{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T17:03:46Z","timestamp":1779296626000,"version":"3.51.4"},"reference-count":91,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000921","name":"European Cooperation in Science and Technology","doi-asserted-by":"publisher","award":["CA15138"],"award-info":[{"award-number":["CA15138"]}],"id":[{"id":"10.13039\/501100000921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Ministarstvo Prosvete, Nauke i Tehnolo\u0161kog Razvoja","doi-asserted-by":"publisher","award":["451-03-68\/2022-14\/200007"],"award-info":[{"award-number":["451-03-68\/2022-14\/200007"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Ministarstvo Prosvete, Nauke i Tehnolo\u0161kog Razvoja","doi-asserted-by":"publisher","award":["451-03-68\/2022-14\/200110"],"award-info":[{"award-number":["451-03-68\/2022-14\/200110"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.lfs.2022.120481","type":"journal-article","created":{"date-parts":[[2022,3,15]],"date-time":"2022-03-15T03:11:49Z","timestamp":1647313909000},"page":"120481","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["MAP kinase-dependent autophagy controls phorbol myristate acetate-induced macrophage differentiation of HL-60 leukemia cells"],"prefix":"10.1016","volume":"297","author":[{"given":"Milos","family":"Mandic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Misirkic Marjanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ljubica","family":"Vucicevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Jovanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihajlo","family":"Bosnjak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Perovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biljana","family":"Ristic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darko","family":"Ciric","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ljubica","family":"Harhaji-Trajkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8061-2968","authenticated-orcid":false,"given":"Vladimir","family":"Trajkovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2022.120481_bb0005","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/S0140-6736(12)61727-9","article-title":"Acute myeloid leukaemia in adults","volume":"381","author":"Ferrara","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.lfs.2022.120481_bb0010","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.biotechadv.2015.03.013","article-title":"Natural compounds and pharmaceuticals reprogram leukemia cell differentiation pathways","volume":"33","author":"Morceau","year":"2015","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.lfs.2022.120481_bb0015","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1073\/pnas.76.6.2779","article-title":"Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester","volume":"76","author":"Rovera","year":"1979","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.lfs.2022.120481_bb0020","doi-asserted-by":"crossref","first-page":"2936","DOI":"10.1073\/pnas.77.5.2936","article-title":"Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid","volume":"77","author":"Breitman","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.lfs.2022.120481_bb0025","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/0006-291X(81)91628-4","article-title":"1 alpha,25-dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells","volume":"102","author":"Miyaura","year":"1981","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.lfs.2022.120481_bb0030","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/nrc2110","article-title":"Protein kinase C and other diacylglycerol effectors in cancer","volume":"7","author":"Griner","year":"2007","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.lfs.2022.120481_bb0035","doi-asserted-by":"crossref","first-page":"4327","DOI":"10.1016\/S0021-9258(17)41782-0","article-title":"Activation of \u03b2-isozyme of protein kinase C (PKC\u03b2) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes. Studies with PKC\u03b2-defective PET mutant","volume":"269","author":"Macfarlane","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2022.120481_bb0040","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1128\/MCB.19.1.461","article-title":"Functional role for protein kinase C\u03b2 as a regulator of stress-activated protein kinase activation and monocytic differentiation of myeloid leukemia cells","volume":"19","author":"Kaneki","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0045","doi-asserted-by":"crossref","first-page":"23230","DOI":"10.1016\/S0021-9258(17)31643-5","article-title":"Protein kinase C-\u03b2 is required for macrophage differentiation of human HL-60 leukemia cells","volume":"269","author":"Tonetti","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2022.120481_bb0050","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1080\/10409238.2018.1442408","article-title":"Protein kinase C: perfectly balanced","volume":"53","author":"Newton","year":"2018","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0055","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s13238-016-0261-x","article-title":"Phorbol myristate acetate suppresses breast cancer cell growth via down-regulation of P-Rex1 expression","volume":"7","author":"Wong","year":"2016","journal-title":"Protein Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0060","doi-asserted-by":"crossref","first-page":"44940","DOI":"10.1038\/srep44940","article-title":"12-O-Tetradecanoylphorbol-13-acetate (TPA) is anti-tumorigenic in liver cancer cells via inhibiting YAP through AMOT","volume":"7","author":"Zhu","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2022.120481_bb0065","doi-asserted-by":"crossref","first-page":"9424","DOI":"10.1074\/jbc.272.14.9424","article-title":"Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1\/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells","volume":"272","author":"Frey","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2022.120481_bb0070","doi-asserted-by":"crossref","DOI":"10.4172\/2329-6917.1000168","article-title":"12-O-Tetradecanoylphorbol-13-acetate for refractory secondary acute myeloid leukemia","volume":"3","author":"Baijun Fang","year":"2015","journal-title":"J. Leukemia"},{"key":"10.1016\/j.lfs.2022.120481_bb0075","doi-asserted-by":"crossref","first-page":"5357","DOI":"10.1073\/pnas.95.9.5357","article-title":"Effect of intravenous infusions of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: preliminary studies on therapeutic efficacy and toxicity","volume":"95","author":"Han","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.lfs.2022.120481_bb0080","first-page":"2512","article-title":"Administration of a phorbol ester to patients with hematological malignancies: preliminary results from a phase I clinical trial of 12-O-tetradecanoylphorbol-13-acetate","volume":"8","author":"Strair","year":"2002","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.lfs.2022.120481_bb0085","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.leukres.2005.04.015","article-title":"12-O-Tetradecanoylphorbol-13-acetate in acute myeloid leukemia","volume":"29","author":"Chan","year":"2005","journal-title":"Leuk. Res."},{"key":"10.1016\/j.lfs.2022.120481_bb0090","doi-asserted-by":"crossref","first-page":"588","DOI":"10.15698\/mic2016.12.546","article-title":"Autophagy: machinery and regulation","volume":"3","author":"Yin","year":"2016","journal-title":"Microb. Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0095","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.molcel.2010.09.023","article-title":"Autophagy and the integrated stress response","volume":"40","author":"Kroemer","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0100","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/ncb0910-823","article-title":"Autophagy in mammalian development and differentiation","volume":"12","author":"Mizushima","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0105","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.4161\/auto.5.8.9889","article-title":"Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line","volume":"5","author":"Colosetti","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0110","doi-asserted-by":"crossref","first-page":"34413","DOI":"10.1038\/srep34413","article-title":"Photodynamic N-TiO2 nanoparticle treatment induces controlled ROS-mediated autophagy and terminal differentiation of leukemia cells","volume":"6","author":"Moosavi","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2022.120481_bb0115","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1111\/febs.13962","article-title":"Mechanistic roles of autophagy in hematopoietic differentiation","volume":"284","author":"Riffelmacher","year":"2017","journal-title":"FEBS J."},{"key":"10.1016\/j.lfs.2022.120481_bb0120","doi-asserted-by":"crossref","first-page":"401","DOI":"10.4161\/auto.7.4.14397","article-title":"Autophagy regulates myeloid cell differentiation by p62\/SQSTM1-mediated degradation of PML-RAR\u03b1 oncoprotein","volume":"7","author":"Wang","year":"2011","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0125","doi-asserted-by":"crossref","first-page":"16100","DOI":"10.1039\/C5NR04200C","article-title":"Silver nanoparticles impede phorbol myristate acetate-induced monocyte-macrophage differentiation and autophagy","volume":"7","author":"Xu","year":"2015","journal-title":"Nanoscale"},{"key":"10.1016\/j.lfs.2022.120481_bb0130","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.tcb.2015.02.002","article-title":"How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy","volume":"25","author":"Feng","year":"2015","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0135","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1042\/EBC20170027","article-title":"mTORC1 as the main gateway to autophagy","volume":"61","author":"Rabanal-Ruiz","year":"2017","journal-title":"Essays Biochem."},{"key":"10.1016\/j.lfs.2022.120481_bb0140","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20140141","article-title":"MAPK\/JNK signalling: a potential autophagy regulation pathway","volume":"35","author":"Zhou","year":"2015","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.lfs.2022.120481_bb0145","doi-asserted-by":"crossref","first-page":"4984","DOI":"10.1016\/j.febslet.2006.08.025","article-title":"Functions of the MAPK family in vertebrate-development","volume":"580","author":"Krens","year":"2006","journal-title":"FEBS Lett."},{"key":"10.1016\/j.lfs.2022.120481_bb0150","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.canlet.2013.11.019","article-title":"p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents","volume":"344","author":"Sui","year":"2014","journal-title":"Cancer Lett."},{"key":"10.1016\/j.lfs.2022.120481_bb0155","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1742-4658.2009.07366.x","article-title":"ERK and cell death: mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence","volume":"277","author":"Cagnol","year":"2010","journal-title":"FEBS J."},{"key":"10.1016\/j.lfs.2022.120481_bb0160","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.yexcr.2014.08.001","article-title":"Raf\/MEK\/ERK can regulate cellular levels of LC3B and SQSTM1\/p62 at expression levels","volume":"327","author":"Kim","year":"2014","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.lfs.2022.120481_bb0165","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.molcel.2013.01.024","article-title":"ZKSCAN3 is a master transcriptional repressor of autophagy","volume":"50","author":"Chauhan","year":"2013","journal-title":"Mol. Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0170","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1038\/ncb3407","article-title":"Protein kinase C controls lysosome biogenesis independently of mTORC1","volume":"18","author":"Li","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0175","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1126\/science.1204592","article-title":"TFEB links autophagy to lysosomal biogenesis","volume":"332","author":"Settembre","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.lfs.2022.120481_bb0180","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.leukres.2018.03.012","article-title":"Reactive oxygen species activate differentiation gene transcription of acute myeloid leukemia cells via the JNK\/c-JUN signaling pathway","volume":"68","author":"Lam","year":"2018","journal-title":"Leuk. Res."},{"key":"10.1016\/j.lfs.2022.120481_bb0185","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1038\/sj.leu.2402400","article-title":"Importance of MEK-1\/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines","volume":"16","author":"Miranda","year":"2002","journal-title":"Leukemia"},{"key":"10.1016\/j.lfs.2022.120481_bb0190","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.biocel.2004.05.021","article-title":"Magnolol and honokiol enhance HL-60 human leukemia cell differentiation induced by 1,25-dihydroxyvitamin D3 and retinoic acid","volume":"37","author":"Fong","year":"2005","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0195","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.3892\/ijo.2013.2106","article-title":"Involvement of histone H3 phosphorylation through p38 MAPK pathway activation in casticin-induced cytocidal effects against the human promyelocytic cell line HL-60","volume":"43","author":"Kikuchi","year":"2013","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.lfs.2022.120481_bb0200","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s11010-017-3259-7","article-title":"GDC-0152-induced autophagy promotes apoptosis in HL-60 cells","volume":"445","author":"Peiqi","year":"2018","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.lfs.2022.120481_bb0205","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1016\/j.cellsig.2007.01.006","article-title":"Protein kinase C\u03b1 mediates feedback inhibition of EGF receptor transactivation induced by gq-coupled receptor agonists","volume":"19","author":"Santiskulvong","year":"2007","journal-title":"Cell. Signal."},{"key":"10.1016\/j.lfs.2022.120481_bb0210","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1111\/jcmm.13049","article-title":"Matrine induces Akt\/mTOR signalling inhibition-mediated autophagy and apoptosis in acute myeloid leukaemia cells","volume":"21","author":"Wu","year":"2017","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.lfs.2022.120481_bb0215","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/ijc.21080","article-title":"Novel platinum(IV) complexes induce rapid tumor cell death in vitro","volume":"116","author":"Kaludjerovi\u0107","year":"2005","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.lfs.2022.120481_bb0220","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.biocel.2012.12.017","article-title":"p130Cas acts as survival factor during PMA-induced apoptosis in HL-60 promyelocytic leukemia cells","volume":"45","author":"Kumbrink","year":"2013","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0225","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0960-0760(98)00041-7","article-title":"Expression of vitamin D receptor (VDR) in HL-60 cells is differentially regulated during the process of differentiation induced by phorbol ester, retinoic acid or interferon-gamma","volume":"66","author":"Folgueira","year":"1998","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0230","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/cyto.b.21280","article-title":"Monocytes and macrophages in flow: an ESCCA initiative on advanced analyses of monocyte lineage using flow cytometry","volume":"92","author":"Lambert","year":"2017","journal-title":"Cytometry B Clin. Cytom."},{"key":"10.1016\/j.lfs.2022.120481_bb0235","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0092-8674(93)90660-I","article-title":"The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage","volume":"72","author":"Nguyen","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0240","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/(SICI)1098-2795(199701)46:1<4::AID-MRD2>3.0.CO;2-V","article-title":"Biology and action of colony-stimulating factor-1","volume":"46","author":"Stanley","year":"1997","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.lfs.2022.120481_bb0245","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/0145-2126(94)00151-Y","article-title":"The induction kinetics of IL-8 messenger RNA in HL60 cells demonstrate the participation of negative-acting gene(s)","volume":"19","author":"Meier","year":"1995","journal-title":"Leuk. Res."},{"key":"10.1016\/j.lfs.2022.120481_bb0250","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1083\/jcb.200507002","article-title":"p62\/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death","volume":"171","author":"Bj\u00f8rk\u00f8y","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0255","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1083\/jcb.200412022","article-title":"Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice","volume":"169","author":"Komatsu","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0260","doi-asserted-by":"crossref","first-page":"46","DOI":"10.4161\/auto.1.1.1542","article-title":"The evolutionarily conserved domain of beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function","volume":"1","author":"Furuya","year":"2005","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0265","doi-asserted-by":"crossref","first-page":"585","DOI":"10.4161\/auto.5.5.8823","article-title":"In search of an \"autophagomometer\"","volume":"5","author":"Rubinsztein","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15548627.2015.1100356","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)","volume":"12","author":"Klionsky","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0275","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/s41580-020-0241-0","article-title":"Mechanisms governing autophagosome biogenesis","volume":"21","author":"Nakatogawa","year":"2020","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0280","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/sj.onc.1210678","article-title":"Effects of protein phosphorylation on ubiquitination and stability of the translational inhibitor protein 4E-BP1","volume":"27","author":"Elia","year":"2008","journal-title":"Oncogene"},{"key":"10.1016\/j.lfs.2022.120481_bb0285","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.cell.2005.07.002","article-title":"Bcl-2 antiapoptotic proteins inhibit beclin 1-dependent autophagy","volume":"122","author":"Pattingre","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0290","article-title":"Full-coverage regulations of autophagy by ROS: from induction to maturation","author":"Zhou","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0295","doi-asserted-by":"crossref","first-page":"5501","DOI":"10.3892\/mmr.2015.4091","article-title":"Ascorbic acid inhibits TPA-induced HL-60 cell differentiation by decreasing cellular H2O2 and ERK phosphorylation","volume":"12","author":"Yiang","year":"2015","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.lfs.2022.120481_bb0300","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1080\/19491034.2017.1285989","article-title":"Transcriptomes reflect the phenotypes of undifferentiated, granulocyte and macrophage forms of HL-60\/S4 cells","volume":"8","author":"Mark Welch","year":"2017","journal-title":"Nucleus"},{"key":"10.1016\/j.lfs.2022.120481_bb0305","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1042\/EBC20170035","article-title":"Regulation of selective autophagy: the p62\/SQSTM1 paradigm","volume":"61","author":"Lamark","year":"2017","journal-title":"Essays Biochem."},{"key":"10.1016\/j.lfs.2022.120481_bb0310","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1038\/cdd.2014.102","article-title":"p62\/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells","volume":"21","author":"Trocoli","year":"2014","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.lfs.2022.120481_bb0315","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.molcel.2008.06.001","article-title":"JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy","volume":"30","author":"Wei","year":"2008","journal-title":"Mol. Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0320","doi-asserted-by":"crossref","first-page":"244","DOI":"10.4161\/auto.5.2.7549","article-title":"PKC\u03b4 signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis","volume":"5","author":"Chen","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0325","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aam6641","article-title":"The metabolic regulator mTORC1 controls terminal myeloid differentiation","volume":"2","author":"Lee","year":"2017","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.lfs.2022.120481_bb0330","doi-asserted-by":"crossref","first-page":"12715","DOI":"10.18632\/oncotarget.3011","article-title":"Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion","volume":"5","author":"Leontieva","year":"2014","journal-title":"Oncotarget"},{"key":"10.1016\/j.lfs.2022.120481_bb0335","article-title":"Co-ordinated activation of classical and novel PKC isoforms is required for PMA-induced mTORC1 activation","volume":"12","author":"Liu","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2022.120481_bb0340","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3389\/fmolb.2018.00067","article-title":"LPS induces mTORC1 and mTORC2 activation during monocyte adhesion","volume":"5","author":"Ribeiro","year":"2018","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.lfs.2022.120481_bb0345","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/jnc.12980","article-title":"Coordinated activation of AMP-activated protein kinase, extracellular signal-regulated kinase, and autophagy regulates phorbol myristate acetate-induced differentiation of SH-SY5Y neuroblastoma cells","volume":"133","author":"Zogovic","year":"2015","journal-title":"J. Neurochem."},{"key":"10.1016\/j.lfs.2022.120481_bb0350","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.2337\/db14-1225","article-title":"Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in atherosclerosis","volume":"64","author":"Vasamsetti","year":"2015","journal-title":"Diabetes"},{"key":"10.1016\/j.lfs.2022.120481_bb0355","doi-asserted-by":"crossref","first-page":"23512","DOI":"10.1074\/jbc.271.38.23512","article-title":"Protein kinase C activates the MEK-ERK pathway in a manner independent of ras and dependent on raf","volume":"271","author":"Ueda","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2022.120481_bb0360","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.molcel.2005.06.025","article-title":"RACK1 mediates activation of JNK by protein kinase C","volume":"19","author":"L\u00f3pez-Bergami","year":"2005","journal-title":"Mol. Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0365","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1038\/ncb1634","article-title":"Bif-1 interacts with beclin 1 through UVRAG and regulates autophagy and tumorigenesis","volume":"9","author":"Takahashi","year":"2007","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0370","doi-asserted-by":"crossref","first-page":"713","DOI":"10.4161\/auto.5.5.8524","article-title":"Regulation of beclin 1 in autophagy","volume":"5","author":"Sun","year":"2009","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0375","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1083\/jcb.200712064","article-title":"FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells","volume":"181","author":"Hara","year":"2008","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0380","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1096\/fj.201801198R","article-title":"MPB, a novel berberine derivative, enhances lysosomal and bactericidal properties via TGF-\u03b2-activated kinase 1-dependent activation of the transcription factor EB","volume":"33","author":"Liu","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.lfs.2022.120481_bb0385","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1083\/jcb.200409117","article-title":"JNK antagonizes akt-mediated survival signals by phosphorylating 14-3-3","volume":"170","author":"Sunayama","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.lfs.2022.120481_bb0390","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/hep.26618","article-title":"Regulation of FOXO3 by phosphorylation and methylation in hepatitis C virus infection and alcohol exposure","volume":"59","author":"Tikhanovich","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.lfs.2022.120481_bb0395","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167869","article-title":"Oxidative stress induces mouse follicular granulosa cells apoptosis via JNK\/FoxO1 pathway","volume":"11","author":"Weng","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2022.120481_bb0400","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.molcel.2005.06.009","article-title":"Erk associates with and primes GSK-3\u03b2 for its inactivation resulting in upregulation of \u03b2-catenin","volume":"19","author":"Ding","year":"2005","journal-title":"Mol. Cell"},{"key":"10.1016\/j.lfs.2022.120481_bb0405","doi-asserted-by":"crossref","first-page":"3905","DOI":"10.1111\/j.1432-1033.2004.04327.x","article-title":"Synergistic activation of signalling to extracellular signal-regulated kinases 1 and 2 by epidermal growth factor and 4\u03b2-phorbol 12-myristate 13-acetate","volume":"271","author":"Hornberg","year":"2004","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.lfs.2022.120481_bb0410","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1101\/gad.213827.113","article-title":"A RANKL-PKC\u03b2-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts","volume":"27","author":"Ferron","year":"2013","journal-title":"Genes Dev."},{"key":"10.1016\/j.lfs.2022.120481_bb0415","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1182\/blood-2011-08-372383","article-title":"Induction of autophagy is essential for monocyte-macrophage differentiation","volume":"119","author":"Zhang","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.lfs.2022.120481_bb0420","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1042\/BST20130134","article-title":"Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers","volume":"41","author":"Sarkar","year":"2013","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.lfs.2022.120481_bb0425","doi-asserted-by":"crossref","first-page":"2799","DOI":"10.1038\/ncomms3799","article-title":"Autophagy proteins regulate ERK phosphorylation","volume":"4","author":"Martinez-Lopez","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.lfs.2022.120481_bb0430","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.advenzreg.2007.11.002","article-title":"Src family kinases and the MEK\/ERK pathway in the regulation of myeloid differentiation and myeloid leukemogenesis","volume":"48","author":"Johnson","year":"2008","journal-title":"Adv. Enzym. Regul."},{"key":"10.1016\/j.lfs.2022.120481_bb0435","doi-asserted-by":"crossref","first-page":"4667","DOI":"10.1182\/blood-2002-12-3647","article-title":"Map kinase signaling pathways and hematologic malignancies","volume":"101","author":"Platanias","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.lfs.2022.120481_bb0440","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s12929-019-0557-2","article-title":"Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses","volume":"26","author":"Wu","year":"2019","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.lfs.2022.120481_bb0445","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.leukres.2005.02.019","article-title":"12-O-tetradecanoylphorbol-13-acetate (TPA)-induced dual-specificity phosphatase expression and AML cell survival","volume":"29","author":"Schaar","year":"2005","journal-title":"Leuk. Res."},{"key":"10.1016\/j.lfs.2022.120481_bb0450","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1080\/15548627.2020.1822628","article-title":"The role of autophagy in targeted therapy for acute myeloid leukemia","volume":"17","author":"Du","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.lfs.2022.120481_bb0455","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.2174\/1568026620666200325110444","article-title":"Preclinical and clinical studies on bryostatins, a class of marine-derived protein kinase C modulators: a mini-review","volume":"20","author":"Raghuvanshi","year":"2020","journal-title":"Curr. Top. Med. Chem."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320522001813?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320522001813?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T20:59:06Z","timestamp":1758401946000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320522001813"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":91,"alternative-id":["S0024320522001813"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2022.120481","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MAP kinase-dependent autophagy controls phorbol myristate acetate-induced macrophage differentiation of HL-60 leukemia cells","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2022.120481","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"120481"}}