{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:13:12Z","timestamp":1762866792400,"version":"3.40.5"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","lungcancerjournal.info","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Lung Cancer"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.lungcan.2016.01.006","type":"journal-article","created":{"date-parts":[[2016,1,12]],"date-time":"2016-01-12T15:29:57Z","timestamp":1452612597000},"page":"82-87","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Small-cell lung cancer in never-smokers: A case series"],"prefix":"10.1016","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3366-4295","authenticated-orcid":false,"given":"Ana","family":"Tavares e Castro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Clemente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Freitas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Cemlyn-Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.lungcan.2016.01.006_bib0005","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3322\/caac.20073","article-title":"Cancer statistics","volume":"60","author":"Jemal","year":"2010","journal-title":"CA Cancer J. Clin."},{"issue":"Suppl. 3","key":"10.1016\/j.lungcan.2016.01.006_bib0010","doi-asserted-by":"crossref","first-page":"234S","DOI":"10.1378\/chest.07-1378","article-title":"Treatment of non-small cell lung cancer stage I and stage II: ACCP evidence-based clinical practice guidelines (2nd edition)","volume":"132","author":"Scott","year":"2007","journal-title":"Chest"},{"issue":"28","key":"10.1016\/j.lungcan.2016.01.006_bib0015","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.1200\/JCO.2005.04.4859","article-title":"Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database","volume":"24","author":"Govindan","year":"2006","journal-title":"J. Clin. Oncol."},{"issue":"10","key":"10.1016\/j.lungcan.2016.01.006_bib0020","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/jnci\/djj187","article-title":"Lung cancer death rates in lifelong nonsmokers","volume":"98","author":"Thun","year":"2006","journal-title":"J. Natl. Cancer Inst."},{"issue":"Suppl. 1","key":"10.1016\/j.lungcan.2016.01.006_bib0025","doi-asserted-by":"crossref","first-page":"S69","DOI":"10.1111\/j.1539-6924.2012.01768.x","article-title":"Lung cancer in never smokers: epidemiology and risk prediction models","volume":"32","author":"McCarthy","year":"2012","journal-title":"Risk Anal."},{"issue":"10","key":"10.1016\/j.lungcan.2016.01.006_bib0030","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/nrc2190","article-title":"Lung cancer in never smokers\u2014a different disease","volume":"7","author":"Sun","year":"2007","journal-title":"Nat. Rev. Cancer"},{"issue":"1","key":"10.1016\/j.lungcan.2016.01.006_bib0035","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.cllc.2011.04.001","article-title":"Small-cell lung cancer in never-smokers: a case series with information on family history of cancer and environmental tobacco smoke","volume":"13","author":"Kurahara","year":"2012","journal-title":"Clin. Lung Cancer"},{"issue":"6","key":"10.1016\/j.lungcan.2016.01.006_bib0040","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1093\/annonc\/mdj114","article-title":"EGFR mutation in gefitinib-responsive small-cell lung cancer","volume":"17","author":"Okamoto","year":"2006","journal-title":"Ann. Oncol."},{"issue":"2","key":"10.1016\/j.lungcan.2016.01.006_bib0045","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1056\/NEJMc053610","article-title":"EGFR mutations in small-cell lung cancers in patients who have never smoked","volume":"355","author":"Zakowski","year":"2006","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.lungcan.2016.01.006_bib0050","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.3816\/CLC.2010.n.046","article-title":"Small-cell carcinoma with an epidermal growth factor receptor mutation in a never-smoker with gefitinib-responsive adenocarcinoma of the lung","author":"Alam","year":"2010","journal-title":"Clin. Lung Cancer"},{"issue":"1","key":"10.1016\/j.lungcan.2016.01.006_bib0055","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/JTO.0b013e3181f94abb","article-title":"Epidermal growth factor receptor mutations in small cell lung cancer: a brief report","volume":"6","author":"Shiao","year":"2011","journal-title":"J. Thorac. Oncol."},{"issue":"5","key":"10.1016\/j.lungcan.2016.01.006_bib0060","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1097\/JTO.0b013e3181d6e124","article-title":"Small cell lung cancer in never smokers: report of two cases","volume":"5","author":"Antony","year":"2010","journal-title":"J. Thorac. Oncol."},{"issue":"3","key":"10.1016\/j.lungcan.2016.01.006_bib0065","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.critrevonc.2013.06.011","article-title":"Lung cancer in never smokers: disease characteristics and risk factors","volume":"88","author":"Pallis","year":"2013","journal-title":"Crit. Rev. Oncol. Hematol."},{"issue":"4","key":"10.1016\/j.lungcan.2016.01.006_bib0070","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s10147-010-0160-8","article-title":"Non-small cell lung cancer in never smokers as a representative non-smoking-associated lung cancer: epidemiology and clinical features","volume":"16","author":"Yano","year":"2011","journal-title":"Int. J. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.lungcan.2016.01.006_bib0075","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1158\/1078-0432.CCR-10-1773","article-title":"Long exposure of environmental tobacco smoke associated with activating EGFR mutations in never-smokers with non-small cell lung cancer","volume":"17","author":"Kawaguchi","year":"2011","journal-title":"Clin. Cancer Res."},{"issue":"19","key":"10.1016\/j.lungcan.2016.01.006_bib0080","doi-asserted-by":"crossref","first-page":"6092","DOI":"10.1158\/1078-0432.CCR-08-0332","article-title":"Epidermal growth factor receptor mutations in small cell lung cancer","volume":"14","author":"Tatematsu","year":"2008","journal-title":"Clin. Cancer Res."},{"issue":"7","key":"10.1016\/j.lungcan.2016.01.006_bib0085","first-page":"2141","article-title":"Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen","volume":"62","author":"Stabile","year":"2002","journal-title":"Cancer Res."},{"issue":"4","key":"10.1016\/j.lungcan.2016.01.006_bib0090","first-page":"538","article-title":"The development of targeted therapy in small cell lung cancer","volume":"5","author":"Zhang","year":"2016","journal-title":"J. Thorac. Dis."}],"container-title":["Lung Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016950021630006X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016950021630006X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T02:56:56Z","timestamp":1537066616000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016950021630006X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":18,"alternative-id":["S016950021630006X"],"URL":"https:\/\/doi.org\/10.1016\/j.lungcan.2016.01.006","relation":{},"ISSN":["0169-5002"],"issn-type":[{"type":"print","value":"0169-5002"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Small-cell lung cancer in never-smokers: A case series","name":"articletitle","label":"Article Title"},{"value":"Lung Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lungcan.2016.01.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Ireland Ltd. Published by Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}