{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:46:07Z","timestamp":1784133967591,"version":"3.55.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["lungcancerjournal.info","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Lung Cancer"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.lungcan.2014.07.007","type":"journal-article","created":{"date-parts":[[2014,7,17]],"date-time":"2014-07-17T03:15:34Z","timestamp":1405566934000},"page":"401-407","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Efficacy and safety of pemetrexed\/cisplatin versus gemcitabine\/cisplatin as first-line treatment in Chinese patients with advanced nonsquamous non-small cell lung cancer"],"prefix":"10.1016","volume":"85","clinical-trial-number":[{"clinical-trial-number":"nct00087711","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Yi-Long","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caicun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengzhao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shukui","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunzhong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangqun","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Barraclough","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haidong","family":"Chi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Orlando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lungcan.2014.07.007_bib0005","series-title":"GLOBOCAN 2012 v1.0, cancer incidence and mortality worldwide: IARC CancerBase no. 11 [Internet]","author":"Ferlay","year":"2013"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0010","first-page":"179","article-title":"Efficacy of pemetrexed as second-line therapy or beyond in patients with advanced non-small cell lung cancer","volume":"15","author":"Li","year":"2012","journal-title":"Chin J Lung Cancer"},{"issue":"Suppl 1","key":"10.1016\/j.lungcan.2014.07.007_bib0015","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1016\/S0169-5002(05)81555-7","article-title":"a new cytotoxic agent in the development for first-line non-small-cell lung cancer","volume":"50","author":"Scagliotti","year":"2005","journal-title":"Lung Cancer"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0020","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1200\/JCO.2007.15.0375","article-title":"Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer","volume":"26","author":"Scagliotti","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0025","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S1359-6349(07)71349-6","article-title":"Is pemetrexed more effective in patients with non-squamous histology? A retrospective analysis of a phase III trial of pemetrexed vs docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC) [abstract]","volume":"5","author":"Peterson","year":"2007","journal-title":"Eur J Cancer Suppl"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0030","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1634\/theoncologist.2008-0232","article-title":"The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies","volume":"14","author":"Scagliotti","year":"2009","journal-title":"Oncologist"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0035","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1016\/S0140-6736(09)61497-5","article-title":"Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study","volume":"374","author":"Ciuleanu","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0040","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1097\/JTO.0b013e3181d1273d","article-title":"Efficacy and safety of cisplatin\/pemetrexed versus cisplatin\/gemcitabine as first-line treatment in East Asian patients with advanced non-small cell lung cancer: results of an exploratory subgroup analysis of a phase III trial","volume":"5","author":"Yang","year":"2010","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0045","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1056\/NEJMoa0810699","article-title":"Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma","volume":"361","author":"Mok","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0050","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1016\/S0140-6736(08)61758-4","article-title":"Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial","volume":"372","author":"Kim","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0055","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1097\/JTO.0b013e3181e15d55","article-title":"Efficacy and safety of erlotinib in 1242 East\/South-East Asian patients with advanced non-small cell lung cancer","volume":"5","author":"Mok","year":"2010","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0060","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/JTO.0000000000000033","article-title":"A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology (PIONEER)","volume":"9","author":"Shi","year":"2014","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0065","doi-asserted-by":"crossref","first-page":"6251","DOI":"10.1200\/JCO.2009.23.5622","article-title":"American society of clinical oncology clinical practice guideline update on chemotherapy for stage IV non-small-cell lung cancer","volume":"27","author":"Azzoli","year":"2009","journal-title":"J Clin Oncol"},{"issue":"Supplement 5","key":"10.1016\/j.lungcan.2014.07.007_bib0070","doi-asserted-by":"crossref","first-page":"v116","DOI":"10.1093\/annonc\/mdq189","article-title":"Metastatic non-small-cell lung cancer: ESMO clinical practice guidelines for diagnosis, treatment and followup","volume":"21","author":"D\u2019Addario","year":"2010","journal-title":"Ann Oncol"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0075","series-title":"2010 Chinese Lung cancer clinical guideline","first-page":"52","year":"2010"},{"issue":"3","key":"10.1016\/j.lungcan.2014.07.007_bib0080","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S1470-2045(12)70063-3","volume":"13","author":"Paz-Ares","year":"2012","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.lungcan.2014.07.007_bib0085","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1097\/JTO.0b013e318226b5fa","article-title":"A randomized phase 3 trial comparing pemetrexed\/carboplatin and docetaxel\/carboplatin as first-line treatment for advanced, nonsquamous non-small cell lung cancer","volume":"6","author":"Rodrigues-Pereira","year":"2011","journal-title":"J Thorac Oncol"}],"container-title":["Lung Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169500214003079?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169500214003079?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T14:53:32Z","timestamp":1538405612000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169500214003079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S0169500214003079"],"URL":"https:\/\/doi.org\/10.1016\/j.lungcan.2014.07.007","relation":{},"ISSN":["0169-5002"],"issn-type":[{"value":"0169-5002","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy and safety of pemetrexed\/cisplatin versus gemcitabine\/cisplatin as first-line treatment in Chinese patients with advanced nonsquamous non-small cell lung cancer","name":"articletitle","label":"Article Title"},{"value":"Lung Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lungcan.2014.07.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}