{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T01:55:35Z","timestamp":1773798935216,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["La Presse M\u00e9dicale"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.lpm.2016.09.013","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T03:02:04Z","timestamp":1484103724000},"page":"85-95","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Histiocytose langerhansienne de l\u2019enfant"],"prefix":"10.1016","volume":"46","author":[{"given":"Jean","family":"Donadieu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9bastien","family":"H\u00e9ritier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.lpm.2016.09.013_bib0180","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1182\/blood-2010-04-279083","article-title":"Recurrent BRAF mutations in Langerhans cell histiocytosis","volume":"116","author":"Badalian-Very","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.lpm.2016.09.013_bib0185","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1517\/14656566.2012.688028","article-title":"Medical management of Langerhans cell histiocytosis from diagnosis to treatment","volume":"13","author":"Donadieu","year":"2012","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.lpm.2016.09.013_bib0190","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/pbc.21498","article-title":"Descriptive epidemiology of childhood Langerhans cell histiocytosis in France, 2000\u20132004","volume":"51","author":"Guyot-Goubin","year":"2008","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0195","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.humpath.2004.03.017","article-title":"Expression of Epstein-Barr virus in Langerhans\u2019 cell histiocytosis","volume":"35","author":"Shimakage","year":"2004","journal-title":"Hum Pathol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0200","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/1523-1747.ep12371669","article-title":"Human herpesvirus 6\u00a0is present in lesions of Langerhans cell histiocytosis","volume":"101","author":"Leahy","year":"1993","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0205","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s004280050313","article-title":"Human cytomegalovirus infection in foci of Langerhans cell histiocytosis","volume":"434","author":"Kawakubo","year":"1999","journal-title":"Virchows Arch"},{"key":"10.1016\/j.lpm.2016.09.013_bib0210","doi-asserted-by":"crossref","first-page":"e3262","DOI":"10.1371\/journal.pone.0003262","article-title":"Herpesvirus infection in patients with Langerhans cell histiocytosis: a case-controlled sero-epidemiological study, and in situ analysis","volume":"3","author":"Jeziorski","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.lpm.2016.09.013_bib0215","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1749-6632.1986.tb18541.x","article-title":"Smoking and interstitial lung disease. The effect of cigarette smoking on the incidence of pulmonary histiocytosis X and sarcoidosis","volume":"465","author":"Hance","year":"1986","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.lpm.2016.09.013_bib0220","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1002\/1097-0142(19951215)76:12<2471::AID-CNCR2820761211>3.0.CO;2-Z","article-title":"Langerhans\u2019 cell histiocytosis (histiocytosis X) of bone. A clinicopathologic analysis of 263\u00a0pediatric and adult cases","volume":"76","author":"Kilpatrick","year":"1995","journal-title":"Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0225","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/00043426-199602000-00010","article-title":"Detection of bone lesions in Langerhans cell histiocytosis: complementary roles of scintigraphy and conventional radiography","volume":"18","author":"Dogan","year":"1996","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0230","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/pbc.21782","article-title":"Comparison of FDG-PET scans to conventional radiography and bone scans in management of Langerhans cell histiocytosis","volume":"52","author":"Phillips","year":"2009","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0235","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1007\/s00247-006-0246-7","article-title":"Whole-body MRI of Langerhans cell histiocytosis: comparison with radiography and bone scintigraphy","volume":"36","author":"Goo","year":"2006","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0240","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/pbc.24367","article-title":"Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work-up, and treatment for patients till the age of 18\u00a0years","volume":"60","author":"Haupt","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0245","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1365-4362.1986.tb00867.x","article-title":"Congenital self-healing reticulohistiocytosis (Hashimoto-Pritzker type)","volume":"25","author":"Hashimoto","year":"1986","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0250","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jpeds.2003.12.030","article-title":"Endocrine involvement in pediatric-onset Langerhans\u2019 cell histiocytosis: a population-based study","volume":"144","author":"Donadieu","year":"2004","journal-title":"J Pediatr"},{"key":"10.1016\/j.lpm.2016.09.013_bib0255","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/pbc.20425","article-title":"Risk factors for diabetes insipidus in Langerhans cell histiocytosis","volume":"46","author":"Grois","year":"2006","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0260","series-title":"Histiocytic disorders in children and adults","article-title":"Late effects of Langerhans cell histiocytosis and the association of LCH with malignancy","author":"Haupt","year":"2005"},{"key":"10.1016\/j.lpm.2016.09.013_bib0265","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1210\/jc.2003-030907","article-title":"Incidence of growth hormone deficiency in pediatric-onset Langerhans cell histiocytosis: efficacy and safety of growth hormone treatment","volume":"89","author":"Donadieu","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.lpm.2016.09.013_bib0270","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1002\/pbc.20021","article-title":"Permanent consequences in Langerhans cell histiocytosis patients: a pilot study from the Histiocyte Society-Late Effects Study Group","volume":"42","author":"Haupt","year":"2004","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0275","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1164\/rccm.2201050","article-title":"Three-dimensional characterization of pathologic lesions in pulmonary Langerhans cell histiocytosis","volume":"166","author":"Kambouchner","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.lpm.2016.09.013_bib0280","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/pbc.20593","article-title":"Isolated pulmonary Langerhans cell histiocytosis presenting with recurrent pneumothorax","volume":"48","author":"Braier","year":"2007","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0285","series-title":"Histiocytic disorders of children and adults","first-page":"187","article-title":"Adult lung histiocytosis","author":"Tazi","year":"2005"},{"key":"10.1016\/j.lpm.2016.09.013_bib0290","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1002\/mpo.1306","article-title":"Cholestasis, sclerosing cholangitis, and liver transplantation in Langerhans cell Histiocytosis","volume":"38","author":"Braier","year":"2002","journal-title":"Med Pediatr Oncol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0295","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1002\/pbc.24603","article-title":"Thymus and mediastinal node involvement in childhood Langerhans cell histiocytosis: long-term follow-up from the French national cohort","volume":"60","author":"Ducassou","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0300","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/S0022-3476(96)70027-6","article-title":"Digestive tract involvement in Langerhans cell histiocytosis. The French Langerhans Cell Histiocytosis Study Group","volume":"129","author":"Geissmann","year":"1996","journal-title":"J Pediatr"},{"key":"10.1016\/j.lpm.2016.09.013_bib0305","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1136\/adc.75.1.17","article-title":"A multicentre retrospective survey of Langerhans\u2019 cell histiocytosis: 348\u00a0cases observed between 1983\u00a0and 1993","volume":"75","author":"The French Langerhans\u2019 Cell Histiocytosis Study Group","year":"1996","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.lpm.2016.09.013_bib0310","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1136\/adc.82.6.483","article-title":"Long-term follow-up of topical mustine treatment for cutaneous Langerhans cell histiocytosis","volume":"82","author":"Hoeger","year":"2000","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.lpm.2016.09.013_bib0315","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/mpo.10166","article-title":"Response to initial treatment of multisystem Langerhans cell histiocytosis: an important prognostic indicator","volume":"39","author":"Minkov","year":"2002","journal-title":"Med Pediatr Oncol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0320","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1002\/pbc.22229","article-title":"2\u2019-Chlorodeoxyadenosine (2\u00a0Cda) as salvage therapy for Langerhans cell histiocytosis (LCH). Results of the LCH-S-98\u00a0protocol of the Histiocyte Society","volume":"53","author":"Weitzman","year":"2009","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.lpm.2016.09.013_bib0325","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/sj.bmt.1705015","article-title":"Improved outcome of treatment-resistant high-risk Langerhans cell histiocytosis after allogeneic stem cell transplantation with reduced-intensity conditioning","volume":"36","author":"Steiner","year":"2005","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.lpm.2016.09.013_bib0330","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1182\/blood-2015-03-635151","article-title":"Cladribine and cytarabine in refractory multisystem Langerhans cell histiocytosis: results of an international phase 2\u00a0study","volume":"126","author":"Donadieu","year":"2015","journal-title":"Blood"},{"key":"10.1016\/j.lpm.2016.09.013_bib0335","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1200\/JCO.2014.57.1950","article-title":"Reproducible and sustained efficacy of targeted therapy with vemurafenib in patients with BRAFV600E-mutated Erdheim-Chester disease","volume":"33","author":"Haroche","year":"2015","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0340","doi-asserted-by":"crossref","DOI":"10.1001\/jamaoncol.2015.0736","article-title":"Vemurafenib use in an infant for high-risk Langerhans cell histiocytosis","author":"Heritier","year":"2015","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.lpm.2016.09.013_bib0345","doi-asserted-by":"crossref","DOI":"10.1183\/09031936.00210711","article-title":"Serial CT and lung function testing in pulmonary Langerhans cell histiocytosis","author":"Tazi","year":"2012","journal-title":"Eur Respir J"},{"key":"10.1016\/j.lpm.2016.09.013_bib0175","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1002\/pbc.20160","article-title":"A new clinical score for disease activity in Langerhans cell histiocytosis","volume":"43","author":"Donadieu","year":"2004","journal-title":"Pediatr Blood Cancer"}],"container-title":["La Presse M\u00e9dicale"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0755498216302755?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0755498216302755?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T05:20:18Z","timestamp":1536124818000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0755498216302755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S0755498216302755"],"URL":"https:\/\/doi.org\/10.1016\/j.lpm.2016.09.013","relation":{},"ISSN":["0755-4982"],"issn-type":[{"value":"0755-4982","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Histiocytose langerhansienne de l\u2019enfant","name":"articletitle","label":"Article Title"},{"value":"La Presse M\u00e9dicale","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lpm.2016.09.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}