{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:08:48Z","timestamp":1786993728520,"version":"build-2736575974"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:00:00Z","timestamp":1706659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22K16208"],"award-info":[{"award-number":["22K16208"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","lungcancerjournal.info","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Lung Cancer"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.lungcan.2024.107498","type":"journal-article","created":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T11:15:59Z","timestamp":1706958959000},"page":"107498","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Clinical application of the Lung Cancer Compact PanelTM using various types of cytological specimens in patients with lung cancer"],"prefix":"10.1016","volume":"189","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5241-3486","authenticated-orcid":false,"given":"Kei","family":"Kunimasa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motohiro","family":"Tamiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takako","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahisa","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7188-674X","authenticated-orcid":false,"given":"Akito","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Kojitani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichiro","family":"Honma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2000-7472","authenticated-orcid":false,"given":"Kazumi","family":"Nishino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lungcan.2024.107498_b0005","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.annonc.2022.12.009","article-title":"Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","volume":"34","author":"Hendriks","year":"2023","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0010","doi-asserted-by":"crossref","unstructured":"Singh N, Jaiyesimi IA, Ismaila N et al. Therapy for Stage IV Non-Small-Cell Lung Cancer With Driver Alterations: ASCO Living Guideline, Version 2023.1. J Clin Oncol 2023:Jco2300281.","DOI":"10.1200\/JCO.23.00282"},{"key":"10.1016\/j.lungcan.2024.107498_b0015","doi-asserted-by":"crossref","first-page":"497","DOI":"10.6004\/jnccn.2022.0025","article-title":"Non-Small Cell Lung Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology","volume":"20","author":"Ettinger","year":"2022","journal-title":"J. Natl. Compr. Canc. Netw."},{"key":"10.1016\/j.lungcan.2024.107498_b0020","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1056\/NEJMoa1913662","article-title":"Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC","volume":"382","author":"Ramalingam","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0025","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/j.annonc.2020.04.478","article-title":"Updated overall survival and final progression-free survival data for patients with treatment-naive advanced ALK-positive non-small-cell lung cancer in the ALEX study","volume":"31","author":"Mok","year":"2020","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0030","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1016\/j.jtho.2021.07.035","article-title":"Brigatinib Versus Crizotinib in ALK Inhibitor-Naive Advanced ALK-Positive NSCLC: Final Results of Phase 3 ALTA-1L Trial","volume":"16","author":"Camidge","year":"2021","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0035","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/S2213-2600(22)00437-4","article-title":"Efficacy and safety of first-line lorlatinib versus crizotinib in patients with advanced, ALK-positive non-small-cell lung cancer: updated analysis of data from the phase 3, randomised, open-label CROWN study","volume":"11","author":"Solomon","year":"2023","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0040","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1056\/NEJMoa2309457","article-title":"First-Line Selpercatinib or Chemotherapy and Pembrolizumab in RET Fusion-Positive NSCLC","volume":"389","author":"Zhou","year":"2023","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0045","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1093\/annonc\/mdz131","article-title":"Crizotinib in ROS1-rearranged advanced non-small-cell lung cancer (NSCLC): updated results, including overall survival, from PROFILE 1001","volume":"30","author":"Shaw","year":"2019","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0050","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/S1470-2045(17)30608-3","article-title":"Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label, phase 3 trial","volume":"18","author":"Wu","year":"2017","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0055","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/S1470-2045(19)30634-5","article-title":"Ramucirumab plus erlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer (RELAY): a randomised, double-blind, placebo-controlled, phase 3 trial","volume":"20","author":"Nakagawa","year":"2019","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0060","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2021-002891","article-title":"Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer","volume":"9","author":"Negrao","year":"2021","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.lungcan.2024.107498_b0065","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1093\/annonc\/mdz167","article-title":"Immune checkpoint inhibitors for patients with advanced lung cancer and oncogenic driver alterations: results from the IMMUNOTARGET registry","volume":"30","author":"Mazieres","year":"2019","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0070","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/s41571-022-00718-x","article-title":"At the crossroads of immunotherapy for oncogene-addicted subsets of NSCLC","volume":"20","author":"Otano","year":"2023","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0075","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.annonc.2020.07.014","article-title":"Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working Group","volume":"31","author":"Mosele","year":"2020","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2022.100570","article-title":"How to read a next-generation sequencing report-what oncologists need to know","volume":"7","author":"Schmid","year":"2022","journal-title":"ESMO Open"},{"key":"10.1016\/j.lungcan.2024.107498_b0085","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1038\/s41586-020-2481-8","article-title":"The National Lung Matrix Trial of personalized therapy in lung cancer","volume":"583","author":"Middleton","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.lungcan.2024.107498_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.lungcan.2023.107190","article-title":"Clinical application of the AMOY 9-in-1 panel to lung cancer patients","volume":"179","author":"Kunimasa","year":"2023","journal-title":"Lung Cancer"},{"key":"10.1016\/j.lungcan.2024.107498_b0095","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.2217\/fon-2020-0332","article-title":"Improvement strategies for successful next-generation sequencing analysis of lung cancer","volume":"16","author":"Kunimasa","year":"2020","journal-title":"Future Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0100","doi-asserted-by":"crossref","first-page":"2524","DOI":"10.1111\/cas.15752","article-title":"Real-world study of next-generation sequencing diagnostic biomarker testing for patients with lung cancer in Japan","volume":"114","author":"Takahashi","year":"2023","journal-title":"Cancer Sci."},{"key":"10.1016\/j.lungcan.2024.107498_b0105","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1002\/cam4.4632","article-title":"Comparison of sampling methods for next generation sequencing for patients with lung cancer","volume":"11","author":"Kunimasa","year":"2022","journal-title":"Cancer Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0110","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/1759-7714.14738","article-title":"Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report","volume":"14","author":"Kunimasa","year":"2023","journal-title":"Thorac Cancer"},{"key":"10.1016\/j.lungcan.2024.107498_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.lungcan.2023.107390","article-title":"Usefulness of bronchial washing fluid for detection of EGFR mutations in non-small cell lung cancer","volume":"186","author":"Ryu","year":"2023","journal-title":"Lung Cancer"},{"key":"10.1016\/j.lungcan.2024.107498_b0120","doi-asserted-by":"crossref","DOI":"10.1177\/15330338231202881","article-title":"Bronchoalveolar Lavage as Potential Diagnostic Specimens to Genetic Testing in Advanced Nonsmall Cell Lung Cancer","volume":"22","author":"Lin","year":"2023","journal-title":"Technol. Cancer Res. Treat."},{"key":"10.1016\/j.lungcan.2024.107498_b0125","doi-asserted-by":"crossref","first-page":"17632","DOI":"10.1002\/cam4.6380","article-title":"Protocol optimization of a targeted sequencing panel for genomic profiling of bronchoalveolar lavage fluid in lung cancer","volume":"12","author":"Sather","year":"2023","journal-title":"Cancer Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0130","first-page":"444","article-title":"Rapid staining with the modified Gill-Shorr method for reliable, rapid bronchoscopic diagnosis","volume":"50","author":"Omiya","year":"2006","journal-title":"Acta Cytol."},{"key":"10.1016\/j.lungcan.2024.107498_b0135","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1159\/000480089","article-title":"Next-Generation Sequencing in Diagnostic Pathology","volume":"84","author":"Ilyas","year":"2017","journal-title":"Pathobiology"},{"key":"10.1016\/j.lungcan.2024.107498_b0140","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.jmoldx.2017.01.011","article-title":"Guidelines for Validation of Next-Generation Sequencing-Based Oncology Panels: A Joint Consensus Recommendation of the Association for Molecular Pathology and College of American Pathologists","volume":"19","author":"Jennings","year":"2017","journal-title":"J. Mol. Diagn."},{"key":"10.1016\/j.lungcan.2024.107498_b0145","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/cncy.22381","article-title":"Utilization of cytology smears improves success rates of RNA-based next-generation sequencing gene fusion assays for clinically relevant predictive biomarkers","volume":"129","author":"Ramani","year":"2021","journal-title":"Cancer Cytopathol."},{"key":"10.1016\/j.lungcan.2024.107498_b0150","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/cncy.22076","article-title":"Molecular testing of residual cytology samples: Rethink, reclaim, repurpose","volume":"127","author":"Roy-Chowdhuri","year":"2019","journal-title":"Cancer Cytopathol"},{"key":"10.1016\/j.lungcan.2024.107498_b0155","doi-asserted-by":"crossref","DOI":"10.5858\/arpa.2019-0411-OA","article-title":"Detection of EGFR T790M Mutation by Droplet Digital Polymerase Chain Reaction in Lung Carcinoma Cytology Samples","author":"Nizamaddin","year":"2020","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0160","doi-asserted-by":"crossref","unstructured":"Kato K, Okami J, Nakamura H et al. Analytical Performance of a Highly Sensitive System to Detect Gene Variants Using Next-Generation Sequencing for Lung Cancer Companion Diagnostics. Diagnostics (Basel) 2023;13.","DOI":"10.3390\/diagnostics13081476"},{"key":"10.1016\/j.lungcan.2024.107498_b0165","first-page":"14","article-title":"A Prospective Validation Study of Lung Cancer Gene Panel Testing Using Cytological Specimens","author":"Morikawa","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.lungcan.2024.107498_b0170","doi-asserted-by":"crossref","unstructured":"Vestergaard LK, Oliveira DNP, Poulsen TS, H\u00f8gdall CK, H\u00f8gdall EV. Oncomine\u2122 Comprehensive Assay v3 vs. Oncomine\u2122 Comprehensive Assay Plus. Cancers (Basel) 2021;13.","DOI":"10.3390\/cancers13205230"},{"key":"10.1016\/j.lungcan.2024.107498_b0175","doi-asserted-by":"crossref","unstructured":"Amin MB, Greene FL, Edge SB et al. The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more \u201cpersonalized\u201d approach to cancer staging. CA Cancer J Clin 2017;67:93-99.","DOI":"10.3322\/caac.21388"},{"key":"10.1016\/j.lungcan.2024.107498_b0180","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/1471-2164-5-88","article-title":"Comparison of frozen and RNALater solid tissue storage methods for use in RNA expression microarrays","volume":"5","author":"Mutter","year":"2004","journal-title":"BMC Genomics"},{"key":"10.1016\/j.lungcan.2024.107498_b0185","doi-asserted-by":"crossref","first-page":"20975","DOI":"10.1038\/s41598-021-00355-x","article-title":"Optimization of RNA extraction methods from human metabolic tissue samples of the COMET biobank","volume":"11","author":"Nouvel","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lungcan.2024.107498_b0190","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/bmt.2012.244","article-title":"Investigation of the freely available easy-to-use software 'EZR' for medical statistics","volume":"48","author":"Kanda","year":"2013","journal-title":"Bone Marrow Transplant."},{"key":"10.1016\/j.lungcan.2024.107498_b0195","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.annonc.2022.05.520","article-title":"ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group","volume":"33","author":"Pascual","year":"2022","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0200","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.cllc.2022.11.007","article-title":"Liquid Biopsy Versus Tissue Biopsy to Determine Front Line Therapy in Metastatic Non-Small Cell Lung Cancer (NSCLC)","volume":"24","author":"Raez","year":"2023","journal-title":"Clin. Lung Cancer"},{"key":"10.1016\/j.lungcan.2024.107498_b0205","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.cllc.2021.10.001","article-title":"Clinical Outcomes for Plasma-Based Comprehensive Genomic Profiling Versus Standard-of-Care Tissue Testing in Advanced Non-Small Cell Lung Cancer","volume":"23","author":"Page","year":"2022","journal-title":"Clin. Lung Cancer"},{"key":"10.1016\/j.lungcan.2024.107498_b0210","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1158\/1078-0432.CCR-22-1749","article-title":"A Large-Scale Prospective Concordance Study of Plasma- and Tissue-Based Next-Generation Targeted Sequencing for Advanced Non-Small Cell Lung Cancer (LC-SCRUM-Liquid)","volume":"29","author":"Sugimoto","year":"2023","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.lungcan.2024.107498_b0215","doi-asserted-by":"crossref","first-page":"4691","DOI":"10.1158\/1078-0432.CCR-19-0624","article-title":"Clinical Utility of Comprehensive Cell-free DNA Analysis to Identify Genomic Biomarkers in Patients with Newly Diagnosed Metastatic Non-small Cell Lung Cancer","volume":"25","author":"Leighl","year":"2019","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.lungcan.2024.107498_b0220","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1002\/cncy.22313","article-title":"Current and future trends in non-small cell lung cancer biomarker testing: The American experience","volume":"128","author":"VanderLaan","year":"2020","journal-title":"Cancer Cytopathol."},{"key":"10.1016\/j.lungcan.2024.107498_b0225","doi-asserted-by":"crossref","DOI":"10.1177\/03000605221132708","article-title":"The usefulness of liquid-based cytology of bronchoalveolar lavage fluid combined with bronchial brush specimens in lung cancer diagnosis","volume":"50","author":"Ma","year":"2022","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.lungcan.2024.107498_b0230","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1177\/0300891620960218","article-title":"Diagnostic role of liquid-based cytology of bronchial lavage fluid in addition to bronchial brushing specimens in lung cancer","volume":"107","author":"Cao","year":"2021","journal-title":"Tumori"},{"key":"10.1016\/j.lungcan.2024.107498_b0235","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1056\/NEJMoa1409405","article-title":"Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence","volume":"371","author":"Genovese","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0240","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1182\/blood.2023022222","article-title":"Causes and consequences of clonal hematopoiesis","volume":"142","author":"Weeks","year":"2023","journal-title":"Blood"},{"key":"10.1016\/j.lungcan.2024.107498_b0245","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1056\/NEJMoa1616288","article-title":"Tracking the Evolution of Non-Small-Cell Lung Cancer","volume":"376","author":"Jamal-Hanjani","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0250","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41586-023-05783-5","article-title":"The evolution of lung cancer and impact of subclonal selection in TRACERx","volume":"616","author":"Frankell","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.lungcan.2024.107498_b0255","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/s41586-023-05776-4","article-title":"Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA","volume":"616","author":"Abbosh","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.lungcan.2024.107498_b0260","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.amjmed.2022.04.017","article-title":"Malignant Pleural Effusion: Presentation, Diagnosis, and Management","volume":"135","author":"Gayen","year":"2022","journal-title":"Am. J. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0265","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1001\/jamaoncol.2018.4305","article-title":"Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non-Small Cell Lung Cancer","volume":"5","author":"Aggarwal","year":"2019","journal-title":"JAMA Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1200\/PO.18.00191","article-title":"Orthogonal Comparison of Four Plasma NGS Tests With Tumor Suggests Technical Factors are a Major Source of Assay Discordance","volume":"3","author":"Stetson","year":"2019","journal-title":"JCO Precis. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0275","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.ccell.2023.03.018","article-title":"Genomic mapping of metastatic organotropism in lung adenocarcinoma","volume":"41","author":"Lengel","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.lungcan.2024.107498_b0280","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/j.jtho.2023.06.017","article-title":"Genomic Alterations and the Incidence of Brain Metastases in Advanced and Metastatic NSCLC: A Systematic Review and Meta-Analysis","volume":"18","author":"Gillespie","year":"2023","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0285","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1200\/JOP.19.00357","article-title":"Management of Brain Metastases in Non\u2013Small-Cell Lung Cancer","volume":"15","author":"Ernani","year":"2019","journal-title":"J. Oncol. Pract."},{"key":"10.1016\/j.lungcan.2024.107498_b0290","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.jtho.2019.01.007","article-title":"Clinical Utility of Cerebrospinal Fluid Cell-Free DNA as Liquid Biopsy for Leptomeningeal Metastases in ALK-Rearranged NSCLC","volume":"14","author":"Zheng","year":"2019","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0295","doi-asserted-by":"crossref","first-page":"1611391","DOI":"10.3389\/pore.2023.1611391","article-title":"Concordance analysis of cerebrospinal fluid with the tumor tissue for integrated diagnosis in gliomas based on next-generation sequencing","volume":"29","author":"Wang","year":"2023","journal-title":"Pathol. Oncol. Res."},{"key":"10.1016\/j.lungcan.2024.107498_b0300","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s11060-023-04471-8","article-title":"Cerebrospinal fluid circulating tumour DNA genotyping and survival analysis in lung adenocarcinoma with leptomeningeal metastases","volume":"165","author":"Bai","year":"2023","journal-title":"J. Neurooncol"},{"key":"10.1016\/j.lungcan.2024.107498_b0305","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/annonc\/mdy009","article-title":"Unique genetic profiles from cerebrospinal fluid cell-free DNA in leptomeningeal metastases of EGFR-mutant non-small-cell lung cancer: a new medium of liquid biopsy","volume":"29","author":"Li","year":"2018","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107498_b0310","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/nm.1789","article-title":"Circulating mutant DNA to assess tumor dynamics","volume":"14","author":"Diehl","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0315","doi-asserted-by":"crossref","DOI":"10.20892\/j.issn.2095-3941.2023.0381","article-title":"Bronchoalveolar lavage fluid assessment facilitates precision medicine for lung cancer","author":"Zhang","year":"2023","journal-title":"Cancer Biol. Med."},{"key":"10.1016\/j.lungcan.2024.107498_b0320","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.cllc.2021.09.002","article-title":"Genetic Profiling of Cell-Free DNA From Pleural Effusion in Advanced Lung Cancer as a Surrogate for Tumor Tissue and Revealed Additional Clinical Actionable Targets","volume":"23","author":"Tu","year":"2022","journal-title":"Clin. Lung Cancer"},{"key":"10.1016\/j.lungcan.2024.107498_b0325","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1002\/1878-0261.12713","article-title":"Molecular testing on bronchial washings for the diagnosis and predictive assessment of lung cancer","volume":"14","author":"Roncarati","year":"2020","journal-title":"Mol. Oncol."}],"container-title":["Lung Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016950022400031X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016950022400031X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T13:08:08Z","timestamp":1759237688000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016950022400031X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":65,"alternative-id":["S016950022400031X"],"URL":"https:\/\/doi.org\/10.1016\/j.lungcan.2024.107498","relation":{},"ISSN":["0169-5002"],"issn-type":[{"value":"0169-5002","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical application of the Lung Cancer Compact PanelTM using various types of cytological specimens in patients with lung cancer","name":"articletitle","label":"Article Title"},{"value":"Lung Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lungcan.2024.107498","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"107498"}}