{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T21:15:27Z","timestamp":1787087727417,"version":"build-2736575974"},"reference-count":95,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["MCTIC 408503\/2018-1"],"award-info":[{"award-number":["MCTIC 408503\/2018-1"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["423594\/2018-4"],"award-info":[{"award-number":["423594\/2018-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["403194\/2023-7"],"award-info":[{"award-number":["403194\/2023-7"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["310413\/2023-0"],"award-info":[{"award-number":["310413\/2023-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["306733\/2023-4"],"award-info":[{"award-number":["306733\/2023-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["305093\/2017-7"],"award-info":[{"award-number":["305093\/2017-7"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["310331\/2020-0"],"award-info":[{"award-number":["310331\/2020-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88887.837841\/2023-00"],"award-info":[{"award-number":["88887.837841\/2023-00"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.lfs.2023.122408","type":"journal-article","created":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T15:23:22Z","timestamp":1704295402000},"page":"122408","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Prolonged testosterone 17\u03b2-cyclopentylpropionate exposition induces behavioral, ovarian, oviductal, uterine and reproductive disturbances in female mice"],"prefix":"10.1016","volume":"338","author":[{"given":"M\u00f4nica N.","family":"Barcelos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elda","family":"Gon\u00e7alves-Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus A.","family":"Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizi\u00e1ria C.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reggiani V.","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel Mauricio","family":"Castro-Gamero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00f4mulo D.","family":"Novaes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2023.122408_bb0005","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s12610-016-0029-4","article-title":"Anabolic steroids abuse and male infertility","volume":"26","author":"El Osta","year":"2016","journal-title":"Basic Clin. Androl."},{"key":"10.1016\/j.lfs.2023.122408_bb0010","series-title":"Textbook of Addiction Treatment","article-title":"Anabolic steroid use disorders: diagnosis and treatment","author":"Kanayama","year":"2021"},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0015","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3390\/healthcare9010097","article-title":"Adverse effects of anabolic-androgenic steroids: a literature review","volume":"9","author":"Albano","year":"2021","journal-title":"Healthcare"},{"key":"10.1016\/j.lfs.2023.122408_bb0020","series-title":"StatPearls [Internet]","first-page":"2023","author":"Middlebrook","year":"2022"},{"issue":"9","key":"10.1016\/j.lfs.2023.122408_bb0025","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1007\/s40279-017-0709-z","article-title":"Effects of anabolic androgenic steroids on the reproductive system of athletes and recreational users: a systematic review and meta-analysis","volume":"47","author":"Christou","year":"2017","journal-title":"Sports Med."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0030","doi-asserted-by":"crossref","first-page":"141","DOI":"10.5534\/wjmh.190002","article-title":"Management of anabolic steroid-induced infertility: novel strategies for fertility maintenance and recovery","volume":"38","author":"Tatem","year":"2020","journal-title":"World J. Mens. Health."},{"issue":"6","key":"10.1016\/j.lfs.2023.122408_bb0035","doi-asserted-by":"crossref","first-page":"367","DOI":"10.2165\/00007256-199622060-00005","article-title":"Psychological and behavioural effects of endogenous testosterone and anabolic-androgenic steroids. An update","volume":"22","author":"Bahrke","year":"1996","journal-title":"Sports Med."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0040","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1095\/biolreprod.102.008078","article-title":"Chronic administration of anabolic steroids disrupts pubertal onset and estrous cyclicity in rats","volume":"68","author":"Clark","year":"2003","journal-title":"Biol. Reprod."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0045","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0091-3057(95)02030-6","article-title":"Effects of prolonged exposure to anabolic steroids on the behavior of male and female mice","volume":"53","author":"Bronson","year":"1996","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"4 Pt 1","key":"10.1016\/j.lfs.2023.122408_bb0050","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1111\/j.1743-6109.2007.00469.x","article-title":"Exposure to an anabolic steroid changes female mice\u2019s sexual responses according to sex partner","volume":"4","author":"Barreto-Estrada","year":"2007","journal-title":"J. Sex. Med."},{"issue":"10","key":"10.1016\/j.lfs.2023.122408_bb0055","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1016\/j.psyneuen.2010.04.015","article-title":"Chronic anabolic androgenic steroid exposure alters corticotropin releasing factor expression and anxiety-like behaviors in the female mouse","volume":"35","author":"Costine","year":"2010","journal-title":"Psychoneuroendocrinology"},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0060","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.yhbeh.2014.04.008","article-title":"Sex and exercise interact to alter the expression of anabolic androgenic steroid-induced anxiety-like behaviors in the mouse","volume":"66","author":"Onakomaiya","year":"2014","journal-title":"Horm. Behav."},{"issue":"6","key":"10.1016\/j.lfs.2023.122408_bb0065","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1097\/WNR.0b013e32832a2393","article-title":"Enhanced fear responses in mice treated with anabolic androgenic steroids","volume":"20","author":"Agis-Balboa","year":"2009","journal-title":"Neuroreport"},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0070","doi-asserted-by":"crossref","first-page":"275","DOI":"10.5603\/FHC.2012.0037","article-title":"Stereological estimation of ovarian oocyte volume, surface area and number: application on mice treated with nandrolone decanoate","volume":"50","author":"Karbalay-Doust","year":"2012","journal-title":"Folia Histochem. Cytobiol."},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0075","doi-asserted-by":"crossref","DOI":"10.4322\/hra.001417","article-title":"Uterine morphological changes induced by androgenic anabolic steroids","volume":"32","author":"Silva","year":"2017","journal-title":"Hum. Reprod. Arch."},{"issue":"5","key":"10.1016\/j.lfs.2023.122408_bb0080","first-page":"032","article-title":"Anabolic-androgenic steroid (stanozolol) disrupts ovarian histoarchitecture and gestation in mice","volume":"4","author":"Jayamma","year":"2012","journal-title":"Int. J. Curr. Res."},{"key":"10.1016\/j.lfs.2023.122408_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.steroids.2020.108752","article-title":"High, not low-dose of stanozolol (Anabolic - androgenic steroid) impedes embryo implantation by attenuating endometrial receptivity in the mouse, Mus musculus","volume":"165","author":"Sharma","year":"2021","journal-title":"Steroids"},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0090","first-page":"159","article-title":"The non-preventive effects of human menopausal gonadotropins on ovarian tissues in nandrolone decanoate-treated female rats: a histochemical and ultra-structural study","volume":"16","author":"Mesbah","year":"2018","journal-title":"Int. J. Reprod. Biomed."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0095","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/bdrb.20106","article-title":"The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies","volume":"80","author":"Goldman","year":"2007","journal-title":"Birth Defects Res. B Dev. Reprod. Toxicol."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0100","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1002\/bdrb.21104","article-title":"Dose-dependent effects and reversibility of the injuries caused by nandrolone decanoate in uterine tissue and fertility of rats","volume":"101","author":"Belardin","year":"2014","journal-title":"Birth Defects Res. B Dev. Reprod. Toxicol."},{"key":"10.1016\/j.lfs.2023.122408_bb0105","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.reprotox.2021.05.002","article-title":"Nandrolone decanoate causes uterine injury by changing hormone levels and sex steroid receptors in a dose- and time-dependent manner","volume":"102","author":"Sim\u00e3o","year":"2021","journal-title":"Reprod. Toxicol."},{"issue":"6","key":"10.1016\/j.lfs.2023.122408_bb0110","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1080\/10520295.2020.1822545","article-title":"Immunohistochemical and histophysiological study of prolonged use of nandrolone on reproductive organs and fertility","volume":"96","author":"Santos","year":"2021","journal-title":"Biotech. Histochem."},{"key":"10.1016\/j.lfs.2023.122408_bb0115","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.neubiorev.2019.02.014","article-title":"Supraphysiologic-dose anabolic-androgenic steroid use: a risk factor for dementia?","volume":"100","author":"Kaufman","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0120","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.yhbeh.2009.09.006","article-title":"Illicit anabolic-androgenic steroid use","volume":"58","author":"Kanayama","year":"2010","journal-title":"Horm. Behav."},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0125","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0031-9384(95)02027-6","article-title":"Effect of anabolic steroids on behavior and physiological characteristics of female mice","volume":"59","author":"Bronson","year":"1996","journal-title":"Physiol. Behav."},{"issue":"9","key":"10.1016\/j.lfs.2023.122408_bb0130","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.jpain.2018.04.002","article-title":"Nonlinear inverted-U shaped relationship between aging and epidermal innervation in the rat plantar hind paw: a laser scanning confocal microscopy study","volume":"19","author":"Kaliappan","year":"2018","journal-title":"J. Pain"},{"issue":"40","key":"10.1016\/j.lfs.2023.122408_bb0135","doi-asserted-by":"crossref","first-page":"12484","DOI":"10.1523\/JNEUROSCI.3108-09.2009","article-title":"Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms","volume":"29","author":"Penatti","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.lfs.2023.122408_bb0140","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1743-1050-3-2","article-title":"Comparative analysis of follicle morphology and oocyte diameter in four mammalian species (mouse, hamster, pig, and human)","volume":"3","author":"Griffin","year":"2006","journal-title":"J. Exp. Clin. Assist. Reprod."},{"issue":"5","key":"10.1016\/j.lfs.2023.122408_bb0145","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1530\/REP-16-0233","article-title":"Ovarian sex steroid receptors and sex hormones in androgenized rats","volume":"152","author":"Sim\u00e3o","year":"2016","journal-title":"Reproduction"},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0150","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1530\/jrf.0.0170555","article-title":"Proposal for a classification of oocytes and follicles in the mouse ovary","volume":"17","author":"Pedersen","year":"1968","journal-title":"J. Reprod. Fertil."},{"issue":"7","key":"10.1016\/j.lfs.2023.122408_bb0155","doi-asserted-by":"crossref","first-page":"3557","DOI":"10.3390\/ijms22073557","article-title":"Pseudo-starvation driven energy expenditure negatively affects ovarian follicle development","volume":"22","author":"Meng","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0160","doi-asserted-by":"crossref","DOI":"10.1111\/aji.13247","article-title":"Amoxicillin-induced gut dysbiosis influences estrous cycle in mice and cytokine expression in the ovary and the caecum","volume":"84","author":"Silva","year":"2020","journal-title":"Am. J. Reprod. Immunol."},{"issue":"5","key":"10.1016\/j.lfs.2023.122408_bb0165","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1093\/molehr\/gar025","article-title":"Regulation of division in mammalian oocytes: implications for polar body formation","volume":"17","author":"Levi","year":"2011","journal-title":"Mol. Hum. Reprod."},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0170","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1590\/S1519-69842009000100020","article-title":"Development and reproductive performance of Swiss mice in an enriched environment","volume":"69","author":"Carvalho","year":"2009","journal-title":"Braz. J. Biol."},{"key":"10.1016\/j.lfs.2023.122408_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2020.111560","article-title":"Perinatal exposure to glyphosate or a glyphosate-based formulation disrupts hormonal and uterine milieu during the receptive state in rats","volume":"143","author":"Lorenz","year":"2020","journal-title":"Food Chem. Toxicol."},{"issue":"50","key":"10.1016\/j.lfs.2023.122408_bb0180","doi-asserted-by":"crossref","first-page":"36755","DOI":"10.1074\/jbc.M705143200","article-title":"Activin regulates estrogen receptor gene expression in the mouse ovary","volume":"282","author":"Kipp","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2023.122408_bb0185","series-title":"Comprehensive Human Physiology","article-title":"Hormonal regulation of reproductive organs","author":"Weinbauer","year":"1996"},{"issue":"10","key":"10.1016\/j.lfs.2023.122408_bb0190","doi-asserted-by":"crossref","DOI":"10.1111\/and.13730","article-title":"Androgen effect on body weight and behaviour of male and female rats: novel insight on the clinical value","volume":"52","author":"Alrabadi","year":"2020","journal-title":"Andrologia"},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0195","doi-asserted-by":"crossref","first-page":"319","DOI":"10.2466\/pms.1999.88.1.319","article-title":"Lack of effects of anabolic-androgenic steroids on locomotor activity in intact male mice","volume":"88","author":"Salvador","year":"1999","journal-title":"Percept. Mot. Skills"},{"issue":"1\u20132","key":"10.1016\/j.lfs.2023.122408_bb0200","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/0006-8993(93)90823-6","article-title":"Up-regulation of androgen receptor immunoreactivity in the rat brain by androgenic-anabolic steroids","volume":"622","author":"Menard","year":"1993","journal-title":"Brain Res."},{"issue":"5","key":"10.1016\/j.lfs.2023.122408_bb0205","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0149-7634(03)00064-2","article-title":"Behavioral and physiological responses to anabolic-androgenic steroids","volume":"27","author":"Clark","year":"2003","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0210","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1046\/j.0953-816X.2000.01402.x","article-title":"The anabolic-androgenic steroid nandrolone decanoate affects the density of dopamine receptors in the male rat brain","volume":"13","author":"Kindlundh","year":"2001","journal-title":"Eur. J. Neurosci."},{"issue":"4","key":"10.1016\/j.lfs.2023.122408_bb0215","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0028-3908(02)00154-5","article-title":"Anabolic androgenic steroids induce age-, sex, and dose-dependent changes in GABA(A) receptor subunit mRNAs in the mouse forebrain","volume":"43","author":"McIntyre","year":"2002","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0220","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0149-7634(98)00040-2","article-title":"Neuropharmacology of brain-stimulation-evoked aggression","volume":"23","author":"Siegel","year":"1999","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0225","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/S0091-3057(02)00880-8","article-title":"Serotonin modulates offensive attack in adolescent anabolic steroid-treated hamsters","volume":"73","author":"Grimes","year":"2002","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0230","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.pbb.2011.04.023","article-title":"Anabolic-androgenic steroid effects on nociception and morphine antinociception in male rats","volume":"99","author":"Tsutsui","year":"2011","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"7","key":"10.1016\/j.lfs.2023.122408_bb0235","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.jpain.2018.02.007","article-title":"Opposing roles of estradiol and testosterone on stress-induced visceral hypersensitivity in rats","volume":"19","author":"Ji","year":"2018","journal-title":"J. Pain"},{"issue":"12","key":"10.1016\/j.lfs.2023.122408_bb0240","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1097\/j.pain.0000000000001985","article-title":"Testosterone protects against the development of widespread muscle pain in mice","volume":"161","author":"Lesnak","year":"2020","journal-title":"Pain"},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0245","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.neuroscience.2005.08.039","article-title":"Anabolic androgenic steroids and forebrain GABAergic transmission","volume":"138","author":"Henderson","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.lfs.2023.122408_bb0250","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.neuroscience.2018.06.012","article-title":"Spinal inhibition of P2XR or p38 signaling disrupts hyperalgesic priming in male, but not female, mice","volume":"385","author":"Paige","year":"2018","journal-title":"Neuroscience"},{"issue":"8","key":"10.1016\/j.lfs.2023.122408_bb0255","doi-asserted-by":"crossref","first-page":"4142","DOI":"10.1210\/en.2008-0183","article-title":"The androgen receptor is selectively involved in organization of sexually dimorphic social behaviors in mice","volume":"149","author":"Bodo","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.lfs.2023.122408_bb0260","doi-asserted-by":"crossref","first-page":"1059473","DOI":"10.3389\/fendo.2022.1059473","article-title":"Anabolic-androgenic steroids: how do they work and what are the risks?","volume":"13","author":"Bond","year":"2022","journal-title":"Front. Endocrinol."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0265","doi-asserted-by":"crossref","first-page":"R47","DOI":"10.1530\/EJE-15-0080","article-title":"Mechanisms in endocrinology: medical consequences of doping with anabolic androgenic steroids: effects on reproductive functions","volume":"173","author":"Nieschlag","year":"2015","journal-title":"Eur. J. Endocrinol."},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0270","first-page":"44","article-title":"Modulatory effect of gonadotropins on rats\u2019 ovaries after nandrolone decanoate administration: a stereological study","volume":"39","author":"Bordbar","year":"2014","journal-title":"Iran J. Med. Sci."},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0275","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/smrj.53","article-title":"Testosterone therapy for female sexual dysfunction","volume":"3","author":"Khera","year":"2015","journal-title":"Sex Med. Rev."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0280","first-page":"95","article-title":"Extragonadal synthesis of sex steroids: intracrinology","volume":"64","author":"Labrie","year":"2003","journal-title":"Ann. Endocrinol."},{"key":"10.1016\/j.lfs.2023.122408_bb0285","series-title":"The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use","year":"2020"},{"issue":"14","key":"10.1016\/j.lfs.2023.122408_bb0290","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1097\/01.wnr.0000234752.03808.b2","article-title":"Neurosteroids regulate mouse aggression induced by anabolic androgenic steroids","volume":"17","author":"Pibiri","year":"2006","journal-title":"Neuroreport"},{"issue":"6","key":"10.1016\/j.lfs.2023.122408_bb0295","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1073\/pnas.0409643102","article-title":"Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior","volume":"102","author":"Pinna","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0300","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1210\/en.2011-1674","article-title":"Anxiolytic effects and neuroanatomical targets of estrogen receptor-\u03b2 (ER\u03b2) activation by a selective ER\u03b2 agonist in female mice","volume":"153","author":"Oyola","year":"2012","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0305","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.bbr.2008.09.016","article-title":"Proestrous compared to diestrous wildtype, but not estrogen receptor beta knockout, mice have better performance in the spontaneous alternation and object recognition tasks and reduced anxiety-like behavior in the elevated plus and mirror maze","volume":"196","author":"Walf","year":"2009","journal-title":"Behav. Brain Res."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0310","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/0091-3057(93)90260-Z","article-title":"Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABAA receptor function","volume":"45","author":"Bitran","year":"1993","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0315","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.neuropharm.2004.09.002","article-title":"Anxiolytic activity of progesterone in progesterone receptor knockout mice","volume":"48","author":"Reddy","year":"2005","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.lfs.2023.122408_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugpo.2020.102876","article-title":"Anabolic-androgenic steroid use among women - a qualitative study on experiences of masculinizing, gonadal and sexual effects","volume":"95","author":"Havnes","year":"2021","journal-title":"Int. J. Drug Policy"},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0325","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0165-6147(93)90032-F","article-title":"Current perspectives on anabolic-androgenic steroid abuse","volume":"14","author":"Lukas","year":"1993","journal-title":"Trends Pharmacol. Sci."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0330","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0031-9384(96)00409-X","article-title":"The effects of 17 alpha-methyltestosterone, methandrostenolone, and nandrolone decanoate on the rat estrous cycle","volume":"61","author":"Blasberg","year":"1997","journal-title":"Physiol. Behav."},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0335","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1556\/ABiol.60.2009.3.2","article-title":"Ovarian histology and follicular score in female rats treated with nandrolone decanoate and submitted to physical effort","volume":"60","author":"Cherici Camargo","year":"2009","journal-title":"Acta Biol. Hung."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0340","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ejogrb.2006.07.037","article-title":"Administration of the anabolic androgenic steroid nandrolone decanoate to female rats causes alterations in the morphology of their uterus and a reduction in reproductive capacity","volume":"131","author":"Mobini Far","year":"2007","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"7","key":"10.1016\/j.lfs.2023.122408_bb0345","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/0039-128X(94)00036-C","article-title":"A decreasing CD4+\/CD8+ ratio after one month of treatment with stanazolol in postmenopausal women","volume":"60","author":"Zofkov\u00e1","year":"1995","journal-title":"Steroids"},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb0350","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0031-9384(97)00443-5","article-title":"Stanozolol, oxymetholone, and testosterone cypionate effects on the rat estrous cycle","volume":"63","author":"Clark","year":"1998","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.lfs.2023.122408_bb0355","series-title":"Anabolics","first-page":"739","article-title":"Part III: Drug profiles","author":"Llewellyn","year":"2011"},{"issue":"4","key":"10.1016\/j.lfs.2023.122408_bb0360","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1210\/jc.2016-1271","article-title":"Compounded bioidentical hormones in endocrinology practice: an endocrine society scientific statement","volume":"101","author":"Santoro","year":"2016","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0365","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1055\/s-2002-35374","article-title":"The essential role of the aromatase\/p450arom","volume":"20","author":"Meinhardt","year":"2002","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.lfs.2023.122408_bb0370","series-title":"Doping in Sports: Biochemical Principles, Effects and Analysis. Handbook of Experimental Pharmacology","article-title":"Side effects of anabolic androgenic steroids: Pathological findings and structure\u2013activity relationships","volume":"vol. 195","author":"B\u00fcttner","year":"2010"},{"issue":"4","key":"10.1016\/j.lfs.2023.122408_bb0375","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.neuropharm.2011.05.008","article-title":"Chronic exposure to anabolic androgenic steroids alters activity and synaptic function in neuroendocrine control regions of the female mouse","volume":"61","author":"Penatti","year":"2011","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0380","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090451","article-title":"Characterization of aromatase expression in the adult male and female mouse brain. I. Coexistence with oestrogen receptors \u03b1 and \u03b2, and androgen receptors","volume":"9","author":"Stani\u0107","year":"2014","journal-title":"PloS One"},{"issue":"6","key":"10.1016\/j.lfs.2023.122408_bb0385","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/j.1365-2826.2008.01713.x","article-title":"Aromatase in the brain: not just for reproduction anymore","volume":"20","author":"Garcia-Segura","year":"2008","journal-title":"J. Neuroendocrinol."},{"issue":"33","key":"10.1016\/j.lfs.2023.122408_bb0390","doi-asserted-by":"crossref","first-page":"12435","DOI":"10.1073\/pnas.0603006103","article-title":"Follicle-stimulating hormone\/cAMP regulation of aromatase gene expression requires beta-catenin","volume":"103","author":"Parakh","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5","key":"10.1016\/j.lfs.2023.122408_bb0395","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.steroids.2008.01.017","article-title":"Aromatase expression in the ovary: hormonal and molecular regulation","volume":"73","author":"Stocco","year":"2008","journal-title":"Steroids"},{"issue":"5","key":"10.1016\/j.lfs.2023.122408_bb0400","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/iep.12144","article-title":"Effects of different doses of nandrolone decanoate on estrous cycle and ovarian tissue of rats after treatment and recovery periods","volume":"96","author":"Sim\u00e3o","year":"2015","journal-title":"Int. J. Exp. Pathol."},{"issue":"4","key":"10.1016\/j.lfs.2023.122408_bb0405","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.etp.2014.01.005","article-title":"Histopathologycal findings in the ovaries and uterus of albino female rats promoted by co-administration of synthetic steroids and nicotine","volume":"66","author":"Camargo","year":"2014","journal-title":"Exp. Toxicol. Pathol."},{"issue":"10","key":"10.1016\/j.lfs.2023.122408_bb0410","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1002\/jat.1701","article-title":"Nandrolone androgenic hormone presents genotoxic effects in different cells of mice","volume":"32","author":"do Carmo","year":"2012","journal-title":"J. Appl. Toxicol."},{"issue":"4","key":"10.1016\/j.lfs.2023.122408_bb0415","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0015-0282(00)00711-1","article-title":"Do androgens have a direct effect on endometrial function? An in vitro study","volume":"74","author":"Tuckerman","year":"2000","journal-title":"Fertil. Steril."},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0420","first-page":"163","article-title":"Nandrolone decanoate causes pathologic changes in the uterus of surgically postmenopausal female cynomolgus macaques","volume":"5","author":"Obasanjo","year":"1998","journal-title":"Menopause"},{"issue":"18","key":"10.1016\/j.lfs.2023.122408_bb0425","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1101\/gad.9.18.2266","article-title":"Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities","volume":"9","author":"Lydon","year":"1995","journal-title":"Genes Dev."},{"issue":"3","key":"10.1016\/j.lfs.2023.122408_bb0430","doi-asserted-by":"crossref","first-page":"328","DOI":"10.3181\/00379727-183-42426","article-title":"Effects of dihydrotestosterone on progesterone secretion in pseudopregnant rats","volume":"183","author":"Sridaran","year":"1986","journal-title":"Proc. Soc. Exp. Biol. Med."},{"issue":"1","key":"10.1016\/j.lfs.2023.122408_bb0435","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1093\/humrep\/deh543","article-title":"Falling estradiol levels as a result of intentional reduction in gonadotrophin dose are not associated with poor IVF outcomes, whereas spontaneously falling estradiol levels result in low clinical pregnancy rates","volume":"20","author":"Fisher","year":"2005","journal-title":"Hum. Reprod."},{"issue":"9","key":"10.1016\/j.lfs.2023.122408_bb0440","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1242\/dev.122.9.2687","article-title":"Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression","volume":"122","author":"Benson","year":"1996","journal-title":"Development"},{"issue":"6390","key":"10.1016\/j.lfs.2023.122408_bb0445","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/359076a0","article-title":"Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor","volume":"359","author":"Stewart","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.lfs.2023.122408_bb2000","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.116603","article-title":"Trans-fatty acids aggravate anabolic steroid-induced metabolic disturbances and differential gene expression in muscle, pancreas and adipose tissue","volume":"232","author":"Gon\u00e7alves","year":"2019","journal-title":"Life Sci."},{"issue":"Pt B","key":"10.1016\/j.lfs.2023.122408_bb2005","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.fct.2018.04.056","article-title":"Food-drug interaction: Anabolic steroids aggravate hepatic lipotoxicity and nonalcoholic fatty liver disease induced by trans fatty acids","volume":"116","author":"Santos","year":"2018","journal-title":"Food. Chem. Toxicol."},{"key":"10.1016\/j.lfs.2023.122408_bb2010","doi-asserted-by":"crossref","unstructured":"A.W. Bannon, A.B. Malmberg. Models of nociception: hot-plate, tail-flick, and formalin tests in rodents. Curr. Protoc. Neurosci. 2007;Chapter 8:Unit 8.9.","DOI":"10.1002\/0471142301.ns0809s41"},{"key":"10.1016\/j.lfs.2023.122408_bb2015","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.exger.2018.01.022","article-title":"Could age and aging change the host response to systemic parasitic infections? A systematic review of preclinical evidence","volume":"104","author":"Felizardo","year":"2018","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.lfs.2023.122408_bb2020","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.actatropica.2017.02.012","article-title":"Parasite control and skeletal myositis in Trypanosoma cruzi-infected and exercised rats","volume":"170","author":"Novaes","year":"2017","journal-title":"Acta Trop."},{"issue":"2","key":"10.1016\/j.lfs.2023.122408_bb2025","doi-asserted-by":"crossref","DOI":"10.1111\/iep.12183","article-title":"Acute paraquat exposure determines dose-dependent oxidative injury of multiple organs and metabolic dysfunction in rats: impact on exercise tolerance","volume":"97","author":"Novaes","year":"2016","journal-title":"Int. J. Exp. Pathol."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320523010433?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320523010433?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:03:54Z","timestamp":1777388634000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320523010433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":95,"alternative-id":["S0024320523010433"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2023.122408","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prolonged testosterone 17\u03b2-cyclopentylpropionate exposition induces behavioral, ovarian, oviductal, uterine and reproductive disturbances in female mice","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2023.122408","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"122408"}}