{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T09:02:03Z","timestamp":1784710923656,"version":"3.55.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.lfs.2026.124443","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T15:25:35Z","timestamp":1778167535000},"page":"124443","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Inhalation of hydrogen gas reduces exacerbations of acute aortic dissection in mice"],"prefix":"10.1016","volume":"397","author":[{"given":"Masumi","family":"Iketani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Kawata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuroh","family":"Ohsawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Takayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Aokage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2026.124443_bb0005","doi-asserted-by":"crossref","DOI":"10.4414\/smw.2017.14489","article-title":"Acute aortic dissection: pathogenesis, risk factors and diagnosis","volume":"147","author":"Gawinecka","year":"2017","journal-title":"Swiss Med. Wkly."},{"key":"10.1016\/j.lfs.2026.124443_bb0010","doi-asserted-by":"crossref","first-page":"582","DOI":"10.21037\/acs.2017.11.03","article-title":"Differences in manifestations of Marfan syndrome, Ehlers-Danlos syndrome, and Loeys-Dietz syndrome","volume":"6","author":"Meester","year":"2017","journal-title":"Ann. Cardiothorac. Surg."},{"key":"10.1016\/j.lfs.2026.124443_bb0015","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1097\/GIM.0b013e3181e074f0","article-title":"Hereditary disorders of connective tissue: a guide to the emerging differential diagnosis","volume":"12","author":"Murphy-Ryan","year":"2010","journal-title":"Genet. Med."},{"key":"10.1016\/j.lfs.2026.124443_bb0020","doi-asserted-by":"crossref","DOI":"10.2174\/1573403X16666201014142930","article-title":"Aortic dissection: a review of the pathophysiology, management and prospective advances","volume":"17","author":"Sayed","year":"2021","journal-title":"Curr. Cardiol. Rev."},{"key":"10.1016\/j.lfs.2026.124443_bb0025","doi-asserted-by":"crossref","first-page":"16071","DOI":"10.1038\/nrdp.2016.71","article-title":"Aortic dissection","volume":"2","author":"Nienaber","year":"2016","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.lfs.2026.124443_bb0030","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.ajem.2021.10.016","article-title":"Management of acute aortic syndromes from initial presentation to definitive treatment","volume":"51","author":"Mehta","year":"2022","journal-title":"Am. J. Emerg. Med."},{"key":"10.1016\/j.lfs.2026.124443_bb0035","doi-asserted-by":"crossref","first-page":"22","DOI":"10.29245\/2578-3009\/2018\/4.1156","article-title":"Inflammatory mechanisms contributing to aortic expansion and rupture after acute aortic dissection","volume":"2","author":"Anzai","year":"2018","journal-title":"J. Immunol. Sci."},{"key":"10.1016\/j.lfs.2026.124443_bb0040","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.1161\/CIRCULATIONAHA.112.097097","article-title":"Neutrophil-derived matrix metalloproteinase 9 triggers acute aortic dissection","volume":"126","author":"Kurihara","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2026.124443_bb0045","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1161\/CIRCRESAHA.116.304918","article-title":"Adventitial CXCL1\/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture","volume":"116","author":"Anzai","year":"2015","journal-title":"Circ. Res."},{"key":"10.1016\/j.lfs.2026.124443_bb0050","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1007\/s11739-023-03309-5","article-title":"Therapeutic inhibition of CXCR1\/2: where do we stand?","volume":"18","author":"Sitaru","year":"2023","journal-title":"Intern. Emerg. Med."},{"key":"10.1016\/j.lfs.2026.124443_bb0055","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/nrd4390","article-title":"Is there new hope for therapeutic matrix metalloproteinase inhibition?","volume":"13","author":"Vandenbroucke","year":"2014","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.lfs.2026.124443_bb0060","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/nri2356","article-title":"Colony-stimulating factors in inflammation and autoimmunity","volume":"8","author":"Hamilton","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.lfs.2026.124443_bb0065","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bbrc.2008.05.165","article-title":"Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia\u2013reperfusion injury","volume":"373","author":"Hayashida","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.lfs.2026.124443_bb0070","doi-asserted-by":"crossref","first-page":"324","DOI":"10.2174\/1570159X14666160607205417","article-title":"Molecular hydrogen as a neuroprotective agent","volume":"15","author":"Iketani","year":"2017","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.lfs.2026.124443_bb0075","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/nm1577","article-title":"Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals","volume":"13","author":"Ohsawa","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.lfs.2026.124443_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2023.101907","article-title":"Efficacy of inhaled hydrogen on neurological outcome following brain ischaemia during post-cardiac arrest care (HYBRID II): a multi-centre, randomised, double-blind, placebo-controlled trial","volume":"58","author":"Tamura","year":"2023","journal-title":"eClinicalMedicine"},{"key":"10.1016\/j.lfs.2026.124443_bb0085","article-title":"The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury","volume":"21","author":"Aokage","year":"2021","journal-title":"BMC Pulmon. Med."},{"key":"10.1016\/j.lfs.2026.124443_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2023.112270","article-title":"Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2% hydrogen gas inhalation: a potential therapeutic strategy for geriatric inflammation and survival","volume":"180","author":"Aokage","year":"2023","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.lfs.2026.124443_bb0095","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.neulet.2009.02.016","article-title":"Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson\u2019s disease","volume":"453","author":"Fu","year":"2009","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.lfs.2026.124443_bb0100","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/SHK.0000000000000810","article-title":"Preadministration of hydrogen-rich water protects against lipopolysaccharide-induced sepsis and attenuates liver injury","volume":"48","author":"Iketani","year":"2017","journal-title":"Shock"},{"key":"10.1016\/j.lfs.2026.124443_bb0105","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-35239-0","article-title":"Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice","volume":"8","author":"Iketani","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2026.124443_bb0110","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pharmthera.2014.04.006","article-title":"Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine","volume":"144","author":"Ohta","year":"2014","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.lfs.2026.124443_bb0115","doi-asserted-by":"crossref","first-page":"650","DOI":"10.2174\/1381612826666201221150857","article-title":"Hydrogen gas therapy: from preclinical studies to clinical trials","volume":"27","author":"Sano","year":"2021","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.lfs.2026.124443_bb0120","doi-asserted-by":"crossref","first-page":"4243","DOI":"10.1111\/jcmm.13704","article-title":"Hydrogen gas inhalation protects against cutaneous ischaemia\/reperfusion injury in a mouse model of pressure ulcer","volume":"22","author":"Fang","year":"2018","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.lfs.2026.124443_bb0125","article-title":"Hydrogen attenuates endotoxin-induced lung injury by activating Thioredoxin 1 and decreasing tissue factor expression","volume":"12","author":"Li","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.lfs.2026.124443_bb0130","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1161\/01.ATV.0000085631.76095.64","article-title":"Aortic dissection precedes formation of aneurysms and atherosclerosis in angiotensin II-infused, apolipoprotein E-deficient mice","volume":"23","author":"Saraff","year":"2003","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.lfs.2026.124443_bb0135","doi-asserted-by":"crossref","first-page":"3637","DOI":"10.1172\/JCI38308","article-title":"An adventitial IL-6\/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice","volume":"119","author":"Tieu","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.lfs.2026.124443_bb0140","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0002-9149(70)90006-8","article-title":"Cystic medial necrosis of the ascending aorta in relation to age and hypertension","volume":"25","author":"Carlson","year":"1970","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.lfs.2026.124443_bb0145","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0002-9149(77)80004-0","article-title":"Histologic changes in the normal aging aorta: implications for dissecting aortic aneurysm","volume":"39","author":"Schlatmann","year":"1977","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.lfs.2026.124443_bb0150","first-page":"5125","article-title":"Experimental in vivo and ex vivo models for the study of human aortic dissection: promises and challenges","volume":"8","author":"Jiang","year":"2016","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.lfs.2026.124443_bb0155","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1111\/jnc.16142","article-title":"Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation","volume":"168","author":"Iketani","year":"2024","journal-title":"J. Neurochem."},{"key":"10.1016\/j.lfs.2026.124443_bb0160","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1538\/expanim.60.481","article-title":"Effect of three types of mixed anesthetic agents alternate to ketamine in mice","volume":"60","author":"Kawai","year":"2011","journal-title":"Exp. Anim."},{"key":"10.1016\/j.lfs.2026.124443_bb0165","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1189\/jlb.0113014","article-title":"Ly6 family proteins in neutrophil biology","volume":"94","author":"Lee","year":"2013","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.lfs.2026.124443_bb0170","doi-asserted-by":"crossref","first-page":"20173","DOI":"10.1038\/s41598-020-77349-8","article-title":"Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension","volume":"10","author":"Sugai","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2026.124443_bb0175","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/s41598-024-84117-5","article-title":"Influence of false lumen status on systemic inflammatory response triggered by acute aortic dissection","volume":"15","author":"Kimura","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2026.124443_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.vph.2024.107420","article-title":"Matrix metalloproteinases in aortic dissection","volume":"156","author":"Zhou","year":"2024","journal-title":"Vasc. Pharmacol."},{"key":"10.1016\/j.lfs.2026.124443_bb0185","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.cca.2011.09.029","article-title":"Plasma concentrations of interleukin-6, C-reactive protein, tumor necrosis factor-\u03b1 and matrix metalloproteinase-9 in aortic dissection","volume":"413","author":"Wen","year":"2012","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.lfs.2026.124443_bb0190","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/ehf2.14552","article-title":"D-dimer, C-reactive protein and matrix metalloproteinase 9 for prediction of type A aortic dissection patient survival","volume":"11","author":"Huang","year":"2023","journal-title":"ESC Heart Fail."},{"key":"10.1016\/j.lfs.2026.124443_bb0195","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.112.003459","article-title":"H2 gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model","volume":"1","author":"Hayashida","year":"2012","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.lfs.2026.124443_bb0200","first-page":"5197","article-title":"Inhalation of hydrogen gas reduces liver injury during major hepatotectomy in swine","volume":"18","author":"Xiang","year":"2012","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.lfs.2026.124443_bb0205","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.intimp.2014.06.001","article-title":"Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study","volume":"21","author":"Ishibashi","year":"2014","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.lfs.2026.124443_bb0210","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1182\/blood-2007-07-099648","article-title":"The coordinated action of G-CSF and ELR\u00a0+\u00a0CXC chemokines in neutrophil mobilization during acute inflammation","volume":"111","author":"Wengner","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.lfs.2026.124443_bb0215","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.biopha.2018.09.129","article-title":"Mechanical stretch aggravates aortic dissection by regulating MAPK pathway and the expression of MMP-9 and inflammation factors","volume":"108","author":"Hu","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.lfs.2026.124443_bb0220","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s12974-022-02670-0","article-title":"Hydrogen attenuates postoperative pain through Trx1\/ASK1\/MMP9 signaling pathway","volume":"20","author":"Li","year":"2023","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.lfs.2026.124443_bb0225","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1097\/PAS.0b013e318294adc3","article-title":"Acute medial dissection of the ascending aorta: evolution of reactive histologic changes","volume":"37","author":"Xu","year":"2013","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.lfs.2026.124443_bb0230","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1177\/0267659115590625","article-title":"Neutrophil to lymphocyte ratio: a novel marker for predicting hospital mortality of patients with acute type a aortic dissection","volume":"32","author":"Kalkan","year":"2015","journal-title":"Perfusion"},{"key":"10.1016\/j.lfs.2026.124443_bb0235","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0228954","article-title":"Factors related to white blood cell elevation in acute type A aortic dissection","volume":"15","author":"Suzuki","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2026.124443_bb0240","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.21037\/jtd.2018.05.93","article-title":"Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice","volume":"10","author":"Lu","year":"2018","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.lfs.2026.124443_bb0245","article-title":"Hydrogen protects lung from hypoxia\/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses","volume":"8","author":"Chen","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2026.124443_bb0250","doi-asserted-by":"crossref","first-page":"12130","DOI":"10.1038\/s41598-020-68930-2","article-title":"Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial","volume":"10","author":"Sim","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2026.124443_bb0255","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s13273-020-00074-w","article-title":"Molecular hydrogen protects against oxidative stress-induced RAW 264.7 macrophage cells through the activation of Nrf2 and inhibition of MAPK signaling pathway","volume":"16","author":"Begum","year":"2020","journal-title":"Mol. Cell. Toxicol."},{"key":"10.1016\/j.lfs.2026.124443_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116802","article-title":"Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease","volume":"176","author":"Zheng","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.lfs.2026.124443_bb0265","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2024.1410477","article-title":"The role of oxidative stress in aortic dissection: a potential therapeutic target","volume":"11","author":"Xu","year":"2024","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.lfs.2026.124443_bb0270","article-title":"A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs)","volume":"8","author":"Qi","year":"2020","journal-title":"Phys. Rep."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320526002523?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320526002523?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T08:17:47Z","timestamp":1784708267000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320526002523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":54,"alternative-id":["S0024320526002523"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2026.124443","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhalation of hydrogen gas reduces exacerbations of acute aortic dissection in mice","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2026.124443","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"124443"}}