{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T20:35:17Z","timestamp":1792874117554,"version":"4.5.0"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["308964\/2019-5"],"award-info":[{"award-number":["308964\/2019-5"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["306631\/2018-0"],"award-info":[{"award-number":["306631\/2018-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2019\/05242-9"],"award-info":[{"award-number":["2019\/05242-9"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2020\/16020-4"],"award-info":[{"award-number":["2020\/16020-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2019\/11490-5"],"award-info":[{"award-number":["2019\/11490-5"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2017\/02042-3"],"award-info":[{"award-number":["2017\/02042-3"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.lfs.2021.119764","type":"journal-article","created":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T10:48:25Z","timestamp":1624704505000},"page":"119764","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Intrauterine growth restriction leads to a high-corticosterone producing offspring: An implication for pulmonary infection susceptibility"],"prefix":"10.1016","volume":"281","author":[{"given":"Noemi L.","family":"Gil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela A.","family":"Azevedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandro M.","family":"Balbino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina M.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Helena C.","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana H.","family":"Akamine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre C.","family":"Keller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richardt G.","family":"Landgraf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maristella A.","family":"Landgraf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6761","key":"10.1016\/j.lfs.2021.119764_bb0005","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1136\/bmj.301.6761.1111","article-title":"The fetal and infant origins of adult disease","volume":"301","author":"Barker","year":"1990","journal-title":"Br. Med. J."},{"key":"10.1016\/j.lfs.2021.119764_bb0010","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.reprotox.2005.04.007","article-title":"Intrauterine growth restriction-etiology and consequences: what do we know about the human situation and experimental animal models?","volume":"3","author":"Ergaz","year":"2005","journal-title":"Reprod. Toxicol."},{"issue":"3","key":"10.1016\/j.lfs.2021.119764_bb0015","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s12079-012-0165-3","article-title":"Molecular mechanisms underlying the fetal programming of adult disease","volume":"6","author":"Vo","year":"2012","journal-title":"J. Cell. Commun. Signal."},{"key":"10.1016\/j.lfs.2021.119764_bb0020","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4137\/CMPed.S40070","article-title":"Intrauterine growth restriction: antenatal and postnatal aspects","volume":"10","author":"Sharma","year":"2016","journal-title":"Clin. Med. Insights Pediatr."},{"issue":"5","key":"10.1016\/j.lfs.2021.119764_bb0025","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1093\/ajcn\/85.5.1244","article-title":"Is birth weight a risk factor for ischemic heart disease in later life?","volume":"85","author":"Huxley","year":"2007","journal-title":"Am. J. Clin. Nutr."},{"issue":"5","key":"10.1016\/j.lfs.2021.119764_bb0030","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1210\/me.2010-0395","article-title":"Maternal protein restriction elevates cholesterol in adult rat offspring due to repressive changes in histone modifications at the cholesterol 7alpha-hydroxylase promoter","volume":"25","author":"Sohi","year":"2011","journal-title":"Mol. Endocrinol."},{"issue":"6","key":"10.1016\/j.lfs.2021.119764_bb0035","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1017\/S2040174417000484","article-title":"Intrauterine growth restriction-induced deleterious adaptations in endothelial progenitor cells: possible mechanism to impair endothelial function","volume":"8","author":"Oliveira","year":"2017","journal-title":"J. Dev. Orig. Health Dis."},{"key":"10.1016\/j.lfs.2021.119764_bb0040","first-page":"3821409","article-title":"Prenatal malnutrition-induced epigenetic dysregulation as a risk factor for type 2 diabetes","author":"Vaiserman","year":"2019","journal-title":"Int. J. Genomics."},{"issue":"1","key":"10.1016\/j.lfs.2021.119764_bb0045","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1465-9921-12-5","article-title":"Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis","volume":"12","author":"Jones","year":"2011","journal-title":"Respir. Res."},{"key":"10.1016\/j.lfs.2021.119764_bb0050","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1093\/aje\/kwm134","article-title":"Effects of pre- and postnatal exposure to parental smoking on early childhood respiratory health","volume":"166","author":"H\u00e5berg","year":"2007","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.lfs.2021.119764_bb0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000374","article-title":"Association of secondhand smoke exposure with pediatric invasive bacterial disease and bacterial carriage: a systematic review and meta-analysis","volume":"7","author":"Lee","year":"2010","journal-title":"PLoS Med."},{"issue":"6","key":"10.1016\/j.lfs.2021.119764_bb0060","first-page":"3101","article-title":"Maternal protein restriction alters VEGF signaling and decreases pulmonary alveolar in fetal rats","volume":"7","author":"Liu","year":"2014","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"12","key":"10.1016\/j.lfs.2021.119764_bb0065","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1136\/thorax.58.12.1061","article-title":"Relationship between birth weight and adult lung function: controlling for maternal factors","volume":"58","author":"Edwards","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.lfs.2021.119764_bb0070","series-title":"The Childhood Environment and Adult Disease, Ciba Foundation Symposium","first-page":"77","article-title":"Interactions between early nutrition and the immune system","volume":"156","author":"Chandra","year":"1991"},{"issue":"3","key":"10.1016\/j.lfs.2021.119764_bb0075","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1086\/650313","article-title":"Evidence for an effect of fetal growth on the risk of tuberculosis","volume":"201","author":"Villamor","year":"2010","journal-title":"J. Infect. Dis."},{"issue":"2","key":"10.1016\/j.lfs.2021.119764_bb0080","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1530\/JOE-14-0537","article-title":"Impaired miR449a-induced downregulation of Crhr1 expression in low-birth-weight rats","volume":"224","author":"Nemoto","year":"2015","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.lfs.2021.119764_bb0085","doi-asserted-by":"crossref","first-page":"136","DOI":"10.3389\/fimmu.2014.00136","article-title":"The HPA - immune axis and the immunomodulatory actions of glucocorticoids in the brain","volume":"5","author":"Bellavance","year":"2014","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.lfs.2021.119764_bb0090","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1001341","article-title":"The origin of glucocorticoid hormone oscillations","volume":"10","author":"Walker","year":"2012","journal-title":"PLoS Biol."},{"issue":"7","key":"10.1016\/j.lfs.2021.119764_bb0095","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1210\/en.2016-1123","article-title":"Glucocorticoid fast feedback inhibition of stress-induced ACTH secretion in the male rat: rate independence and stress-state resistance","volume":"157","author":"Osterlund","year":"2016","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.lfs.2021.119764_bb0100","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1093\/jn\/135.6.1480","article-title":"Intrauterine undernutrition in rats interferes with leukocyte migration, decreasing adhesion molecule expression in leukocytes and endothelial cells","volume":"135","author":"Landgraf","year":"2005","journal-title":"J. Nutr."},{"issue":"3","key":"10.1016\/j.lfs.2021.119764_bb0105","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.nut.2007.12.005","article-title":"Influence of age on the development of immunological lung response in intrauterine undernourishment","volume":"24","author":"Landgraf","year":"2008","journal-title":"Nutrition"},{"issue":"3","key":"10.1016\/j.lfs.2021.119764_bb0110","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1159\/000341437","article-title":"Intrauterine undernourishment alters TH1\/TH2 cytokine balance and attenuates lung allergic inflammation in wistar rats","volume":"30","author":"Landgraf","year":"2012","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.lfs.2021.119764_bb0115","doi-asserted-by":"crossref","first-page":"2836","DOI":"10.1038\/s41598-019-39349-1","article-title":"Protective effect of oxytocin on LPS-induced acute lung injury in mice","volume":"9","author":"An","year":"2019","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.lfs.2021.119764_bb0120","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.smim.2003.10.003","article-title":"TLR signaling pathways","volume":"16","author":"Takeda","year":"2004","journal-title":"Semin. Immunol."},{"issue":"5","key":"10.1016\/j.lfs.2021.119764_bb0125","doi-asserted-by":"crossref","first-page":"4505","DOI":"10.3892\/mmr.2016.5825","article-title":"NF-?B inhibition attenuates LPS-induced TLR4 activation in monocyte cells","volume":"14","author":"Wan","year":"2016","journal-title":"Mol. Med. Rep."},{"issue":"8","key":"10.1016\/j.lfs.2021.119764_bb0130","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.bbadis.2010.12.023","article-title":"Sex differences in nuclear receptor-regulated liver metabolic pathways","volume":"1812","author":"Rando","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.lfs.2021.119764_bb0135","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.lfs.2005.05.057","article-title":"Role of insulin on PGE2 generation during LPS-induced lung inflammation in rats","volume":"78","author":"Alba-Loureiro","year":"2006","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.lfs.2021.119764_bb0140","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/SHK.0b013e3181a85ec4","article-title":"Signaling pathways and mediators in LPS-induced lung inflammation in diabetic rats: role of insulin","volume":"33","author":"Martins","year":"2010","journal-title":"Shock"},{"issue":"10","key":"10.1016\/j.lfs.2021.119764_bb0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0076786","article-title":"Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice","volume":"8","author":"Calixto","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.lfs.2021.119764_bb0150","article-title":"Intrauterine malnutrition reduced long leptin receptor isoform expression and proinflammatory cytokine production in male rat pulmonary endothelial cells stimulated by lipopolysaccharide","volume":"8597361","author":"Balbino","year":"2018","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.lfs.2021.119764_bb0155","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.toxicon.2017.11.005","article-title":"A comparative study of pathophysiological alterations in scorpionism induced by Tityus serrulatus and Tityus bahiensis venoms","volume":"141","author":"Miyamoto","year":"2018","journal-title":"Toxicon"},{"key":"10.1016\/j.lfs.2021.119764_bb0160","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1159\/000358656","article-title":"Leptin downregulates LPS-induced lung","volume":"33","author":"Landgraf","year":"2014","journal-title":"Cell. Physiol. Biochem."},{"issue":"7","key":"10.1016\/j.lfs.2021.119764_bb0165","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1021\/ac00284a003","article-title":"Enzyme immunoassays of eicosanoids using acetylcholinesterase as label: an alternative to radioimmunoassay","volume":"57","author":"Pradelles","year":"1985","journal-title":"Anal. Chem."},{"issue":"3\u20134","key":"10.1016\/j.lfs.2021.119764_bb0170","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.plefa.2007.08.011","article-title":"Prostaglandins, leukotrienes and PAF selectively modulate lymphocyte subset and eosinophil infiltration into the airways in a murine model of asthma","volume":"77","author":"Landgraf","year":"2007","journal-title":"Prostaglandins Leukot. Essent. Fat. Acids"},{"issue":"4","key":"10.1016\/j.lfs.2021.119764_bb0175","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"issue":"1","key":"10.1016\/j.lfs.2021.119764_bb0180","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/1440-1681.12505","article-title":"The role of maternal nutrition, metabolic function and the placenta in developmental programming of renal dysfunction","volume":"43","author":"Richter","year":"2016","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"issue":"5","key":"10.1016\/j.lfs.2021.119764_bb0185","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00418-017-1587-z","article-title":"Experimentally induced Intrauterine growth restriction in rabbits leads to differential remodelling of left versus right ventricular myocardial microstructure","volume":"148","author":"Schipke","year":"2017","journal-title":"Histochem. Cell Biol."},{"issue":"5","key":"10.1016\/j.lfs.2021.119764_bb0190","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1165\/rcmb.2009-0210ST","article-title":"An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals","volume":"44","author":"Matute-Bello","year":"2011","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"9","key":"10.1016\/j.lfs.2021.119764_bb0195","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3389\/fphar.2018.00142","article-title":"Downregulation of TLR4 by miR-181a provides negative feedback regulation to lipopolysaccharide-induced inflammation","volume":"26","author":"Jiang","year":"2018","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.lfs.2021.119764_bb0200","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.nut.2006.08.020","article-title":"Mechanisms involved in the reduced leukocyte migration in intrauterine undernourishment","volume":"23","author":"Landgraf","year":"2007","journal-title":"Nutrition"},{"issue":"12","key":"10.1016\/j.lfs.2021.119764_bb0205","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1007\/s00011-004-1308-7","article-title":"Evidence that arachidonic acid derived from neutrophils and prostaglandin E2 are associated with the induction of acute lung inflammation by lipopolysaccharide of Escherichia coli","volume":"53","author":"Alba-Loureiro","year":"2004","journal-title":"Inflamm. Res."},{"issue":"4","key":"10.1016\/j.lfs.2021.119764_bb0210","article-title":"Silibinin treatment prevents endotoxin-induced uveitis in rats in vivo and in vitro","volume":"12","author":"Chen","year":"2017","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.lfs.2021.119764_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0181191","article-title":"4&apos;-Hydroxywogonin suppresses lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages and acute lung injury mice","volume":"12","author":"Fan","year":"2017","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.lfs.2021.119764_bb0220","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1084\/jem.187.4.517","article-title":"Compensatory prostaglandin E2 biosynthesis in cyclooxygenase 1 or 2 null cells","volume":"187","author":"Kirtikara","year":"1998","journal-title":"J. Exp. Med."},{"issue":"2","key":"10.1016\/j.lfs.2021.119764_bb0225","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1086\/675991","article-title":"Pleiotropic effects of interleukin-6 in a \"two-hit\" murine model of acute respiratory distress syndrome","volume":"4","author":"Goldman","year":"2014","journal-title":"Pulm. Circ."},{"issue":"1","key":"10.1016\/j.lfs.2021.119764_bb0230","doi-asserted-by":"crossref","first-page":"14676","DOI":"10.1038\/s41598-018-33101-x","article-title":"Hydrogen sulfide limits neutrophil transmigration, inflammation, and oxidative burst in lipopolysaccharide-induced acute lung injury","volume":"8","author":"Faller","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2021.119764_bb0235","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.3389\/fimmu.2020.02091","article-title":"Macrophage TLR4 and PAR2 signaling: role in regulating vascular inflammatory injury and repair","volume":"11","author":"Rayees","year":"2021","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.lfs.2021.119764_bb0240","first-page":"3","article-title":"Endotoxin and the hypothalamo-pituitary-adrenal (HPA) axis","volume":"9","author":"Beishuizen","year":"2003","journal-title":"J. Endotoxin Res."},{"key":"10.1016\/j.lfs.2021.119764_bb0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.compbiomed.2015.09.018","article-title":"Dynamics of the HPA axis and inflammatory cytokines: insights from mathematical modeling","volume":"67","author":"Malek","year":"2015","journal-title":"Comput. Biol. Med."},{"issue":"1","key":"10.1016\/j.lfs.2021.119764_bb0250","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.bbrc.2018.12.101","article-title":"The pituitary gland prevents shock-associated death by controlling multiple inflammatory mediators","volume":"509","author":"Sharma","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.lfs.2021.119764_bb0255","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.6368","article-title":"Intrauterine growth and the maturation process of adrenal function","volume":"7","author":"Iwata","year":"2019","journal-title":"PeerJ"},{"issue":"2","key":"10.1016\/j.lfs.2021.119764_bb0260","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.jss.2010.10.016","article-title":"Major stress hormones suppress the response of macrophages through down-regulation of TLR2 and TLR4","volume":"173","author":"Du","year":"2012","journal-title":"J. Surg. Res."},{"issue":"3","key":"10.1016\/j.lfs.2021.119764_bb0265","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1152\/physrev.00020.2012","article-title":"11\u00df-Hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action","volume":"93","author":"Chapman","year":"2013","journal-title":"Physiol. Rev."},{"issue":"1","key":"10.1016\/j.lfs.2021.119764_bb0270","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1210\/en.2011-1398","article-title":"11\u00df-Hydroxysteroid dehydrogenase type 1, but not type 2, deficiency worsens acute inflammation and experimental arthritis in mice","volume":"153","author":"Coutinho","year":"2012","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.lfs.2021.119764_bb0275","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000204227","article-title":"11beta-hydroxysteroid dehydrogenases are regulated during the pulmonary granulomatous response to the mycobacterial glycolipid trehalose-6,6\u2019-dimycolate","volume":"16","author":"Abbott","year":"2009","journal-title":"Neuroimmunomodulation"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320521007505?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320521007505?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:44:05Z","timestamp":1777423445000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320521007505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":55,"alternative-id":["S0024320521007505"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2021.119764","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intrauterine growth restriction leads to a high-corticosterone producing offspring: An implication for pulmonary infection susceptibility","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2021.119764","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"119764"}}