{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T01:11:59Z","timestamp":1761959519519,"version":"build-2065373602"},"reference-count":6,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":196,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Leukemia Research Reports"],"published-print":{"date-parts":[[2013]]},"DOI":"10.1016\/j.lrr.2012.10.001","type":"journal-article","created":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T10:59:32Z","timestamp":1357901972000},"page":"9-11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Durable second complete remissions with oral melphalan in hypocellular Acute Myeloid Leukemia and Refractory Anemia with Excess Blast with normal karyotype relapsing after intensive chemotherapy"],"prefix":"10.1016","volume":"2","author":[{"given":"Annika M.","family":"Whittle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvia","family":"Feyler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David T.","family":"Bowen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.lrr.2012.10.001_bib1","first-page":"2312","article-title":"Low-dose melphalan is an effective and low-cost treatment for high- risk myelodysplastic syndromes with hypoplastic marrow","volume":"88","author":"Omoto","year":"1996","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.lrr.2012.10.001_bib2","first-page":"67","article-title":"Remission induction in elderly acute myeloid leukemia by low-dose melphalan","volume":"41","author":"Gologan","year":"2003","journal-title":"Romanian Journal of Internal Medicine"},{"issue":"2","key":"10.1016\/j.lrr.2012.10.001_bib3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1163\/156855902320388023","article-title":"Low dose melphalan is a treatment option in elderly patients with high risk myelodysplastic syndrome or secondary acute myeloblastic leukaemia","volume":"32","author":"Anargyrou","year":"2002","journal-title":"Haematologia (Budap)"},{"issue":"1","key":"10.1016\/j.lrr.2012.10.001_bib4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1046\/j.1365-2141.2000.01825.x","article-title":"Low-dose melphalan induces favourable responses in elderly patients with high-risk myelodysplastic syndromes or secondary acute myeloid leukaemia","volume":"108","author":"Denzlinger","year":"2000","journal-title":"British Journal of Haematology"},{"issue":"5","key":"10.1016\/j.lrr.2012.10.001_bib5","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1038\/sj.leu.2401762","article-title":"Low-dose melphalan in elderly acute myeloid leukaemia: complete remissions but resistant relapse with therapy-related karyotypes","volume":"14","author":"Kerr","year":"2000","journal-title":"Leukemia"},{"issue":"3","key":"10.1016\/j.lrr.2012.10.001_bib6","first-page":"172","article-title":"Efficacy and toxicity of low-dose melphalan in myelodysplastic syndromes and acute myeloid leukemia with multilineage dysplasia","volume":"50","author":"Robak","year":"2003","journal-title":"Neoplasma"}],"container-title":["Leukemia Research Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213048912000064?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213048912000064?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T01:07:06Z","timestamp":1761959226000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213048912000064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013]]}},"alternative-id":["S2213048912000064"],"URL":"https:\/\/doi.org\/10.1016\/j.lrr.2012.10.001","relation":{},"ISSN":["2213-0489"],"issn-type":[{"type":"print","value":"2213-0489"}],"subject":[],"published":{"date-parts":[[2013]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Durable second complete remissions with oral melphalan in hypocellular Acute Myeloid Leukemia and Refractory Anemia with Excess Blast with normal karyotype relapsing after intensive chemotherapy","name":"articletitle","label":"Article Title"},{"value":"Leukemia Research Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lrr.2012.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}