{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T14:56:19Z","timestamp":1780671379276,"version":"3.54.1"},"reference-count":111,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.lfs.2023.121804","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T15:08:16Z","timestamp":1685113696000},"page":"121804","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["The role of fibroblast growth factor 7 in cartilage development and diseases"],"prefix":"10.1016","volume":"326","author":[{"given":"Xinyue","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohua","family":"Pu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caixia","family":"Pi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8156-0322","authenticated-orcid":false,"given":"Jing","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2023.121804_bb0005","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/nrm3528","article-title":"Exploring mechanisms of FGF signalling through the lens of structural biology","volume":"14","author":"Goetz","year":"2013","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.lfs.2023.121804_bb0010","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1089\/neu.2009.1108","article-title":"FGF-2-responsive and spinal cord-resident cells improve locomotor function after spinal cord injury","volume":"31","author":"Kasai","year":"2014","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.lfs.2023.121804_bb0015","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/bs.ctdb.2022.03.005","article-title":"Cell signaling pathways controlling an axis organizing center in the zebrafish","volume":"150","author":"Jones","year":"2022","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.lfs.2023.121804_bb0020","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0142-9612(99)00207-0","article-title":"Accelerated tissue regeneration through incorporation of basic fibroblast growth factor-impregnated gelatin microspheres into artificial dermis","volume":"21","author":"Kawai","year":"2000","journal-title":"Biomaterials"},{"key":"10.1016\/j.lfs.2023.121804_bb0025","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.15252\/embj.201490578","article-title":"FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord","volume":"34","author":"Jacobi","year":"2015","journal-title":"EMBO J."},{"key":"10.1016\/j.lfs.2023.121804_bb0030","doi-asserted-by":"crossref","first-page":"638","DOI":"10.2353\/ajpath.2008.070897","article-title":"Excess FGF-7 in corneal epithelium causes corneal intraepithelial neoplasia in young mice and epithelium hyperplasia in adult mice","volume":"172","author":"Chikama","year":"2008","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.lfs.2023.121804_bb0035","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/dvdy.24097","article-title":"FGF7 signals are relayed to autocrine EGF family growth factors to induce branching morphogenesis of mouse salivary epithelium","volume":"243","author":"Kera","year":"2014","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.lfs.2023.121804_bb0040","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/s41586-022-04752-8","article-title":"Developmental dynamics of two bipotent thymic epithelial progenitor types","volume":"606","author":"Nusser","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.lfs.2023.121804_bb0045","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1126\/science.2475908","article-title":"Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth","volume":"245","author":"Finch","year":"1989","journal-title":"Science"},{"key":"10.1016\/j.lfs.2023.121804_bb0050","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.cmet.2015.02.005","article-title":"GLP-1R agonists promote normal and neoplastic intestinal growth through mechanisms requiring Fgf7","volume":"21","author":"Koehler","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.lfs.2023.121804_bb0055","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1172\/JCI2792","article-title":"Interactions between stromal cell-derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia","volume":"102","author":"Bajaj-Elliott","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.lfs.2023.121804_bb0060","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1073\/pnas.89.1.246","article-title":"Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene","volume":"89","author":"Miki","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.lfs.2023.121804_bb0065","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1196\/annals.1402.059","article-title":"The role of the perichondrium in fetal bone development","volume":"1116","author":"Kronenberg","year":"2007","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0070","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.joca.2020.10.010","article-title":"The role of stromal cell-derived factor 1 on cartilage development and disease","volume":"29","author":"Li","year":"2021","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.lfs.2023.121804_bb0075","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/s41413-022-00239-4","article-title":"The role of TGF-beta3 in cartilage development and osteoarthritis","volume":"11","author":"Du","year":"2023","journal-title":"Bone Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0080","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1126\/science.1222454","article-title":"Unlike bone, cartilage regeneration remains elusive","volume":"338","author":"Huey","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.lfs.2023.121804_bb0085","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1177\/0363546518756087","article-title":"Anterior cruciate ligament transection-induced cellular and extracellular events in menisci: implications for osteoarthritis","volume":"46","author":"Xie","year":"2018","journal-title":"Am. J. Sports Med."},{"key":"10.1016\/j.lfs.2023.121804_bb0090","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1210\/js.2018-00105","article-title":"Fibroblast growth factor 2 and its receptors in bone biology and disease","volume":"2","author":"Coffin","year":"2018","journal-title":"J. Endocr. Soc."},{"key":"10.1016\/j.lfs.2023.121804_bb0095","doi-asserted-by":"crossref","first-page":"11191","DOI":"10.4238\/2015.September.22.13","article-title":"Upregulation of fibroblast growth factor 1 in the synovial membranes of patients with late stage osteoarthritis","volume":"14","author":"Li","year":"2015","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0100","doi-asserted-by":"crossref","first-page":"R90","DOI":"10.1186\/ar2474","article-title":"Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis","volume":"10","author":"Uchii","year":"2008","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.lfs.2023.121804_bb0105","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12964-023-01069-5","article-title":"FGF19 increases mitochondrial biogenesis and fusion in chondrocytes via the AMPK\u03b1-p38\/MAPK pathway","volume":"21","author":"Kan","year":"2023","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.lfs.2023.121804_bb0110","doi-asserted-by":"crossref","first-page":"10192","DOI":"10.1074\/jbc.M113.524090","article-title":"Identification of fibroblast growth factor-18 as a molecule to protect adult articular cartilage by gene expression profiling","volume":"289","author":"Mori","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2023.121804_bb0115","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1016\/j.joca.2016.07.005","article-title":"Exogenous fibroblast growth factor 9 attenuates cartilage degradation and aggravates osteophyte formation in post-traumatic osteoarthritis","volume":"24","author":"Zhou","year":"2016","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.lfs.2023.121804_bb0120","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/aja.1002030210","article-title":"Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal-epithelial interactions","volume":"203","author":"Finch","year":"1995","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.lfs.2023.121804_bb0125","doi-asserted-by":"crossref","first-page":"3862","DOI":"10.7150\/ijbs.65240","article-title":"FGF7-induced E11 facilitates cell-cell communication through connexin43","volume":"17","author":"Liu","year":"2021","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0130","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1101\/gad.266551.115","article-title":"Fibroblast growth factor signaling in skeletal development and disease","volume":"29","author":"Ornitz","year":"2015","journal-title":"Genes Dev."},{"key":"10.1016\/j.lfs.2023.121804_bb0135","doi-asserted-by":"crossref","first-page":"14792","DOI":"10.1038\/s41598-018-33247-8","article-title":"FGF-7 dictates osteocyte cell processes through beta-catenin transduction","volume":"8","author":"Liu","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2023.121804_bb0140","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s00774-016-0784-5","article-title":"Local delivery of recombinant human FGF7 enhances bone formation in rat mandible defects","volume":"35","author":"Poudel","year":"2017","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.lfs.2023.121804_bb0145","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/s41584-020-0469-2","article-title":"Fibroblast growth factor signalling in osteoarthritis and cartilage repair","volume":"16","author":"Xie","year":"2020","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.lfs.2023.121804_bb0150","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.actbio.2018.12.031","article-title":"Multi-layered PLLA-nanosheets loaded with FGF-2 induce robust bone regeneration with controlled release in critical-sized mouse femoral defects","volume":"85","author":"Murahashi","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.lfs.2023.121804_bb0155","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.actbio.2018.01.039","article-title":"Targeted delivery of FGF2 to subchondral bone enhanced the repair of articular cartilage defect","volume":"69","author":"Yang","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.lfs.2023.121804_bb0160","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/wdev.176","article-title":"The fibroblast growth factor signaling pathway","volume":"4","author":"Ornitz","year":"2015","journal-title":"Wiley Interdiscip. Rev. Dev. Biol."},{"key":"10.1016\/j.lfs.2023.121804_bb0165","doi-asserted-by":"crossref","first-page":"162","DOI":"10.2106\/00004623-198769020-00002","article-title":"Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth","volume":"69","author":"Hunziker","year":"1987","journal-title":"J. Bone Joint Surg. Am."},{"key":"10.1016\/j.lfs.2023.121804_bb0170","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.devcel.2011.12.024","article-title":"Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes","volume":"22","author":"Dy","year":"2012","journal-title":"Dev. Cell"},{"key":"10.1016\/j.lfs.2023.121804_bb0175","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1083\/jcb.102.4.1151","article-title":"Collagen gene expression during limb cartilage differentiation","volume":"102","author":"Kosher","year":"1986","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.lfs.2023.121804_bb0180","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1242\/dev.114.1.233","article-title":"Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse","volume":"114","author":"Peters","year":"1992","journal-title":"Development"},{"key":"10.1016\/j.lfs.2023.121804_bb0185","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1002\/aja.1002040410","article-title":"Changes in the expression of fibroblast growth factor receptors mark distinct stages of chondrogenesis in vitro and during chick limb skeletal patterning","volume":"204","author":"Szebenyi","year":"1995","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.lfs.2023.121804_bb0190","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0092-8674(00)81069-7","article-title":"Fibroblast growth factor receptor 3 is a negative regulator of bone growth","volume":"84","author":"Deng","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.lfs.2023.121804_bb0195","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.1093\/hmg\/ddv019","article-title":"FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation","volume":"24","author":"Karolak","year":"2015","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.lfs.2023.121804_bb0200","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1073\/pnas.97.3.1113","article-title":"Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway","volume":"97","author":"Murakami","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.lfs.2023.121804_bb0205","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1242\/dev.023176","article-title":"Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development","volume":"135","author":"ten Berge","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.lfs.2023.121804_bb0210","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.celrep.2014.07.038","article-title":"Fibroblast growth factor maintains chondrogenic potential of limb bud mesenchymal cells by modulating DNMT3A recruitment","volume":"8","author":"Kumar","year":"2014","journal-title":"Cell Rep."},{"key":"10.1016\/j.lfs.2023.121804_bb0215","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1101\/gad.965602","article-title":"Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18","volume":"16","author":"Liu","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.lfs.2023.121804_bb0220","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1101\/gad.965702","article-title":"FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis","volume":"16","author":"Ohbayashi","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.lfs.2023.121804_bb0225","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s11010-013-1716-5","article-title":"Fibroblast growth factor-7 facilitates osteogenic differentiation of embryonic stem cells through the activation of ERK\/Runx2 signaling","volume":"382","author":"Jeon","year":"2013","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.lfs.2023.121804_bb0230","doi-asserted-by":"crossref","first-page":"6972","DOI":"10.1074\/jbc.274.11.6972","article-title":"Cbfa1 isoforms exert functional differences in osteoblast differentiation","volume":"274","author":"Harada","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2023.121804_bb0235","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0092-8674(00)80257-3","article-title":"Osf2\/Cbfa1: a transcriptional activator of osteoblast differentiation","volume":"89","author":"Ducy","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.lfs.2023.121804_bb0240","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1093\/abbs\/gmab136","article-title":"PDGF-AA promotes cell-to-cell communication in osteocytes through PI3K\/Akt signaling pathway","volume":"53","author":"Liu","year":"2021","journal-title":"Acta Biochim. Biophys. Sin. Shanghai"},{"key":"10.1016\/j.lfs.2023.121804_bb0245","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41368-021-00119-3","article-title":"Transforming growth factor-\u03b21-induced N-cadherin drives cell-cell communication through connexin43 in osteoblast lineage","volume":"13","author":"Yang","year":"2021","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0250","doi-asserted-by":"crossref","first-page":"4187","DOI":"10.1242\/jcs.03162","article-title":"Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43","volume":"119","author":"Chung","year":"2006","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0255","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/s41368-020-0086-6","article-title":"Gap junction-mediated cell-to-cell communication in oral development and oral diseases: a concise review of research progress","volume":"12","author":"Liu","year":"2020","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0260","doi-asserted-by":"crossref","first-page":"E478","DOI":"10.1073\/pnas.1409857112","article-title":"Osteocytes mediate the anabolic actions of canonical Wnt\/\u03b2-catenin signaling in bone","volume":"112","author":"Tu","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.lfs.2023.121804_bb0265","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nm.3074","article-title":"WNT signaling in bone homeostasis and disease: from human mutations to treatments","volume":"19","author":"Baron","year":"2013","journal-title":"Nat. Med."},{"key":"10.1016\/j.lfs.2023.121804_bb0270","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/382638a0","article-title":"Functional interaction of beta-catenin with the transcription factor LEF-1","volume":"382","author":"Behrens","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.lfs.2023.121804_bb0275","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.actbio.2018.08.018","article-title":"Substrate elasticity regulates adipose-derived stromal cell differentiation towards osteogenesis and adipogenesis through \u03b2-catenin transduction","volume":"79","author":"Xie","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.lfs.2023.121804_bb0280","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S0014-5793(03)00909-8","article-title":"Structure-based mutational analyses in FGF7 identify new residues involved in specific interaction with FGFR2IIIb","volume":"552","author":"Sher","year":"2003","journal-title":"FEBS Lett."},{"key":"10.1016\/j.lfs.2023.121804_bb0285","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1186\/s12891-021-04516-x","article-title":"The protective mechanism of SIRT1 on cartilage through regulation of LEF-1","volume":"22","author":"Hu","year":"2021","journal-title":"BMC Musculoskelet. Disord."},{"key":"10.1016\/j.lfs.2023.121804_bb0290","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.1128\/MCB.02120-05","article-title":"E11\/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation","volume":"26","author":"Zhang","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.lfs.2023.121804_bb0295","doi-asserted-by":"crossref","first-page":"598","DOI":"10.7150\/ijbs.29582","article-title":"A novel role of Cx43-composed GJIC in PDT phototoxicity: an implication of Cx43 for the enhancement of PDT efficacy","volume":"15","author":"Wu","year":"2019","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2023.110605","article-title":"IL-10 enhances cell-to-cell communication in chondrocytes via STAT3 signaling pathway","volume":"105","author":"Guo","year":"2023","journal-title":"Cell. Signal."},{"key":"10.1016\/j.lfs.2023.121804_bb0305","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0925-4773(98)00210-X","article-title":"Regulation of chondrocyte differentiation by Cbfa1","volume":"80","author":"Kim","year":"1999","journal-title":"Mech. Dev."},{"key":"10.1016\/j.lfs.2023.121804_bb0310","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20071694","article-title":"Regulation of proliferation, differentiation and functions of osteoblasts by Runx2","volume":"20","author":"Komori","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0315","doi-asserted-by":"crossref","first-page":"2937","DOI":"10.1101\/gad.1482906","article-title":"Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium","volume":"20","author":"Hinoi","year":"2006","journal-title":"Genes Dev."},{"key":"10.1016\/j.lfs.2023.121804_bb0320","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1359\/jbmr.071025","article-title":"Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2","volume":"23","author":"Usui","year":"2008","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0325","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1002\/jor.22448","article-title":"Connexin 43 is a potential regulator in fluid shear stress-induced signal transduction in osteocytes","volume":"31","author":"Li","year":"2013","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0330","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/nrrheum.2017.204","article-title":"Joint diseases: from connexins to gap junctions","volume":"14","author":"Donahue","year":"2017","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.lfs.2023.121804_bb0335","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1080\/03008207.2019.1593394","article-title":"The involvement of the ERK-MAPK pathway in TGF-\u03b21-mediated connexin43-gap junction formation in chondrocytes","volume":"60","author":"Wang","year":"2019","journal-title":"Connect. Tissue Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0340","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1089\/ten.tea.2014.0673","article-title":"Direct cell-cell contact with chondrocytes is a key mechanism in multipotent mesenchymal stromal cell-mediated chondrogenesis","volume":"21","author":"de Windt","year":"2015","journal-title":"Tissue Eng. Part A"},{"key":"10.1016\/j.lfs.2023.121804_bb0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2021.119175","article-title":"TGF-\u03b22 increases cell-cell communication in chondrocytes via p-Smad3 signalling","volume":"1869","author":"Duan","year":"2022","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0350","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/s41420-019-0221-3","article-title":"TGF-\u03b21 facilitates cell-cell communication in osteocytes via connexin43- and pannexin1-dependent gap junctions","volume":"5","author":"Liu","year":"2019","journal-title":"Cell Death. Discov."},{"key":"10.1016\/j.lfs.2023.121804_bb0355","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/abbs\/gmab021","article-title":"Lipid metabolism in cartilage and its diseases: a concise review of the research progress","volume":"53","author":"Yang","year":"2021","journal-title":"Acta Biochim. Biophys. Sin. Shanghai"},{"key":"10.1016\/j.lfs.2023.121804_bb0360","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S0140-6736(14)60802-3","article-title":"Osteoarthritis","volume":"386","author":"Glyn-Jones","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.lfs.2023.121804_bb0365","doi-asserted-by":"crossref","first-page":"1102S","DOI":"10.1177\/19476035211063858","article-title":"Role of mitochondria in physiology of chondrocytes and diseases of osteoarthritis and rheumatoid arthritis","volume":"13","author":"Kan","year":"2021","journal-title":"Cartilage."},{"key":"10.1016\/j.lfs.2023.121804_bb0370","doi-asserted-by":"crossref","first-page":"16072","DOI":"10.1038\/nrdp.2016.72","article-title":"Osteoarthritis","volume":"2","author":"Martel-Pelletier","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.lfs.2023.121804_bb0375","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.joca.2007.12.013","article-title":"OARSI recommendations for the management of hip and knee osteoarthritis, part II: OARSI evidence-based, expert consensus guidelines","volume":"16","author":"Zhang","year":"2008","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.lfs.2023.121804_bb0380","doi-asserted-by":"crossref","first-page":"14003","DOI":"10.1038\/boneres.2014.3","article-title":"Role of FGF\/FGFR signaling in skeletal development and homeostasis: learning from mouse models","volume":"2","author":"Su","year":"2014","journal-title":"Bone Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0385","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1302\/2046-3758.108.BJR-2021-0086","article-title":"The role of TGF-\u03b22 in cartilage development and diseases","volume":"10","author":"Duan","year":"2021","journal-title":"Bone Joint Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0390","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.joca.2005.02.003","article-title":"Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis","volume":"13","author":"Daouti","year":"2005","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.lfs.2023.121804_bb0395","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1111\/jcmm.17174","article-title":"The role of fibroblast growth factor 8 in cartilage development and disease","volume":"26","author":"Chen","year":"2022","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.lfs.2023.121804_bb0400","doi-asserted-by":"crossref","first-page":"3982","DOI":"10.1002\/art.34645","article-title":"Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice","volume":"64","author":"Weng","year":"2012","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.lfs.2023.121804_bb0405","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2020.153305","article-title":"Safflower yellow alleviates osteoarthritis and prevents inflammation by inhibiting PGE2 release and regulating NF-\u03baB\/SIRT1\/AMPK signaling pathways","volume":"78","author":"Wang","year":"2020","journal-title":"Phytomedicine."},{"key":"10.1016\/j.lfs.2023.121804_bb0410","first-page":"2432","article-title":"Fibroblast growth factor receptor 3 inhibits osteoarthritis progression in the knee joints of adult mice, arthritis","volume":"68","author":"Tang","year":"2016","journal-title":"Rheumatol."},{"key":"10.1016\/j.lfs.2023.121804_bb0415","doi-asserted-by":"crossref","first-page":"R2","DOI":"10.1093\/hmg\/ddv419","article-title":"Advances in treatment of achondroplasia and osteoarthritis","volume":"25","author":"Klag","year":"2016","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.lfs.2023.121804_bb0420","doi-asserted-by":"crossref","first-page":"3498","DOI":"10.1002\/art.24025","article-title":"Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage","volume":"58","author":"Sawaji","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.lfs.2023.121804_bb0425","first-page":"2447","article-title":"Effects of fibroblast growth factors 2 and low intensity pulsed ultrasound on the repair of knee articular cartilage in rabbits","volume":"22","author":"Tang","year":"2018","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.153945","article-title":"Atractylenolide-1 targets SPHK1 and B4GALT2 to regulate intestinal metabolism and flora composition to improve inflammation in mice with colitis","volume":"98","author":"Qu","year":"2022","journal-title":"Phytomedicine."},{"key":"10.1016\/j.lfs.2023.121804_bb0435","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1002\/jcp.21317","article-title":"Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes","volume":"215","author":"Im","year":"2008","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.lfs.2023.121804_bb0440","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s12079-017-0384-8","article-title":"Catabolic effects of FGF-1 on chondrocytes and its possible role in osteoarthritis","volume":"11","author":"El-Seoudi","year":"2017","journal-title":"J. Cell Commun. Signal."},{"key":"10.1016\/j.lfs.2023.121804_bb0445","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.joca.2020.09.006","article-title":"Transcriptional response of human articular chondrocytes treated with fibronectin fragments: an in vitro model of the osteoarthritis phenotype","volume":"29","author":"Reed","year":"2021","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.lfs.2023.121804_bb0450","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.1002\/art.38762","article-title":"Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage","volume":"66","author":"Jeffries","year":"2014","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.lfs.2023.121804_bb0455","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/s41413-021-00173-x","article-title":"Runx1 protects against the pathological progression of osteoarthritis","volume":"9","author":"Zhou","year":"2021","journal-title":"Bone Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0460","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1002\/jbmr.3737","article-title":"Chondrocyte-specific RUNX2 overexpression accelerates post-traumatic osteoarthritis progression in adult mice","volume":"34","author":"Catheline","year":"2019","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0465","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1359\/jbmr.080617","article-title":"Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo","volume":"23","author":"Plotkin","year":"2008","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0470","doi-asserted-by":"crossref","first-page":"12165","DOI":"10.1074\/jbc.271.21.12165","article-title":"Gap junctional intercellular communication contributes to hormonal responsiveness in osteoblastic networks","volume":"271","author":"Vander Molen","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2023.121804_bb0475","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1091\/mbc.e04-01-0043","article-title":"Ribosomal S6 kinase as a mediator of keratinocyte growth factor-induced activation of Akt in epithelial cells","volume":"15","author":"Pan","year":"2004","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.lfs.2023.121804_bb0480","doi-asserted-by":"crossref","first-page":"6098","DOI":"10.1073\/pnas.1031851100","article-title":"Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia","volume":"100","author":"Ray","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.lfs.2023.121804_bb0485","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1167\/iovs.04-1487","article-title":"KGF prevents oxygen-mediated damage in ARPE-19 cells","volume":"46","author":"Geiger","year":"2005","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0490","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1098\/rstb.2004.1464","article-title":"Fibroblast growth factors in epithelial repair and cytoprotection","volume":"359","author":"Braun","year":"2004","journal-title":"Philos. Trans. R. Soc. Lond. B. Biol. Sci."},{"key":"10.1016\/j.lfs.2023.121804_bb0495","doi-asserted-by":"crossref","first-page":"625","DOI":"10.3724\/abbs.2022042","article-title":"Osteoblasts induce glucose-derived ATP perturbations in chondrocytes through noncontact communication","volume":"54","author":"Wei","year":"2022","journal-title":"Acta Biochim. Biophys. Sin. Shanghai"},{"key":"10.1016\/j.lfs.2023.121804_bb0500","doi-asserted-by":"crossref","first-page":"2910","DOI":"10.1161\/ATVBAHA.120.314789","article-title":"Cell-type transcriptome atlas of human aortic valves reveal cell heterogeneity and endothelial to mesenchymal transition involved in calcific aortic valve disease","volume":"40","author":"Xu","year":"2020","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.lfs.2023.121804_bb0505","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/fcp.12229","article-title":"Advanced oxidation protein products induce apoptosis of human chondrocyte through reactive oxygen species-mediated mitochondrial dysfunction and endoplasmic reticulum stress pathways","volume":"31","author":"Ye","year":"2017","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1016\/j.lfs.2023.121804_bb0510","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.rdc.2010.03.004","article-title":"Innate immunity and rheumatoid arthritis","volume":"36","author":"Gierut","year":"2010","journal-title":"Rheum. Dis. Clin. N. Am."},{"key":"10.1016\/j.lfs.2023.121804_bb0515","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.semcdb.2016.05.009","article-title":"The joint synovium: a critical determinant of articular cartilage fate in inflammatory joint diseases","volume":"62","author":"Bhattaram","year":"2017","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.lfs.2023.121804_bb0520","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.yexcr.2005.11.012","article-title":"Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis","volume":"312","author":"Shibuya","year":"2006","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0525","first-page":"339","article-title":"Expression of basic fibroblast growth factor in synovial tissue from patients with rheumatoid arthritis and degenerative joint disease","volume":"73","author":"Qu","year":"1995","journal-title":"Lab. Investig."},{"key":"10.1016\/j.lfs.2023.121804_bb0530","doi-asserted-by":"crossref","first-page":"504","DOI":"10.3899\/jrheum.200673","article-title":"Circulating fibroblast growth Factor-21 levels in rheumatoid arthritis: associations with disease characteristics, body composition, and physical functioning","volume":"48","author":"Gould","year":"2021","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.lfs.2023.121804_bb0535","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/ar1203","article-title":"Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus","volume":"6","author":"Alarc\u00f3n-Riquelme","year":"2004","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.lfs.2023.121804_bb0540","doi-asserted-by":"crossref","first-page":"R230","DOI":"10.1186\/ar1467","article-title":"Rheumatoid arthritis synovium contains plasmacytoid dendritic cells","volume":"7","author":"Cavanagh","year":"2005","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.lfs.2023.121804_bb0545","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/jor.22263","article-title":"Silencing the expression of connexin 43 decreases inflammation and joint destruction in experimental arthritis","volume":"31","author":"Tsuchida","year":"2013","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0550","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2022.106270","article-title":"Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells","volume":"181","author":"Pan","year":"2022","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.lfs.2023.121804_bb0555","doi-asserted-by":"crossref","first-page":"55","DOI":"10.5606\/ArchRheumatol.2016.5597","article-title":"Expression of connexin 43 in synovial tissue of patients with rheumatoid arthritis","volume":"31","author":"Matsuki","year":"2016","journal-title":"Arch. Rheumatol."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320523004381?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320523004381?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:36:56Z","timestamp":1736383016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320523004381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":111,"alternative-id":["S0024320523004381"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2023.121804","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of fibroblast growth factor 7 in cartilage development and diseases","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2023.121804","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"121804"}}