{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T02:16:31Z","timestamp":1758420991035,"version":"3.44.0"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,11]],"date-time":"2023-06-11T00:00:00Z","timestamp":1686441600000},"content-version":"vor","delay-in-days":283,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005285","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Goi\u00e1s","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005285","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.lfs.2022.120693","type":"journal-article","created":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T12:27:25Z","timestamp":1654604845000},"page":"120693","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats"],"prefix":"10.1016","volume":"304","author":[{"given":"Jo\u00e3o B.R.","family":"Dutra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismaley S.","family":"Lacerda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allancer D.C.","family":"Nunes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda S.M.","family":"Bessa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9rika F.","family":"Jesus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina N.R.","family":"Pontes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lara M.","family":"Naves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo R.","family":"Pedrino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth P.","family":"Mendes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo A.","family":"Fraga-Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana P.","family":"Costa-Fraga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikos","family":"Stergiopulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas M.","family":"Kangussu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 A.G.","family":"Faraco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anderson J.","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos H.","family":"Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.lfs.2022.120693_bb0005","first-page":"1","article-title":"Expanding priorites - confronting chronic disease in countries with low income","volume":"363","author":"Anderson","year":"2010","journal-title":"N.Engl.J."},{"key":"10.1016\/j.lfs.2022.120693_bb0015","series-title":"Prevention, Detection, Evaluation, And Treatment of High Blood Pressure","volume":"04","author":"Aram","year":"2004"},{"issue":"1","key":"10.1016\/j.lfs.2022.120693_bb0020","first-page":"53","article-title":"Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension","volume":"131","author":"Weber","year":"2010","journal-title":"Indian J. Med. Res."},{"issue":"2","key":"10.1016\/j.lfs.2022.120693_bb0025","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1213\/ANE.0000000000000528","article-title":"An update of the role of renin angiotensin in cardiovascular homeostasis","volume":"120","author":"Farag","year":"2015","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.lfs.2022.120693_bb0030","article-title":"New cardiovascular and pulmonary therapeutic strategies based on the angiotensin-converting enzyme 2\/angiotensin-(1\u20137)\/mas receptor axis","volume":"2012","author":"Ferreira","year":"2012","journal-title":"Int. J. Hypertens."},{"issue":"6891","key":"10.1016\/j.lfs.2022.120693_bb0035","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/nature00786","article-title":"Angiotensin-converting enzyme 2 is an essential regulator of heart function","volume":"417","author":"Crackower","year":"2002","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.lfs.2022.120693_bb0040","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.jash.2013.03.002","article-title":"ACE2 deficiency induced perivascular fibrosis and cardiac hypertrophy during postnatal development in mice","volume":"7","author":"Moritani","year":"2013","journal-title":"J.Am.Soc.Hypertens."},{"issue":"8","key":"10.1016\/j.lfs.2022.120693_bb0045","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1172\/JCI16980","article-title":"Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice","volume":"116","author":"Gurley","year":"2006","journal-title":"J. Clin. Investig."},{"issue":"5","key":"10.1016\/j.lfs.2022.120693_bb0050","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1161\/HYPERTENSIONAHA.108.114322","article-title":"Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function","volume":"52","author":"Rentzsch","year":"2008","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.lfs.2022.120693_bb0055","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1152\/physiolgenomics.00312.2005","article-title":"ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR","volume":"27","author":"D\u00edez-Freire","year":"2006","journal-title":"Physiol. Genomics"},{"issue":"11","key":"10.1016\/j.lfs.2022.120693_bb0060","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1164\/rccm.200811-1678OC","article-title":"Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension","volume":"179","author":"Ferreira","year":"2009","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"5","key":"10.1016\/j.lfs.2022.120693_bb0065","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1161\/HYPERTENSIONAHA.107.108944","article-title":"Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents","volume":"51","author":"Hern\u00e1ndez Prada","year":"2008","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.lfs.2022.120693_bb0070","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1113\/expphysiol.2010.055277","article-title":"Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases","volume":"96","author":"Ferreira","year":"2011","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.lfs.2022.120693_bb0075","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.biopha.2018.07.170","article-title":"The ACE 2 activator diminazene aceturate (DIZE) improves left ventricular diastolic dysfunction following myocardial infarction in rats","volume":"107","author":"Castardeli","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"4","key":"10.1016\/j.lfs.2022.120693_bb0080","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1161\/HYPERTENSIONAHA.113.01337","article-title":"Diminazene aceturate enhances angiotensin-converting enzyme 2 activity and attenuates ischemia-induced cardiac pathophysiology","volume":"62","author":"Qi","year":"2013","journal-title":"Hypertension"},{"key":"10.1016\/j.lfs.2022.120693_bb0085","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.lfs.2016.04.036","article-title":"Cardioprotective effects of diminazene aceturate in pressure-overloaded rat hearts","volume":"155","author":"Macedo","year":"2016","journal-title":"Life Sci."},{"key":"10.1016\/j.lfs.2022.120693_bb0090","article-title":"Anti-hypertensive effects of diminazene aceturate: an angiotensin-converting enzyme 2 activator in rats","author":"Maria","year":"2015","journal-title":"Protein Pept. Lett."},{"issue":"6","key":"10.1016\/j.lfs.2022.120693_bb0095","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1164\/rccm.201205-0880OC","article-title":"Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models","volume":"187","author":"Shenoy","year":"2013","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.lfs.2022.120693_bb0100","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0731-7085(02)00450-8","article-title":"Determination of diminazene aceturate in pharmaceutical formulations by HPLC and identification of related substances by LC\/MS","volume":"30","author":"Atsriku","year":"2002","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"15","key":"10.1016\/j.lfs.2022.120693_bb0105","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1016\/S0960-894X(02)00312-8","article-title":"4-Aminoarylguanidine and 4-aminobenzamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors","volume":"12","author":"Spencer","year":"2002","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"10","key":"10.1016\/j.lfs.2022.120693_bb0110","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1211\/0022357044409","article-title":"Degradation of berenil (diminazene aceturate) in acidic aqueous solution","volume":"56","author":"Campbell","year":"2010","journal-title":"J. Pharm. Pharmacol."},{"issue":"81","key":"10.1016\/j.lfs.2022.120693_bb0115","doi-asserted-by":"crossref","first-page":"3014","DOI":"10.1016\/S0021-9258(19)81066-9","article-title":"P-minobenzamidine as a fluorescent probe for the active site of serine proteases","volume":"257","author":"Evans","year":"1982","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.lfs.2022.120693_bb0120","article-title":"The binding of amidines and guanidines as models of the substrate side chain","volume":"240","author":"Mares-guiai","year":"1965","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2022.120693_bb0125","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/apha.12563","article-title":"Visceral adipose tissue-derived serine protease inhibitor augments acetylcholine-induced relaxation via the inhibition of acetylcholine esterase activity in rat isolated mesenteric artery","volume":"216","author":"Kameshima","year":"2016","journal-title":"Acta Physiol."},{"key":"10.1016\/j.lfs.2022.120693_bb0130","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/apha.12139","article-title":"Vaspin prevents methylglyoxal-induced apoptosis in human vascular endothelial cells by inhibiting reactive oxygen species generation","volume":"209","author":"Phalitakul","year":"2013","journal-title":"Acta Physiol."},{"issue":"5","key":"10.1016\/j.lfs.2022.120693_bb0135","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.phrs.2011.06.001","article-title":"Vaspin prevents TNFa -induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF- B and PKC activation in cultured rat vascular smooth muscle cells","volume":"64","author":"Phalitakul","year":"2011","journal-title":"Pharmacol. Res."},{"issue":"1\u20132","key":"10.1016\/j.lfs.2022.120693_bb0140","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"issue":"18","key":"10.1016\/j.lfs.2022.120693_bb0145","doi-asserted-by":"crossref","first-page":"15532","DOI":"10.1074\/jbc.M212934200","article-title":"Novel peptide inhibitors of angiotensin-converting enzyme 2","volume":"278","author":"Huang","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.lfs.2022.120693_bb0150","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.regpep.2004.05.003","article-title":"Cloning and characterization of a secreted form of angiotensin-converting enzyme 2","volume":"122","author":"Huentelman","year":"2004","journal-title":"Regul. Pept."},{"key":"10.1016\/j.lfs.2022.120693_bb0155","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000159093","article-title":"Impaired endothelial relaxations induced by agonists and flow in spontaneously hypertensive rat compared to Wistar-Kyoto rat perfused coronary arteries","volume":"32","author":"Pourageaud","year":"1995","journal-title":"J. Vasc. Res."},{"issue":"6","key":"10.1016\/j.lfs.2022.120693_bb0160","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/01.hjh.0000358834.18311.fc","article-title":"Endothelial dysfunction in spontaneously hypertensive rats: focus on methodological aspects","volume":"27","author":"Bernatova","year":"2009","journal-title":"J. Hypertens."},{"issue":"6","key":"10.1016\/j.lfs.2022.120693_bb0165","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1161\/hy1201.096538","article-title":"Pulse pressure, endothelium function, and arterial stiffness in spontaneously hypertensive rats","volume":"38","author":"Safar","year":"2001","journal-title":"Hypertension (Dallas, Tex: 1979)"},{"key":"10.1016\/j.lfs.2022.120693_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.peptides.2018.10.005","article-title":"BJ-PRO-7A and BJ-PRO-10C induce vasodilatation and inotropic effects in normotensive and hypertensive rats: role of nitric oxide and muscarinic receptors","volume":"110","author":"Nunes","year":"2018","journal-title":"Peptides"},{"issue":"1","key":"10.1016\/j.lfs.2022.120693_bb0175","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1161\/01.RES.0000107195.13573.E4","article-title":"Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells","volume":"94","author":"Kohlstedt","year":"2004","journal-title":"Circ. Res."},{"issue":"5","key":"10.1016\/j.lfs.2022.120693_bb0180","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1161\/HYPERTENSIONAHA.110.167171","article-title":"Angiotensin II binding to angiotensin I-converting enzyme triggers calcium signaling","volume":"57","author":"Guimar\u00e3es","year":"2011","journal-title":"Hypertension"},{"issue":"12","key":"10.1016\/j.lfs.2022.120693_bb0185","article-title":"Chronic inhibition of chemokine receptor CXCR2 attenuates cardiac remodeling and dysfunction in spontaneously hypertensive rats","volume":"1865","author":"Zhang","year":"2019","journal-title":"Biochim. Biophys. ActaMol. Basis Dis."},{"key":"10.1016\/j.lfs.2022.120693_bb0190","series-title":"Is cardiac hypertrophy in spontaneously hypertensive rats the cause or the consequence of oxidative stress?","volume":"31","author":"\u00c1lvarez","year":"2008"},{"issue":"1","key":"10.1016\/j.lfs.2022.120693_bb0195","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1161\/01.RES.75.1.23","article-title":"Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure. Marked upregulation of genes encoding extracellular matrix components","volume":"75","author":"Boluyt","year":"1994","journal-title":"Circ. Res."},{"issue":"6","key":"10.1016\/j.lfs.2022.120693_bb0200","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1161\/01.RES.53.6.767","article-title":"The contractile state as the major determinant in the evolution of left ventricular dysfunction in the spontaneously hypertensive rat","volume":"53","author":"Mirsky","year":"1983","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.lfs.2022.120693_bb0205","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1152\/physrev.00023.2016","article-title":"The ACE2\/angiotensin-(1\u20137)\/MAS axis of the renin-angiotensin system: focus on angiotensin-(1\u20137)","volume":"98","author":"Santos","year":"2018","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.lfs.2022.120693_bb0210","article-title":"Microbial serine protease inhibitors and their therapeutic applications","volume":"17","author":"Harish","year":"2017","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.lfs.2022.120693_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.aller.2016.10.011","article-title":"A critical review on serine protease: key immune","author":"Patel","year":"2017","journal-title":"Allergol. Immunopathol."},{"key":"10.1016\/j.lfs.2022.120693_bb0220","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/cei.12574","article-title":"Plasma levels of mannan-binding lectin-associated serine proteases MASP-1 and MASP-2 are elevated in type 1 diabetes and correlate with glycaemic control","volume":"180","author":"Jenny","year":"2014","journal-title":"Clin.Exp.Immunol."},{"key":"10.1016\/j.lfs.2022.120693_bb0225","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.bbapap.2004.09.005","article-title":"Serine proteases and cardiac function","volume":"1751","author":"Wu","year":"2005","journal-title":"Biochim.Biophys.Acta"},{"key":"10.1016\/j.lfs.2022.120693_bb0230","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1080\/15216540215672","article-title":"Clonidine displacement from type 1 imidazoline receptor by p-aminobenzamidine, the prototype of trypsin-like serine protease inhibitors","volume":"54","author":"Pallottini","year":"2002","journal-title":"IUBMB Life"},{"issue":"2","key":"10.1016\/j.lfs.2022.120693_bb0235","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.jphs.2016.09.005","article-title":"A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity","volume":"132","author":"Kakizoe","year":"2016","journal-title":"J.Pharmacol.Sci."},{"key":"10.1016\/j.lfs.2022.120693_bb0240","first-page":"1","article-title":"Visceral adipose tissue-derived serine protease inhibitor prevents the development of monocrotaline-induced pulmonary arterial hypertension in rats","author":"Sakamoto","year":"2017","journal-title":"Eur. J. Physiol."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320522003939?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320522003939?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T20:59:19Z","timestamp":1758401959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320522003939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":47,"alternative-id":["S0024320522003939"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2022.120693","relation":{},"ISSN":["0024-3205"],"issn-type":[{"type":"print","value":"0024-3205"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2022.120693","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120693"}}