{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T04:11:35Z","timestamp":1767845495692,"version":"3.49.0"},"reference-count":12,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Wellcome Trust clinical PhD fellowship"},{"name":"CRUK clinical PhD fellowship"},{"name":"Wellcome Trust Senior Fellow in Clinical Science"},{"DOI":"10.13039\/501100000833","name":"Rosetrees Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000833","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009855","name":"Roy Castle Lung Cancer Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009855","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Welton Trust"},{"name":"Garfield Weston Trust and UCLH Charitable Foundation"},{"name":"Department of Health\u2019s NIHR Biomedical Research Centre\u2019s funding scheme"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","lungcancerjournal.info","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Lung Cancer"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.lungcan.2018.12.004","type":"journal-article","created":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T03:24:32Z","timestamp":1543980272000},"page":"164-166","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Retrospective response analysis of BAP1 expression to predict the clinical activity of systemic cytotoxic chemotherapy in mesothelioma"],"prefix":"10.1016","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4346-2112","authenticated-orcid":false,"given":"Neelam","family":"Kumar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doraid","family":"Alrifai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna K.","family":"Kolluri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9009-421X","authenticated-orcid":false,"given":"Elizabeth K.","family":"Sage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Ishii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi","family":"Guppy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaine","family":"Borg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Falzon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Nankivell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew G.","family":"Nicholson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6634-5939","authenticated-orcid":false,"given":"Sam M.","family":"Janes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.lungcan.2018.12.004_bib0005","doi-asserted-by":"crossref","first-page":"p. 565","DOI":"10.1097\/JTO.0000000000000471","article-title":"High incidence of somatic BAP1 alterations in sporadic malignant mesothelioma","volume":"10","author":"Nasu","year":"2015","journal-title":"J. Thorac. Oncol."},{"issue":"22","key":"10.1016\/j.lungcan.2018.12.004_bib0010","doi-asserted-by":"crossref","first-page":"p. 6499","DOI":"10.1158\/0008-5472.CAN-14-0221","article-title":"Deubiquitination of gamma-tubulin by BAP1 prevents chromosome instability in breast cancer cells","volume":"74","author":"Zarrizi","year":"2014","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.lungcan.2018.12.004_bib0015","doi-asserted-by":"crossref","first-page":"p. 285","DOI":"10.1073\/pnas.1309085110","article-title":"Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair","volume":"111","author":"Yu","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"11","key":"10.1016\/j.lungcan.2018.12.004_bib0020","doi-asserted-by":"crossref","first-page":"p. 1344","DOI":"10.1038\/nm.3947","article-title":"Loss of BAP1 function leads to EZH2-dependent transformation","volume":"21","author":"LaFave","year":"2015","journal-title":"Nat. Med."},{"issue":"8","key":"10.1016\/j.lungcan.2018.12.004_bib0025","doi-asserted-by":"crossref","first-page":"p. 1309","DOI":"10.1016\/j.jtho.2017.03.023","article-title":"A novel BRCA1-associated Protein-1 isoform affects response of mesothelioma cells to drugs impairing BRCA1-mediated DNA repair","volume":"12","author":"Parrotta","year":"2017","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2018.12.004_bib0030","first-page":"7","article-title":"Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells","author":"Kolluri","year":"2018","journal-title":"Elife"},{"issue":"7","key":"10.1016\/j.lungcan.2018.12.004_bib0035","doi-asserted-by":"crossref","first-page":"p. 651","DOI":"10.1097\/PAT.0000000000000002","article-title":"BAP1 protein loss by immunohistochemistry: a potentially useful tool for prognostic prediction in patients with uveal melanoma","volume":"45","author":"Shah","year":"2013","journal-title":"Pathology"},{"issue":"7659","key":"10.1016\/j.lungcan.2018.12.004_bib0040","doi-asserted-by":"crossref","first-page":"p. 549","DOI":"10.1038\/nature22798","article-title":"BAP1 regulates IP3R3-mediated Ca(2+) flux to mitochondria suppressing cell transformation","volume":"546","author":"Bononi","year":"2017","journal-title":"Nature"},{"issue":"9625","key":"10.1016\/j.lungcan.2018.12.004_bib0045","doi-asserted-by":"crossref","first-page":"p. 1685","DOI":"10.1016\/S0140-6736(08)60727-8","article-title":"Active symptom control with or without chemotherapy in the treatment of patients with malignant pleural mesothelioma (MS01): a multicentre randomised trial","volume":"371","author":"Muers","year":"2008","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.lungcan.2018.12.004_bib0050","doi-asserted-by":"crossref","first-page":"p. 1246","DOI":"10.1016\/j.jtho.2016.04.028","article-title":"Consensus report of the 2015 Weinman International Conference on mesothelioma","volume":"11","author":"Carbone","year":"2016","journal-title":"J. Thorac. Oncol."},{"issue":"12","key":"10.1016\/j.lungcan.2018.12.004_bib0055","doi-asserted-by":"crossref","first-page":"p. 1853","DOI":"10.4161\/cbt.6.12.5164","article-title":"BRCA1 regulates gamma-tubulin binding to centrosomes","volume":"6","author":"Sankaran","year":"2007","journal-title":"Cancer Biol. Ther."},{"issue":"2","key":"10.1016\/j.lungcan.2018.12.004_bib0060","doi-asserted-by":"crossref","first-page":"p. 200","DOI":"10.1002\/path.3979","article-title":"BRCA1 is an essential mediator of vinorelbine-induced apoptosis in mesothelioma","volume":"227","author":"Busacca","year":"2012","journal-title":"J. Pathol."}],"container-title":["Lung Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169500218306901?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169500218306901?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T14:31:40Z","timestamp":1573050700000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169500218306901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":12,"alternative-id":["S0169500218306901"],"URL":"https:\/\/doi.org\/10.1016\/j.lungcan.2018.12.004","relation":{},"ISSN":["0169-5002"],"issn-type":[{"value":"0169-5002","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Retrospective response analysis of BAP1 expression to predict the clinical activity of systemic cytotoxic chemotherapy in mesothelioma","name":"articletitle","label":"Article Title"},{"value":"Lung Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lungcan.2018.12.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}