{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:19:03Z","timestamp":1762082343774,"version":"build-2065373602"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100012543","name":"Shanghai Science and Technology Development Foundation","doi-asserted-by":"publisher","award":["JCYJ20190808145805515","JCYJ20210324093612032"],"award-info":[{"award-number":["JCYJ20190808145805515","JCYJ20210324093612032"]}],"id":[{"id":"10.13039\/100012543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81973152","82073646","82273707"],"award-info":[{"award-number":["81973152","82073646","82273707"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515012503"],"award-info":[{"award-number":["2021A1515012503"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Mechanisms of Ageing and Development"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.mad.2023.111777","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T04:32:30Z","timestamp":1674621150000},"page":"111777","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Lower intensity of physical activity strengthens the effect of dietary inflammatory index on the risk of all-cause and cause-specific mortality"],"prefix":"10.1016","volume":"211","author":[{"given":"Jinli","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuying","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijun","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianze","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huifang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueru","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengmeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weifeng","family":"Huo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yajuan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yamin","family":"Ke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Longkang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenkai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaobing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fulan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongsheng","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.mad.2023.111777_bib1","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.clnu.2018.05.003","article-title":"Dietary inflammatory index and all-cause mortality in large cohorts: the SUN and PREDIMED studies","volume":"38","author":"Ana Garcia-Arellano","year":"2019","journal-title":"Clin. Nutr."},{"issue":"7","key":"10.1016\/j.mad.2023.111777_bib2","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0009-9120(00)00162-4","article-title":"Estimation of LDL cholesterol based on the Friedewald formula and on apo B levels","volume":"33","author":"Bairaktari","year":"2000","journal-title":"Clin. Biochem"},{"issue":"24","key":"10.1016\/j.mad.2023.111777_bib3","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1136\/bjsports-2020-102955","article-title":"World Health Organization 2020 guidelines on physical activity and sedentary behaviour","volume":"54","author":"Bull","year":"2020","journal-title":"Br. J. Sports Med"},{"issue":"7","key":"10.1016\/j.mad.2023.111777_bib4","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1007\/s12603-019-1221-y","article-title":"Associations between dietary inflammatory index scores and inflammatory biomarkers among older adults in the lothian birth Cohort 1936 study","volume":"23","author":"Corley","year":"2019","journal-title":"J. Nutr. Health Aging"},{"issue":"8","key":"10.1016\/j.mad.2023.111777_bib5","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1249\/01.MSS.0000078924.61453.FB","article-title":"International physical activity questionnaire: 12-country reliability and validity","volume":"35","author":"Craig","year":"2003","journal-title":"Med Sci. Sports Exerc"},{"issue":"3","key":"10.1016\/j.mad.2023.111777_bib6","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1007\/s00394-016-1158-4","article-title":"Association between diet-related inflammation, all-cause, all-cancer, and cardiovascular disease mortality, with special focus on prediabetics: findings from NHANES III","volume":"56","author":"Deng","year":"2017","journal-title":"Eur. J. Nutr."},{"issue":"12","key":"10.1016\/j.mad.2023.111777_bib7","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1038\/s41591-019-0675-0","article-title":"Chronic inflammation in the etiology of disease across the life span","volume":"25","author":"Furman","year":"2019","journal-title":"Nat. Med."},{"issue":"4","key":"10.1016\/j.mad.2023.111777_bib8","doi-asserted-by":"crossref","first-page":"897","DOI":"10.3945\/ajcn.115.116863","article-title":"Dietary inflammatory index and telomere length in subjects with a high cardiovascular disease risk from the PREDIMED-NAVARRA study: cross-sectional and longitudinal analyses over 5y","volume":"102","author":"Garc\u00eda-Calz\u00f3n","year":"2015","journal-title":"Am. J. Clin. Nutr."},{"issue":"6","key":"10.1016\/j.mad.2023.111777_bib9","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrneph.2017.51","article-title":"The immunology of atherosclerosis","volume":"13","author":"Gister\u00e5","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"issue":"4","key":"10.1016\/j.mad.2023.111777_bib10","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.metabol.2014.01.002","article-title":"Impact of baseline physical activity and diet behavior on metabolic syndrome in a pharmaceutical trial: results from NAVIGATOR","volume":"63","author":"Huffman","year":"2014","journal-title":"Metabolism"},{"key":"10.1016\/j.mad.2023.111777_bib11","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.atherosclerosis.2016.04.015","article-title":"Inflammation biomarkers and mortality prediction in patients with type 2 diabetes (ZODIAC-27)","volume":"250","author":"Landman","year":"2016","journal-title":"Atherosclerosis"},{"issue":"12","key":"10.1016\/j.mad.2023.111777_bib12","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1007\/s00125-019-04972-0","article-title":"Dietary inflammatory index and type 2 diabetes risk in a prospective cohort of 70,991 women followed for 20 years: the mediating role of BMI","volume":"62","author":"Laouali","year":"2019","journal-title":"Diabetologia"},{"issue":"10","key":"10.1016\/j.mad.2023.111777_bib13","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1038\/s41430-020-0602-y","article-title":"Dietary inflammatory index and bladder cancer risk: a prospective study","volume":"74","author":"Luo","year":"2020","journal-title":"Eur. J. Clin. Nutr."},{"issue":"2","key":"10.1016\/j.mad.2023.111777_bib14","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/00913847.2018.1443665","article-title":"The association between physical activity and dietary inflammatory index on mortality risk in U.S. adults","volume":"46","author":"Meghan","year":"2018","journal-title":"Physician Sportsmed."},{"key":"10.1016\/j.mad.2023.111777_bib15","doi-asserted-by":"crossref","first-page":"l2323","DOI":"10.1136\/bmj.l2323","article-title":"Physical activity trajectories and mortality: population based cohort study","volume":"365","author":"Mok","year":"2019","journal-title":"Bmj"},{"issue":"1","key":"10.1016\/j.mad.2023.111777_bib16","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/eurpub\/ckx060","article-title":"Association between dietary inflammatory index, and cause-specific mortality in the MONICA\/KORA Augsburg Cohort Study","volume":"28","author":"Nitin Shivappa","year":"2018","journal-title":"Eur. J. Public Health"},{"issue":"9","key":"10.1016\/j.mad.2023.111777_bib17","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.2105\/AJPH.2013.301492","article-title":"Food sources of saturated fat and the association with mortality: a meta-analysis","volume":"103","author":"O'Sullivan","year":"2013","journal-title":"Am. J. Public Health"},{"issue":"2","key":"10.1016\/j.mad.2023.111777_bib18","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/jnci\/djz069","article-title":"Insulin resistance and cancer-specific and all-cause mortality in postmenopausal women: the Women's health initiative","volume":"112","author":"Pan","year":"2020","journal-title":"J. Natl. Cancer Inst."},{"issue":"11","key":"10.1016\/j.mad.2023.111777_bib19","doi-asserted-by":"crossref","first-page":"4467","DOI":"10.1021\/jf900612n","article-title":"Modulation of inflammatory genes by natural dietary bioactive compounds","volume":"57","author":"Pan","year":"2009","journal-title":"J. Agric. Food Chem."},{"issue":"2","key":"10.1016\/j.mad.2023.111777_bib20","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.clnu.2018.04.002","article-title":"Dietary inflammatory potential and risk of mortality in metabolically healthy and unhealthy phenotypes among overweight and obese adults","volume":"38","author":"Park","year":"2019","journal-title":"Clin. Nutr."},{"issue":"3","key":"10.1016\/j.mad.2023.111777_bib21","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1161\/01.CIR.0000052939.59093.45","article-title":"Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association","volume":"107","author":"Pearson","year":"2003","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.mad.2023.111777_bib22","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/s41569-021-00647-9","article-title":"Prevention of atherosclerosis from childhood","volume":"19","author":"Raitakari","year":"2022","journal-title":"Nat. Rev. Cardiol."},{"issue":"7","key":"10.1016\/j.mad.2023.111777_bib23","doi-asserted-by":"crossref","DOI":"10.3390\/nu10070831","article-title":"Association between dietary inflammatory index, C-reactive protein and metabolic syndrome: a cross-sectional study","volume":"10","author":"Ren","year":"2018","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.mad.2023.111777_bib24","first-page":"10","article-title":"Mediterranean diet and physical activity decrease the initiation of cardiovascular drug use in high cardiovascular risk individuals: a Cohort Study","author":"Rib\u00f3-Coll","year":"2021","journal-title":"Antioxidants"},{"issue":"11","key":"10.1016\/j.mad.2023.111777_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/nu11112560","article-title":"The association between dietary inflammatory index (DII) and cancer risk in korea: a prospective Cohort study within the KoGES-HEXA study","volume":"11","author":"Ryu","year":"2019","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.mad.2023.111777_bib26","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/eurheartj\/ehy713","article-title":"Prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in older adults","volume":"40","author":"Shanbhag","year":"2019","journal-title":"Eur. Heart J."},{"issue":"8","key":"10.1016\/j.mad.2023.111777_bib27","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1017\/S1368980013002115","article-title":"Designing and developing a literature-derived, population-based dietary inflammatory index","volume":"17","author":"Shivappa","year":"2014","journal-title":"Public Health Nutr."},{"issue":"4","key":"10.1016\/j.mad.2023.111777_bib28","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1017\/S000711451400395X","article-title":"Associations between dietary inflammatory index and inflammatory markers in the Asklepios Study","volume":"113","author":"Shivappa","year":"2015","journal-title":"Br. J. Nutr."},{"issue":"5","key":"10.1016\/j.mad.2023.111777_bib29","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1007\/s00394-015-1005-z","article-title":"Association between inflammatory potential of diet and mortality among women in the Swedish Mammography Cohort","volume":"55","author":"Shivappa","year":"2016","journal-title":"Eur. J. Nutr."},{"issue":"4","key":"10.1016\/j.mad.2023.111777_bib30","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1007\/s00394-015-0967-1","article-title":"Association between inflammatory potential of diet and mortality in the Iowa Women's Health study","volume":"55","author":"Shivappa","year":"2016","journal-title":"Eur. J. Nutr."},{"issue":"9","key":"10.1016\/j.mad.2023.111777_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/nu9091043","article-title":"Dietary inflammatory index and colorectal cancer risk-a meta-analysis","volume":"9","author":"Shivappa","year":"2017","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.mad.2023.111777_bib32","doi-asserted-by":"crossref","DOI":"10.3390\/nu10020200","article-title":"Dietary inflammatory index and cardiovascular risk and mortality-a meta-analysis","volume":"10","author":"Shivappa","year":"2018","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.mad.2023.111777_bib33","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/nri.2017.142","article-title":"NF-\u03baB, inflammation, immunity and cancer: coming of age","volume":"18","author":"Taniguchi","year":"2018","journal-title":"Nat. Rev. Immunol."},{"issue":"11","key":"10.1016\/j.mad.2023.111777_bib34","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/0895-4356(90)90018-K","article-title":"Characteristics of individuals and long term reproducibility of dietary reports: the Tecumseh diet methodology study","volume":"43","author":"Thompson","year":"1990","journal-title":"J. Clin. Epidemiol."},{"issue":"3","key":"10.1016\/j.mad.2023.111777_bib35","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1365-2796.2005.01450.x","article-title":"Homocysteine as a risk factor for CVD mortality in men with other CVD risk factors: the Kuopio Ischaemic heart disease risk factor (KIHD) study","volume":"257","author":"Virtanen","year":"2005","journal-title":"J. Intern Med"},{"key":"10.1016\/j.mad.2023.111777_bib36","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.arr.2018.09.002","article-title":"Telomere length and all-cause mortality: a meta-analysis","volume":"48","author":"Wang","year":"2018","journal-title":"Ageing Res Rev."},{"issue":"2","key":"10.1016\/j.mad.2023.111777_bib37","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1001\/jamainternmed.2020.6331","article-title":"Association of physical activity intensity with mortality: a National Cohort study of 403\u00a0681 US adults","volume":"181","author":"Wang","year":"2021","journal-title":"JAMA Intern Med"},{"issue":"10","key":"10.1016\/j.mad.2023.111777_bib38","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1038\/s41590-021-01023-y","article-title":"Macrophage IRX3 promotes diet-induced obesity and metabolic inflammation","volume":"22","author":"Yao","year":"2021","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.mad.2023.111777_bib39","unstructured":"Yuexin Yang et al. China Food Composition Tables, Standard Edition, 6th Revision [S].[J]. Peking University Medical Press, 2018:"},{"key":"10.1016\/j.mad.2023.111777_bib40","unstructured":"J. Zhang, Y. Feng, X. Yang, et al. Dose-response Association of the Dietary Inflammatory Potential With All-Cause and Cause-Specific Mortality[J]. Adv Nutr, 2022a:"},{"issue":"5","key":"10.1016\/j.mad.2023.111777_bib41","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1093\/advances\/nmac049","article-title":"Dose-response association of dietary inflammatory potential with all-cause and cause-specific mortality","volume":"13","author":"Zhang","year":"2022","journal-title":"Adv. Nutr."},{"issue":"3","key":"10.1016\/j.mad.2023.111777_bib42","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1093\/ije\/dyaa204","article-title":"Cohort profile: the rural Chinese Cohort study","volume":"50","author":"Zhang","year":"2021","journal-title":"Int J. Epidemiol."},{"issue":"11","key":"10.1016\/j.mad.2023.111777_bib43","doi-asserted-by":"crossref","first-page":"e553","DOI":"10.1016\/S2468-2667(19)30155-0","article-title":"Age at natural menopause and risk of incident cardiovascular disease: a pooled analysis of individual patient data","volume":"4","author":"Zhu","year":"2019","journal-title":"Lancet Public Health"}],"container-title":["Mechanisms of Ageing and Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0047637423000039?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0047637423000039?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T17:48:42Z","timestamp":1758649722000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0047637423000039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":43,"alternative-id":["S0047637423000039"],"URL":"https:\/\/doi.org\/10.1016\/j.mad.2023.111777","relation":{},"ISSN":["0047-6374"],"issn-type":[{"type":"print","value":"0047-6374"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lower intensity of physical activity strengthens the effect of dietary inflammatory index on the risk of all-cause and cause-specific mortality","name":"articletitle","label":"Article Title"},{"value":"Mechanisms of Ageing and Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mad.2023.111777","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111777"}}