{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T21:16:04Z","timestamp":1772572564396,"version":"3.50.1"},"reference-count":132,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.lfs.2025.123478","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T07:56:01Z","timestamp":1739951761000},"page":"123478","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["The methyl-CpG-binding protein 2 (Mecp2) regulates the hypothalamic mitochondrial function and white adipose tissue lipid metabolism"],"prefix":"10.1016","volume":"366-367","author":[{"given":"Nuria","family":"Llontop","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristian","family":"Mancilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Ojeda-Provoste","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angie K.","family":"Torres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Godoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheril","family":"Tapia-Rojas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bredford","family":"Kerr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2025.123478_bb0005","series-title":"Obesity and Overweight","author":"World Health Organization, WHO","year":"2021"},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0010","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1007\/s13679-020-00422-w","article-title":"Long-term efficacy and safety of anti-obesity treatment: where do we stand?","volume":"10","author":"Tak","year":"2021","journal-title":"Curr. Obes. Rep."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0015","doi-asserted-by":"crossref","first-page":"11","DOI":"10.2147\/ciia.2006.1.1.11","article-title":"Dietary approaches that delay age-related diseases","volume":"1","author":"Everitt","year":"2006","journal-title":"Clin. Interv. Aging"},{"key":"10.1016\/j.lfs.2025.123478_bb0020","series-title":"Obesity Update","author":"OECD","year":"2017"},{"issue":"4","key":"10.1016\/j.lfs.2025.123478_bb0025","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s11154-013-9261-9","article-title":"Brain regulation of energy balance and body weight","volume":"14","author":"Rui","year":"2013","journal-title":"Rev. Endocr. Metab. Disord."},{"key":"10.1016\/j.lfs.2025.123478_bb0030","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.redox.2017.04.019","article-title":"Traveling from the hypothalamus to the adipose tissue: the thermogenic pathway","volume":"12","author":"Contreras","year":"2017","journal-title":"Redox Biol."},{"key":"10.1016\/j.lfs.2025.123478_bb0035","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.898139","article-title":"Hypothalamic estrogen signaling and adipose tissue metabolism in energy homeostasis","volume":"13","author":"Torres Irizarry","year":"2022","journal-title":"Front. Endocrinol."},{"issue":"10","key":"10.1016\/j.lfs.2025.123478_bb0040","doi-asserted-by":"crossref","first-page":"3131","DOI":"10.1002\/fsn3.1169","article-title":"Diet-induced DNA methylation within the hypothalamic arcuate nucleus and dysregulated leptin and insulin signaling in the pathophysiology of obesity","volume":"7","author":"Samodien","year":"2019","journal-title":"Food Sci. Nutr."},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0045","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/s42255-021-00345-3","article-title":"POMC neuronal heterogeneity in energy balance and beyond: an integrated view","volume":"3","author":"Quarta","year":"2021","journal-title":"Nat. Metab."},{"issue":"4","key":"10.1016\/j.lfs.2025.123478_bb0050","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.neuron.2017.06.014","article-title":"Toward a wiring diagram understanding of appetite control","volume":"95","author":"Andermann","year":"2017","journal-title":"Neuron"},{"issue":"4","key":"10.1016\/j.lfs.2025.123478_bb0055","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/s12276-022-00741-z","article-title":"Hypothalamic control of energy expenditure and thermogenesis","volume":"54","author":"Tran","year":"2022","journal-title":"Exp. Mol. Med."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0060","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1152\/ajpgi.00554.2006","article-title":"Regulation of triglyceride metabolism. IV. Hormonal regulation of lipolysis in adipose tissue","volume":"293","author":"Jaworski","year":"2007","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"8","key":"10.1016\/j.lfs.2025.123478_bb0065","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.arcmed.2008.09.005","article-title":"White adipose tissue as endocrine organ and its role in obesity","volume":"39","author":"V\u00e1zquez-Vela","year":"2008","journal-title":"Arch. Med. Res."},{"issue":"12","key":"10.1016\/j.lfs.2025.123478_bb0070","doi-asserted-by":"crossref","first-page":"2584","DOI":"10.3390\/cells9122584","article-title":"The Beta3 adrenergic receptor in healthy and pathological cardiovascular tissues","volume":"9","author":"Michel","year":"2020","journal-title":"Cells"},{"issue":"1\u20132","key":"10.1016\/j.lfs.2025.123478_bb0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2004.04.041","article-title":"Increased ATP content\/production in the hypothalamus may be a signal for energy-sensing of satiety: studies of the anorectic mechanism of a plant steroidal glycoside","volume":"1020","author":"MacLean","year":"2004","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0080","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1080\/15592294.2018.1451720","article-title":"Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches","volume":"13","author":"Vogel Ciernia","year":"2018","journal-title":"Epigenetics"},{"issue":"17","key":"10.1016\/j.lfs.2025.123478_bb0085","doi-asserted-by":"crossref","first-page":"5964","DOI":"10.3390\/ijms21175964","article-title":"Interplay between peripheral and central inflammation in obesity-promoted disorders: the impact on synaptic mitochondrial functions","volume":"21","author":"Crispino","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2025.123478_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101674","article-title":"Mitochondrial electron transport chain: oxidative phosphorylation, oxidant production, and methods of measurement","volume":"37","author":"Nolfi-Donegan","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.lfs.2025.123478_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101558","article-title":"Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss","volume":"34","author":"Olesen","year":"2020","journal-title":"Redox Biol."},{"issue":"4","key":"10.1016\/j.lfs.2025.123478_bb0100","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1152\/physrev.00001.2015","article-title":"The mitochondrial permeability transition pore: channel formation by F-ATP synthase, integration in signal transduction, and role in pathophysiology","volume":"95","author":"Bernardi","year":"2015","journal-title":"Physiol. Rev."},{"issue":"12","key":"10.1016\/j.lfs.2025.123478_bb0105","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1016\/j.drudis.2018.08.001","article-title":"Mitochondrial permeability transition pore: a potential drug target for neurodegeneration","volume":"23","author":"Kalani","year":"2018","journal-title":"Drug Discov. Today"},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0110","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1128\/MCB.05603-11","article-title":"Mitochondrial fission contributes to mitochondrial dysfunction and insulin resistance in skeletal muscle","volume":"32","author":"Jheng","year":"2012","journal-title":"Mol. Cell. Biol."},{"issue":"8","key":"10.1016\/j.lfs.2025.123478_bb0115","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1161\/CIRCRESAHA.111.246140","article-title":"Mitochondria and cardiovascular aging","volume":"110","author":"Dai","year":"2012","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0120","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1752-8062.2011.00357.x","article-title":"Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa","volume":"5","author":"Taub","year":"2012","journal-title":"Clin. Transl. Sci."},{"issue":"16","key":"10.1016\/j.lfs.2025.123478_bb0125","doi-asserted-by":"crossref","first-page":"6033","DOI":"10.1073\/pnas.0401626101","article-title":"Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice","volume":"101","author":"Luikenhuis","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0130","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1139\/O08-115","article-title":"Recent advances in MeCP2 structure and function","volume":"87","author":"Hite","year":"2009","journal-title":"Biochemistry and Cell Biology"},{"key":"10.1016\/j.lfs.2025.123478_bb0135","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.conb.2019.04.004","article-title":"MeCP2: an epigenetic regulator of critical periods","volume":"59","author":"Picard","year":"2019","journal-title":"Curr. Opin. Neurobiol."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0140","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/ajmg.10005","article-title":"Preserved speech variants of the Rett syndrome: molecular and clinical analysis","volume":"104","author":"Zappella","year":"2001","journal-title":"Am. J. Med. Genet."},{"issue":"12","key":"10.1016\/j.lfs.2025.123478_bb0145","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1093\/hmg\/ddn061","article-title":"Defective body-weight regulation, motor control and abnormal social interactions in Mecp2 hypomorphic mice","volume":"17","author":"Kerr","year":"2008","journal-title":"Hum. Mol. Genet."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0150","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/ejhg.2011.145","article-title":"Transgenic complementation of MeCP2 deficiency: phenotypic rescue of Mecp2-null mice by isoform-specific transgenes","volume":"20","author":"Kerr","year":"2012","journal-title":"European Journal of Human Genetics"},{"key":"10.1016\/j.lfs.2025.123478_bb0155","doi-asserted-by":"crossref","first-page":"479","DOI":"10.3389\/fphys.2019.00479","article-title":"Neuronal redox-imbalance in Rett syndrome affects mitochondria as well as cytosol, and is accompanied by intensified mitochondrial O2 consumption and ROS release","volume":"10","author":"Can","year":"2019","journal-title":"Front. Physiol."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0160","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.nbd.2012.06.007","article-title":"Oxidative burden and mitochondrial dysfunction in a mouse model of Rett syndrome","volume":"48","author":"Gro\u00dfer","year":"2012","journal-title":"Neurobiol. Dis."},{"issue":"6","key":"10.1016\/j.lfs.2025.123478_bb0165","article-title":"Metformin exposure during pregnancy and lactation affects offspring\u2019s long-term body weight and adipose tissue mass independent of the maternal metabolic state","volume":"1870","author":"Francisca","year":"2024","journal-title":"Biochimica et Biophysica Acta"},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0170","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12868-018-0403-6","article-title":"Evaluation of reference genes for gene expression studies in mouse and N2a cell ischemic stroke models using quantitative real-time PCR","volume":"19","author":"Kang","year":"2018","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.lfs.2025.123478_bb0175","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.3398","article-title":"Selection of housekeeping genes as internal controls for quantitative RT-PCR analysis of the veined rapa whelk (Rapana venosa)","volume":"5","author":"Song","year":"2017","journal-title":"PeerJ"},{"issue":"9","key":"10.1016\/j.lfs.2025.123478_bb0180","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1113\/expphysiol.2014.079798","article-title":"The increase in body weight induced by lack of methyl CpG binding protein-2 is associated with altered leptin signalling in the hypothalamus","volume":"99","author":"Torres-Andrade","year":"2014","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.lfs.2025.123478_bb0185","doi-asserted-by":"crossref","first-page":"188","DOI":"10.3389\/fnmol.2017.00188","article-title":"Mecp2 mediates experience-dependent transcriptional upregulation of ryanodine receptor Type-3","volume":"10","author":"Torres","year":"2017","journal-title":"Front. Mol. Neurosci."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0190","doi-asserted-by":"crossref","first-page":"4448","DOI":"10.1038\/s41598-021-83910-w","article-title":"Pathologically phosphorylated tau at S396\/404 (PHF-1) is accumulated inside of hippocampal synaptic mitochondria of aged wild-type mice","volume":"11","author":"Torres","year":"2021","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.lfs.2025.123478_bb0195","doi-asserted-by":"crossref","first-page":"5476","DOI":"10.3390\/ijms24065476","article-title":"Mitochondrial bioenergetics, redox balance, and calcium homeostasis dysfunction with defective ultrastructure and quality control in the Hippocampus of aged female C57BL\/6J mice","volume":"24","author":"Torres","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0200","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/1096-9861(20001016)426:2<297::AID-CNE10>3.0.CO;2-O","article-title":"Mitochondrial free calcium levels (Rhod-2 fluorescence) and ultrastructural alterations in neuronally differentiated PC12 cells during ceramide-dependent cell death","volume":"426","author":"Muriel","year":"2000","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.lfs.2025.123478_bb0205","doi-asserted-by":"crossref","unstructured":"Polanco, C. M., Cavieres, V. A., Galarza, A. J., Jara, C., Torres, A. K., Cancino, J., Varas-Godoy, M., Burgos, P. V., Tapia-Rojas, C., & Mardones, G. A. (2024). GOLPH3 participates in mitochondrial fission and is necessary to sustain bioenergetic function in MDA-MB-231 breast Cancer cells. Cells, 13(4), 316. doi:https:\/\/doi.org\/10.3390\/cells13040316.","DOI":"10.3390\/cells13040316"},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0210","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/jcp.20606","article-title":"Differential subcellular distribution of glucose transporters GLUT1-6 and GLUT9 in human cancer: ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissues","volume":"207","author":"Godoy","year":"2006","journal-title":"J. Cell. Physiol."},{"issue":"9B","key":"10.1016\/j.lfs.2025.123478_bb0215","doi-asserted-by":"crossref","first-page":"3973","DOI":"10.1111\/j.1582-4934.2008.00544.x","article-title":"Nutritional channels in breast cancer","volume":"13","author":"Godoy","year":"2009","journal-title":"J. Cell. Mol. Med."},{"issue":"11","key":"10.1016\/j.lfs.2025.123478_bb0220","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1158\/0008-5472.CAN-19-0456","article-title":"Dietary fructose promotes prostate Cancer growth","volume":"81","author":"Carre\u00f1o","year":"2021","journal-title":"Cancer Res."},{"issue":"14","key":"10.1016\/j.lfs.2025.123478_bb0225","first-page":"3029","article-title":"MeCP2 co-ordinates liver lipid metabolism with the NCoR1\/HDAC3 corepressor complex","volume":"25","author":"Kyle","year":"2016","journal-title":"Hum. Mol. Genet."},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0230","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1161\/CIRCRESAHA.119.316306","article-title":"Role of mitochondrial calcium and the permeability transition pore in regulating cell death","volume":"126","author":"Bauer","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.lfs.2025.123478_bb0235","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.yjmcc.2020.05.013","article-title":"ATP synthase c-subunit ring as the channel of mitochondrial permeability transition: regulator of metabolism in development and degeneration","volume":"144","author":"Mnatsakanyan","year":"2020","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.lfs.2025.123478_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.jprot.2019.103537","article-title":"Brain protein changes in Mecp2 mouse mutant models: effects on disease progression of Mecp2 brain specific gene reactivation","volume":"210","author":"Cortelazzo","year":"2020","journal-title":"J. Proteomics"},{"issue":"31","key":"10.1016\/j.lfs.2025.123478_bb0245","doi-asserted-by":"crossref","first-page":"20796","DOI":"10.1074\/jbc.M109.025353","article-title":"Calcium elevation in mitochondria is the main Ca2+ requirement for mitochondrial permeability transition pore (mPTP) opening","volume":"284","author":"Baumgartner","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.lfs.2025.123478_bb0250","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.neuroscience.2015.07.012","article-title":"Alcohol hangover induces mitochondrial dysfunction and free radical production in mouse cerebellum","volume":"304","author":"Karadayian","year":"2015","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0255","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1042\/BJ20080321","article-title":"High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation","volume":"413","author":"Azzu","year":"2008","journal-title":"Biochem. J."},{"key":"10.1016\/j.lfs.2025.123478_bb0260","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/5358647","article-title":"Adenosine triphosphate promotes allergen-induced airway inflammation and Th17 cell polarization in neutrophilic asthma","volume":"2017","author":"Zhang","year":"2017","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.lfs.2025.123478_bb0265","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.63453","article-title":"The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging","volume":"10","author":"Angeli","year":"2021","journal-title":"eLife"},{"issue":"37","key":"10.1016\/j.lfs.2025.123478_bb0270","doi-asserted-by":"crossref","first-page":"19642","DOI":"10.1074\/jbc.M116.734814","article-title":"ATP\/ADP turnover and import of glycolytic ATP into mitochondria in Cancer cells is independent of the adenine nucleotide translocator","volume":"291","author":"Maldonado","year":"2016","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.lfs.2025.123478_bb0275","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/s42255-022-00591-z","article-title":"Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo","volume":"4","author":"Murphy","year":"2022","journal-title":"Nat. Metab."},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0280","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201948754","article-title":"The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis1","volume":"23","author":"Waters","year":"2022","journal-title":"EMBO Rep."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0285","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.stem.2018.05.021","article-title":"AMPK\/FIS1-mediated Mitophagy is required for self-renewal of human AML stem cells","volume":"23","author":"Pei","year":"2018","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.lfs.2025.123478_bb0290","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2020.580879","article-title":"Mitochondrial dynamics in the brain are associated with feeding, glucose homeostasis, and whole-body metabolism","volume":"11","author":"Haigh","year":"2020","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.lfs.2025.123478_bb0295","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2020.592129","article-title":"The molecular mechanisms underlying mitochondria-associated endoplasmic reticulum membrane-induced insulin resistance","volume":"11","author":"Cheng","year":"2020","journal-title":"Front. Endocrinol."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0300","doi-asserted-by":"crossref","first-page":"13063","DOI":"10.1038\/s41598-020-69913-z","article-title":"GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes","volume":"10","author":"Nicholas","year":"2020","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0305","first-page":"68","article-title":"Glucosa-6-fosfato deshidrogenasa (G6PD). Respuesta de los hemat\u00edes y otras c\u00e9lulas humanas a la disminuci\u00f3n en su actividad","volume":"38","author":"Bonilla","year":"2007"},{"issue":"4","key":"10.1016\/j.lfs.2025.123478_bb0310","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/82630","article-title":"Absence of perilipin results in leanness and reverses obesity in Lepr(db\/db) mice","volume":"26","author":"Martinez-Botas","year":"2000","journal-title":"Nat. Genet."},{"issue":"5","key":"10.1016\/j.lfs.2025.123478_bb0315","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0064605","article-title":"Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation","volume":"8","author":"Takahashi","year":"2013","journal-title":"PloS One"},{"issue":"8","key":"10.1016\/j.lfs.2025.123478_bb0320","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1172\/JCI119746","article-title":"Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene","volume":"100","author":"Shimano","year":"1997","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0325","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/bbrc.2001.5146","article-title":"Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity","volume":"285","author":"Thupari","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"8","key":"10.1016\/j.lfs.2025.123478_bb0330","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0023860","article-title":"The effect of ACACB cis-variants on gene expression and metabolic traits","volume":"6","author":"Ma","year":"2011","journal-title":"PloS One"},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0335","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s12017-014-8295-9","article-title":"Rett syndrome and MeCP2","volume":"16","author":"Liyanage","year":"2014","journal-title":"Neuromolecular Med."},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0340","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0022-3476(98)70436-6","article-title":"Increased energy expenditure associated with repetitive involuntary movement does not contribute to growth failure in girls with Rett syndrome","volume":"132","author":"Motil","year":"1998","journal-title":"J. Pediatr."},{"issue":"5","key":"10.1016\/j.lfs.2025.123478_bb0345","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1055\/s-0031-1287841","article-title":"Increased resting metabolic rate in girls with Rett syndrome compared to girls with developmental disabilities","volume":"42","author":"Platte","year":"2011","journal-title":"Neuropediatrics"},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0350","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/85899","article-title":"A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome","volume":"27","author":"Guy","year":"2001","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0355","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1186\/s12915-021-01190-2","article-title":"JNK signaling provides a novel therapeutic target for Rett syndrome","volume":"19","author":"Musi","year":"2021","journal-title":"BMC Biol."},{"issue":"8","key":"10.1016\/j.lfs.2025.123478_bb0360","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202152835","article-title":"Resident macrophages restrain pathological adipose tissue remodeling and protect vascular integrity in obese mice","volume":"22","author":"Chen","year":"2021","journal-title":"EMBO Rep."},{"issue":"10","key":"10.1016\/j.lfs.2025.123478_bb0365","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0109527","article-title":"Anaplerotic triheptanoin diet enhances mitochondrial substrate use to remodel the metabolome and improve lifespan, motor function, and sociability in MeCP2-null mice","volume":"9","author":"Park","year":"2014","journal-title":"PloS One"},{"issue":"6","key":"10.1016\/j.lfs.2025.123478_bb0370","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1073\/pnas.0610593104","article-title":"Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2","volume":"104","author":"Giacometti","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"5815","key":"10.1016\/j.lfs.2025.123478_bb0375","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1126\/science.1138389","article-title":"Reversal of neurological defects in a mouse model of Rett syndrome","volume":"315","author":"Guy","year":"2007","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.lfs.2025.123478_bb0380","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2021.113518","article-title":"Perinatal exposure to high fat diet alters expression of MeCP2 in the hypothalamus","volume":"415","author":"Frayre","year":"2021","journal-title":"Behav. Brain Res."},{"issue":"6","key":"10.1016\/j.lfs.2025.123478_bb0385","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.neuron.2008.07.030","article-title":"Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress","volume":"59","author":"Fyffe","year":"2008","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0390","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/s00125-013-3072-0","article-title":"Leptin resistance and obesity in mice with deletion of methyl-CpG-binding protein 2 (MeCP2) in hypothalamic pro-opiomelanocortin (POMC) neurons","volume":"57","author":"Wang","year":"2014","journal-title":"Diabetologia"},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0395","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210184","article-title":"High-fat diet accelerates extreme obesity with hyperphagia in female heterozygous Mecp2-null mice","volume":"14","author":"Fukuhara","year":"2019","journal-title":"PloS One"},{"key":"10.1016\/j.lfs.2025.123478_bb0400","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2024.114863","article-title":"POMC-specific knockdown of MeCP2 leads to adverse phenotypes in mice chronically exposed to high fat diet","volume":"461","author":"Frayre","year":"2024","journal-title":"Behav. Brain Res."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0405","first-page":"1","article-title":"Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus","volume":"9","author":"Burhans","year":"2018","journal-title":"Compr. Physiol."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0410","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1038\/s41467-017-01232-w","article-title":"Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation","volume":"8","author":"Shin","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.lfs.2025.123478_bb0415","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.576347","article-title":"Adipocyte ceramides-the Nexus of inflammation and metabolic disease","volume":"11","author":"Chaurasia","year":"2020","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0420","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jdermsci.2019.12.002","article-title":"The role of ceramides in skin homeostasis and inflammatory skin diseases","volume":"97","author":"Li","year":"2020","journal-title":"J. Dermatol. Sci."},{"issue":"6","key":"10.1016\/j.lfs.2025.123478_bb0425","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130183","article-title":"MeCP2 affects skeletal muscle growth and morphology through non cell-autonomous mechanisms","volume":"10","author":"Conti","year":"2015","journal-title":"PloS One"},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0430","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/s40795-022-00628-2","article-title":"Energy intake, expenditure and balance, and factors associated with energy balance of young adults (20-39 years): a retrospective cross-sectional community-based cohort study","volume":"8","author":"Ayogu","year":"2022","journal-title":"BMC Nutrition"},{"key":"10.1016\/j.lfs.2025.123478_bb0435","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.neuroscience.2012.09.078","article-title":"Mechanism of hyperphagia contributing to obesity in brain-derived neurotrophic factor knockout mice","volume":"229","author":"Fox","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.lfs.2025.123478_bb0440","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.14199","article-title":"Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders","volume":"5","author":"Meng","year":"2016","journal-title":"eLife"},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0445","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3390\/ijms19010097","article-title":"Motor, somatosensory, viscerosensory and metabolic impairments in a heterozygous female rat model of Rett syndrome","volume":"19","author":"Bhattacherjee","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.lfs.2025.123478_bb0450","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0026671","article-title":"Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretion","volume":"6","author":"Lou","year":"2011","journal-title":"PloS One"},{"issue":"8","key":"10.1016\/j.lfs.2025.123478_bb0455","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1038\/s42255-021-00432-5","article-title":"Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function","volume":"3","author":"Duquenne","year":"2021","journal-title":"Nat. Metab."},{"issue":"4","key":"10.1016\/j.lfs.2025.123478_bb0460","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1177\/1073858415585472","article-title":"Mitochondria: major regulators of neural development","volume":"22","author":"Xavier","year":"2016","journal-title":"The Neuroscientis"},{"key":"10.1016\/j.lfs.2025.123478_bb0465","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.redox.2018.07.010","article-title":"Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus","volume":"18","author":"Jara","year":"2018","journal-title":"Redox Biol."},{"key":"10.1016\/j.lfs.2025.123478_bb0470","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6626484","article-title":"Targeting the mitochondrial permeability transition pore to prevent age-associated cell damage and neurodegeneration","volume":"2021","author":"Kent","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"16","key":"10.1016\/j.lfs.2025.123478_bb0475","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1093\/hmg\/ddq214","article-title":"The MeCP2\/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis","volume":"19","author":"Forlani","year":"2010","journal-title":"Hum. Mol. Genet."},{"issue":"20","key":"10.1016\/j.lfs.2025.123478_bb0480","doi-asserted-by":"crossref","first-page":"7763","DOI":"10.1073\/pnas.0307083101","article-title":"Temporal and regional differences in the olfactory proteome as a consequence of MeCP2 deficiency","volume":"101","author":"Matarazzo","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.lfs.2025.123478_bb0485","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s12017-015-8363-9","article-title":"Astrocyte transcriptome from the Mecp2(308)-truncated mouse model of Rett syndrome","volume":"17","author":"Del\u00e9pine","year":"2015","journal-title":"Neuromolecular Med."},{"issue":"12","key":"10.1016\/j.lfs.2025.123478_bb0490","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.tibs.2016.09.001","article-title":"Calcium at the center of cell signaling: interplay between endoplasmic reticulum, mitochondria, and lysosomes","volume":"41","author":"Raffaello","year":"2016","journal-title":"Trends Biochem. Sci."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0495","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ydbio.2017.04.018","article-title":"Development or disease: duality of the mitochondrial permeability transition pore","volume":"426","author":"P\u00e9rez","year":"2017","journal-title":"Dev. Biol."},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0500","doi-asserted-by":"crossref","first-page":"298","DOI":"10.18388\/pb.2016_29","article-title":"From mitochondrial large amplitude swelling to the permeability transition - a short historic overview. Od p\u0119cznienia mitochondri\u00f3w po koncepcj\u0119 transformacji przepuszczalno\u015bciowej - kr\u00f3tki zarys historyczny","volume":"62","author":"Wojtczak","year":"2016","journal-title":"Postepy Biochem."},{"issue":"1\u20132","key":"10.1016\/j.lfs.2025.123478_bb0505","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.yexcr.2018.10.009","article-title":"Electron microscopy techniques employed to explore mitochondrial defects in the developing rat brain following ketamine treatment","volume":"373","author":"Eustaquio","year":"2018","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.lfs.2025.123478_bb0510","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.mito.2017.08.004","article-title":"Different approaches to modeling analysis of mitochondrial swelling","volume":"38","author":"Javadov","year":"2018","journal-title":"Mitochondrion"},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0515","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.bbrc.2005.12.080","article-title":"Brain magnetic resonance study of Mecp2 deletion effects on anatomy and metabolism","volume":"340","author":"Saywell","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.lfs.2025.123478_bb0520","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.neuropharm.2017.04.024","article-title":"Stimulation of the brain serotonin receptor 7 rescues mitochondrial dysfunction in female mice from two models of Rett syndrome","volume":"121","author":"Valenti","year":"2017","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.lfs.2025.123478_bb0525","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.freeradbiomed.2015.02.014","article-title":"Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1","volume":"83","author":"De Filippis","year":"2015","journal-title":"Free Radic. Biol. Med."},{"issue":"2","key":"10.1016\/j.lfs.2025.123478_bb0530","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1152\/jn.91124.2008","article-title":"Enhanced hypoxia susceptibility in hippocampal slices from a mouse model of rett syndrome","volume":"101","author":"Fischer","year":"2009","journal-title":"J. Neurophysiol."},{"issue":"9","key":"10.1016\/j.lfs.2025.123478_bb0535","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.3390\/cells10092494","article-title":"Metabolomic fingerprint of Mecp2-deficient mouse cortex: evidence for a pronounced multi-facetted metabolic component in Rett syndrome","volume":"10","author":"Golubiani","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.lfs.2025.123478_bb0540","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3389\/fncel.2014.00056","article-title":"The free radical scavenger Trolox dampens neuronal hyperexcitability, reinstates synaptic plasticity, and improves hypoxia tolerance in a mouse model of Rett syndrome","volume":"8","author":"Janc","year":"2014","journal-title":"Front. Cell. Neurosci."},{"issue":"10 Pt A","key":"10.1016\/j.lfs.2025.123478_bb0545","doi-asserted-by":"crossref","first-page":"2066","DOI":"10.1016\/j.bbadis.2015.07.014","article-title":"Impaired enzymatic defensive activity, mitochondrial dysfunction and proteasome activation are involved in RTT cell oxidative damage","volume":"1852","author":"Cervellati","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"issue":"4","key":"10.1016\/j.lfs.2025.123478_bb0550","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.stem.2013.09.001","article-title":"Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons","volume":"13","author":"Li","year":"2013","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.lfs.2025.123478_bb0555","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/8416763","article-title":"Oxidative stress: harms and benefits for human health","volume":"2017","author":"Pizzino","year":"2017","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0560","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1172\/JCI200317741","article-title":"Neuronal degeneration and mitochondrial dysfunction","volume":"111","author":"Schon","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.lfs.2025.123478_bb0565","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1146\/annurev.biochem.76.052305.091720","article-title":"Mitochondrial-nuclear communications","volume":"76","author":"Ryan","year":"2007","journal-title":"Annu. Rev. Biochem."},{"issue":"10","key":"10.1016\/j.lfs.2025.123478_bb0570","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.recesp.2011.05.018","article-title":"Din\u00e1mica mitocondrial: un potencial nuevo blanco terap\u00e9utico para la insuficiencia cardiaca [Mitochondrial dynamics: a potential new therapeutic target for heart failure]","volume":"64","author":"Kuzmicic","year":"2011","journal-title":"Revista espanola de cardiologia"},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0575","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1172\/JCI59660","article-title":"Obesity is associated with hypothalamic injury in rodents and humans","volume":"122","author":"Thaler","year":"2012","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0580","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.cell.2013.09.004","article-title":"Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity","volume":"155","author":"Dietrich","year":"2013","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0585","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.cell.2013.09.003","article-title":"Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance","volume":"155","author":"Schneeberger","year":"2013","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0590","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.cmet.2017.01.003","article-title":"DRP1 suppresses leptin and glucose sensing of POMC neurons","volume":"25","author":"Santoro","year":"2017","journal-title":"Cell Metab."},{"key":"10.1016\/j.lfs.2025.123478_bb0595","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.molmet.2018.11.007","article-title":"Mitochondrial dynamin-related protein 1 (DRP1) translocation in response to cerebral glucose is impaired in a rat model of early alteration in hypothalamic glucose sensing","volume":"20","author":"Desmoulins","year":"2019","journal-title":"Molecular Metabolism"},{"issue":"6","key":"10.1016\/j.lfs.2025.123478_bb0600","doi-asserted-by":"crossref","first-page":"E731","DOI":"10.1152\/ajpendo.00159.2011","article-title":"Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes","volume":"302","author":"Holmstr\u00f6m","year":"2012","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.lfs.2025.123478_bb0605","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2021.108790","article-title":"Impaired mitochondrial quality control in Rett syndrome","volume":"700","author":"Crivellari","year":"2021","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.lfs.2025.123478_bb0610","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.freeradbiomed.2020.05.014","article-title":"Proteomic profiling reveals mitochondrial alterations in Rett syndrome","volume":"155","author":"Cicaloni","year":"2020","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.lfs.2025.123478_bb0615","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/3064016","article-title":"Increased mitochondrial mass and cytosolic redox imbalance in hippocampal astrocytes of a mouse model of Rett syndrome: subcellular changes revealed by ratiometric imaging of JC-1 and roGFP1 fluorescence","volume":"2017","author":"Bebensee","year":"2017","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.lfs.2025.123478_bb0620","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.660095","article-title":"Mitochondrial fission protein 1: emerging roles in organellar form and function in health and disease","volume":"12","author":"Ihenacho","year":"2021","journal-title":"Front. Endocrinol."},{"issue":"10","key":"10.1016\/j.lfs.2025.123478_bb0625","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1089\/ars.2010.3779","article-title":"The interplay between mitochondrial dynamics and mitophagy","volume":"14","author":"Twig","year":"2011","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.lfs.2025.123478_bb0630","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.freeradbiomed.2016.04.015","article-title":"Mechanisms of mitophagy: PINK1, Parkin, USP30 and beyond","volume":"100","author":"Bingol","year":"2016","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0635","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13024-020-00367-7","article-title":"PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson\u2019s disease","volume":"15","author":"Ge","year":"2020","journal-title":"Mol. Neurodegener."},{"issue":"1","key":"10.1016\/j.lfs.2025.123478_bb0640","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111942","article-title":"Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation","volume":"42","author":"Sun","year":"2023","journal-title":"Cell Rep."},{"issue":"94","key":"10.1016\/j.lfs.2025.123478_bb0645","doi-asserted-by":"crossref","first-page":"94ra70","DOI":"10.1126\/scitranslmed.3002394","article-title":"Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality","volume":"3","author":"Chan","year":"2011","journal-title":"Sci. Transl. Med."},{"issue":"22","key":"10.1016\/j.lfs.2025.123478_bb0650","doi-asserted-by":"crossref","first-page":"7233","DOI":"10.1073\/pnas.81.22.7233","article-title":"Identification and characterization of the glucose transporter of the blood-brain barrier by cytochalasin B binding and immunological reactivity","volume":"81","author":"Dick","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"11","key":"10.1016\/j.lfs.2025.123478_bb0655","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1001\/jamaneurol.2013.3090","article-title":"Cerebrospinal fluid analysis in the workup of GLUT1 deficiency syndrome: a systematic review","volume":"70","author":"Leen","year":"2013","journal-title":"JAMA Neurol."},{"issue":"3","key":"10.1016\/j.lfs.2025.123478_bb0660","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/ajh.2830200302","article-title":"Characteristics of hexokinase, pyruvate kinase, and glucose-6-phosphate dehydrogenase during adult and neonatal reticulocyte maturation","volume":"20","author":"Jansen","year":"1985","journal-title":"Am. J. Hematol."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320525001110?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320525001110?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T12:34:32Z","timestamp":1741264472000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320525001110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":132,"alternative-id":["S0024320525001110"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2025.123478","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The methyl-CpG-binding protein 2 (Mecp2) regulates the hypothalamic mitochondrial function and white adipose tissue lipid metabolism","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2025.123478","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"123478"}}