{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:46:33Z","timestamp":1759963593784},"reference-count":61,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T00:00:00Z","timestamp":1243814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["La Presse M\u00e9dicale"],"published-print":{"date-parts":[[2009,6]]},"DOI":"10.1016\/j.lpm.2008.08.017","type":"journal-article","created":{"date-parts":[[2009,5,29]],"date-time":"2009-05-29T17:27:36Z","timestamp":1243618056000},"page":"911-926","source":"Crossref","is-referenced-by-count":10,"title":["Dyspn\u00e9e \u00e0 l\u2019effort chez le patient atteint de scl\u00e9rodermie syst\u00e9mique\u00a0: du sympt\u00f4me au diagnostic \u00e9tiologique"],"prefix":"10.1016","volume":"38","author":[{"given":"Eric","family":"Hachulla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Fran\u00e7ois","family":"Bervar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Launay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Lamblin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Mouthon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"De Groote","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Tillie-Leblond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Humbert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.lpm.2008.08.017_bib1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1164\/ajrccm.159.1.ats898","article-title":"Dyspnea: Mechanisms, assessment, and management: A consensus statement","volume":"159","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib2","first-page":"1529","article-title":"Evaluation of chronic dyspnea","volume":"71","author":"Karnani","year":"2005","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.lpm.2008.08.017_bib3","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1183\/09031936.05.00059404","article-title":"Understanding dyspnoea by its language","volume":"25","author":"Scano","year":"2005","journal-title":"Eur Respir J"},{"key":"10.1016\/j.lpm.2008.08.017_bib4","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1136\/bmj.2.6132.241","article-title":"Dyspnoea, disability, and distance walked: comparison of estimates of exercise performance in respiratory disease","volume":"2","author":"McGavin","year":"1978","journal-title":"Br Med J"},{"key":"10.1016\/j.lpm.2008.08.017_bib5","first-page":"822","article-title":"Dyspnea and pulmonary function tests","volume":"92","author":"Leiner","year":"1965","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.lpm.2008.08.017_bib6","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1002\/art.20787","article-title":"Correlation of the degree of dyspnea with health-related quality of life, functional abilities, and diffusing capacity for carbon monoxide in patients with systemic sclerosis and active alveolitis: results from the Scleroderma Lung Study","volume":"52","author":"Khanna","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lpm.2008.08.017_bib7","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1378\/chest.85.6.751","article-title":"The measurement of dyspnea. Contents, interobserver agreement, and physiologic correlates of two new clinical indexes","volume":"85","author":"Mahler","year":"1984","journal-title":"Chest"},{"key":"10.1016\/j.lpm.2008.08.017_bib8","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/thx.54.7.581","article-title":"Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease","volume":"54","author":"Bestall","year":"1999","journal-title":"Thorax"},{"key":"10.1016\/j.lpm.2008.08.017_bib9","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1159\/000089656","article-title":"Functional predictors of exertional dyspnea, 6-min walking distance and HRCT fibrosis score in idiopathic pulmonary fibrosis","volume":"73","author":"Mura","year":"2006","journal-title":"Respiration"},{"key":"10.1016\/j.lpm.2008.08.017_bib10","unstructured":"Borg G. Simple rating methods for estimation of perceived exertion. Wenner-Gren Center International Symposium Series 1976; 28:39\u201347."},{"key":"10.1016\/j.lpm.2008.08.017_bib11","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1378\/chest.06-2674","article-title":"Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines","volume":"131","author":"Badesch","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.lpm.2008.08.017_bib12","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S1388-9842(01)00206-9","article-title":"An evaluation of symptom classification systems used for the assessment of patients with heart failure in France","volume":"3","author":"Gibelin","year":"2001","journal-title":"Eur J Heart Fail"},{"key":"10.1016\/j.lpm.2008.08.017_bib13","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1164\/ajrccm.166.1.at1102","article-title":"ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories","volume":"166","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib14","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1164\/rccm.200702-326OC","article-title":"Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease","volume":"176","author":"Tashkin","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib15","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1081\/COPD-200050666","article-title":"The MCID of the transition dyspnea index is a total score of one unit","volume":"2","author":"Mahler","year":"2005","journal-title":"Copd"},{"key":"10.1016\/j.lpm.2008.08.017_bib16","doi-asserted-by":"crossref","first-page":"3792","DOI":"10.1002\/art.21433","article-title":"Early detection of pulmonary arterial hypertension in systemic sclerosis. A French nationwide prospective multicenter study","volume":"52","author":"Hachulla","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lpm.2008.08.017_bib17","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0002-9149(99)00877-2","article-title":"Prognostic usefulness of the tricuspid annular plane systolic excursion in patients with congestive heart failure secondary to idiopathic or ischemic dilated cardiomyopathy","volume":"85","author":"Ghio","year":"2000","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.lpm.2008.08.017_bib18","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1053\/euhj.2000.2296","article-title":"Pulsed Doppler tissue imaging of the velocity of tricuspid annular systolic motion\u00a0; a new, rapid, and non-invasive method of evaluating right ventricular systolic function","volume":"22","author":"Meluz\u00edn","year":"2001","journal-title":"Eur Heart J"},{"key":"10.1016\/j.lpm.2008.08.017_bib19","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0735-1097(97)00144-7","article-title":"Evaluation of diastolic filling of left ventricle in health and disease: Doppler echocardiography is the clinician's Rosetta Stone","volume":"30","author":"Nishimura","year":"1997","journal-title":"J Am Coll Cardiol"},{"issue":"3 Pt 2","key":"10.1016\/j.lpm.2008.08.017_bib20","doi-asserted-by":"crossref","first-page":"S83","DOI":"10.1016\/S0761-8425(07)91120-1","article-title":"Strat\u00e9gies d\u2019interpr\u00e9tation des explorations fonctionnelles respiratoires","volume":"24","author":"Pellegrino","year":"2007","journal-title":"Rev Mal Respir"},{"key":"10.1016\/j.lpm.2008.08.017_bib21","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1002\/art.1780370903","article-title":"Severe restrictive lung disease in systemic sclerosis","volume":"37","author":"Steen","year":"1994","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lpm.2008.08.017_bib22","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1093\/rheumatology\/keh067","article-title":"Echocardiography and pulmonary function as screening tests for pulmonary arterial hypertension in systemic sclerosis","volume":"43","author":"Mukerjee","year":"2004","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.lpm.2008.08.017_bib23","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1002\/art.10775","article-title":"Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement","volume":"48","author":"Steen","year":"2003","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lpm.2008.08.017_bib24","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1378\/chest.129.2.378","article-title":"Diffusing capacity for nitric oxide and carbon monoxide in patients with diffuse parenchymal lung disease and pulmonary arterial hypertension","volume":"129","author":"van der Lee","year":"2006","journal-title":"Chest."},{"key":"10.1016\/j.lpm.2008.08.017_bib25","doi-asserted-by":"crossref","first-page":"1S154","DOI":"10.1016\/S0761-8425(07)72889-9","article-title":"Int\u00e9r\u00eat du volume capillaire pulmonaire par la technique de la double diffusion CO-NO dans la scl\u00e9rodermie syst\u00e9mique","volume":"24","author":"Perez","year":"2007","journal-title":"Rev Mal Respir"},{"key":"10.1016\/j.lpm.2008.08.017_bib26","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1164\/ajrccm.161.2.ats3-00","article-title":"Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American thoracic society (ATS), and the European Respiratory Society (ERS)","volume":"161","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib27","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1378\/chest.06-0630","article-title":"Six-minute walk test for the evaluation of pulmonary disease severity in scleroderma patients","volume":"131","author":"Villalba","year":"2007","journal-title":"Chest"},{"key":"10.1016\/j.lpm.2008.08.017_bib28","first-page":"1194","article-title":"Systemic sclerosis - continuing progress in developing clinical measures of response","volume":"34","author":"Furst","year":"2007","journal-title":"J Rheumatol"},{"key":"10.1016\/j.lpm.2008.08.017_bib29","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1136\/ard.2006.054866","article-title":"Submaximal exercise testing in the assessment of interstitial lung disease secondary to systemic sclerosis: reproducibility and correlations of the 6-min walk test","volume":"66","author":"Buch","year":"2007","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.lpm.2008.08.017_bib30","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1164\/ajrccm.161.2.9906015","article-title":"Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing","volume":"161","author":"Miyamoto","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib31","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1164\/ajrccm.155.4.9105067","article-title":"Interpreting small differences in functional status: the Six Minute Walk test in chronic lung disease patients","volume":"155","author":"Redelmeier","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib32","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/S0735-1097(02)02012-0","article-title":"Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival","volume":"40","author":"Sitbon","year":"2002","journal-title":"J Am Coll Cardiol"},{"issue":"3 Pt 2","key":"10.1016\/j.lpm.2008.08.017_bib33","article-title":"M\u00e9thodologie et Pratique de l\u2019Exploration Fonctionnelle \u00e0 l\u2019eXercice (EFX)","volume":"24","author":"Aguilaniu","year":"2007","journal-title":"Rev Mal Respir"},{"key":"10.1016\/j.lpm.2008.08.017_bib34","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1378\/chest.110.6.1520","article-title":"Cardiorespiratory responses to incremental exercise in patients with systemic sclerosis","volume":"110","author":"Schwaiblmair","year":"1996","journal-title":"Chest"},{"key":"10.1016\/j.lpm.2008.08.017_bib35","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0002-9343(93)90311-C","article-title":"Failure of the circulatory system limits exercise performance in patients with systemic sclerosis","volume":"95","author":"Sudduth","year":"1993","journal-title":"Am J Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib36","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1161\/CIRCULATIONAHA.104.488486","article-title":"Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension","volume":"14","author":"Sitbon","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.lpm.2008.08.017_bib37","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/art.1780390226","article-title":"Gastric antral vascular ectasia (watermelon stomach) in patients with systemic sclerosis","volume":"39","author":"Watson","year":"1996","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lpm.2008.08.017_bib38","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S0889-857X(05)70305-7","article-title":"Scleroderma renal crisis","volume":"22","author":"Steen","year":"1996","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1016\/j.lpm.2008.08.017_bib39","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1002\/anr.1780320911","article-title":"Normotensive renal failure in systemic sclerosis","volume":"32","author":"Helfrich","year":"1989","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lpm.2008.08.017_bib40","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1136\/ard.2006.066068","article-title":"Changes in causes of death in systemic sclerosis, 1972\u20132002","volume":"66","author":"Steen","year":"2007","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.lpm.2008.08.017_bib41","doi-asserted-by":"crossref","unstructured":"American thoracic society\/european respiratory society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001. Am J Respir Crit Care Med 2002; 165:277\u2013304.","DOI":"10.1164\/ajrccm.165.2.ats01"},{"key":"10.1016\/j.lpm.2008.08.017_bib42","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1164\/ajrccm.149.6.8004317","article-title":"Fibrosing alveolitis associated with systemic sclerosis has a better prognosis than lone cryptogenic fibrosing alveolitis","volume":"149","author":"Wells","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib43","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/00005792-200203000-00005","article-title":"Predicting mortality in systemic sclerosis: analysis of a cohort of 309 French Canadian patients with emphasis on features at diagnosis as predictive factors for survival","volume":"81","author":"Scussel-Lonzetti","year":"2002","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.lpm.2008.08.017_bib44","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1002\/1529-0131(200011)43:11<2437::AID-ANR10>3.0.CO;2-U","article-title":"Severe organ involvement in systemic sclerosis with diffuse scleroderma","volume":"43","author":"Steen","year":"2000","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lpm.2008.08.017_bib45","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/art.1780230510","article-title":"Preliminary criteria for the classification of systemic sclerosis (scleroderma)","volume":"23","author":"Masi","year":"1980","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lpm.2008.08.017_bib46","first-page":"167","article-title":"Pathog\u00e9nie de la scl\u00e9rodermie\u00a0: aspects immunologiques","volume":"153","author":"Mouthon","year":"2002","journal-title":"Ann Med Int"},{"key":"10.1016\/j.lpm.2008.08.017_bib47","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1148\/radiol.2322031223","article-title":"CT features of lung disease in patients with systemic sclerosis: comparison with idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia","volume":"232","author":"Desai","year":"2004","journal-title":"Radiology"},{"key":"10.1016\/j.lpm.2008.08.017_bib48","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1164\/rccm.2106012","article-title":"Histopathologic subsets of fibrosing alveolitis in patients with systemic sclerosis and their relationship to outcome","volume":"165","author":"Bouros","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib49","doi-asserted-by":"crossref","first-page":"S151","DOI":"10.1148\/radiographics.22.suppl_1.g02oc04s151","article-title":"Interstitial lung diseases associated with collagen vascular diseases: radiologic and histopathologic findings","volume":"22","author":"Kim","year":"2002","journal-title":"Radiographics"},{"key":"10.1016\/j.lpm.2008.08.017_bib50","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1136\/ard.62.2.97","article-title":"Predictors of end stage lung disease in systemic sclerosis","volume":"62","author":"Steen","year":"2003","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.lpm.2008.08.017_bib51","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1136\/ard.62.11.1088","article-title":"Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach","volume":"62","author":"Mukerjee","year":"2003","journal-title":"Ann Rheum Dis"},{"issue":"12 Suppl. S","key":"10.1016\/j.lpm.2008.08.017_bib52","doi-asserted-by":"crossref","first-page":"5S","DOI":"10.1016\/j.jacc.2004.02.037","article-title":"Clinical classification of pulmonary hypertension","volume":"43","author":"Simonneau","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.lpm.2008.08.017_bib53","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1164\/rccm.200510-1668OC","article-title":"Pulmonary arterial hypertension in France: results from a National Registry","volume":"173","author":"Humbert","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2008.08.017_bib54","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2214\/ajr.183.1.1830065","article-title":"Pulmonary hypertension: CT of the chest in pulmonary venoocclusive disease","volume":"183","author":"Resten","year":"2004","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.lpm.2008.08.017_bib55","first-page":"2347","article-title":"Pulmonary veno-occlusive disease and scleroderma associated pulmonary hypertension","volume":"33","author":"Johnson","year":"2006","journal-title":"J Rheumatol"},{"key":"10.1016\/j.lpm.2008.08.017_bib56","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1183\/09031936.06.00054105","article-title":"Occult alveolar haemorrhage in pulmonary veno-occlusive disease","volume":"27","author":"Rabiller","year":"2006","journal-title":"Eur Respir J"},{"key":"10.1016\/j.lpm.2008.08.017_bib57","first-page":"1901","article-title":"Atteintes cardiaques et pulmonaires scl\u00e9rodermiques","volume":"52","author":"Launay","year":"2002","journal-title":"Rev Prat"},{"key":"10.1016\/j.lpm.2008.08.017_bib58","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/rheumatology\/34.7.684","article-title":"Phrenicus palsy in progressive systemic sclerosis","volume":"34","author":"Birk","year":"1995","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.lpm.2008.08.017_bib59","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1136\/thx.36.3.219","article-title":"Progressive generalized scleroderma: respiratory failure from primary chest wall involvement","volume":"39","author":"Russel","year":"1981","journal-title":"Thorax"},{"key":"10.1016\/j.lpm.2008.08.017_bib60","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1136\/ard.62.8.728","article-title":"Risk of cancer in patients with scleroderma: a population based cohort study","volume":"62","author":"Hill","year":"2003","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.lpm.2008.08.017_bib61","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1002\/art.21225","article-title":"Risk of malignancy in scleroderma: a population-based cohort study","volume":"52","author":"Chatterjee","year":"2005","journal-title":"Arthritis Rheum"}],"container-title":["La Presse M\u00e9dicale"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0755498208007239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0755498208007239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T12:48:02Z","timestamp":1558356482000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0755498208007239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6]]},"references-count":61,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,6]]}},"alternative-id":["S0755498208007239"],"URL":"https:\/\/doi.org\/10.1016\/j.lpm.2008.08.017","relation":{},"ISSN":["0755-4982"],"issn-type":[{"value":"0755-4982","type":"print"}],"subject":[],"published":{"date-parts":[[2009,6]]}}}