{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:36:33Z","timestamp":1788554193552,"version":"build-2803163510"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T00:00:00Z","timestamp":1641340800000},"content-version":"vor","delay-in-days":338,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.lfs.2020.118912","type":"journal-article","created":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T21:50:02Z","timestamp":1608155402000},"page":"118912","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Low-dose chlorine exposure impairs lung function, inflammation and oxidative stress in mice"],"prefix":"10.1016","volume":"267","author":[{"given":"Isabella Santos","family":"de Genaro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine Maria","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Degobbi Tenorio Quirino","family":"dos Santos Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah De Camargo Hizume","family":"Kunzler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Gabryela Busoletto","family":"Tripode","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Kurdejak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Nakamura","family":"Cordeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Pandolpho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariangela","family":"Macchione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thayse Regina","family":"Br\u00fcggemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo Paula","family":"Vieira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milton Arruda","family":"Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iolanda","family":"de F\u00e1tima Lopes Calvo Tib\u00e9rio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz Mangueira","family":"Saraiva-Romanholo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2020.118912_bb0005","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.iac.2011.07.002","article-title":"Irritant-induced airway disorders","volume":"31","author":"Brooks","year":"2011","journal-title":"Immunol. Allergy Clin. N. Am."},{"key":"10.1016\/j.lfs.2020.118912_bb0010","author":"Lemi\u00e8re"},{"key":"10.1016\/j.lfs.2020.118912_bb0015","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1111\/all.12448","article-title":"EAACI position paper: irritant-induced asthma","volume":"69","author":"Vandenplas","year":"2014","journal-title":"Allergy"},{"key":"10.1016\/j.lfs.2020.118912_bb0020","first-page":"542","article-title":"Cleaning agents and asthma","volume":"20","author":"Quirce","year":"2010","journal-title":"J Investig Allergol Clin Immunol"},{"key":"10.1016\/j.lfs.2020.118912_bb0025","author":"OSHA"},{"key":"10.1016\/j.lfs.2020.118912_bb0030","first-page":"151","article-title":"Chlorine gas: an evolving hazardous material threat and unconventional weapon","volume":"11","author":"Jones","year":"2010","journal-title":"West. J. Emerg. Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0035","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1136\/oem.58.6.399","article-title":"Short term respiratory effects of acute exposure to chlorine due to a swimming pool accident","volume":"58","author":"Agabiti","year":"2001","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0040","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1111\/all.12279","article-title":"Asthma and exposure to cleaning products - a European academy of allergy and clinical immunology task force consensus statement","volume":"68","author":"Siracusa","year":"2013","journal-title":"Allergy"},{"key":"10.1016\/j.lfs.2020.118912_bb0045","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.taap.2009.04.007","article-title":"Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages","volume":"238","author":"Woods","year":"2009","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.lfs.2020.118912_bb0050","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1164\/rccm.200201-021OC","article-title":"Chlorine-induced injury to the airways in mice","volume":"168","author":"Martin","year":"2003","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0055","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s00408-004-2530-3","article-title":"Chlorine: state of the art","volume":"183","author":"Evans","year":"2005","journal-title":"Lung"},{"key":"10.1016\/j.lfs.2020.118912_bb0060","author":"GINA"},{"key":"10.1016\/j.lfs.2020.118912_bb0065","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/all.12347","article-title":"Occupational upper airway disease: how work affects the nose","volume":"69","author":"Hox","year":"2014","journal-title":"Allergy"},{"key":"10.1016\/j.lfs.2020.118912_bb0070","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3109\/02770903.2013.833217","article-title":"Asthma and rhinitis in cleaning workers: a systematic review of epidemiological studies","volume":"51","author":"Folletti","year":"2014","journal-title":"J. Asthma"},{"key":"10.1016\/j.lfs.2020.118912_bb0075","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.yrtph.2017.09.013","article-title":"Cleaning and asthma: a systematic review and approach for effective safety assessment","volume":"90","author":"Vincent","year":"2017","journal-title":"Regulatory Toxicol. Pharmacol."},{"key":"10.1016\/j.lfs.2020.118912_bb0080","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/MCP.0000000000000658","article-title":"Occupational lung diseases in the 21st century: the changing landscape and future challenges","volume":"26","author":"Fazen","year":"2020","journal-title":"Curr. Opin. Pulm. Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0085","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/ACI.0b013e32835143b8","article-title":"Irritant-induced asthma","volume":"12","author":"Labrecque","year":"2012","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"key":"10.1016\/j.lfs.2020.118912_bb0090","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1164\/rccm.200810-1550OC","article-title":"Long-term outcomes of acute irritant-induced asthma","volume":"179","author":"Malo","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0095","doi-asserted-by":"crossref","first-page":"S195","DOI":"10.1097\/01.CCM.0000057843.47705.E8","article-title":"Neutrophils and acute lung injury","volume":"31","author":"Abraham","year":"2003","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0100","doi-asserted-by":"crossref","first-page":"293","DOI":"10.2119\/molmed.2010.00138","article-title":"Contribution of neutrophils to acute lung injury","volume":"17","author":"Grommes","year":"2011","journal-title":"Mol. Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0105","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.rmed.2006.11.003","article-title":"Protein kinase C inhibition attenuates hypochlorite-induced acute lung injury","volume":"101","author":"Hammerschmidt","year":"2007","journal-title":"Respir. Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0110","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1006\/enrs.2000.4110","article-title":"The toxicology of chlorine","volume":"85","author":"Winder","year":"2001","journal-title":"Environ. Res."},{"key":"10.1016\/j.lfs.2020.118912_bb0115","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1513\/pats.201001-009SM","article-title":"Mechanisms and modification of chlorine-induced lung injury in animals","volume":"7","author":"Yadav","year":"2010","journal-title":"Proc. Am. Thorac. Soc."},{"key":"10.1016\/j.lfs.2020.118912_bb0120","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.bbadis.2004.07.003","article-title":"The oxidants hypochlorite and hydrogen peroxide induce distinct patterns of acute lung injury","volume":"1690","author":"Hammerschmidt","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.lfs.2020.118912_bb0125","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s00726-003-0016-x","article-title":"Hypochlorite-induced oxidation of amino acids, peptides and proteins","volume":"25","author":"Hawkins","year":"2003","journal-title":"Amino Acids"},{"key":"10.1016\/j.lfs.2020.118912_bb0130","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1513\/pats.201001-008SM","article-title":"Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models","volume":"7","author":"White","year":"2010","journal-title":"Proc. Am. Thorac. Soc."},{"key":"10.1016\/j.lfs.2020.118912_bb0135","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/nyas.13091","article-title":"Chlorine-induced cardiopulmonary injury","volume":"1374","author":"Carlisle","year":"2016","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.lfs.2020.118912_bb0140","doi-asserted-by":"crossref","first-page":"S159","DOI":"10.33549\/physiolres.933673","article-title":"Physiology of nitric oxide in the respiratory system","volume":"66","author":"Antosova","year":"2017","journal-title":"Physiol. Res."},{"key":"10.1016\/j.lfs.2020.118912_bb0145","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.bbagen.2011.02.002","article-title":"T(H)17 cells in asthma and inflammation","volume":"1810","author":"Aujla","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.lfs.2020.118912_bb0150","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1002\/eji.201646723","article-title":"IL-17 and IL-22 in immunity: driving protection and pathology","volume":"47","author":"Eyerich","year":"2017","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.lfs.2020.118912_bb0155","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.3389\/fphar.2018.01021","article-title":"Protective effects of anti-IL17 on acute lung injury induced by LPS in mice","volume":"9","author":"Righetti","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.lfs.2020.118912_bb0160","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.3389\/fimmu.2017.01835","article-title":"Effects of anti-IL-17 on inflammation, remodeling, and oxidative stress in an experimental model of asthma exacerbated by LPS","volume":"8","author":"Camargo","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.lfs.2020.118912_bb0165","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.3389\/fphys.2018.01183","article-title":"Effect of anti-IL17 antibody treatment alone and in combination with rho-kinase inhibitor in a murine model of asthma","volume":"9","author":"Dos Santos","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.lfs.2020.118912_bb0170","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1165\/rcmb.2010-0226OC","article-title":"Postexposure administration of a {beta}2-agonist decreases chlorine-induced airway hyperreactivity in mice","volume":"45","author":"Song","year":"2011","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.lfs.2020.118912_bb0175","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1165\/rcmb.2013-0430OC","article-title":"Neutrophils mediate airway hyperresponsiveness after chlorine-induced airway injury in the mouse","volume":"52","author":"McGovern","year":"2015","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.lfs.2020.118912_bb0180","article-title":"Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice","volume":"8","author":"de Genaro","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2020.118912_bb0185","first-page":"33","article-title":"European Parliament and the Council of European Union - directive 2010\/63\/EU - European Parliament and of the council of 22 September 2010 on the protection of animals used for scientific purposes","volume":"53","author":"European-Union","year":"2010","journal-title":"Off. J. Eur. Union"},{"key":"10.1016\/j.lfs.2020.118912_bb0190","series-title":"Neutron Activation Analysis","author":"De Soete","year":"1972"},{"key":"10.1016\/j.lfs.2020.118912_bb0195","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1083\/jcb.30.1.23","article-title":"Practical stereological methods for morphometric cytology","volume":"30","author":"Weibel","year":"1966","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.lfs.2020.118912_bb0200","first-page":"41","article-title":"Secretory cell hyperplasia and modification of intracellular glycoprotein in rat airways induced by short periods of exposure to tobacco smoke, and the effect of the antiinflammatory agent phenylmethyloxadiazole","volume":"39","author":"Jones","year":"1978","journal-title":"Laboratory Invest."},{"key":"10.1016\/j.lfs.2020.118912_bb0205","unstructured":"R.A. Herbert and J.R. Leininger, Nose, larynx and trachea, in Pathology of the Mouse: Reference and Atlas, R.R. Maronpot, Editor. 1999. p. 259\u2013292."},{"key":"10.1016\/j.lfs.2020.118912_bb0210","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.envres.2005.12.018","article-title":"Effects of Sao Paulo air pollution on the upper airways of mice","volume":"101","author":"Camargo Pires-Neto","year":"2006","journal-title":"Environ. Res."},{"key":"10.1016\/j.lfs.2020.118912_bb0215","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1093\/toxsci\/kfi038","article-title":"Acute respiratory responses of the mouse to chlorine","volume":"83","author":"Morris","year":"2005","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.lfs.2020.118912_bb0220","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1183\/09031936.98.11040922","article-title":"Time-course of functional and pathological changes after a single high acute inhalation of chlorine in rats","volume":"11","author":"Demnati","year":"1998","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.lfs.2020.118912_bb0225","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.rmed.2016.06.019","article-title":"Women using bleach for home cleaning are at increased risk of non-allergic asthma","volume":"117","author":"Matulonga","year":"2016","journal-title":"Respir. Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0230","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/ajim.22244","article-title":"Cleaning and asthma characteristics in women","volume":"57","author":"Dumas","year":"2014","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0235","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1164\/rccm.201208-1358OC","article-title":"Crucial role of transient receptor potential ankyrin 1 and mast cells in induction of nonallergic airway hyperreactivity in mice","volume":"187","author":"Hox","year":"2013","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.lfs.2020.118912_bb0240","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.1172\/JCI34192","article-title":"TRPA1 is a major oxidant sensor in murine airway sensory neurons","volume":"118","author":"Bessac","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.lfs.2020.118912_bb0245","doi-asserted-by":"crossref","DOI":"10.1186\/1465-9921-9-61","article-title":"Time course of airway remodelling after an acute chlorine gas exposure in mice","volume":"9","author":"Tuck","year":"2008","journal-title":"Respir. Res."},{"key":"10.1016\/j.lfs.2020.118912_bb0250","doi-asserted-by":"crossref","DOI":"10.1186\/1465-9921-9-51","article-title":"Changes in the mechanical properties of the respiratory system during the development of interstitial lung edema","volume":"9","author":"Dellaca","year":"2008","journal-title":"Respir. Res."},{"key":"10.1016\/j.lfs.2020.118912_bb0255","article-title":"Chronic low dose chlorine exposure aggravates allergic inflammation and airway hyperresponsiveness and activates inflammasome pathway","volume":"9","author":"Kim","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2020.118912_bb0260","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.resp.2012.03.005","article-title":"Cigarette smoke dissociates inflammation and lung remodeling in OVA-sensitized and challenged mice","volume":"181","author":"Hizume","year":"2012","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.lfs.2020.118912_bb0265","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1378\/chest.112.1.45","article-title":"Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine","volume":"112","author":"Boulet","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.lfs.2020.118912_bb0270","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1080\/08958370490520749","article-title":"Long-term pulmonary histopathologic changes in rats following acute experimental exposure to chlorine gas","volume":"16","author":"Yildirim","year":"2004","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.lfs.2020.118912_bb0275","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.it.2015.01.005","article-title":"Lung ILC2s link innate and adaptive responses in allergic inflammation","volume":"36","author":"Martinez-Gonzalez","year":"2015","journal-title":"Trends Immunol."},{"key":"10.1016\/j.lfs.2020.118912_bb0280","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1146\/annurev.immunol.21.120601.141142","article-title":"IL-13 effector functions","volume":"21","author":"Wynn","year":"2003","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.lfs.2020.118912_bb0285","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.molimm.2017.01.014","article-title":"Inflammasomes in the lung","volume":"86","author":"Pinkerton","year":"2017","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.lfs.2020.118912_bb0290","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4103\/0975-3583.59983","article-title":"The dual role of TNF in pulmonary edema","volume":"1","author":"Yang","year":"2010","journal-title":"J. Cardiovasc. Dis. Res."},{"key":"10.1016\/j.lfs.2020.118912_bb0295","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.3389\/fimmu.2017.01644","article-title":"Cytokine-ion channel interactions in pulmonary inflammation","volume":"8","author":"Hamacher","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.lfs.2020.118912_bb0300","doi-asserted-by":"crossref","DOI":"10.1007\/s11882-017-0735-9","article-title":"Role of type 2 innate lymphoid cells in allergic diseases","volume":"17","author":"Cosmi","year":"2017","journal-title":"Curr Allergy Asthma Rep"},{"key":"10.1016\/j.lfs.2020.118912_bb0305","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1939-4551-7-32","article-title":"Anti-IL5 therapy for asthma and beyond","volume":"7","author":"Mukherjee","year":"2014","journal-title":"World Allergy Organization J."},{"key":"10.1016\/j.lfs.2020.118912_bb0310","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.coph.2013.03.013","article-title":"Cytokine targets in airway inflammation","volume":"13","author":"Schuijs","year":"2013","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.lfs.2020.118912_bb0315","article-title":"Aggravation of asthmatic inflammation by chlorine exposure via innate lymphoid cells and CD11c(intermediate) macrophages","author":"Shim","year":"2019","journal-title":"Allergy"},{"key":"10.1016\/j.lfs.2020.118912_bb0320","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1165\/rcmb.2010-0151OC","article-title":"Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling","volume":"45","author":"Honavar","year":"2011","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.lfs.2020.118912_bb0325","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.resp.2013.12.012","article-title":"Effects of rho-kinase inhibition in lung tissue with chronic inflammation","volume":"192","author":"Righetti","year":"2014","journal-title":"Respir. Physiol. Neurobiol."},{"key":"10.1016\/j.lfs.2020.118912_bb0330","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.taap.2013.04.037","article-title":"Early treatment of chlorine-induced airway hyperresponsiveness and inflammation with corticosteroids","volume":"271","author":"Jonasson","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320520316714?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320520316714?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T03:23:22Z","timestamp":1719890602000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320520316714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":66,"alternative-id":["S0024320520316714"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2020.118912","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low-dose chlorine exposure impairs lung function, inflammation and oxidative stress in mice","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2020.118912","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"118912"}}