{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T23:25:27Z","timestamp":1771889127344,"version":"3.50.1"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.lfs.2024.123233","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T21:40:50Z","timestamp":1731102050000},"page":"123233","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Tempol mitigates inflammation, oxidative stress, and histopathological alterations of cadmium-induced parotid gland injury in rats"],"prefix":"10.1016","volume":"359","author":[{"given":"Samaa Salah Abd","family":"El-Fatah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ola Elsayed","family":"Nafea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doaa Mohammed","family":"Yousef","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walaa","family":"Samy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marwa H.S.","family":"Hussien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heba M.","family":"Arakeep","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2024.123233_bb0005","article-title":"Protective effect of quercetin on cadmium-induced kidney apoptosis in rats based on PERK signaling pathway","volume":"82","author":"Ding","year":"2024","journal-title":"J. Trace Elem. Med. Biol. Organ Soc. Miner. Trace Elem."},{"key":"10.1016\/j.lfs.2024.123233_bb0010","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1289\/ehp.1002077","article-title":"Blood and urine cadmium, blood pressure, and hypertension: a systematic review and meta-analysis","volume":"118","author":"Gallagher","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.lfs.2024.123233_bb0015","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1007\/s00198-020-05429-6","article-title":"Exposure to heavy metals and the risk of osteopenia or osteoporosis: a systematic review and meta-analysis","volume":"31","author":"Jalili","year":"2020","journal-title":"Osteoporos. Int."},{"key":"10.1016\/j.lfs.2024.123233_bb0020","doi-asserted-by":"crossref","first-page":"485","DOI":"10.3390\/ijerph20010485","article-title":"Association between environmental cadmium exposure and osteoporosis risk in postmenopausal women: a systematic review and meta-analysis","volume":"20","author":"Kunioka","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.lfs.2024.123233_bb0025","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1265\/ehpm.24-00063","article-title":"A suspected case of \u201citai-itai disease\u201d in a cadmium-polluted area in Akita prefecture, Japan","volume":"29","author":"Sasaki","year":"2024","journal-title":"Environ. Health Prev. Med."},{"key":"10.1016\/j.lfs.2024.123233_bb0030","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1016\/j.forsciint.2012.01.032","article-title":"An investigation and pathological analysis of two fatal cases of cadmium poisoning","volume":"220","author":"Chang","year":"2012","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.lfs.2024.123233_bb0035","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1289\/ehp.021101261","article-title":"Cadmium exposure and nephropathy in a 28-year-old female metals worker","volume":"110","author":"Wittman","year":"2002","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.lfs.2024.123233_bb0040","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s11655-020-3089-4","article-title":"Treatment of an acute severe cadmium poisoning patient combined with multiple organ dysfunction syndromes by integrated Chinese and Western medicines: a case report","volume":"26","author":"Zhou","year":"2020","journal-title":"Chin. J. Integr. Med."},{"key":"10.1016\/j.lfs.2024.123233_bb0045","article-title":"Factors moderating cadmium bioavailability: key considerations for comparing blood cadmium levels between groups","volume":"191","author":"Cirovic","year":"2024","journal-title":"Food Chem. Toxicol. An Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"key":"10.1016\/j.lfs.2024.123233_bb0050","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1265\/jjh.72.149","article-title":"Itai-itai disease: lessons from the investigations of environmental epidemiology conducted in the 1970\u2019s, with special reference to the studies of the Toyama Institute of Health, Nippon Eiseigaku Zasshi","volume":"72","author":"Aoshima","year":"2017","journal-title":"Japanese J. Hyg."},{"key":"10.1016\/j.lfs.2024.123233_bb0055","series-title":"Application of Zinc Oxide Nanoparticles to Mitigate Cadmium Toxicity: Mechanisms and Future Prospects., Plants (Basel, Switzerland)","volume":"vol. 13","author":"Umair Hassan","year":"2024"},{"key":"10.1016\/j.lfs.2024.123233_bb0065","doi-asserted-by":"crossref","DOI":"10.1038\/emm.2017.125","article-title":"Cadmium-induced ER stress and inflammation are mediated through C\/EBP\u2013DDIT3 signaling in human bronchial epithelial cells","volume":"49","author":"Kim","year":"2017","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.lfs.2024.123233_bb0070","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1515\/reveh-2016-0042","article-title":"Environmental and occupational exposure to cadmium in Iran: a systematic review","volume":"31","author":"Tavakkoli","year":"2016","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.lfs.2024.123233_bb0075","first-page":"553","article-title":"Investigating the relationship between cadmium exposure and the risk of prostate cancer: a systematic review and dose-response meta-analysis","volume":"53","author":"Mohammadian-Hafshejani","year":"2024","journal-title":"Iran. J. Public Health"},{"key":"10.1016\/j.lfs.2024.123233_bb0080","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.3390\/agronomy12081952","article-title":"Cadmium accumulation in cereal crops and tobacco: a review","volume":"12","author":"Mei","year":"2022","journal-title":"Agronomy"},{"key":"10.1016\/j.lfs.2024.123233_bb0085","doi-asserted-by":"crossref","DOI":"10.3390\/toxics12060388","article-title":"Cadmium exposure: mechanisms and pathways of toxicity and implications for human health","volume":"12","author":"Qu","year":"2024","journal-title":"Toxics"},{"key":"10.1016\/j.lfs.2024.123233_bb0090","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jnutbio.2016.03.001","article-title":"Grape seed proanthocyanidins protects against cadmium-induced oxidative pancreatitis in rats by attenuating oxidative stress, inflammation, and apoptosis via Nrf-2\/HO-1 signaling","volume":"32","author":"Bashir","year":"2016","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.lfs.2024.123233_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2022.116313","article-title":"Agomelatine ameliorates cadmium-induced toxicity through the modification of HMGB-1\/TLR-4\/NF\u03baB pathway","volume":"457","author":"Hafez","year":"2022","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.lfs.2024.123233_bb0100","doi-asserted-by":"crossref","first-page":"97","DOI":"10.12703\/P6-97","article-title":"MyD88: a central player in innate immune signaling","volume":"6","author":"Deguine","year":"2014","journal-title":"F1000Prime Rep."},{"key":"10.1016\/j.lfs.2024.123233_bb0105","first-page":"245","article-title":"Ultrastructural study of the submandibular gland of the rat after 6-month exposure to cadmium and zinc in drinking water","volume":"51","author":"Dabrowska","year":"2006","journal-title":"Adv. Med. Sci."},{"key":"10.1016\/j.lfs.2024.123233_bb0110","doi-asserted-by":"crossref","first-page":"831","DOI":"10.18388\/abp.2004_3566","article-title":"Activity of lysosomal exoglycosidases in submandibular glands of rats intoxicated by cadmium at doses related to human chronic environmental and occupational exposures","volume":"51","author":"Zalewska","year":"2004","journal-title":"Acta Biochim. Pol."},{"issue":"Suppl. 1","key":"10.1016\/j.lfs.2024.123233_bb0115","first-page":"175","article-title":"A preliminary study of the submandibular gland of the rat after one-year cadmium intoxication. Part II. Pathomorphology and ultrastructure","volume":"49","author":"Czykier","year":"2004","journal-title":"Rocz. Akad. Med. Bialymst."},{"key":"10.1016\/j.lfs.2024.123233_bb0120","doi-asserted-by":"crossref","first-page":"3403264","DOI":"10.1155\/2019\/3403264","article-title":"The protective impact of black chokeberry fruit extract (Aronia melanocarpa L.) on the oxidoreductive system of the parotid gland of rats exposed to cadmium","volume":"2019","author":"D\u0105browska","year":"2019","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.lfs.2024.123233_bb0125","series-title":"Contemp. Oral Med","first-page":"1437","article-title":"Salivary gland disorders and diseases","author":"Jensen","year":"2019"},{"key":"10.1016\/j.lfs.2024.123233_bb0130","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.3390\/antiox10111666","article-title":"Mechanism, prevention, and treatment of radiation-induced salivary gland injury related to oxidative stress","volume":"10","author":"Liu","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.lfs.2024.123233_bb0135","first-page":"124","article-title":"Saliva--A diagnostic window to the body, both in health and in disease","volume":"2","author":"Greabu","year":"2009","journal-title":"J. Med. Life"},{"key":"10.1016\/j.lfs.2024.123233_bb0140","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12929-022-00819-w","article-title":"Bioengineering in salivary gland regeneration","volume":"29","author":"Hajiabbas","year":"2022","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.lfs.2024.123233_bb0145","doi-asserted-by":"crossref","first-page":"4095","DOI":"10.3390\/jcm9124095","article-title":"Radiation-induced salivary gland dysfunction: mechanisms, therapeutics, and future directions","volume":"9","author":"Jasmer","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.lfs.2024.123233_bb0150","article-title":"Atrophy and inflammatory changes in salivary glands induced by oxidative stress after exposure to drugs and other chemical substances: a systematic review","volume":"59","author":"Ungureanu","year":"2023","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.lfs.2024.123233_bb0155","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.ajem.2024.06.009","article-title":"Evaluation of effects of Tempol on testicular ischemia\/reperfusion injury","volume":"82","author":"Ganjiani","year":"2024","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.lfs.2024.123233_bb0160","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s11033-023-09039-3","article-title":"4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (Tempol) alleviates lung injury by inhibiting SIRT6-HIF-1\u03b1 signaling pathway activation through the upregulation of miR-212-5p expression","volume":"51","author":"Ai","year":"2024","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.lfs.2024.123233_bb0165","doi-asserted-by":"crossref","first-page":"859","DOI":"10.2174\/1573406419666230505150020","article-title":"Mechanistic role of tempol: synthesis, catalysed reactions and therapeutic potential","volume":"19","author":"Tiwari","year":"2023","journal-title":"Med. Chem."},{"key":"10.1016\/j.lfs.2024.123233_bb0170","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.pharmthera.2010.01.003","article-title":"Effects of tempol and redox-cycling nitroxides in models of oxidative stress","volume":"126","author":"Wilcox","year":"2010","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.lfs.2024.123233_bb0175","doi-asserted-by":"crossref","first-page":"H97","DOI":"10.1152\/ajpheart.00786.2018","article-title":"Apocynin and tempol ameliorate dietary sodium-induced declines in cutaneous microvascular function in salt-resistant humans","volume":"317","author":"Ramick","year":"2019","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.lfs.2024.123233_bb0180","doi-asserted-by":"crossref","DOI":"10.1111\/and.13514","article-title":"The efficacy of antioxidants in sperm parameters and production of reactive oxygen species levels during the freeze-thaw process: a systematic review and meta-analysis","volume":"52","author":"Bahmyari","year":"2020","journal-title":"Andrologia"},{"key":"10.1016\/j.lfs.2024.123233_bb0185","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1096\/fba.1021","article-title":"TRPC1 expression and function inhibit ER stress and cell death in salivary gland cells","volume":"1","author":"Sukumaran","year":"2019","journal-title":"FASEB BioAdvances"},{"key":"10.1016\/j.lfs.2024.123233_bb0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1515\/hsz-2013-0174","article-title":"Stressed to death \u2013 mechanisms of ER stress-induced cell death","volume":"395","author":"Sovolyova","year":"2014","journal-title":"Biol. Chem."},{"key":"10.1016\/j.lfs.2024.123233_bb0195","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/978-981-15-0602-4_8","article-title":"Endoplasmic reticulum stress and autophagy","volume":"1206","author":"Qi","year":"2019","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.lfs.2024.123233_bb0200","doi-asserted-by":"crossref","first-page":"7564","DOI":"10.1158\/1078-0432.CCR-05-0958","article-title":"Kinetics of tempol for prevention of xerostomia following head and neck irradiation in a mouse model","volume":"11","author":"Cotrim","year":"2005","journal-title":"Clin. Cancer Res. An Off. J. Am. Assoc. Cancer Res."},{"key":"10.1016\/j.lfs.2024.123233_bb0205","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1080\/13813455.2019.1687523","article-title":"DoseCal: a virtual calculator for dosage conversion between human and different animal species","volume":"128","author":"Janhavi","year":"2022","journal-title":"Arch. Physiol. Biochem."},{"key":"10.1016\/j.lfs.2024.123233_bb0210","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/0003-9969(89)90059-9","article-title":"Effects of cadmium on the function and structure of the rat salivary glands","volume":"34","author":"Chiarenza","year":"1989","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.lfs.2024.123233_bb0215","series-title":"Bancroft\u2019s Theory Pract. Histol. Tech","first-page":"126","article-title":"The hematoxylin and eosin","author":"Bancroft","year":"2019"},{"key":"10.1016\/j.lfs.2024.123233_bb0220","series-title":"Bancroft's Theory Pract. Histol. Tech","first-page":"434","article-title":"Transmission electron microscopy","author":"Woods","year":"2019"},{"key":"10.1016\/j.lfs.2024.123233_bb0225","doi-asserted-by":"crossref","first-page":"101886","DOI":"10.1016\/j.redox.2021.101886","article-title":"Tempol ameliorates polycystic ovary syndrome through attenuating intestinal oxidative stress and modulating of gut microbiota composition-serum metabolites interaction","volume":"41","author":"Li","year":"2021","journal-title":"Redox Biol."},{"key":"10.1016\/j.lfs.2024.123233_bb0230","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12964-021-00811-1","article-title":"Mechanism of MyD88S mediated signal termination","volume":"20","author":"Pustelny","year":"2022","journal-title":"Cell Commun. Signal"},{"key":"10.1016\/j.lfs.2024.123233_bb0235","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.yjmcc.2021.08.001","article-title":"MyD88: at the heart of inflammatory signaling and cardiovascular disease","volume":"161","author":"Bayer","year":"2021","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.lfs.2024.123233_bb0240","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.00807","article-title":"Insight into TLR4-mediated immunomodulation in normal pregnancy and related disorders","volume":"11","author":"Firmal","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.lfs.2024.123233_bb0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.120971","article-title":"The role of inflammation in cadmium nephrotoxicity: NF-\u03baB comes into view","volume":"308","author":"Hassanein","year":"2022","journal-title":"Life Sci."},{"key":"10.1016\/j.lfs.2024.123233_bb0250","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/toxsci\/kfn087","article-title":"Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte cocultures","volume":"104","author":"Yu","year":"2008","journal-title":"Toxicol. Sci. An Off. J. Soc. Toxicol."},{"key":"10.1016\/j.lfs.2024.123233_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2023.119469","article-title":"Open questions in the NF-\u03baB field","volume":"1871","author":"Bacher","year":"2024","journal-title":"Biochim. Biophys. Acta. Mol. Cell Res."},{"key":"10.1016\/j.lfs.2024.123233_bb0260","series-title":"Efficacy of the Radical Scavenger, Tempol, to Reduce Inflammation and Oxidative Stress in a Murine Model of Atopic Dermatitis., Antioxidants (Basel, Switzerland)","volume":"vol. 12","author":"Ardizzone","year":"2023"},{"key":"10.1016\/j.lfs.2024.123233_bb0265","doi-asserted-by":"crossref","first-page":"4928","DOI":"10.1158\/1078-0432.CCR-07-0662","article-title":"Differential radiation protection of salivary glands versus tumor by Tempol with accompanying tissue assessment of Tempol by magnetic resonance imaging","volume":"13","author":"Cotrim","year":"2007","journal-title":"Clin. Cancer Res. An Off. J. Am. Assoc. Cancer Res."},{"key":"10.1016\/j.lfs.2024.123233_bb0270","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1158\/1078-0432.CCR-03-0194","article-title":"The stable nitroxide tempol facilitates salivary gland protection during head and neck irradiation in a mouse model","volume":"10","author":"Vitolo","year":"2004","journal-title":"Clin. Cancer Res. An Off. J. Am. Assoc. Cancer Res."},{"key":"10.1016\/j.lfs.2024.123233_bb0275","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s12882-024-03495-0","article-title":"Assessing the effects of tempol on renal fibrosis, inflammation, and oxidative stress in a high-salt diet combined with 5\/6 nephrectomy rat model: utilizing oxidized albumin as a biomarker","volume":"25","author":"Liu","year":"2024","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.lfs.2024.123233_bb0280","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1007\/s11010-022-04620-z","article-title":"Tempol and silymarin rescue from zinc-induced degeneration of dopaminergic neurons through modulation of oxidative stress and inflammation","volume":"478","author":"Singh","year":"2023","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.lfs.2024.123233_bb0285","doi-asserted-by":"crossref","DOI":"10.3390\/biom11030352","article-title":"Beneficial effect of tempol, a membrane-permeable radical scavenger, on inflammation and osteoarthritis in in vitro models","volume":"11","author":"Calabrese","year":"2021","journal-title":"Biomolecules"},{"key":"10.1016\/j.lfs.2024.123233_bb0290","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1089\/jop.2019.0016","article-title":"Effect of tempol, a membrane-permeable free radical scavenger, on in vitro model of eye inflammation on rabbit corneal cells","volume":"35","author":"Crupi","year":"2019","journal-title":"J. Ocul. Pharmacol. Ther."},{"key":"10.1016\/j.lfs.2024.123233_bb0295","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.atherosclerosis.2015.03.012","article-title":"The nitroxide radical tempol prevents obesity, hyperlipidemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE\u2212\/\u2212 mice","volume":"240","author":"Kim","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.lfs.2024.123233_bb0300","first-page":"1238","article-title":"Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress","volume":"21","author":"Wang","year":"2018","journal-title":"Iran. J. Basic Med. Sci."},{"key":"10.1016\/j.lfs.2024.123233_bb0305","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1177\/0960327119836203","article-title":"Anti-inflammatory role of tempol (4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl) in nephroprotection","volume":"38","author":"Afjal","year":"2019","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.lfs.2024.123233_bb0310","doi-asserted-by":"crossref","first-page":"445","DOI":"10.33549\/physiolres.934010","article-title":"Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis","volume":"68","author":"Wang","year":"2019","journal-title":"Physiol. Res."},{"key":"10.1016\/j.lfs.2024.123233_bb0315","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/pros.24473","article-title":"Tempol differential effect on prostate cancer inflammation: in vitro and in vivo evaluation","volume":"83","author":"Rossetto","year":"2023","journal-title":"Prostate"},{"key":"10.1016\/j.lfs.2024.123233_bb0320","doi-asserted-by":"crossref","first-page":"11634","DOI":"10.3390\/ijms231911634","article-title":"Physiological cooperation between aquaporin 5 and TRPV4","volume":"23","author":"Kem\u00e9ny","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2024.123233_bb0325","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0021-5198(19)30602-X","article-title":"Aquaporin water channel in salivary glands","volume":"83","author":"Ishikawa","year":"2000","journal-title":"Jpn. J. Pharmacol."},{"key":"10.1016\/j.lfs.2024.123233_bb0330","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1080\/01480545.2020.1831011","article-title":"Tempol (4-hydroxy tempo) protects mice from cisplatin-induced acute kidney injury via modulation of expression of aquaporins and kidney injury molecule-1","volume":"45","author":"Afjal","year":"2022","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.lfs.2024.123233_bb0335","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1172\/JCI61332","article-title":"Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT\/mTOR signaling","volume":"122","author":"Selvaraj","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.lfs.2024.123233_bb0340","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.3390\/ijms21051739","article-title":"Transient receptor potential canonical (TRPC) channels as modulators of migration and invasion","volume":"21","author":"Asghar","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2024.123233_bb0345","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.643972","article-title":"Toxic mechanisms of five heavy metals: mercury, lead, chromium, cadmium, and arsenic","volume":"12","author":"Balali-Mood","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.lfs.2024.123233_bb0350","doi-asserted-by":"crossref","first-page":"653","DOI":"10.21608\/edj.2016.95081","article-title":"Cadmium-induced apoptosis and cellular toxicity in rats major salivary glands","volume":"62","author":"Amin","year":"2016","journal-title":"Egypt. Dent. J."},{"key":"10.1016\/j.lfs.2024.123233_bb0355","doi-asserted-by":"crossref","first-page":"480","DOI":"10.4103\/0973-029X.190952","article-title":"Pathophysiology of myoepithelial cells in salivary glands","volume":"20","author":"Shah","year":"2016","journal-title":"J. Oral Maxillofac. Pathol."},{"key":"10.1016\/j.lfs.2024.123233_bb0360","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jtos.2023.12.003","article-title":"A closer look into the cellular and molecular biology of myoepithelial cells across various exocrine glands","volume":"31","author":"Mauduit","year":"2024","journal-title":"Ocul. Surf."},{"key":"10.1016\/j.lfs.2024.123233_bb0365","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s40610-015-0020-4","article-title":"Myoepithelial cells: their origin and function in lacrimal gland morphogenesis, homeostasis, and repair","volume":"1","author":"Makarenkova","year":"2015","journal-title":"Curr. Mol. Biol. Reports."},{"key":"10.1016\/j.lfs.2024.123233_bb0370","series-title":"Found. Diagnostic Pathol. Ser","first-page":"275","article-title":"Chapter 25 - overview of immunohistochemistry in breast lesions","author":"Mohsin","year":"2006"},{"key":"10.1016\/j.lfs.2024.123233_bb0375","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s11010-007-9629-9","article-title":"Effects of decorin on the expression of alpha-smooth muscle actin in a human myofibroblast cell line","volume":"308","author":"Nakatani","year":"2008","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.lfs.2024.123233_bb0380","doi-asserted-by":"crossref","first-page":"479","DOI":"10.4103\/IJPM.IJPM_482_17","article-title":"Expression of \u03b1-smooth muscle actin in benign and malignant salivary gland tumors: an immunohistochemical study","volume":"61","author":"Ravi","year":"2018","journal-title":"Indian J. Pathol. Microbiol."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320524008233?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320524008233?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T12:06:08Z","timestamp":1738152368000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320524008233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":75,"alternative-id":["S0024320524008233"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2024.123233","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tempol mitigates inflammation, oxidative stress, and histopathological alterations of cadmium-induced parotid gland injury in rats","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2024.123233","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"123233"}}