{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:22:26Z","timestamp":1789906946964,"version":"4.0.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Lung Cancer"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.lungcan.2011.09.015","type":"journal-article","created":{"date-parts":[[2011,10,19]],"date-time":"2011-10-19T22:22:57Z","timestamp":1319062977000},"page":"72-77","source":"Crossref","is-referenced-by-count":26,"title":["Omitting elective nodal irradiation during thoracic irradiation in limited-stage small cell lung cancer \u2013 Evidence from a phase II trial"],"prefix":"10.1016","volume":"76","clinical-trial-number":[{"clinical-trial-number":"nct00433563","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Rovel","family":"Colaco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Sheikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Lorigan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"Blackhall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Hulse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Califano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Ashcroft","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Thatcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinne","family":"Faivre-Finn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lungcan.2011.09.015_bib0005","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0169-5002(89)90156-6","article-title":"Staging and prognostic factors in small cell lung cancer: a consensus report","volume":"5","author":"Stahel","year":"1989","journal-title":"Lung Cancer"},{"issue":"9","key":"10.1016\/j.lungcan.2011.09.015_bib0010","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1097\/JTO.0b013e3181b27799","article-title":"The IASLC Lung Cancer Staging Project: proposals regarding the relevance of TNM in the pathologic staging of small cell lung cancer in the forthcoming (seventh) edition of the TNM classification for lung cancer","volume":"4","author":"Valli\u00e8res","year":"2009","journal-title":"J Thorac Oncol"},{"issue":"3","key":"10.1016\/j.lungcan.2011.09.015_bib0015","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.lungcan.2008.06.013","article-title":"Radiotherapy for small-cell lung cancer \u2013 where are we heading?","volume":"63","author":"Bayman","year":"2009","journal-title":"Lung Cancer"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0020","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3816\/CLC.2005.n.018","article-title":"Thoracic radiation therapy for limited-stage small-cell lung cancer: unanswered questions","volume":"7","author":"Faivre-Finn","year":"2005","journal-title":"Clin Lung Cancer"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0025","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/annonc\/mdj094","article-title":"Systematic review and meta-analysis of randomised, controlled trials of the timing of chest radiotherapy in patients with limited-stage, small-cell lung cancer","volume":"17","author":"De Ruysscher","year":"2006","journal-title":"Ann Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0030","doi-asserted-by":"crossref","first-page":"4837","DOI":"10.1200\/JCO.2004.01.178","article-title":"Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer","volume":"22","author":"Fried","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0035","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1634\/theoncologist.9-6-665","article-title":"A meta-analysis of the timing of chest irradiation in the combined modality treatment of limited-stage small cell lung cancer","volume":"9","author":"Huncharek","year":"2004","journal-title":"Oncologist"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0040","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1056\/NEJM199901283400403","article-title":"Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide","volume":"340","author":"Turrisi","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0045","doi-asserted-by":"crossref","first-page":"7583","DOI":"10.1200\/jco.2008.26.15_suppl.7583","article-title":"Feasibility and toxicity report from a phase II study of accelerated twice-daily (BDRT) versus high dose once-daily thoracic radiotherapy (ODRT) with concurrent chemotherapy for limited stage small cell lung cancer (LS-SCLC)","volume":"26","author":"Faivre-Finn","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0050","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1200\/JCO.1999.17.9.2681","article-title":"Phase III comparison of twice-daily split-course irradiation versus once-daily irradiation for patients with limited stage small-cell lung carcinoma","volume":"17","author":"Bonner","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0055","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1200\/JCO.1997.15.3.893","article-title":"Initial versus delayed accelerated hyperfractionated radiation therapy and concurrent chemotherapy in limited small-cell lung cancer: a randomized study","volume":"15","author":"Jeremic","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0060","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.1200\/JCO.2002.12.071","article-title":"Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer: results of the Japan Clinical Oncology Group Study 9104","volume":"20","author":"Takada","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0065","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.radonc.2006.07.029","article-title":"Omission of elective node irradiation on basis of CT-scans in patients with limited disease small cell lung cancer: a phase II trial","volume":"80","author":"De Ruysscher","year":"2006","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0070","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1038\/sj.bjc.6602979","article-title":"Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: a Dutch multicenter phase II study","volume":"94","author":"Baas","year":"2006","journal-title":"Br J Cancer"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0075","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.ijrobp.2009.04.075","article-title":"Selective nodal irradiation on basis of (18)FDG-PET scans in limited-disease small-cell lung cancer: a Prospective Study","volume":"77","author":"van Loon","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0080","unstructured":"Website: http:\/\/ctep.cancer.gov\/protocoldevelopment\/electronic_applications\/docs\/ctcaev3.pdf."},{"key":"10.1016\/j.lungcan.2011.09.015_bib0085","first-page":"4","article-title":"Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in nonsmall cell lung cancer","volume":"30","author":"Sulman","year":"2009","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0090","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.ijrobp.2008.03.075","article-title":"Report from the International Atomic Energy Agency (IAEA) consultants\u2019 meeting on elective nodal irradiation in lung cancer: small-cell lung cancer (SCLC)","volume":"72","author":"Videtic","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0095","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0360-3016(01)01482-1","article-title":"Elective nodal irradiation in the treatment of non-small-cell lung cancer with three-dimensional conformal radiation therapy","volume":"50","author":"Rosenzweig","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0100","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0360-3016(02)03028-6","article-title":"Can elective nodal irradiation be omitted in stage III non-small-cell lung cancer? Analysis of recurrences in a phase II study of induction chemotherapy and involved-field radiotherapy","volume":"54","author":"Senan","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0105","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/sj.bjc.6603861","article-title":"Reply patterns of nodal recurrence after omission of elective nodal irradiation for limited-stage small cell lung cancer","volume":"97","author":"Belderbos","year":"2007","journal-title":"Br J Cancer"},{"issue":"1","key":"10.1016\/j.lungcan.2011.09.015_bib0110","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.radonc.2008.02.019","article-title":"18FDG-PET based radiation planning of mediastinal lymph nodes in limited disease small cell lung cancer changes radiotherapy fields: a planning study","volume":"87","author":"van Loon","year":"2008","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0115","article-title":"Positron emission tomography\/computer tomography guided intensity modulated radiotherapy for limited-stage small cell lung cancer","author":"Shirvani","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.lungcan.2011.09.015_bib0120","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.clon.2010.05.008","article-title":"Improving survival with thoracic radiotherapy in patients with small cell lunch cancer. The CONVERT and the REST trails","volume":"22","author":"Faivre-Finn","year":"2010","journal-title":"Clin Oncol (R Coll Radiol)"}],"container-title":["Lung Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169500211004843?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169500211004843?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T04:35:43Z","timestamp":1560832543000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169500211004843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0169500211004843"],"URL":"https:\/\/doi.org\/10.1016\/j.lungcan.2011.09.015","relation":{},"ISSN":["0169-5002"],"issn-type":[{"value":"0169-5002","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}