART","first-page":"1213","volume":"13","author":"Swain","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0490","series-title":"Semi-automated Morphometric Analysis of Human Embryos Can Reveal Correlations between Total Embryo Volume and Clinical Pregnancy","first-page":"627","volume":"28","author":"Paternot","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0495","series-title":"The Nature of Aneuploidy with Increasing Age of the Female Partner: A Review of 15,169 Consecutive Trophectoderm Biopsies Evaluated with Comprehensive Chromosomal Screening","first-page":"656","volume":"101","author":"Franasiak","year":"2014"},{"issue":"6","key":"10.1016\/j.lfs.2020.118767_bb0500","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1093\/humrep\/der037","volume":"26","year":"2011","journal-title":"Hum Reprod"},{"key":"10.1016\/j.lfs.2020.118767_bb0505","series-title":"Development of a Respirometric Biochip for Embryo Assessment","first-page":"1438","volume":"6","author":"O\u2019Donovan","year":"2006"},{"key":"10.1016\/j.lfs.2020.118767_bb0510","series-title":"Non-invasive Amino Acid Turnover Predicts Human Embryo Developmental Capacity","first-page":"999","volume":"17","author":"Houghton1","year":"2002"},{"key":"10.1016\/j.lfs.2020.118767_bb0515","series-title":"Noninvasive Assessment of Human Embryo Nutrient Consumption as a Measure of Developmental Potential","first-page":"1175","volume":"76","author":"Gardner","year":"2001"},{"key":"10.1016\/j.lfs.2020.118767_bb0520","series-title":"Ameliorating Effect of Selenium against Arsenic Induced Male Reproductive Toxicity in Rats","first-page":"107","volume":"38","author":"Jalaludeen","year":"2014"},{"key":"10.1016\/j.lfs.2020.118767_bb0525","series-title":"HTLV-III in the Semen and Blood of a Healthy Homosexual Man","first-page":"451","volume":"226","author":"Ho","year":"1984"},{"key":"10.1016\/j.lfs.2020.118767_bb0530","series-title":"Isolation of Giant Lampbrush Chromosomes From Living Oocytes of Frogs and Salamanders","first-page":"e54103","volume":"118","author":"Gall","year":"2016"},{"key":"10.1016\/j.lfs.2020.118767_bb0535","series-title":"The Use of Morphokinetic Parameters to Select all Embryos with Full Capacity to Implant","first-page":"703","volume":"30","author":"Chamayou","year":"2013"},{"key":"10.1016\/j.lfs.2020.118767_bb0540","series-title":"Long-Term Storage of Tissues by Cryopreservation: Critical Issues","first-page":"243","volume":"17","author":"Karlsson","year":"1996"},{"issue":"13","key":"10.1016\/j.lfs.2020.118767_bb0545","first-page":"1874","volume":"9","author":"Song","year":"2009","journal-title":"Microfluidics for cryopreservation"},{"key":"10.1016\/j.lfs.2020.118767_bb0550","series-title":"Effect of Osmotic Stress on the Developmental Competence of Germinal Vesicle and Metaphase II Stage Bovine Cumulus Oocyte Complexes and its Relevance to Cryopreservation","first-page":"212","volume":"55","author":"Agca","year":"2000"},{"key":"10.1016\/j.lfs.2020.118767_bb0555","series-title":"Osmotic Stress as a Mechanism of Freezing Injury","first-page":"489","volume":"8","author":"Meryman","year":"1971"},{"key":"10.1016\/j.lfs.2020.118767_bb0560","series-title":"Comparison of Open and Closed Methods for Vitrification of Human Embryos and the Elimination of Potential Contamination","first-page":"608","volume":"11","author":"Kuwayama","year":"2005"},{"key":"10.1016\/j.lfs.2020.118767_bb0565","series-title":"Highly Efficient Vitrification Method for Cryopreservation of Human Oocytes","first-page":"300","volume":"11","author":"Kuwayama","year":"2005"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320520315204?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320520315204?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T20:43:26Z","timestamp":1758401006000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320520315204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":113,"alternative-id":["S0024320520315204"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2020.118767","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Advances of microfluidic technology in reproductive biology","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2020.118767","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"118767"}}