{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:43:13Z","timestamp":1789623793496,"version":"build-2803163510"},"reference-count":126,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.lfs.2024.122777","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T15:32:42Z","timestamp":1717687962000},"page":"122777","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Toxin-derived peptides: An unconventional approach to alleviating cerebral stroke burden and neurobehavioral impairments"],"prefix":"10.1016","volume":"351","author":[{"given":"Sayed Md","family":"Mumtaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Ahmed","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azfar","family":"Jamal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaheenkousar H.","family":"Hattiwale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suhel","family":"Parvez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2024.122777_bb0005","doi-asserted-by":"crossref","first-page":"4749","DOI":"10.2174\/0929867325666181031122438","article-title":"Animal venom peptides as a treasure trove for new therapeutics against neurodegenerative disorders","volume":"26","author":"Yang","year":"2018","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.lfs.2024.122777_bb0010","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1055\/s-0038-1649503","article-title":"Global burden of stroke","volume":"38","author":"Katan","year":"2018","journal-title":"Semin. Neurol."},{"key":"10.1016\/j.lfs.2024.122777_bb0015","doi-asserted-by":"crossref","DOI":"10.1186\/s43094-021-00289-1","article-title":"Cerebral ischemic stroke and different approaches for treatment of stroke","volume":"7","author":"Girnar","year":"2021","journal-title":"Futur. J. Pharm. Sci."},{"issue":"7","key":"10.1016\/j.lfs.2024.122777_bb0020","first-page":"1","article-title":"Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions","volume":"71","author":"Qin","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.lfs.2024.122777_bb0025","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s40478-016-0371-y","article-title":"Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue","volume":"4","author":"Nguyen","year":"2016","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.lfs.2024.122777_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2018.09.012","article-title":"Current advances in ischemic stroke research and therapies","volume":"1866","author":"Barthels","year":"2020","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.lfs.2024.122777_bb0035","doi-asserted-by":"crossref","unstructured":"K. de C.F. Bordon, C.T. Cologna, E.C. Fornari-Baldo, E.L. Pinheiro-J\u00fanior, F.A. Cerni, F.G. Amorim, F.A.P. Anjolette, F.A. Cordeiro, G.A. Wiezel, I.A. Cardoso, I.G. Ferreira, I.S. de Oliveira, J. Boldrini-Fran\u00e7a, M.B. Pucca, M.A. Baldo, E.C. Arantes, From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery, Front. Pharmacol. 11 (2020) 1132. doi:https:\/\/doi.org\/10.3389\/FPHAR.2020.01132.","DOI":"10.3389\/fphar.2020.01132"},{"key":"10.1016\/j.lfs.2024.122777_bb0040","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1080\/14789450.2017.1377613","article-title":"Venom peptides as therapeutics: advances, challenges and the future of venom-peptide discovery","volume":"14","author":"Robinson","year":"2017","journal-title":"Expert Rev. Proteomics"},{"key":"10.1016\/j.lfs.2024.122777_bb0045","doi-asserted-by":"crossref","first-page":"19122","DOI":"10.1021\/acsomega.1c07016","article-title":"Pregnenolone attenuates the ischemia-induced neurological deficit in the transient middle cerebral artery occlusion model of rats","volume":"7","author":"Andrabi","year":"2022","journal-title":"ACS Omega"},{"key":"10.1016\/j.lfs.2024.122777_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2020.114096","article-title":"Animal toxins - nature\u2019s evolutionary-refined toolkit for basic research and drug discovery","volume":"181","author":"Herzig","year":"2020","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.lfs.2024.122777_bb0055","doi-asserted-by":"crossref","first-page":"2927","DOI":"10.2174\/138161207782023739","article-title":"Approaching the golden age of natural product pharmaceuticals from venom libraries: an overview of toxins and toxin-derivatives currently involved in therapeutic or diagnostic applications","volume":"13","author":"Fox","year":"2007","journal-title":"Curr. Pharm. Des."},{"issue":"4","key":"10.1016\/j.lfs.2024.122777_bb0060","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s41048-018-0067-x","article-title":"Animal protein toxins: origins and therapeutic applications","volume":"45","author":"Chen","year":"2018","journal-title":"Biophys. Rep."},{"key":"10.1016\/j.lfs.2024.122777_bb0065","doi-asserted-by":"crossref","unstructured":"K. de C.F. Bordon, C.T. Cologna, E.C. Fornari-Baldo, E.L. Pinheiro-J\u00fanior, F.A. Cerni, F.G. Amorim, F.A.P. Anjolette, F.A. Cordeiro, G.A. Wiezel, I.A. Cardoso, I.G. Ferreira, I.S. de Oliveira, J. Boldrini-Fran\u00e7a, M.B. Pucca, M.A. Baldo, E.C. Arantes, From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery, Front. Pharmacol. 11 (2020) 553397. doi:https:\/\/doi.org\/10.3389\/FPHAR.2020.01132\/BIBTEX.","DOI":"10.3389\/fphar.2020.01132"},{"key":"10.1016\/j.lfs.2024.122777_bb0070","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2019.00423","article-title":"Editorial: animal toxins as comprehensive pharmacological tools to identify diverse ion channels","volume":"10","author":"Utkin","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.lfs.2024.122777_bb0075","article-title":"Venoms as an adjunctive therapy for Parkinson\u2019s disease: where are we now and where are we going?","volume":"7","author":"Gazerani","year":"2020","journal-title":"Future Sci. OA"},{"key":"10.1016\/j.lfs.2024.122777_bb0080","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1001\/jamaneurol.2018.1264","article-title":"Current concepts in diagnosis and treatment of functional neurological disorders","volume":"75","author":"Espay","year":"2018","journal-title":"JAMA Neurol."},{"issue":"8","key":"10.1016\/j.lfs.2024.122777_bb0085","first-page":"1","article-title":"Therapeutic potential of venom peptides: insights in the nanoparticle-mediated venom formulations","volume":"81","author":"Joglekar","year":"2022","journal-title":"Futur. J. Pharm. Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0090","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.3233\/JAD-201146","article-title":"Metabotropic glutamate receptors in Alzheimer\u2019s disease synaptic dysfunction: therapeutic opportunities and hope for the future","volume":"78","author":"Srivastava","year":"2020","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.lfs.2024.122777_bb0095","doi-asserted-by":"crossref","DOI":"10.1159\/000232592","article-title":"Drug development: from concept to marketing!","volume":"113","author":"Tamimi","year":"2009","journal-title":"Nephron Clin. Pract."},{"key":"10.1016\/j.lfs.2024.122777_bb0100","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s10989-018-9721-x","article-title":"Scorpion venom\u2013toxins that aid in drug development: a review","volume":"25","author":"Ghosh","year":"2019","journal-title":"Int. J. Pept. Res. Ther."},{"key":"10.1016\/j.lfs.2024.122777_bb0105","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/B978-0-12-394309-5.00006-7","article-title":"Cell biology of ischemia\/reperfusion injury","volume":"298","author":"Kalogeris","year":"2012","journal-title":"Int. Rev. Cell Mol. Biol."},{"key":"10.1016\/j.lfs.2024.122777_bb0110","doi-asserted-by":"crossref","first-page":"4749","DOI":"10.2174\/0929867325666181031122438","article-title":"Animal venom peptides as a treasure trove for New therapeutics against neurodegenerative disorders","volume":"26","author":"Yang","year":"2019","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.lfs.2024.122777_bb0115","doi-asserted-by":"crossref","first-page":"948","DOI":"10.7150\/ijbs.6426","article-title":"Glutamate, glutamate receptors, and downstream signaling pathways","volume":"9","author":"Willard","year":"2013","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0120","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.neuron.2015.05.041","article-title":"Novel stroke therapeutics: unraveling stroke pathophysiology and its impact on clinical treatments","volume":"87","author":"George","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.lfs.2024.122777_bb0125","article-title":"Interleukins and ischemic stroke","volume":"13","author":"Zhu","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.lfs.2024.122777_bb0130","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1007\/s12264-022-00859-0","article-title":"Neuronal death mechanisms and therapeutic strategy in ischemic stroke","volume":"38","author":"Mao","year":"2022","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.lfs.2024.122777_bb0135","first-page":"C33","article-title":"The role of proteases in excitation-contraction coupling failure in muscular dystrophy","volume":"308","author":"M\u00e1zala","year":"2015","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.lfs.2024.122777_bb0140","doi-asserted-by":"crossref","DOI":"10.3389\/fncir.2021.711564","article-title":"Calcium permeable-AMPA receptors and excitotoxicity in neurological disorders","volume":"15","author":"Guo","year":"2021","journal-title":"Front. Neural Circuits."},{"key":"10.1016\/j.lfs.2024.122777_bb0145","doi-asserted-by":"crossref","first-page":"9330","DOI":"10.1523\/JNEUROSCI.2212-09.2009","article-title":"Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP","volume":"29","author":"Xu","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.lfs.2024.122777_bb0150","doi-asserted-by":"crossref","first-page":"924","DOI":"10.14336\/AD.2017.1126","article-title":"Mitochondria in ischemic stroke: new insight and implications","volume":"9","author":"Liu","year":"2018","journal-title":"Aging Dis."},{"key":"10.1016\/j.lfs.2024.122777_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2018.e00976","article-title":"Up-regulation of GluN2A-containing NMDA receptor protects cultured cortical neuron cells from oxidative stress","volume":"4","author":"Zhu","year":"2018","journal-title":"Heliyon"},{"key":"10.1016\/j.lfs.2024.122777_bb0160","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.apsb.2019.10.003","article-title":"Targeting autophagy-related protein kinases for potential therapeutic purpose","volume":"10","author":"Xiang","year":"2020","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.lfs.2024.122777_bb0165","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0960-9822(06)00122-9","article-title":"Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha","volume":"7","author":"Alessi","year":"1997","journal-title":"Curr. Biol."},{"key":"10.1016\/j.lfs.2024.122777_bb0170","doi-asserted-by":"crossref","first-page":"26596","DOI":"10.1074\/jbc.273.41.26596","article-title":"N-methyl-D-aspartate inhibits apoptosis through activation of phosphatidylinositol 3-kinase in cerebellar granule neurons. A role for insulin receptor substrate-1 in the neurotrophic action of n-methyl-D-aspartate and its inhibition by ethanol","volume":"273","author":"Zhang","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2024.122777_bb0175","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202002308RR","article-title":"Slack K+ channels attenuate NMDA-induced excitotoxic brain damage and neuronal cell death","volume":"35","author":"Ehinger","year":"2021","journal-title":"FASEB J."},{"key":"10.1016\/j.lfs.2024.122777_bb0180","doi-asserted-by":"crossref","first-page":"5391","DOI":"10.12659\/MSM.910191","article-title":"SC79, the AKT activator protects cerebral ischemia in a rat model of ischemia\/reperfusion injury","volume":"24","author":"Luan","year":"2018","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.lfs.2024.122777_bb0185","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1038\/sj.jcbfm.9600303","article-title":"Activation of the Akt\/GSK3beta signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats","volume":"26","author":"Endo","year":"2006","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.lfs.2024.122777_bb0190","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1097\/00004647-200111000-00003","article-title":"Neuroprotective effect of sodium orthovanadate on delayed neuronal death after transient forebrain ischemia in gerbil hippocampus","volume":"21","author":"Kawano","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.lfs.2024.122777_bb0195","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1177\/0960327119851260","article-title":"The protective effect of ligustrazine on rats with cerebral ischemia\u2013reperfusion injury via activating PI3K\/Akt pathway","volume":"38","author":"Ding","year":"2019","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.lfs.2024.122777_bb0200","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1097\/00004647-200112000-00009","article-title":"Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice","volume":"21","author":"Noshita","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.lfs.2024.122777_bb0205","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1097\/00004647-200104000-00004","article-title":"Activation of Akt\/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus","volume":"21","author":"Yano","year":"2001","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.lfs.2024.122777_bb0210","article-title":"Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions","volume":"7","author":"Qin","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.lfs.2024.122777_bb0215","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3164\/jcbn.14-134","article-title":"Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria","volume":"56","author":"Itoh","year":"2015","journal-title":"J. Clin. Biochem. Nutr."},{"key":"10.1016\/j.lfs.2024.122777_bb0220","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.freeradbiomed.2015.04.036","article-title":"The emerging role of Nrf2 in mitochondrial function","volume":"88","author":"Dinkova-Kostova","year":"2015","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.lfs.2024.122777_bb0225","doi-asserted-by":"crossref","first-page":"9210","DOI":"10.3892\/mmr.2017.7739","article-title":"Edaravone protects the retina against ischemia\/reperfusion-induced oxidative injury through the PI3K\/Akt\/Nrf2 pathway","volume":"16","author":"Xu","year":"2017","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.lfs.2024.122777_bb0230","article-title":"Pharmacological protection against ischemia-reperfusion injury by regulating the Nrf2-Keap1-ARE signaling pathway","volume":"10","author":"Ucar","year":"2021","journal-title":"Antioxidants (Basel, Switzerland)"},{"key":"10.1016\/j.lfs.2024.122777_bb0235","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.coph.2009.09.002","article-title":"The role of mitochondria in health and disease","volume":"9","author":"Johannsen","year":"2009","journal-title":"Curr. Opin. Pharmacol."},{"key":"10.1016\/j.lfs.2024.122777_bb0240","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0092-8674(00)80085-9","article-title":"Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c","volume":"86","author":"Liu","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.lfs.2024.122777_bb0245","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23169212","article-title":"The role of bioenergetics in neurodegeneration","volume":"23","author":"Strope","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0250","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1016\/j.drudis.2018.08.001","article-title":"Mitochondrial permeability transition pore: a potential drug target for neurodegeneration","volume":"23","author":"Kalani","year":"2018","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.lfs.2024.122777_bb0255","doi-asserted-by":"crossref","first-page":"13315","DOI":"10.1074\/jbc.R109.076596","article-title":"Use of venom peptides to probe ion channel structure and function","volume":"285","author":"Dutertre","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2024.122777_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.121365","article-title":"Animal toxins: as an alternative therapeutic target following ischemic stroke condition","volume":"317","author":"Neha","year":"2023","journal-title":"Life Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0265","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1111\/imb.12124","article-title":"Identification of a novel antimicrobial peptide, scolopendin 1, derived from centipede Scolopendra subspinipes mutilans and its antifungal mechanism","volume":"23","author":"Choi","year":"2014","journal-title":"Insect Mol. Biol."},{"key":"10.1016\/j.lfs.2024.122777_bb0270","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/cbdd.12702","article-title":"Rapid, and cost-effective protocol to deprotection of cysteine-rich conopeptide, omega-conotoxin MVIIA","volume":"87","author":"Eisapoor","year":"2016","journal-title":"Chem. Biol. Drug Des."},{"key":"10.1016\/j.lfs.2024.122777_bb0275","first-page":"3524","article-title":"Omega-conotoxin MVIIC attenuates neuronal apoptosis in vitro and improves significant recovery after spinal cord injury in vivo in rats","volume":"7","author":"Oliveira","year":"2014","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"10.1016\/j.lfs.2024.122777_bb0280","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1748-1716.1994.tb09713.x","article-title":"The omega-conopeptide SNX-111, an N-type calcium channel blocker, dramatically ameliorates brain damage due to transient focal ischaemia","volume":"150","author":"Zhao","year":"1994","journal-title":"Acta Physiol. Scand."},{"key":"10.1016\/j.lfs.2024.122777_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms21176197","article-title":"The role of amino acids in neurotransmission and fluorescent tools for their detection","volume":"21","author":"Dalangin","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0290","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s10571-010-9618-5","article-title":"The effect of spider toxin PhTx3-4, \u03c9-conotoxins MVIIA and MVIIC on glutamate uptake and on capsaicin-induced glutamate release and [Ca 2+]i in spinal cord synaptosomes","volume":"31","author":"Gon\u00e7aves","year":"2011","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.lfs.2024.122777_bb0295","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1007\/s12017-021-08692-w","article-title":"Spider neurotoxins as modulators of NMDA receptor signaling","volume":"24","author":"Pa\u0142asz","year":"2022","journal-title":"NeuroMolecular Med."},{"key":"10.1016\/j.lfs.2024.122777_bb0300","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.1073\/pnas.1614728114","article-title":"Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a","volume":"114","author":"Chassagnon","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.lfs.2024.122777_bb0305","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.apsb.2016.06.013","article-title":"The fate of medications evaluated for ischemic stroke pharmacotherapy over the period 1995\u20132015","volume":"6","author":"Chen","year":"2016","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.lfs.2024.122777_bb0310","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1124\/mol.105.017319","article-title":"Neurochemical characterization of a neuroprotective compound from Parawixia bistriata spider venom that inhibits synaptosomal uptake of GABA and glycine","volume":"69","author":"Beleboni","year":"2006","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.lfs.2024.122777_bb0315","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1021\/acschemneuro.0c00007","article-title":"Elucidation of the structure and synthesis of neuroprotective low molecular mass components of the Parawixia bistriata spider venom","volume":"11","author":"Forster","year":"2020","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.lfs.2024.122777_bb0320","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.neuropharm.2015.08.040","article-title":"PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a","volume":"99","author":"McCarthy","year":"2015","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.lfs.2024.122777_bb0325","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.toxicon.2007.07.020","article-title":"Effect of Huwentoxin-I on the Fas and TNF apoptosis pathway in the hippocampus of rat with global cerebral ischemia","volume":"50","author":"Wang","year":"2007","journal-title":"Toxicon"},{"key":"10.1016\/j.lfs.2024.122777_bb0330","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.toxicon.2003.10.009","article-title":"PnTx4-3, a new insect toxin from Phoneutria nigriventer venom elicits the glutamate uptake inhibition exhibited by PhTx4 toxic fraction","volume":"42","author":"Oliveira","year":"2003","journal-title":"Toxicon"},{"key":"10.1016\/j.lfs.2024.122777_bb0335","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1002\/hipo.20580","article-title":"Phoneutria spider toxins block ischemia-induced glutamate release, neuronal death, and loss of neurotransmission in hippocampus","volume":"19","author":"Pinheiro","year":"2009","journal-title":"Hippocampus"},{"key":"10.1016\/j.lfs.2024.122777_bb0340","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.1073\/pnas.1614728114","article-title":"Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a","volume":"114","author":"Chassagnon","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.lfs.2024.122777_bb0345","doi-asserted-by":"crossref","first-page":"936","DOI":"10.4049\/jimmunol.166.2.936","article-title":"Selective blocking of voltage-gated K+ channels improves experimental autoimmune encephalomyelitis and inhibits T cell activation","volume":"166","author":"Beeton","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.lfs.2024.122777_bb0350","article-title":"Scorpion venom heat-resistant peptide (SVHRP) enhances neurogenesis and neurite outgrowth of immature neurons in adult mice by up-regulating brain-derived neurotrophic factor (BDNF)","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2024.122777_bb0355","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.toxicon.2012.04.343","article-title":"Investigating the chemical profile of regenerated scorpion (Parabuthus transvaalicus) venom in relation to metabolic cost and toxicity","volume":"60","author":"Nisani","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.lfs.2024.122777_bb0360","doi-asserted-by":"crossref","first-page":"4853","DOI":"10.4049\/jimmunol.1500386","article-title":"Bee venom phospholipase A2, a novel Foxp3+ regulatory T cell inducer, protects dopaminergic neurons by modulating neuroinflammatory responses in a mouse model of Parkinson\u2019s disease","volume":"195","author":"Chung","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.lfs.2024.122777_bb0365","article-title":"Apitherapy for age-related skeletal muscle dysfunction (sarcopenia): a review on the effects of royal jelly, propolis, and bee pollen","volume":"9","author":"Ali","year":"2020","journal-title":"Foods (Basel, Switzerland)"},{"key":"10.1016\/j.lfs.2024.122777_bb0370","doi-asserted-by":"crossref","DOI":"10.3390\/toxins12030195","article-title":"Therapeutic effects of apamin as a bee venom component for non-neoplastic disease","volume":"12","author":"Gu","year":"2020","journal-title":"Toxins (Basel)."},{"key":"10.1016\/j.lfs.2024.122777_bb0375","doi-asserted-by":"crossref","unstructured":"C.G. Dantas, A.O. da Paix\u00e3o, T.L.G.M. Nunes, I.J.F. Silva, B. dos S. Lima, A.A.S. Ara\u00fajo, R.L.C. de Albuquerque-Junior, K.P. Gramacho, F.F. Padilha, L.P. da Costa, P. Severino, J.C. Cardoso, E.B. Souto, M.Z. Gomes, Africanized bee venom ( Apis mellifera Linnaeus): neuroprotective effects in a Parkinson's disease mouse model induced by 6-hydroxydopamine, Toxics 10 (2022). doi:https:\/\/doi.org\/10.3390\/TOXICS10100583.","DOI":"10.3390\/toxics10100583"},{"key":"10.1016\/j.lfs.2024.122777_bb0380","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/172502","article-title":"Knowledge, attitudes, and usage of apitherapy for disease prevention and treatment among undergraduate pharmacy students in Lithuania","volume":"2015","author":"Trumbeckaite","year":"2015","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.lfs.2024.122777_bb0385","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.3390\/toxins7041126","article-title":"Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan","volume":"7","author":"Moreno","year":"2015","journal-title":"Toxins (Basel)."},{"key":"10.1016\/j.lfs.2024.122777_bb0390","doi-asserted-by":"crossref","DOI":"10.3390\/toxins13090603","article-title":"Apamin enhances neurite outgrowth and regeneration after laceration injury in cortical neurons","volume":"13","author":"Kim","year":"2021","journal-title":"Toxins (Basel)"},{"key":"10.1016\/j.lfs.2024.122777_bb0395","article-title":"Neuroprotective activity of melittin-the main component of bee venom-against oxidative stress induced by A\u03b225-35 in in vitro and in vivo models","volume":"10","author":"Nguyen","year":"2021","journal-title":"Antioxidants (Basel, Switzerland)"},{"key":"10.1016\/j.lfs.2024.122777_bb0400","doi-asserted-by":"crossref","DOI":"10.3390\/molecules24162997","article-title":"Bee venom: overview of main compounds and bioactivities for therapeutic interests","volume":"24","author":"Wehbe","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.lfs.2024.122777_bb0405","doi-asserted-by":"crossref","DOI":"10.1186\/s40035-019-0167-7","article-title":"Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice","volume":"8","author":"Ham","year":"2019","journal-title":"Transl. Neurodegener."},{"key":"10.1016\/j.lfs.2024.122777_bb0410","doi-asserted-by":"crossref","DOI":"10.1038\/emm.2016.49","article-title":"Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson\u2019s disease alpha-synuclein transgenic mice","volume":"48","author":"Ye","year":"2016","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.lfs.2024.122777_bb0415","doi-asserted-by":"crossref","first-page":"6165","DOI":"10.1007\/s00253-016-7610-9","article-title":"Snake venom toxins: toxicity and medicinal applications","volume":"100","author":"Chan","year":"2016","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.lfs.2024.122777_bb0420","doi-asserted-by":"crossref","DOI":"10.3390\/toxins10010008","article-title":"Computational studies of snake venom toxins","volume":"10","author":"Ojeda","year":"2017","journal-title":"Toxins (Basel)."},{"key":"10.1016\/j.lfs.2024.122777_bb0425","doi-asserted-by":"crossref","first-page":"3030","DOI":"10.1007\/s00018-006-6315-0","article-title":"Snake venom components and their applications in biomedicine","volume":"63","author":"Koh","year":"2006","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0430","doi-asserted-by":"crossref","DOI":"10.3390\/ph15091153","article-title":"From snake venoms to therapeutics: a focus on natriuretic peptides","volume":"15","author":"Ang","year":"2022","journal-title":"Pharmaceuticals (Basel)"},{"key":"10.1016\/j.lfs.2024.122777_bb0435","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0197-0186(83)90028-1","article-title":"Fasciculin, a powerful anticholinesterase polypeptide from Dendroaspis angusticeps venom","volume":"5","author":"Rodr\u00edguez-Ithurralde","year":"1983","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.lfs.2024.122777_bb0440","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.toxicon.2016.11.001","article-title":"Serine proteinases from Bothrops snake venom activates PI3K\/Akt mediated angiogenesis","volume":"124","author":"Bhat","year":"2016","journal-title":"Toxicon"},{"key":"10.1016\/j.lfs.2024.122777_bb0445","doi-asserted-by":"crossref","DOI":"10.1186\/s40409-017-0132-9","article-title":"In silico analysis of binding interaction of conantokins with NMDA receptors for potential therapeutic use in Alzheimer\u2019s disease","volume":"23","author":"Waqar","year":"2017","journal-title":"J. Venom. Anim. Toxins Incl. Trop. Dis."},{"key":"10.1016\/j.lfs.2024.122777_bb0450","series-title":"Diversity in NMDA Receptor Composition","first-page":"62","volume":"19","author":"Sanz-Clemente","year":"2012"},{"key":"10.1016\/j.lfs.2024.122777_bb0455","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3390\/md403119","article-title":"Conotoxins: therapeutic potential and application","volume":"4","author":"Layer","year":"2006","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.lfs.2024.122777_bb0460","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1007\/s12017-021-08692-w","article-title":"Spider neurotoxins as modulators of NMDA receptor signaling","volume":"24","author":"Pa\u0142asz","year":"2022","journal-title":"NeuroMolecular Med."},{"key":"10.1016\/j.lfs.2024.122777_bb0465","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00253-008-1385-6","article-title":"Toxins from cone snails: properties, applications and biotechnological production","volume":"79","author":"Becker","year":"2008","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.lfs.2024.122777_bb0470","doi-asserted-by":"crossref","first-page":"344","DOI":"10.3390\/toxins14050344","article-title":"Biological effects of animal venoms on the human immune system","volume":"14","author":"Avalo","year":"2022","journal-title":"Toxins"},{"key":"10.1016\/j.lfs.2024.122777_bb0475","doi-asserted-by":"crossref","DOI":"10.3390\/ph15101168","article-title":"Molecular mechanisms of Inflammasome in ischemic stroke pathogenesis","volume":"15","author":"Puleo","year":"2022","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.lfs.2024.122777_bb0480","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s12291-019-00838-9","article-title":"Modes of calcium regulation in ischemic neuron","volume":"34","author":"Singh","year":"2019","journal-title":"Indian J. Clin. Biochem."},{"key":"10.1016\/j.lfs.2024.122777_bb0485","doi-asserted-by":"crossref","unstructured":"V. Monge-Fuentes, F.M.M. Gomes, G.A.A. Campos, J. de C. Silva, A.M. Biolchi, L.C. dos Anjos, J.C. Gon\u00e7alves, K.S. Lopes, M.R. Mortari, Neuroactive compounds obtained from arthropod venoms as new therapeutic platforms for the treatment of neurological disorders, J. Venom. Anim. Toxins Incl. Trop. Dis. 21 (2015). doi:https:\/\/doi.org\/10.1186\/S40409-015-0031-X.","DOI":"10.1186\/s40409-015-0031-x"},{"key":"10.1016\/j.lfs.2024.122777_bb0490","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s12291-019-00838-9","article-title":"Modes of calcium regulation in ischemic neuron","volume":"34","author":"Singh","year":"2019","journal-title":"Indian J. Clin. Biochem."},{"key":"10.1016\/j.lfs.2024.122777_bb0495","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.nbd.2011.04.018","article-title":"Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia\u2013ischemia in newborn piglet striatum","volume":"43","author":"Yang","year":"2011","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.lfs.2024.122777_bb0500","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/a0038550","article-title":"A brief history of the development of antidepressant drugs: from monoamines to glutamate","volume":"23","author":"Hillhouse","year":"2015","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.lfs.2024.122777_bb0505","first-page":"1","article-title":"Omega agatoxin IVB","author":"Terneus","year":"2007","journal-title":"XPharm Compr. Pharmacol. Ref."},{"key":"10.1016\/j.lfs.2024.122777_bb0510","author":"Schroeder"},{"key":"10.1016\/j.lfs.2024.122777_bb0515","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0204948","article-title":"Conotoxin MVIIA improves cell viability and antioxidant system after spinal cord injury in rats","volume":"13","author":"Oliveira","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2024.122777_bb0520","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0022-510X(97)00196-2","article-title":"SNX-111, a novel, presynaptic N-type calcium channel antagonist, is neuroprotective against focal cerebral ischemia in rabbits","volume":"153","author":"Perez-Pinzon","year":"1997","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0525","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0006-8993(01)02471-4","article-title":"Autoradiographic localization of N-type VGCCs in gerbil hippocampus and failure of omega-conotoxin MVIIA to attenuate neuronal injury after transient cerebral ischemia","volume":"907","author":"Azimi-Zonooz","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.lfs.2024.122777_bb0530","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0165093","article-title":"rLj-RGD3, a novel recombinant toxin protein from Lampetra japonica, protects against cerebral reperfusion injury following middle cerebral artery occlusion involving the integrin-PI3K\/Akt pathway in rats","volume":"11","author":"Lu","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2024.122777_bb0535","doi-asserted-by":"crossref","first-page":"76","DOI":"10.2174\/156652411794859232","article-title":"microRNAs in stroke pathogenesis","volume":"11","author":"Tan","year":"2011","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.lfs.2024.122777_bb0540","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12974-023-02739-4","article-title":"A short peptide exerts neuroprotective effects on cerebral ischemia\u2013reperfusion injury by reducing inflammation via the miR-6328\/IKK\u03b2\/NF-\u03baB axis","volume":"20","author":"Li","year":"2023","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.lfs.2024.122777_bb0545","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1038\/aps.2009.47","article-title":"Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors","volume":"30","author":"Azam","year":"2009","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.lfs.2024.122777_bb0550","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.biomaterials.2016.03.025","article-title":"MiRNA-124 induces neuroprotection and functional improvement after focal cerebral ischemia","volume":"91","author":"Hamzei Taj","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.lfs.2024.122777_bb0555","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1189\/jlb.0907654","article-title":"Crucial role of neutrophils in the development of mechanical inflammatory hypernociception","volume":"83","author":"Cunha","year":"2008","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.lfs.2024.122777_bb0560","doi-asserted-by":"crossref","first-page":"734","DOI":"10.4103\/1673-5374.353481","article-title":"MicroRNAs: protective regulators for neuron growth and development","volume":"18","author":"Ma","year":"2023","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.lfs.2024.122777_bb0565","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/s11064-023-04030-7","article-title":"Neuroprotective effects of melittin against cerebral ischemia and inflammatory injury via upregulation of MCPIP1 to suppress NF-\u03baB activation in vivo and in vitro","volume":"49","author":"Xing","year":"2024","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.lfs.2024.122777_bb0570","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1517\/14712598.2011.621940","article-title":"Venoms as a platform for human drugs: translating toxins into therapeutics","volume":"11","author":"King","year":"2011","journal-title":"Expert. Opin. Biol. Ther."},{"key":"10.1016\/j.lfs.2024.122777_bb0575","doi-asserted-by":"crossref","first-page":"12738","DOI":"10.1039\/C8CC06725B","article-title":"From venoms to BBB-shuttles. MiniCTX3: a molecular vector derived from scorpion venom","volume":"54","author":"D\u00edaz-Perlas","year":"2018","journal-title":"Chem. Commun."},{"key":"10.1016\/j.lfs.2024.122777_bb0580","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1002\/bip.22748","article-title":"Chlorotoxin: structure, activity, and potential uses in cancer therapy","volume":"106","author":"Ojeda","year":"2016","journal-title":"Pept. Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0585","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jconrel.2017.08.027","article-title":"A facile approach to functionalizing cell membrane-coated nanoparticles with neurotoxin-derived peptide for brain-targeted drug delivery","volume":"264","author":"Chai","year":"2017","journal-title":"J. Control. Release"},{"key":"10.1016\/j.lfs.2024.122777_bb0590","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00253-008-1385-6","article-title":"Toxins from cone snails: properties, applications and biotechnological production","volume":"79","author":"Becker","year":"2008","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.lfs.2024.122777_bb0595","doi-asserted-by":"crossref","first-page":"4130","DOI":"10.1074\/jbc.M109.054718","article-title":"Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels","volume":"285","author":"Redaelli","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2024.122777_bb0600","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.3390\/cancers15133388","article-title":"Diagnostic and therapeutic approaches for glioblastoma and neuroblastoma cancers using chlorotoxin nanoparticles","volume":"15","author":"Robles-Escajeda","year":"2023","journal-title":"Cancers"},{"key":"10.1016\/j.lfs.2024.122777_bb0605","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23031851","article-title":"A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of Nanotherapeutics","volume":"23","author":"Lamptey","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2024.122777_bb0610","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/antiox9101022","article-title":"Merging the multi-target effects of phytochemicals in neurodegeneration: from oxidative stress to protein aggregation and inflammation","volume":"9","author":"Limanaqi","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.lfs.2024.122777_bb0615","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4331\/wjbc.v8.i1.4","article-title":"Modern trends in animal venom research - omics and nanomaterials","volume":"8","author":"Utkin","year":"2017","journal-title":"World J. Biol. Chem."},{"key":"10.1016\/j.lfs.2024.122777_bb0620","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1124\/pr.113.008367","article-title":"Novel delivery systems for improving the clinical use of peptides","volume":"67","author":"Kovalainen","year":"2015","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.lfs.2024.122777_bb0625","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.irn.2017.08.006","article-title":"Current strategies for the delivery of therapeutic proteins and enzymes to treat brain disorders","volume":"137","author":"Duskey","year":"2017","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.lfs.2024.122777_bb0630","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.colsurfb.2017.12.013","article-title":"Design and characterization of crotamine-functionalized gold nanoparticles","volume":"163","author":"Karpel","year":"2018","journal-title":"Colloids Surf. B: Biointerfaces"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320524003679?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320524003679?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T10:58:32Z","timestamp":1725879512000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320524003679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":126,"alternative-id":["S0024320524003679"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2024.122777","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Toxin-derived peptides: An unconventional approach to alleviating cerebral stroke burden and neurobehavioral impairments","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2024.122777","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"122777"}}