{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T03:48:15Z","timestamp":1785815295445,"version":"3.56.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","lungcancerjournal.info","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Lung Cancer"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.lungcan.2024.107860","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T23:30:32Z","timestamp":1719444632000},"page":"107860","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["ROS1 fusions in resected stage I-III adenocarcinoma: Results from the European Thoracic Oncology Platform Lungscape project"],"prefix":"10.1016","volume":"194","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3016-2989","authenticated-orcid":false,"given":"Ernst-Jan M.","family":"Speel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4367-4497","authenticated-orcid":false,"given":"Urania","family":"Dafni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Thunnissen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Hendrik R\u00fcschoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathal","family":"O'Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0086-0265","authenticated-orcid":false,"given":"Jacek","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith M.","family":"Kerr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5970-1803","authenticated-orcid":false,"given":"Lukas","family":"Bubendorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Sansano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8233-709X","authenticated-orcid":false,"given":"Leena","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Kriegsmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atilio","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8690-3811","authenticated-orcid":false,"given":"Kim","family":"Monkhorst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line","family":"Bille Madsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Hernandez Losa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Biernat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albrecht","family":"Stenzinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"R\u00fcland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8808-4952","authenticated-orcid":false,"given":"Lisa M.","family":"Hillen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nesa","family":"Marti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8866-9881","authenticated-orcid":false,"given":"Miguel A.","family":"Molina-Vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tereza","family":"Dellaporta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5572-7894","authenticated-orcid":false,"given":"Roswitha","family":"Kammler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solange","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4815-8870","authenticated-orcid":false,"given":"Rolf A.","family":"Stahel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8628-5814","authenticated-orcid":false,"given":"Stephen P.","family":"Finn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teodora","family":"Radonic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lungcan.2024.107860_b0005","doi-asserted-by":"crossref","first-page":"641","DOI":"10.3390\/curroncol29020057","article-title":"ROS-1 Fusions in Non-Small-Cell Lung Cancer: Evidence to Date","volume":"29","author":"Gendarme","year":"2022","journal-title":"Curr. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0010","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1056\/NEJMoa1406766","article-title":"Crizotinib in ROS1-rearranged non-small-cell lung cancer","volume":"371","author":"Shaw","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.lungcan.2024.107860_b0015","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S1470-2045(19)30690-4","article-title":"Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1\u20132 trials","volume":"21","author":"Drilon","year":"2020","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtocrr.2022.100332","article-title":"Long-Term Efficacy and Safety of Entrectinib in ROS1 Fusion-Positive NSCLC","volume":"3","author":"Drilon","year":"2022","journal-title":"JTO Clin. Res. Reports."},{"key":"10.1016\/j.lungcan.2024.107860_b0025","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1158\/2159-8290.CD-18-0484","article-title":"Repotrectinib (TPX-0005) Is a Next-Generation ROS1\/TRK\/ALK Inhibitor That Potently Inhibits ROS1\/TRK\/ALK Solvent- Front Mutations","volume":"8","author":"Drilon","year":"2018","journal-title":"Cancer Discov."},{"key":"10.1016\/j.lungcan.2024.107860_b0030","doi-asserted-by":"crossref","first-page":"9017","DOI":"10.1200\/JCO.2023.41.16_suppl.9017","article-title":"Intracranial and systemic efficacy of repotrectinib in advanced ROS1 fusion-positive (ROS1+) non-small cell lung cancer (NSCLC) and central nervous system metastases (CNS mets) in the phase 1\/2 TRIDENT-1","volume":"41","author":"Lin","year":"2023","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0035","doi-asserted-by":"crossref","unstructured":"Drilon A, Camidge DR, Lin JJ, Kim SW, Solomon BJ, Dziadziuszko R, Besse B, Goto K, de Langen AJ, Wolf J, Lee KH, Popat S, Springfeld C, Nagasaka M, Felip E, Yang N, Velcheti V, Lu S, Kao S, Dooms C, Krebs MG, Yao W, Beg MS, Hu X, Moro-Sibilot D, Cheema P, Stopatschinskaja S, Mehta M, Trone D, Graber A, Sims G, Yuan Y, Cho BC; TRIDENT-1 Investigators. Repotrectinib inROS1Fusion-Positive Non-Small-Cell Lung Cancer. N Engl J Med. 2024 Jan 11;390(2):118-131. doi: 10.1056\/NEJMoa2302299. PMID: 38197815.","DOI":"10.1056\/NEJMoa2302299"},{"key":"10.1016\/j.lungcan.2024.107860_b0040","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.annonc.2022.12.009","article-title":"Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up\u2606","volume":"34","author":"Hendriks","year":"2023","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0045","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.cell.2007.11.025","article-title":"Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer","volume":"131","author":"Rikova","year":"2007","journal-title":"Cell."},{"key":"10.1016\/j.lungcan.2024.107860_b0050","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1038\/nm.2658","article-title":"ROS1 and ALK fusions in lung cancer","volume":"18","author":"Takeuchi","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.lungcan.2024.107860_b0055","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1002\/1878-0261.12789","article-title":"Molecular and clinicopathological characteristics of ROS1-rearranged non-small-cell lung cancers identified by next-generation sequencing","volume":"14","author":"Cui","year":"2020","journal-title":"Mol. Oncol."},{"issue":"10","key":"10.1016\/j.lungcan.2024.107860_b0060","doi-asserted-by":"crossref","first-page":"3919","DOI":"10.21037\/jtd.2017.09.79","article-title":"ALK and ROS1 rearrangements, coexistence and treatment in epidermal growth factor receptor-wild type lung adenocarcinoma: a multicenter study of 732 cases","volume":"9","author":"Song","year":"2017","journal-title":"J Thorac Dis."},{"key":"10.1016\/j.lungcan.2024.107860_b0065","article-title":"Peripheral Lung Squamous Carcinoma With ROS1 Rearrangement Sensitive to Crizotinib: A Case Report","volume":"11","author":"Yang","year":"2021","journal-title":"Front. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0070","doi-asserted-by":"crossref","first-page":"e193","DOI":"10.1016\/j.jtho.2017.08.021","article-title":"ALK and ROS1 Double-Rearranged Lung Squamous Cell Carcinoma Responding to Crizotinib Treatment: A Case Report","volume":"12","author":"Li","year":"2017","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.yexmp.2020.104548","article-title":"High prevalence of ROS1 gene rearrangement detected by FISH in EGFR and ALK negative lung adenocarcinoma","volume":"117","author":"Xu","year":"2020","journal-title":"Exp Mol Pathol."},{"issue":"12","key":"10.1016\/j.lungcan.2024.107860_b0080","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.21037\/tlcr-22-504","article-title":"Comparison of ROS1-rearrangement detection methods in a cohort of surgically resected non-small cell lung carcinomas","volume":"11","author":"Thurfjell","year":"2022","journal-title":"Transl Lung Cancer Res."},{"key":"10.1016\/j.lungcan.2024.107860_b0085","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s13000-023-01357-1","article-title":"Evaluation of ROS1 expression and rearrangements in a large cohort of early-stage lung cancer","volume":"18","author":"Dyrbekk","year":"2023","journal-title":"Diagn. Pathol."},{"key":"10.1016\/j.lungcan.2024.107860_b0090","first-page":"47","article-title":"Prevalence of ROS1 fusion in Chinese patients with non-small cell lung cancer, Thorac","volume":"10","author":"Zhang","year":"2019","journal-title":"Cancer."},{"key":"10.1016\/j.lungcan.2024.107860_b0095","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/j.jtho.2018.05.041","article-title":"Comparison of Molecular Testing Modalities for Detection of ROS1 Rearrangements in a Cohort of Positive Patient Samples","volume":"13","author":"Davies","year":"2018","journal-title":"J. Thorac. Oncol."},{"issue":"6","key":"10.1016\/j.lungcan.2024.107860_b0100","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.jmoldx.2019.06.006","article-title":"Comparison of in Situ and Extraction-Based Methods for the Detection of ROS1 Rearrangements in Solid Tumors","volume":"21","author":"Heydt","year":"2019","journal-title":"J Mol Diagn."},{"key":"10.1016\/j.lungcan.2024.107860_b0105","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s00428-016-2000-3","article-title":"Testing for ROS1 in non-small cell lung cancer: a review with recommendations","volume":"469","author":"Bubendorf","year":"2016","journal-title":"Virchows Arch."},{"key":"10.1016\/j.lungcan.2024.107860_b0110","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1097\/PAS.0b013e3182960fa7","article-title":"ROS1 immunohistochemistry for detection of ROS1-rearranged lung adenocarcinomas","volume":"37","author":"Sholl","year":"2013","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.lungcan.2024.107860_b0115","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/j.jtho.2019.03.024","article-title":"Multicenter Evaluation of a Novel ROS1 Immunohistochemistry Assay (SP384) for Detection of ROS1 Rearrangements in a Large Cohort of Lung Adenocarcinoma Patients","volume":"14","author":"Hofman","year":"2019","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.lungcan.2019.03.012","article-title":"A retrospective cohort study of PD-L1 prevalence, molecular associations and clinical outcomes in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape Project","volume":"131","author":"Kerr","year":"2019","journal-title":"Lung Cancer."},{"key":"10.1016\/j.lungcan.2024.107860_b0125","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.jtho.2017.11.117","article-title":"Evaluation of NGS and RT-PCR Methods for ALK Rearrangement in European NSCLC Patients: Results from the European Thoracic Oncology Platform Lungscape Project","volume":"13","author":"Letovanec","year":"2018","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0130","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/annonc\/mdx629","article-title":"Prevalence and clinical association of gene mutations through multiplex mutation testing in patients with NSCLC: Results from the ETOP Lungscape Project","volume":"29","author":"Kerr","year":"2018","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0135","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/j.jtho.2021.02.016","article-title":"Prognostic Impact of KRAS G12C Mutation in Patients With NSCLC: Results From the European Thoracic Oncology Platform Lungscape Project","volume":"16","author":"Finn","year":"2021","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0140","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1097\/JTO.0000000000000320","article-title":"Lungscape: Resected non-small-cell lung cancer outcome by clinical and pathological parameters","volume":"9","author":"Peters","year":"2014","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0145","doi-asserted-by":"crossref","unstructured":"McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM; Statistics Subcommittee of the NCI-EORTC Working Group on Cancer Diagnostics. REporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer. 2005 Aug 22;93(4):387-91. doi: 10.1038\/sj.bjc.6602678. PMID: 16106245; PMCID: PMC2361579.","DOI":"10.1038\/sj.bjc.6602678"},{"key":"10.1016\/j.lungcan.2024.107860_b0150","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/s00428-010-0952-2","article-title":"HER2 diagnostics in gastric cancer-guideline validation and development of standardized immunohistochemical testing","volume":"457","author":"Ruschoff","year":"2010","journal-title":"Virchows Arch"},{"key":"10.1016\/j.lungcan.2024.107860_b0155","doi-asserted-by":"crossref","first-page":"735","DOI":"10.5858\/arpa.2019-0085-OA","article-title":"Correlation of ROS1 immunohistochemistry with ROS1 fusion status determined by fluorescence in situ hybridization","volume":"144","author":"Huang","year":"2020","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.lungcan.2024.107860_b0160","doi-asserted-by":"crossref","unstructured":"Nambirajan A, Sood R, Khatoon W, Malik PS, Mohan A, Jain D. Concordance of Immunohistochemistry and Fluorescence In Situ Hybridization in the Detection of Anaplastic Lymphoma Kinase (ALK) and Ros Proto-oncogene 1 (ROS1) Gene Rearrangements in Non-Small Cell Lung Carcinoma: A 4.5-Year Experience Highlighting Challenges and Pitfalls. Arch Pathol Lab Med. 2023 Dec 6. doi: 10.5858\/arpa.2023-0229-OA. Epub ahead of print. PMID: 38054562.","DOI":"10.5858\/arpa.2023-0229-OA"},{"issue":"8","key":"10.1016\/j.lungcan.2024.107860_b0165","doi-asserted-by":"crossref","first-page":"922","DOI":"10.5858\/arpa.2017-0502-RA","article-title":"Biomarkers for ALK and ROS1 in Lung Cancer: Immunohistochemistry and Fluorescent In Situ Hybridization","volume":"142","author":"Luk","year":"2018","journal-title":"Arch Pathol Lab Med."},{"key":"10.1016\/j.lungcan.2024.107860_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtho.2021.01.1619","article-title":"RET Fluorescence In Situ Hybridization Analysis Is a Sensitive but Highly Unspecific Screening Method for RET Fusions in Lung Cancer","volume":"16","author":"Radonic","year":"2021","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0175","first-page":"1","article-title":"Detecting ALK, ROS1, and RET fusions and the MET\u0394ex14 splicing variant in liquid biopsies of non-small-cell lung cancer patients using RNA-based techniques","author":"Gim\u00e9nez-Capit\u00e1n","year":"2023","journal-title":"Mol. Oncol."},{"issue":"25","key":"10.1016\/j.lungcan.2024.107860_b0180","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.1200\/JCO.2013.54.5921","article-title":"Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma: results from the European Thoracic Oncology Platform Lungscape Project","volume":"32","author":"Blackhall","year":"2014","journal-title":"J Clin Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0185","unstructured":"Frankell AM, Dietzen M, Al Bakir M, Lim EL, Karasaki T, Ward S, Veeriah S, Colliver E, Huebner A, Bunkum A, Hill MS, Grigoriadis K, Moore DA, Black JRM, Liu WK, Thol K, Pich O, Watkins TBK, Naceur-Lombardelli C, Cook DE, Salgado R, Wilson GA, Bailey C, Angelova M, Bentham R, Mart\u00ednez-Ruiz C, Abbosh C, Nicholson AG, Le Quesne J, Biswas D, Rosenthal R, Puttick C, Hessey S, Lee C, Prymas P, Toncheva A, Smith J, Xing W, Nicod J, Price G, Kerr KM, Naidu B, Middleton G, Blyth KG, Fennell DA, Forster MD, Lee SM, Falzon M, Hewish M, Shackcloth MJ, Lim E, Benafif S, Russell P, Boleti E, Krebs MG, Lester JF, Papadatos-Pastos D, Ahmad T, Thakrar RM, Lawrence D, Navani N, Janes SM, Dive C, Blackhall FH, Summers Y, Cave J, Marafioti T, Herrero J, Quezada SA, Peggs KS, Schwarz RF, Van Loo P, Miedema DM, Birkbak NJ, Hiley CT, Hackshaw A, Zaccaria S; TRACERx Consortium; Jamal-Hanjani M, McGranahan N, Swanton C. The evolution of lung cancer and impact of subclonal selection in TRACERx. Nature. 2023 Apr;616(7957):525-533. doi: 10.1038\/s41586-023-05783-5. Epub 2023 Apr 12. PMID: 37046096; PMCID: PMC10115649."},{"key":"10.1016\/j.lungcan.2024.107860_b0190","unstructured":"Al Bakir M, Huebner A, Mart\u00ednez-Ruiz C, Grigoriadis K, Watkins TBK, Pich O, Moore DA, Veeriah S, Ward S, Laycock J, Johnson D, Rowan A, Razaq M, Akther M, Naceur-Lombardelli C, Prymas P, Toncheva A, Hessey S, Dietzen M, Colliver E, Frankell AM, Bunkum A, Lim EL, Karasaki T, Abbosh C, Hiley CT, Hill MS, Cook DE, Wilson GA, Salgado R, Nye E, Stone RK, Fennell DA, Price G, Kerr KM, Naidu B, Middleton G, Summers Y, Lindsay CR, Blackhall FH, Cave J, Blyth KG, Nair A, Ahmed A, Taylor MN, Procter AJ, Falzon M, Lawrence D, Navani N, Thakrar RM, Janes SM, Papadatos-Pastos D, Forster MD, Lee SM, Ahmad T, Quezada SA, Peggs KS, Van Loo P, Dive C, Hackshaw A, Birkbak NJ, Zaccaria S; TRACERx Consortium; Jamal-Hanjani M, McGranahan N, Swanton C. The evolution of non-small cell lung cancer metastases in TRACERx. Nature. 2023 Apr;616(7957):534-542. doi: 10.1038\/s41586-023-05729-x. Epub 2023 Apr 12. PMID: 37046095; PMCID: PMC10115651."},{"key":"10.1016\/j.lungcan.2024.107860_b0195","doi-asserted-by":"crossref","unstructured":"[39] Jamal-Hanjani M, Wilson GA, McGranahan N, Birkbak NJ, Watkins TBK, Veeriah S, Shafi S, Johnson DH, Mitter R, Rosenthal R, Salm M, Horswell S, Escudero M, Matthews N, Rowan A, Chambers T, Moore DA, Turajlic S, Xu H, Lee SM, Forster MD, Ahmad T, Hiley CT, Abbosh C, Falzon M, Borg E, Marafioti T, Lawrence D, Hayward M, Kolvekar S, Panagiotopoulos N, Janes SM, Thakrar R, Ahmed A, Blackhall F, Summers Y, Shah R, Joseph L, Quinn AM, Crosbie PA, Naidu B, Middleton G, Langman G, Trotter S, Nicolson M, Remmen H, Kerr K, Chetty M, Gomersall L, Fennell DA, Nakas A, Rathinam S, Anand G, Khan S, Russell P, Ezhil V, Ismail B, Irvin-Sellers M, Prakash V, Lester JF, Kornaszewska M, Attanoos R, Adams H, Davies H, Dentro S, Taniere P, O'Sullivan B, Lowe HL, Hartley JA, Iles N, Bell H, Ngai Y, Shaw JA, Herrero J, Szallasi Z, Schwarz RF, Stewart A, Quezada SA, Le Quesne J, Van Loo P, Dive C, Hackshaw A, Swanton C; TRACERx Consortium. Tracking the Evolution of Non-Small-Cell Lung Cancer. N Engl J Med. 2017 Jun 1;376(22):2109-2121. doi: 10.1056\/NEJMoa1616288. Epub 2017 Apr 26. PMID: 28445112.","DOI":"10.1056\/NEJMoa1616288"},{"key":"10.1016\/j.lungcan.2024.107860_b0200","series-title":"_R: A Language and Environment for Statistical Computing_","author":"R Core Team","year":"2023"},{"key":"10.1016\/j.lungcan.2024.107860_b0205","doi-asserted-by":"crossref","DOI":"10.3389\/fepid.2023.1109853","article-title":"Patterns of care and survival for lung cancer: Results of the European population-based high-resolution study","volume":"3","author":"Sant","year":"2023","journal-title":"Front. Epidemiol."},{"key":"10.1016\/j.lungcan.2024.107860_b0210","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/his.13076","article-title":"Screening for ROS1 gene rearrangements in non-small-cell lung cancers using immunohistochemistry with FISH confirmation is an effective method to identify this rare target","volume":"70","author":"Selinger","year":"2017","journal-title":"Histopathology."},{"key":"10.1016\/j.lungcan.2024.107860_b0215","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1097\/JTO.0000000000000232","article-title":"Clinical and the prognostic characteristics of lung adenocarcinoma patients with ros1 fusion in comparison with other driver mutations in east asian populations","volume":"9","author":"Chen","year":"2014","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0225","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/his.12379","article-title":"ROS1 expression and translocations in non-small-cell lung cancer: Clinicopathological analysis of 1478 cases","volume":"65","author":"Warth","year":"2014","journal-title":"Histopathology."},{"key":"10.1016\/j.lungcan.2024.107860_b0230","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1016\/j.jtho.2019.07.005","article-title":"Assessment of a New ROS1 Immunohistochemistry Clone (SP384) for the Identification of ROS1 Rearrangements in Patients with Non-Small Cell Lung Carcinoma: the ROSING Study","volume":"14","author":"Conde","year":"2019","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0235","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jtho.2016.08.137","article-title":"High Prevalence of Concomitant Oncogene Mutations in Prospectively Identified Patients with ROS1-Positive Metastatic Lung Cancer","volume":"12","author":"Wiesweg","year":"2017","journal-title":"J. Thorac. Oncol."},{"issue":"11","key":"10.1016\/j.lungcan.2024.107860_b0240","article-title":"Co-Occurring Potentially Actionable Oncogenic Drivers in Non-Small Cell Lung Cancer","volume":"16","author":"Zhao","year":"2021","journal-title":"Front Oncol."},{"key":"10.1016\/j.lungcan.2024.107860_b0245","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.lungcan.2023.02.007","article-title":"The impact of impaired tissue fixation in resected non-small-cell lung cancer on protein deterioration and DNA degradation","volume":"178","author":"Butter","year":"2023","journal-title":"Lung Cancer."},{"key":"10.1016\/j.lungcan.2024.107860_b0250","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00428-019-02595-9","article-title":"O. behalf of ETOP, Impact of delayed and prolonged fixation on the evaluation of immunohistochemical staining on lung carcinoma resection specimen","volume":"475","author":"van Seijen","year":"2019","journal-title":"Virchows Arch."},{"key":"10.1016\/j.lungcan.2024.107860_b0255","doi-asserted-by":"crossref","unstructured":"Roemen GJM, zur Hausen A, Speel EJM: Adequate tissue for adequate diagnosis: what do we really need? In: ERS Monogr (Lung Cancer) 68, 119-135, 2015. Ed: Dingemans AMC, Reck M, Westeel V. European Respiratory Society 2015. Charlesworth Press, Wakefield, UK.","DOI":"10.1183\/2312508X.10010014"}],"container-title":["Lung Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169500224003945?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169500224003945?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,6]],"date-time":"2024-10-06T11:08:22Z","timestamp":1728212902000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169500224003945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":50,"alternative-id":["S0169500224003945"],"URL":"https:\/\/doi.org\/10.1016\/j.lungcan.2024.107860","relation":{},"ISSN":["0169-5002"],"issn-type":[{"value":"0169-5002","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ROS1 fusions in resected stage I-III adenocarcinoma: Results from the European Thoracic Oncology Platform Lungscape project","name":"articletitle","label":"Article Title"},{"value":"Lung Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lungcan.2024.107860","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"107860"}}