{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:35:02Z","timestamp":1791920102664,"version":"4.3.4"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.lfs.2023.122380","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T11:50:25Z","timestamp":1703245825000},"page":"122380","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":54,"special_numbering":"C","title":["Bile acids metabolism in the gut-liver axis mediates liver injury during lactation"],"prefix":"10.1016","volume":"338","author":[{"given":"Long","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Zhuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianqiang","family":"Che","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengyu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengfeng","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xilun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lun","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.lfs.2023.122380_bb0005","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/S2213-8587(16)30217-0","article-title":"Preconceptional and maternal obesity: epidemiology and health consequences","volume":"4","author":"Poston","year":"2016","journal-title":"Lancet. Diab. Endocrinol."},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0010","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/MED.0b013e32834c800d","article-title":"Placental hormones and the control of maternal metabolism and fetal growth","volume":"18","author":"Newbern","year":"2011","journal-title":"Curr. Opin. Endocrinol. Diabetes Obes."},{"issue":"Suppl. 1","key":"10.1016\/j.lfs.2023.122380_bb0015","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1038\/sj.ejcn.1600984","article-title":"Metabolic adaptations in pregnancy and their implications for the availability of substrates to the fetus","volume":"54","author":"Herrera","year":"2000","journal-title":"Eur. J. Clin. Nutr."},{"issue":"48","key":"10.1016\/j.lfs.2023.122380_bb0020","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2107269118","article-title":"Pregnancy and weaning regulate human maternal liver size and function","volume":"118","author":"Bartlett, A.","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0025","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.celrep.2016.03.019","article-title":"An essential role for liver ER\u03b1 in coupling hepatic metabolism to the reproductive cycle","volume":"15","author":"Della Torre","year":"2016","journal-title":"Cell Rep."},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0030","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.195","article-title":"Time-restricted feeding improves the reproductive function of female mice via liver fibroblast growth factor 21","volume":"10","author":"Hua","year":"2020","journal-title":"Clin. Transl. Med."},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0035","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1136\/gut.51.6.876","article-title":"Prospective study of liver dysfunction in pregnancy in Southwest Wales","volume":"51","author":"Ch'ng","year":"2002","journal-title":"Gut"},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0040","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1080\/17474124.2020.1715210","article-title":"Fatty liver in pregnancy: a narrative review of two distinct conditions","volume":"14","author":"Azzaroli","year":"2020","journal-title":"Expert Rev. Gastroenterol. Hepatol."},{"issue":"5","key":"10.1016\/j.lfs.2023.122380_bb0045","doi-asserted-by":"crossref","first-page":"947","DOI":"10.14218\/JCTH.2022.00052","article-title":"Pregnancy and metabolic-associated fatty liver disease: a clinical update","volume":"10","author":"Fouda","year":"2022","journal-title":"J. Clin. Transl. Hepatol."},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0050","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jhep.2018.09.013","article-title":"Longer lactation duration is associated with decreased prevalence of non-alcoholic fatty liver disease in women","volume":"70","author":"Ajmera","year":"2019","journal-title":"J. Hepatol."},{"issue":"3","key":"10.1016\/j.lfs.2023.122380_bb0055","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.cell.2012.07.008","article-title":"Host remodeling of the gut microbiome and metabolic changes during pregnancy","volume":"150","author":"Koren","year":"2012","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0060","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s40168-021-01101-1","article-title":"Review: microbial transformations of human bile acids","volume":"9","author":"Guzior","year":"2021","journal-title":"Microbiome"},{"issue":"4","key":"10.1016\/j.lfs.2023.122380_bb0065","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/s42255-022-00559-z","article-title":"Metabolic messengers: bile acids","volume":"4","author":"Perino","year":"2022","journal-title":"Nat. Metab."},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0070","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1016\/j.tjnut.2023.04.012","article-title":"Time-restricted feeding ameliorates uterine epithelial estrogen receptor \u03b1 transcriptional activity at the time of embryo implantation in mice fed a high-fat diet","volume":"153","author":"Liu","year":"2023","journal-title":"J. Nutr."},{"issue":"3","key":"10.1016\/j.lfs.2023.122380_bb0075","doi-asserted-by":"crossref","first-page":"R69","DOI":"10.1530\/EJE-20-1101","article-title":"Endocrinology in pregnancy: metabolic impact of bile acids in gestation","volume":"184","author":"Fan","year":"2021","journal-title":"Eur. J. Endocrinol."},{"issue":"4","key":"10.1016\/j.lfs.2023.122380_bb0080","doi-asserted-by":"crossref","first-page":"G1009","DOI":"10.1152\/ajpgi.00017.2008","article-title":"Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat","volume":"294","author":"Wooton-Kee","year":"2008","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.lfs.2023.122380_bb0085","article-title":"Mechanisms for increased expression of cholesterol 7alpha-hydroxylase (Cyp7a1) in lactating rats","volume":"51(1):277-285","author":"Wooton-Kee","year":"2010","journal-title":"Hepatology (Baltimore, Md.)"},{"key":"10.1016\/j.lfs.2023.122380_bb0090","article-title":"Importance of the pig as a human biomedical model","volume":"13(621):eabd5758","author":"Lunney","year":"2021","journal-title":"Sci. Transl. Med."},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0095","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2527\/jas.2006-130","article-title":"Insulin sensitivity during pregnancy, lactation, and postweaning in primiparous gilts","volume":"85","author":"P\u00e8re","year":"2007","journal-title":"J. Anim. Sci."},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0100","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1128\/jb.173.2.697-703.1991","article-title":"16S ribosomal DNA amplification for phylogenetic study","volume":"173","author":"Weisburg","year":"1991","journal-title":"J. Bacteriol."},{"issue":"10","key":"10.1016\/j.lfs.2023.122380_bb0105","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1038\/nmeth.2604","article-title":"UPARSE: highly accurate OTU sequences from microbial amplicon reads","volume":"10","author":"Edgar","year":"2013","journal-title":"Nat. Methods"},{"issue":"11","key":"10.1016\/j.lfs.2023.122380_bb0110","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1038\/s42255-021-00493-6","article-title":"Lipolysis: cellular mechanisms for lipid mobilization from fat stores","volume":"3","author":"Grabner","year":"2021","journal-title":"Nat. Metab."},{"issue":"19","key":"10.1016\/j.lfs.2023.122380_bb0115","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21197097","article-title":"Prolonged lipid accumulation in cultured primary human hepatocytes rather leads to ER stress than oxidative stress","volume":"21","author":"Rennert","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.lfs.2023.122380_bb0120","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.stem.2016.01.002","article-title":"Bile acids protect expanding hematopoietic stem cells from unfolded protein stress in fetal liver","volume":"18","author":"Sigurdsson","year":"2016","journal-title":"Cell Stem Cell"},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0125","first-page":"443","article-title":"Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats","volume":"6","author":"Cummings","year":"2013","journal-title":"Dis. Model. Mech."},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0130","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.bbrc.2020.05.226","article-title":"Bile acids elevated by high-fat feeding induce endoplasmic reticulum stress in intestinal stem cells and contribute to mucosal barrier damage","volume":"529","author":"Huang","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0135","doi-asserted-by":"crossref","DOI":"10.1111\/apha.13861","article-title":"Obesogenic diet in mice compromises maternal metabolic physiology and lactation ability leading to reductions in neonatal viability","volume":"236","author":"Lean","year":"2022","journal-title":"Acta Physiol (Oxford)"},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0140","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1210\/en.2018-00057","article-title":"Impact of pregnancy and lactation on the long-term regulation of energy balance in female mice","volume":"159","author":"Ladyman","year":"2018","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0145","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.cell.2007.04.001","article-title":"The hormonal control of food intake","volume":"129","author":"Coll","year":"2007","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.lfs.2023.122380_bb0150","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1017\/S0022029905001299","article-title":"Lipid metabolism during lactation: a review of adipose tissue-liver interactions and the development of fatty liver","volume":"72","author":"Vernon","year":"2005","journal-title":"J. Dairy Res."},{"issue":"7","key":"10.1016\/j.lfs.2023.122380_bb0155","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1038\/s41591-018-0104-9","article-title":"Mechanisms of NAFLD development and therapeutic strategies","volume":"24","author":"Friedman","year":"2018","journal-title":"Nat. Med."},{"issue":"5","key":"10.1016\/j.lfs.2023.122380_bb0160","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1080\/1745039X.2015.1075670","article-title":"Effect of a negative energy balance induced by feed restriction on pro-inflammatory and endoplasmic reticulum stress signalling pathways in the liver and skeletal muscle of lactating sows","volume":"69","author":"Gessner","year":"2015","journal-title":"Arch. Anim. Nutr."},{"issue":"3","key":"10.1016\/j.lfs.2023.122380_bb0165","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.jhep.2003.11.006","article-title":"Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms","volume":"40","author":"Chiang","year":"2004","journal-title":"J. Hepatol."},{"issue":"2 Pt 1","key":"10.1016\/j.lfs.2023.122380_bb0170","first-page":"G293","article-title":"Hepatocellular protein kinase C activation by bile acids: implications for regulation of cholesterol 7 alpha-hydroxylase","volume":"271","author":"Stravitz","year":"1996","journal-title":"Am. J. Phys."},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0175","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/toxsci\/kfs248","article-title":"Repression of hepatobiliary transporters and differential regulation of classic and alternative bile acid pathways in mice during pregnancy","volume":"130","author":"Aleksunes","year":"2012","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.lfs.2023.122380_bb0180","article-title":"Enhanced microbial bile acid deconjugation and impaired Ileal uptake in pregnancy repress intestinal regulation of bile acid synthesis","volume":"70(1):276-293","author":"Ovadia","year":"2019","journal-title":"Hepatology (Baltimore, Md.)"},{"key":"10.1016\/j.lfs.2023.122380_bb0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.102766","article-title":"A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility","volume":"55","author":"Wei","year":"2020","journal-title":"EBioMedicine"},{"issue":"4","key":"10.1016\/j.lfs.2023.122380_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2020.11.017","article-title":"Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism","volume":"33","author":"Zheng","year":"2021","journal-title":"Cell Metab."},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0195","doi-asserted-by":"crossref","first-page":"E199","DOI":"10.1152\/ajpendo.00545.2003","article-title":"Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans","volume":"287","author":"Holst","year":"2004","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"10","key":"10.1016\/j.lfs.2023.122380_bb0200","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1172\/JCI21025","article-title":"Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c","volume":"113","author":"Watanabe","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.lfs.2023.122380_bb0205","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/164_2019_238","article-title":"The pharmacology of bile acids and their receptors","volume":"256","author":"Fiorucci","year":"2019","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.lfs.2023.122380_bb0210","article-title":"Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor","volume":"17(2):259-272","author":"Pineda Torra","year":"2003","journal-title":"Molec. Endocrinol."},{"issue":"39","key":"10.1016\/j.lfs.2023.122380_bb0215","doi-asserted-by":"crossref","first-page":"12550","DOI":"10.1021\/acs.jafc.2c05591","article-title":"Transcriptomic analysis reveals Lactobacillus reuteri alleviating alcohol-induced liver injury in mice by enhancing the Farnesoid X receptor signaling pathway","volume":"70","author":"Cheng","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.lfs.2023.122380_bb0220","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.biopha.2018.05.135","article-title":"Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice","volume":"105","author":"Yan","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"11","key":"10.1016\/j.lfs.2023.122380_bb0225","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202200636","article-title":"Bile acid alterations characterize the early onset and progression of nonalcoholic fatty liver disease in young mice fed with high fat and fructose diet","volume":"67","author":"Xiang","year":"2023","journal-title":"Mol. Nutr. Food Res."},{"issue":"8","key":"10.1016\/j.lfs.2023.122380_bb0230","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1111\/apt.17362","article-title":"Secondary bile acids improve risk prediction for non-invasive identification of mild liver fibrosis in nonalcoholic fatty liver disease","volume":"57","author":"Liu","year":"2023","journal-title":"Aliment. Pharmacol. Ther."},{"issue":"4","key":"10.1016\/j.lfs.2023.122380_bb0235","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/hep4.1490","article-title":"Bile acid changes associated with liver fibrosis and steatosis in the Mexican-American population of South Texas","volume":"4","author":"Kwan","year":"2020","journal-title":"Hepatol. Commun."},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0240","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.1073\/pnas.051551698","article-title":"The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity","volume":"98","author":"Staudinger","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0245","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s40168-023-01492-3","article-title":"Gut microbiome is linked to functions of peripheral immune cells in transition cows during excessive lipolysis","volume":"11","author":"Gu","year":"2023","journal-title":"Microbiome"},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0250","doi-asserted-by":"crossref","first-page":"14","DOI":"10.5152\/tjg.2018.17330","article-title":"Liver fibrosis","volume":"29","author":"Ayd\u0131n","year":"2018","journal-title":"Turk J Gastroenterol"},{"issue":"10\u221211","key":"10.1016\/j.lfs.2023.122380_bb0255","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1007\/s00011-022-01629-4","article-title":"Synergistic anti-inflammatory effect of gut microbiota and lithocholic acid on liver fibrosis","volume":"71","author":"Shao","year":"2022","journal-title":"Inflamm. Res."},{"issue":"36","key":"10.1016\/j.lfs.2023.122380_bb0260","doi-asserted-by":"crossref","first-page":"13580","DOI":"10.1073\/pnas.0804437105","article-title":"Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome","volume":"105","author":"Jones","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0265","doi-asserted-by":"crossref","first-page":"2208501","DOI":"10.1080\/19490976.2023.2208501","article-title":"Bacterial and metabolic phenotypes associated with inadequate response to ursodeoxycholic acid treatment in primary biliary cholangitis","volume":"15","author":"Martinez-Gili","year":"2023","journal-title":"Gut Microbes"},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0270","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.clnu.2023.03.022","article-title":"The gut microbiota-bile acid axis mediates the beneficial associations between plasma vitamin D and metabolic syndrome in Chinese adults: a prospective study","volume":"42","author":"Lin","year":"2023","journal-title":"Clin. Nutr."},{"issue":"3","key":"10.1016\/j.lfs.2023.122380_bb0275","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.1002\/jcb.27635","article-title":"Interaction of gut microbiota with dysregulation of bile acids in the pathogenesis of nonalcoholic fatty liver disease and potential therapeutic implications of probiotics","volume":"120","author":"Chen","year":"2019","journal-title":"J. Cell. Biochem."},{"issue":"Pt A","key":"10.1016\/j.lfs.2023.122380_bb0280","article-title":"Effect of lotus seed resistant starch on small intestinal flora and bile acids in hyperlipidemic rats","volume":"404","author":"Lei","year":"2023","journal-title":"Food Chem."},{"issue":"38","key":"10.1016\/j.lfs.2023.122380_bb0285","doi-asserted-by":"crossref","first-page":"12014","DOI":"10.1021\/acs.jafc.2c04817","article-title":"Nuciferine protects against high-fat diet-induced hepatic steatosis via modulation of gut microbiota and bile acid metabolism in rats","volume":"70","author":"Sun","year":"2022","journal-title":"J. Agric. Food Chem."},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0290","doi-asserted-by":"crossref","first-page":"23813","DOI":"10.1038\/s41598-021-03396-4","article-title":"Ileal microbial shifts after Roux-en-Y gastric bypass orchestrate changes in glucose metabolism through modulation of bile acids and L-cell adaptation","volume":"11","author":"Dang","year":"2021","journal-title":"Sci. Rep."},{"issue":"7122","key":"10.1016\/j.lfs.2023.122380_bb0295","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1038\/nature05414","article-title":"An obesity-associated gut microbiome with increased capacity for energy harvest","volume":"444","author":"Turnbaugh","year":"2006","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0300","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s12915-019-0699-4","article-title":"The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health","volume":"17","author":"Waters","year":"2019","journal-title":"BMC Biol."},{"issue":"8","key":"10.1016\/j.lfs.2023.122380_bb0305","doi-asserted-by":"crossref","first-page":"3390","DOI":"10.7150\/ijbs.69833","article-title":"Dynamics of the gut-liver axis in rats with varying fibrosis severity","volume":"18","author":"Xiang","year":"2022","journal-title":"Int. J. Biol. Sci."},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0310","doi-asserted-by":"crossref","first-page":"4234","DOI":"10.1016\/j.clnu.2021.01.031","article-title":"Fecal g. Streptococcus and g. Eubacterium_coprostanoligenes_group combined with sphingosine to modulate the serum dyslipidemia in high-fat diet mice","volume":"40","author":"Wei","year":"2021","journal-title":"Clin. Nutr."},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0315","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.celrep.2018.12.028","article-title":"Parabacteroides distasonis alleviates obesity and metabolic dysfunctions via production of succinate and secondary bile acids","volume":"26","author":"Wang","year":"2019","journal-title":"Cell Rep."},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0320","doi-asserted-by":"crossref","first-page":"3224","DOI":"10.1039\/C9FO00263D","article-title":"A sulfated polysaccharide from Gracilaria Lemaneiformis regulates cholesterol and bile acid metabolism in high-fat diet mice","volume":"10","author":"Huang","year":"2019","journal-title":"Food Funct."},{"key":"10.1016\/j.lfs.2023.122380_bb0325","doi-asserted-by":"crossref","first-page":"1189971","DOI":"10.3389\/fphar.2023.1189971","article-title":"Ameliorative effect of Aconite aqueous extract on diarrhea is associated with modulation of the gut microbiota and bile acid metabolism","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.lfs.2023.122380_bb0330","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1002\/hep.24279","article-title":"The contribution of endoplasmic reticulum stress to liver diseases","volume":"53","author":"Dara","year":"2011","journal-title":"Hepatology (Baltimore, Md.)"},{"issue":"6","key":"10.1016\/j.lfs.2023.122380_bb0335","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1038\/sj.emboj.7600596","article-title":"TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death","volume":"24","author":"Ohoka","year":"2005","journal-title":"EMBO J."},{"issue":"1","key":"10.1016\/j.lfs.2023.122380_bb0340","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1152\/physrev.00010.2008","article-title":"Role of bile acids and bile acid receptors in metabolic regulation","volume":"89","author":"Lefebvre","year":"2009","journal-title":"Physiol. Rev."},{"issue":"30","key":"10.1016\/j.lfs.2023.122380_bb0345","doi-asserted-by":"crossref","first-page":"26913","DOI":"10.1074\/jbc.M111.248203","article-title":"Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure","volume":"286","author":"Watanabe","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0350","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jcmgh.2016.11.006","article-title":"Endoplasmic reticulum stress regulates hepatic bile acid metabolism in mice","volume":"3","author":"Henkel","year":"2017","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"issue":"2","key":"10.1016\/j.lfs.2023.122380_bb0355","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3164\/jcbn.13-46","article-title":"The involvement of endoplasmic reticulum stress in bile acid-induced hepatocellular injury","volume":"54","author":"Adachi","year":"2014","journal-title":"J. Clin. Biochem. Nutr."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320523010159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320523010159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T21:14:20Z","timestamp":1758402860000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320523010159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":71,"alternative-id":["S0024320523010159"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2023.122380","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bile acids metabolism in the gut-liver axis mediates liver injury during lactation","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2023.122380","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"122380"}}