{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:46:15Z","timestamp":1792442775726,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004748","name":"Mashhad University of Medical Sciences","doi-asserted-by":"publisher","award":["4000774"],"award-info":[{"award-number":["4000774"]}],"id":[{"id":"10.13039\/501100004748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.lfs.2023.121495","type":"journal-article","created":{"date-parts":[[2023,2,11]],"date-time":"2023-02-11T23:39:22Z","timestamp":1676158762000},"page":"121495","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"special_numbering":"C","title":["Gold-containing liposomes and glucose-coated gold nanoparticles enhances the radiosensitivity of B16F0 melanoma cells via increasing apoptosis and ROS production"],"prefix":"10.1016","volume":"318","author":[{"given":"Abolfazl","family":"Bemidinezhad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farshad","family":"Mirzavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Gholamhosseinian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Gheybi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Soukhtanloo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.lfs.2023.121495_bb0005","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1200\/OP.21.00686","article-title":"Managing metastatic melanoma in 2022: a clinical review","volume":"18","author":"Switzer","year":"2022","journal-title":"JCO Oncol. Pract."},{"key":"10.1016\/j.lfs.2023.121495_bb0010","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.biochi.2020.06.001","article-title":"The therapeutic potential of targeting CD73 and CD73-derived adenosine in melanoma","volume":"176","author":"Soleimani","year":"2020","journal-title":"Biochimie"},{"issue":"1\u20133","key":"10.1016\/j.lfs.2023.121495_bb0015","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.mrrev.2010.01.002","article-title":"Enhancement of radiation effect by heavy elements","volume":"704","author":"Kobayashi","year":"2010","journal-title":"Mutat. Res. Rev. Mutat. Res."},{"issue":"3","key":"10.1016\/j.lfs.2023.121495_bb0020","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.radonc.2013.06.013","article-title":"Ionizing-radiation induced DNA double-strand breaks: a direct and indirect lighting up","volume":"108","author":"Vignard","year":"2013","journal-title":"Radiother. Oncol."},{"issue":"7","key":"10.1016\/j.lfs.2023.121495_bb0025","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/S1470-2045(05)70246-1","article-title":"New insights on cell death from radiation exposure","volume":"6","author":"Prise","year":"2005","journal-title":"Lancet Oncol."},{"issue":"4","key":"10.1016\/j.lfs.2023.121495_bb0030","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s13277-010-0042-8","article-title":"Radiation-induced cell death mechanisms","volume":"31","author":"Eriksson","year":"2010","journal-title":"Tumor Biol."},{"issue":"6","key":"10.1016\/j.lfs.2023.121495_bb0035","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1667\/RR1984.1","article-title":"Gold nanoparticles as radiation sensitizers in cancer therapy","volume":"173","author":"Chithrani","year":"2010","journal-title":"Radiat. Res."},{"issue":"2","key":"10.1016\/j.lfs.2023.121495_bb0040","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s11095-010-0318-0","article-title":"Inorganic nanoparticles in cancer therapy","volume":"28","author":"Bhattacharyya","year":"2011","journal-title":"Pharm. Res."},{"issue":"4","key":"10.1016\/j.lfs.2023.121495_bb0045","doi-asserted-by":"crossref","first-page":"293","DOI":"10.2217\/fvl-2015-0010","article-title":"Gold nanoparticles and their applications in biomedicine","volume":"11","author":"Versiani","year":"2016","journal-title":"Futur. Virol."},{"key":"10.1016\/j.lfs.2023.121495_bb0050","doi-asserted-by":"crossref","first-page":"9407","DOI":"10.2147\/IJN.S272902","article-title":"Gold nanoparticles as radiosensitizers in cancer radiotherapy","volume":"15","author":"Chen","year":"2020","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.lfs.2023.121495_bb0055","article-title":"Toxicity of gold nanoparticles (AuNPs): a review","volume":"26","author":"Sani","year":"2021","journal-title":"Biochem. Biophys. Rep."},{"issue":"10","key":"10.1016\/j.lfs.2023.121495_bb0060","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1016\/j.bbamem.2009.06.022","article-title":"Nanoparticles evading the reticuloendothelial system: role of the supported bilayer","volume":"1788","author":"Li","year":"2009","journal-title":"Biochim. Biophys. Acta Biomembr."},{"key":"10.1016\/j.lfs.2023.121495_bb0065","doi-asserted-by":"crossref","first-page":"975","DOI":"10.2147\/IJN.S68861","article-title":"Liposomes as nanomedical devices","volume":"10","author":"Bozzuto","year":"2015","journal-title":"Int. J. Nanomedicine"},{"issue":"1","key":"10.1016\/j.lfs.2023.121495_bb0070","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19010195","article-title":"Surface functionalization and targeting strategies of liposomes in solid tumor therapy: a review","volume":"19","author":"Riaz","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2023.121495_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2021.121396","article-title":"Pegylated liposomal encapsulation improves the antitumor efficacy of combretastatin A4 in murine 4T1 triple-negative breast cancer model","volume":"613","author":"Mirzavi","year":"2022","journal-title":"Int. J. Pharm."},{"issue":"8","key":"10.1016\/j.lfs.2023.121495_bb0080","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1002\/chem.200500925","article-title":"Facile \u201cgreen\u201d synthesis, characterization, and catalytic function of \u03b2-D-glucose-stabilized Au nanocrystals","volume":"12","author":"Liu","year":"2006","journal-title":"Chem. Eur. J."},{"issue":"4","key":"10.1016\/j.lfs.2023.121495_bb0085","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1080\/09553002.2017.1268282","article-title":"Increased radiotoxicity in two cancerous cell lines irradiated by low and high energy photons in the presence of thio-glucose bound gold nanoparticles","volume":"93","author":"Soleymanifard","year":"2017","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.lfs.2023.121495_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.jphotobiol.2020.111812","article-title":"Enhancement of the biological autoluminescence by Mito-liposomal gold nanoparticle nanocarriers","volume":"204","author":"Sardarabadi","year":"2020","journal-title":"J. Photochem. Photobiol. B Biol."},{"issue":"1","key":"10.1016\/j.lfs.2023.121495_bb0095","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s13014-021-01751-3","article-title":"Radiosensitization of breast cancer cells using AS1411 aptamer-conjugated gold nanoparticles","volume":"16","author":"Mehrnia","year":"2021","journal-title":"Radiat. Oncol."},{"issue":"5","key":"10.1016\/j.lfs.2023.121495_bb0100","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1177\/10915818221104417","article-title":"Tumor-inhibitory effects of zerumbone against HT-29 human colorectal cancer cells","volume":"41","author":"Memari","year":"2022","journal-title":"Int. J. Toxicol."},{"issue":"4","key":"10.1016\/j.lfs.2023.121495_bb0105","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"issue":"4","key":"10.1016\/j.lfs.2023.121495_bb0110","first-page":"1461","article-title":"Preparation of 2-deoxy-D-glucose coated spio nanoparticles and characterization of their physical, chemical, and biological properties","volume":"9","author":"Maharramov","year":"2014","journal-title":"Dig. J. Nanomater. Biostruct."},{"issue":"6","key":"10.1016\/j.lfs.2023.121495_bb0115","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0178202","article-title":"Synthesis of a novel glucose capped gold nanoparticle as a better theranostic candidate","volume":"12","author":"Suvarna","year":"2017","journal-title":"PloS one"},{"key":"10.1016\/j.lfs.2023.121495_bb0120","doi-asserted-by":"crossref","first-page":"15","DOI":"10.26850\/1678-4618eqj.v31.3.2006.p15-21","article-title":"Analysis of the structure and vibrational spectra of glucose and fructose","volume":"31","author":"Ibrahim","year":"2006","journal-title":"Ecletica Quim."},{"issue":"4","key":"10.1016\/j.lfs.2023.121495_bb0125","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1002\/smll.200901622","article-title":"The effects of size, shape, and surface functional group of gold nanostructures on their adsorption and internalization by cells","volume":"6","author":"Cho","year":"2010","journal-title":"Small"},{"issue":"4","key":"10.1016\/j.lfs.2023.121495_bb0130","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1021\/nl052396o","article-title":"Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells","volume":"6","author":"Chithrani","year":"2006","journal-title":"Nano Lett."},{"issue":"1","key":"10.1016\/j.lfs.2023.121495_bb0135","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1269\/jrr.10068","article-title":"Size, concentration and incubation time dependence of gold nanoparticle uptake into pancreas cancer cells and its future application to X-ray drug delivery system","volume":"52","author":"Trono","year":"2011","journal-title":"J. Radiat. Res."},{"issue":"15","key":"10.1016\/j.lfs.2023.121495_bb0140","doi-asserted-by":"crossref","first-page":"13037","DOI":"10.1021\/acsami.7b01112","article-title":"Shape-dependent radiosensitization effect of gold nanostructures in cancer radiotherapy: comparison of gold nanoparticles, nanospikes, and nanorods","volume":"9","author":"Ma","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"4","key":"10.1016\/j.lfs.2023.121495_bb0145","first-page":"328","article-title":"Green synthesis of glucose-coated gold nanoparticles for improving radiosensitivity in human U87 glioblastoma cell line","volume":"9","author":"Bemidinezhad","year":"2022","journal-title":"Nanomed. J."},{"key":"10.1016\/j.lfs.2023.121495_bb0150","first-page":"2020","article-title":"Curcumin and glu-GNPs induce radiosensitivity against breast cancer stem-like cells","author":"Yang","year":"2020","journal-title":"Biomed. Res. Int."},{"issue":"2","key":"10.1016\/j.lfs.2023.121495_bb0155","doi-asserted-by":"crossref","first-page":"597","DOI":"10.3892\/ijo.2012.1721","article-title":"Smart gold nanoparticles enhance killing effect on cancer cells","volume":"42","author":"Song","year":"2013","journal-title":"Int. J. Oncol."},{"issue":"6","key":"10.1016\/j.lfs.2023.121495_bb0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0269603","article-title":"Glucose-coated superparamagnetic iron oxide nanoparticles prepared by metal vapor synthesis can target GLUT1 overexpressing tumors: in vitro tests and in vivo preliminary assessment","volume":"17","author":"Barbaro","year":"2022","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.lfs.2023.121495_bb0165","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1124\/dmd.112.044925","article-title":"Nano-advantage in enhanced drug delivery with biodegradable nanoparticles: contribution of reduced clearance","volume":"40","author":"Kadam","year":"2012","journal-title":"Drug Metab. Dispos."},{"issue":"6","key":"10.1016\/j.lfs.2023.121495_bb0170","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.ceb.2003.10.009","article-title":"Mechanisms of caspase activation","volume":"15","author":"Boatright","year":"2003","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.lfs.2023.121495_bb0175","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1471-2121-14-32","article-title":"Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis","volume":"14","author":"Brentnall","year":"2013","journal-title":"BMC Cell Biol."},{"issue":"6","key":"10.1016\/j.lfs.2023.121495_bb0180","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.cell.2017.08.028","article-title":"Putting p53 in context","volume":"170","author":"Kastenhuber","year":"2017","journal-title":"Cell"},{"issue":"19","key":"10.1016\/j.lfs.2023.121495_bb0185","doi-asserted-by":"crossref","DOI":"10.3390\/nano12193324","article-title":"Green synthesis of gold nanoparticles and study of their inhibitory effect on bulk cancer cells and cancer stem cells in breast carcinoma","volume":"12","author":"Wang","year":"2022","journal-title":"Nanomaterials (Basel)"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320523001297?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320523001297?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:34:10Z","timestamp":1736382850000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320523001297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":37,"alternative-id":["S0024320523001297"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2023.121495","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gold-containing liposomes and glucose-coated gold nanoparticles enhances the radiosensitivity of B16F0 melanoma cells via increasing apoptosis and ROS production","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2023.121495","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"121495"}}