{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T05:59:59Z","timestamp":1784527199755,"version":"3.55.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002597","name":"Kyung Hee University","doi-asserted-by":"publisher","award":["GS-1-JO-NON-20240414"],"award-info":[{"award-number":["GS-1-JO-NON-20240414"]}],"id":[{"id":"10.13039\/501100002597","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Korea Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HF22C0077"],"award-info":[{"award-number":["HF22C0077"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.lfs.2026.124201","type":"journal-article","created":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T07:02:25Z","timestamp":1768114945000},"page":"124201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Sinapic acid balances the excitatory and inhibitory neurotransmitter systems to mitigate post-traumatic stress disorder-like behaviors"],"prefix":"10.1016","volume":"388","author":[{"given":"Chang Hyeon","family":"Kong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keontae","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju Eun","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho Jung","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Jin","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seo Yun","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Hoon","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.lfs.2026.124201_bb0005","first-page":"273","article-title":"Posttraumatic stress disorder: evaluation and treatment","volume":"107","author":"Sartor","year":"2023","journal-title":"Am. Fam. Physician"},{"key":"10.1016\/j.lfs.2026.124201_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.janxdis.2021.102475","article-title":"Positive emotion dysregulation and posttraumatic stress disorder symptoms: investigating the role of anxiety sensitivity","volume":"84","author":"Raudales","year":"2021","journal-title":"J. Anxiety Disord."},{"issue":"3","key":"10.1016\/j.lfs.2026.124201_bb0015","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1515\/mr-2022-0012","article-title":"Post-traumatic stress disorder: a psychiatric disorder requiring urgent attention","volume":"2","author":"Du","year":"2022","journal-title":"Med. Rev. (2021)"},{"issue":"1","key":"10.1016\/j.lfs.2026.124201_bb0020","article-title":"Pharmacological therapy for post-traumatic stress disorder: a systematic review and meta-analysis of monotherapy, augmentation and head-to-head approaches","volume":"12","author":"Hoskins","year":"2021","journal-title":"Eur. J. Psychotraumatol."},{"issue":"3","key":"10.1016\/j.lfs.2026.124201_bb0025","article-title":"Attempted \u201csuicide by police\u201d by a patient with bipolar I disorder and PTSD on paroxetine monotherapy","volume":"24","author":"Condiotte","year":"2022","journal-title":"Prim. Care Companion CNS Disord."},{"issue":"19","key":"10.1016\/j.lfs.2026.124201_bb0030","doi-asserted-by":"crossref","first-page":"3226","DOI":"10.1111\/bph.13843","article-title":"Neurosteroid biosynthesis down-regulation and changes in GABA(A) receptor subunit composition: a biomarker axis in stress-induced cognitive and emotional impairment","volume":"174","author":"Locci","year":"2017","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.lfs.2026.124201_bb0035","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00213-018-5022-5","article-title":"N-Methyl D-aspartate receptor subunit signaling in fear extinction","volume":"236","author":"Radulovic","year":"2019","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.lfs.2026.124201_bb0040","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.neulet.2016.11.064","article-title":"Glutamate dysregulation and glutamatergic therapeutics for PTSD: evidence from human studies","volume":"649","author":"Averill","year":"2017","journal-title":"Neurosci. Lett."},{"issue":"2","key":"10.1016\/j.lfs.2026.124201_bb0045","first-page":"131","article-title":"GABA-receptors in modulation of fear memory extinction","volume":"66","author":"Dubrovina","year":"2016","journal-title":"Zh. Vyssh. Nerv. Deiat. Im. I. P. Pavlova"},{"issue":"7","key":"10.1016\/j.lfs.2026.124201_bb0050","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1017\/S1092852900016862","article-title":"The role of the glutamatergic system in posttraumatic stress disorder","volume":"13","author":"Nair","year":"2008","journal-title":"CNS Spectr."},{"issue":"11","key":"10.1016\/j.lfs.2026.124201_bb0055","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1038\/s41386-023-01606-3","article-title":"Long term structural and functional neural changes following a single infusion of ketamine in PTSD","volume":"48","author":"Duek","year":"2023","journal-title":"Neuropsychopharmacology"},{"issue":"13","key":"10.1016\/j.lfs.2026.124201_bb0060","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1038\/s41386-021-01104-4","article-title":"Neuroimaging correlates and predictors of response to repeated-dose intravenous ketamine in PTSD: preliminary evidence","volume":"46","author":"Norbury","year":"2021","journal-title":"Neuropsychopharmacology"},{"issue":"11","key":"10.1016\/j.lfs.2026.124201_bb0065","first-page":"1108","article-title":"Neurophysiological and clinical effects of the NMDA receptor antagonist lanicemine (BHV-5500) in PTSD: a randomized, double-blind, placebo-controlled trial, Depress","volume":"38","author":"Ramakrishnan","year":"2021","journal-title":"Anxiety"},{"key":"10.1016\/j.lfs.2026.124201_bb0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2022.114486","article-title":"Ifenprodil tartrate treatment of adolescents with post-traumatic stress disorder: a double-blind, placebo-controlled trial","volume":"311","author":"Sasaki","year":"2022","journal-title":"Psychiatry Res."},{"issue":"3","key":"10.1016\/j.lfs.2026.124201_bb0075","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1523\/JNEUROSCI.3273-12.2013","article-title":"Double dissociation of the requirement for GluN2B- and GluN2A-containing NMDA receptors in the destabilization and restabilization of a reconsolidating memory","volume":"33","author":"Milton","year":"2013","journal-title":"J. Neurosci."},{"issue":"6","key":"10.1016\/j.lfs.2026.124201_bb0080","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1007\/s00406-020-01223-x","article-title":"Pharmacotherapy of 1,044 inpatients with posttraumatic stress disorder: current status and trends in German-speaking countries","volume":"271","author":"Reinhard","year":"2021","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.lfs.2026.124201_bb0085","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.psyneuen.2018.04.024","article-title":"PTSD in women is associated with a block in conversion of progesterone to the GABAergic neurosteroids allopregnanolone and pregnanolone measured in plasma","volume":"93","author":"Pineles","year":"2018","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.lfs.2026.124201_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2020.100225","article-title":"Associations between PTSD-related extinction retention deficits in women and plasma steroids that modulate brain GABA(A) and NMDA receptor activity","volume":"13","author":"Pineles","year":"2020","journal-title":"Neurobiol. Stress"},{"issue":"7","key":"10.1016\/j.lfs.2026.124201_bb0095","article-title":"The emerging role of neurosteroids: novel drugs brexanalone, sepranolone, zuranolone, and ganaxolone in mood and neurological disorders","volume":"16","author":"Singhal","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.lfs.2026.124201_bb0100","doi-asserted-by":"crossref","DOI":"10.1021\/acschemneuro.4c00349","article-title":"Pharmacological activities and molecular mechanisms of sinapic acid in neurological disorders","author":"Farzan","year":"2024","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.lfs.2026.124201_bb0105","doi-asserted-by":"crossref","DOI":"10.1007\/s10753-024-02019-0","article-title":"Sinapic acid mitigates pentylenetetrazol-induced acute seizures by modulating the NLRP3 inflammasome and regulating calcium\/calcineurin signaling: in vivo and in silico approaches","author":"Ali","year":"2024","journal-title":"Inflammation"},{"issue":"2","key":"10.1016\/j.lfs.2026.124201_bb0110","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/adb.12343","article-title":"Re-exposure to morphine-associated context facilitated long-term potentiation in the vSUB-NAc glutamatergic pathway via GluN2B-containing receptor activation","volume":"22","author":"Li","year":"2017","journal-title":"Addict. Biol."},{"issue":"3","key":"10.1016\/j.lfs.2026.124201_bb0115","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1097\/ALN.0000000000000532","article-title":"GABAergic inhibition regulated pain sensitization through STEP61 signaling in spinal dorsal horn of mice","volume":"122","author":"Li","year":"2015","journal-title":"Anesthesiology"},{"issue":"1\u20132","key":"10.1016\/j.lfs.2026.124201_bb0120","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.neuropharm.2010.03.012","article-title":"Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice","volume":"59","author":"Kim","year":"2010","journal-title":"Neuropharmacology"},{"issue":"3","key":"10.1016\/j.lfs.2026.124201_bb0125","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.lfs.2007.05.007","article-title":"Anxiolytic-like effects of sinapic acid in mice","volume":"81","author":"Yoon","year":"2007","journal-title":"Life Sci."},{"issue":"6","key":"10.1016\/j.lfs.2026.124201_bb0130","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0306-4530(97)00045-0","article-title":"Effects of stress and glucocorticoids on CNS oxytocin receptor binding","volume":"22","author":"Liberzon","year":"1997","journal-title":"Psychoneuroendocrinology"},{"issue":"12","key":"10.1016\/j.lfs.2026.124201_bb0135","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1002\/da.20629","article-title":"Single prolonged stress: toward an animal model of posttraumatic stress disorder","volume":"26","author":"Yamamoto","year":"2009","journal-title":"Depress. Anxiety"},{"key":"10.1016\/j.lfs.2026.124201_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainresbull.2023.110697","article-title":"The potential role of GSK-3\u03b2 signaling pathway for amelioration actions of ketamine on the PTSD rodent model","volume":"200","author":"Hu","year":"2023","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.lfs.2026.124201_bb0145","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3389\/fnbeh.2019.00018","article-title":"Single-prolonged stress impairs prefrontal cortex control of amygdala and striatum in rats","volume":"13","author":"Piggott","year":"2019","journal-title":"Front. Behav. Neurosci."},{"issue":"4","key":"10.1016\/j.lfs.2026.124201_bb0150","doi-asserted-by":"crossref","first-page":"303","DOI":"10.4103\/0976-500X.119726","article-title":"How to calculate sample size in animal studies?","volume":"4","author":"Charan","year":"2013","journal-title":"J. Pharmacol. Pharmacother."},{"key":"10.1016\/j.lfs.2026.124201_bb0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2024.110990","article-title":"D-Pinitol mitigates post-traumatic stress disorder-like behaviors induced by single prolonged stress in mice through mineralocorticoid receptor antagonism","author":"Kong","year":"2024","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.lfs.2026.124201_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118270","article-title":"Cheonwangbosimdan mitigates post-traumatic stress disorder-like behaviors through GluN2B-containing NMDA receptor antagonism in mice","volume":"330","author":"Kong","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.lfs.2026.124201_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.123271","article-title":"4-Methoxycinnamic acid ameliorates post-traumatic stress disorder-like behavior in mice by antagonizing the CRF type 1 receptor","volume":"361","author":"Jeon","year":"2025","journal-title":"Life Sci."},{"key":"10.1016\/j.lfs.2026.124201_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.175954","article-title":"Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice","author":"Kong","year":"2023","journal-title":"Eur. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.lfs.2026.124201_bb0175","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/HRP.0000000000000185","article-title":"Functional neuroanatomy of emotion and its regulation in PTSD","volume":"26","author":"Fitzgerald","year":"2018","journal-title":"Harv. Rev. Psychiatry"},{"issue":"6","key":"10.1016\/j.lfs.2026.124201_bb0180","first-page":"1738","article-title":"Posttraumatic stress disorder and anxiety-related conditions","volume":"27","author":"Williamson","year":"2021","journal-title":"Continuum (Minneap Minn.)"},{"key":"10.1016\/j.lfs.2026.124201_bb0185","article-title":"Involvement of the GABAergic system in PTSD and its therapeutic significance","volume":"16","author":"Huang","year":"2023","journal-title":"Front. Mol. Neurosci."},{"issue":"5","key":"10.1016\/j.lfs.2026.124201_bb0190","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/s41386-021-01197-x","article-title":"Regional specificity and clinical correlates of cortical GABA alterations in posttraumatic stress disorder","volume":"47","author":"Rosso","year":"2022","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.lfs.2026.124201_bb0195","article-title":"Medial prefrontal cortex neurotransmitter abnormalities in posttraumatic stress disorder with and without comorbidity to major depression","volume":"5220","author":"Swanberg","year":"2024","journal-title":"NMR Biomed."},{"issue":"4","key":"10.1016\/j.lfs.2026.124201_bb0200","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1007\/s12640-019-0006-8","article-title":"Salicylate-induced ototoxicity of spiral ganglion neurons: Ca(2+)\/CaMKII-mediated interaction between NMDA receptor and GABA(A) receptor","volume":"35","author":"Qin","year":"2019","journal-title":"Neurotox. Res."},{"issue":"6","key":"10.1016\/j.lfs.2026.124201_bb0205","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1038\/nn.2806","article-title":"NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents","volume":"14","author":"Lee","year":"2011","journal-title":"Nat. Neurosci."},{"issue":"16","key":"10.1016\/j.lfs.2026.124201_bb0210","doi-asserted-by":"crossref","first-page":"5893","DOI":"10.1523\/JNEUROSCI.5938-10.2011","article-title":"NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling","volume":"31","author":"Szabadits","year":"2011","journal-title":"J. Neurosci."},{"issue":"38","key":"10.1016\/j.lfs.2026.124201_bb0215","doi-asserted-by":"crossref","first-page":"16679","DOI":"10.1073\/pnas.1000589107","article-title":"NMDA receptors regulate GABAA receptor lateral mobility and clustering at inhibitory synapses through serine 327 on the \u03b32 subunit","volume":"107","author":"Muir","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"6","key":"10.1016\/j.lfs.2026.124201_bb0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109960","article-title":"Distinct regulation of tonic GABAergic inhibition by NMDA receptor subtypes","volume":"37","author":"Wu","year":"2021","journal-title":"Cell Rep."},{"issue":"24","key":"10.1016\/j.lfs.2026.124201_bb0225","doi-asserted-by":"crossref","first-page":"8851","DOI":"10.1523\/JNEUROSCI.0979-11.2011","article-title":"GABAA receptor endocytosis in the basolateral amygdala is critical to the reinstatement of fear memory measured by fear-potentiated startle","volume":"31","author":"Lin","year":"2011","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.lfs.2026.124201_bb0230","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/s41386-021-01155-7","article-title":"Prefrontal cortex, amygdala, and threat processing: implications for PTSD","volume":"47","author":"Alexandra Kredlow","year":"2022","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.lfs.2026.124201_bb0235","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2023.1228056","article-title":"Hypothalamic orexins as possible therapeutic agents in threat and spatial memory disorders","volume":"17","author":"Mazur","year":"2023","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.lfs.2026.124201_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2018.11.032","article-title":"Orexin as a modulator of fear-related behavior: hypothalamic control of noradrenaline circuit","volume":"1731","author":"Soya","year":"2020","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.lfs.2026.124201_bb0245","doi-asserted-by":"crossref","first-page":"6403","DOI":"10.1038\/s41467-022-33828-2","article-title":"Aversive memory formation in humans involves an amygdala-hippocampus phase code","volume":"13","author":"Costa","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.lfs.2026.124201_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.nlm.2021.107490","article-title":"Amygdala-hippocampal interactions in synaptic plasticity and memory formation","volume":"184","author":"Roesler","year":"2021","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.lfs.2026.124201_bb0255","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0079-6123(07)67003-4","article-title":"Amygdala modulation of memory-related processes in the hippocampus: potential relevance to PTSD","volume":"167","author":"Tsoory","year":"2008","journal-title":"Prog. Brain Res."},{"issue":"9","key":"10.1016\/j.lfs.2026.124201_bb0260","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1002\/jnr.23604","article-title":"GluN2B-containing N-methyl-D-aspartate receptors compensate for the inhibitory control of synaptic plasticity during the early critical period in the rat visual cortex","volume":"93","author":"Lee","year":"2015","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.lfs.2026.124201_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.addicn.2024.100182","article-title":"Oral fentanyl consumption and withdrawal impairs fear extinction learning and enhances basolateral amygdala principal neuron excitatory-inhibitory balance in male and female mice","volume":"13","author":"Downs","year":"2024","journal-title":"Addict. Neurosci."},{"key":"10.1016\/j.lfs.2026.124201_bb0270","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jad.2025.03.127","article-title":"Uncoupling serotonin (2C) and dopamine (D2) receptor heterodimers ameliorate PTSD-like behaviors","volume":"380","author":"Li","year":"2025","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.lfs.2026.124201_bb0275","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/s41398-020-0806-x","article-title":"Rodent models of post-traumatic stress disorder: behavioral assessment","volume":"10","author":"Verbitsky","year":"2020","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.lfs.2026.124201_bb0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.tiv.2024.105977","article-title":"Sinapic acid alleviates glutamate-induced excitotoxicity by inhibiting neuroinflammation and endoplasmic reticulum stress pathway in C6 glioma cells","volume":"103","author":"Ortasoz","year":"2025","journal-title":"Toxicol. in Vitro"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320526000093?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320526000093?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T14:23:04Z","timestamp":1769610184000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320526000093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":56,"alternative-id":["S0024320526000093"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2026.124201","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sinapic acid balances the excitatory and inhibitory neurotransmitter systems to mitigate post-traumatic stress disorder-like behaviors","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2026.124201","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"124201"}}