{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T02:35:23Z","timestamp":1794105323480,"version":"4.8.0"},"reference-count":343,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T00:00:00Z","timestamp":1686614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Aspects of Medicine"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.mam.2023.101193","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T13:16:22Z","timestamp":1686921382000},"page":"101193","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":121,"special_numbering":"C","title":["Neuroprotection in glaucoma: Mechanisms beyond intraocular pressure lowering"],"prefix":"10.1016","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8301-7358","authenticated-orcid":false,"given":"James R.","family":"Tribble","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2218-9951","authenticated-orcid":false,"given":"Flora","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heberto","family":"Quintero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sana","family":"El Hajji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Bell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1430-0760","authenticated-orcid":false,"given":"Adriana","family":"Di Polo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6194-8397","authenticated-orcid":false,"given":"Pete A.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mam.2023.101193_bib1","first-page":"2171","volume":"vol. 17","author":"Abu-Amero","year":"2011"},{"key":"10.1016\/j.mam.2023.101193_bib2","first-page":"1955","volume":"vol. 18","author":"Abu-Amero","year":"2012"},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib3","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.1167\/iovs.05-1639","article-title":"Mitochondrial abnormalities in patients with primary open-angle glaucoma","volume":"47","author":"Abu-Amero","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib4","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/aje\/kwr329","article-title":"Apolipoprotein E gene associations in age-related macular degeneration: the Melbourne Collaborative Cohort Study","volume":"175","author":"Adams","year":"2012","journal-title":"Am. J. Epidemiol."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib5","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1093\/brain\/awy142","article-title":"Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury","volume":"141","author":"Agostinone","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.mam.2023.101193_bib6","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/bs.pbr.2015.04.012","article-title":"Retinal ganglion cell dendrite pathology and synapse loss: implications for glaucoma","volume":"220","author":"Agostinone","year":"2015","journal-title":"Prog. Brain Res."},{"issue":"9","key":"10.1016\/j.mam.2023.101193_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22094672","article-title":"Insulin signaling as a therapeutic target in glaucomatous neurodegeneration","volume":"22","author":"Al Hussein Al Awamlh","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2023.101193_bib8","doi-asserted-by":"crossref","first-page":"227","DOI":"10.3389\/fncel.2017.00227","article-title":"The P2X7 receptor primes IL-1\u03b2 and the NLRP3 inflammasome in astrocytes exposed to mechanical strain","volume":"11","author":"Albalawi","year":"2017","journal-title":"Front. Cell. Neurosci."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib9","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/79944","article-title":"OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28","volume":"26","author":"Alexander","year":"2000","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1002472","article-title":"NMNAT2:HSP90 complex mediates proteostasis in proteinopathies","volume":"14","author":"Ali","year":"2016","journal-title":"PLoS Biol."},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib11","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1001\/archopht.121.11.1582","article-title":"Pathophysiology of the optic neuropathy associated with Friedreich ataxia","volume":"121","author":"Alldredge","year":"2003","journal-title":"Arch. Ophthalmol."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib12","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.preteyeres.2011.11.002","article-title":"The molecular basis of retinal ganglion cell death in glaucoma","volume":"31","author":"Almasieh","year":"2012","journal-title":"Prog. Retin. Eye Res."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib13","doi-asserted-by":"crossref","first-page":"4566","DOI":"10.1073\/pnas.0407357102","article-title":"High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma","volume":"102","author":"Anderson","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"5686","key":"10.1016\/j.mam.2023.101193_bib14","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1126\/science.1098014","article-title":"Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration","volume":"305","author":"Araki","year":"2004","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib15","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrneurol.2017.185","article-title":"Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums","volume":"14","author":"Arnold","year":"2018","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.mam.2023.101193_bib16","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.pneurobio.2016.10.001","article-title":"Insulin resistance and Parkinson's disease: a new target for disease modification?","volume":"145\u2013146","author":"Athauda","year":"2016","journal-title":"Prog. Neurobiol."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib17","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1007\/s00439-002-0711-9","article-title":"Investigating the association between OPA1 polymorphisms and glaucoma: comparison between normal tension and high tension primary open angle glaucoma","volume":"110","author":"Aung","year":"2002","journal-title":"Hum. Genet."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib18","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/s00439-001-0645-7","article-title":"A major marker for normal tension glaucoma: association with polymorphisms in the OPA1 gene","volume":"110","author":"Aung","year":"2002","journal-title":"Hum. Genet."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib19","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1083\/jcb.124.6.903","article-title":"Ultrastructural analysis of the autophagic process in yeast: detection of autophagosomes and their characterization","volume":"124","author":"Baba","year":"1994","journal-title":"J. Cell Biol."},{"issue":"40","key":"10.1016\/j.mam.2023.101193_bib20","doi-asserted-by":"crossref","first-page":"13291","DOI":"10.1523\/JNEUROSCI.1189-10.2010","article-title":"Targeting NMNAT1 to axons and synapses transforms its neuroprotective potency in vivo","volume":"30","author":"Babetto","year":"2010","journal-title":"J. Neurosci."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib21","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/ng.3482","article-title":"Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma","volume":"48","author":"Bailey","year":"2016","journal-title":"Nat. Genet."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib22","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1167\/iovs.03-1121","article-title":"The epsilon2 and epsilon4 alleles of the apolipoprotein gene are associated with age-related macular degeneration","volume":"45","author":"Baird","year":"2004","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib23","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/humu.20288","article-title":"Apolipoprotein (APOE) gene is associated with progression of age-related macular degeneration (AMD)","volume":"27","author":"Baird","year":"2006","journal-title":"Hum. Mutat."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0070760","article-title":"Mitochondrial genome analysis of primary open angle glaucoma patients","volume":"8","author":"Banerjee","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2023.101193_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2020.100916","article-title":"Inflammation in Glaucoma: from the back to the front of the eye, and beyond","volume":"83","author":"Baudouin","year":"2021","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.mam.2023.101193_bib26","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3389\/fnins.2015.00204","article-title":"Aberrant insulin signaling in Alzheimer's disease: current knowledge","volume":"9","author":"Bedse","year":"2015","journal-title":"Front. Neurosci."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib27","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1111\/j.1460-9568.2008.06426.x","article-title":"The WldS gene delays axonal but not somatic degeneration in a rat glaucoma model","volume":"28","author":"Beirowski","year":"2008","journal-title":"Eur. J. Neurosci."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib28","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s13024-021-00466-z","article-title":"AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma","volume":"16","author":"Belforte","year":"2021","journal-title":"Mol. Neurodegener."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib29","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1080\/02713683.2016.1205629","article-title":"Elevated regulatory T cell levels in glaucoma patients in comparison to healthy controls","volume":"42","author":"Bell","year":"2017","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.mam.2023.101193_bib30","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41420-020-0257-4","article-title":"Age related retinal Ganglion cell susceptibility in context of autophagy deficiency","volume":"6","author":"Bell","year":"2020","journal-title":"Cell Death Dis."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib31","doi-asserted-by":"crossref","first-page":"4368","DOI":"10.1523\/JNEUROSCI.14-07-04368.1994","article-title":"Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats","volume":"14","author":"Berkelaar","year":"1994","journal-title":"J. Neurosci."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib32","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/s40478-020-01094-2","article-title":"Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease","volume":"8","author":"Bevan","year":"2020","journal-title":"Acta Neuropathol. Commun."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib33","doi-asserted-by":"crossref","first-page":"fcaa101","DOI":"10.1093\/braincomms\/fcaa101","article-title":"OPA1 deficiency accelerates hippocampal synaptic remodelling and age-related deficits in learning and memory","volume":"2","author":"Bevan","year":"2020","journal-title":"Brain Commun."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib34","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1111\/ejn.13295","article-title":"Brain-derived neurotrophic factor prevents dendritic retraction of adult mouse retinal ganglion cells","volume":"44","author":"Binley","year":"2016","journal-title":"Eur. J. Neurosci."},{"issue":"Pt B","key":"10.1016\/j.mam.2023.101193_bib35","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.neuropharm.2017.09.016","article-title":"Reduced brain insulin signaling: a seminal process in Alzheimer's disease pathogenesis","volume":"136","author":"Bloom","year":"2018","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib36","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/mt.2015.198","article-title":"Virus-mediated EpoR76E therapy slows optic nerve axonopathy in experimental glaucoma","volume":"24","author":"Bond","year":"2016","journal-title":"Mol. Ther."},{"issue":"13","key":"10.1016\/j.mam.2023.101193_bib37","doi-asserted-by":"crossref","first-page":"4186","DOI":"10.1523\/JNEUROSCI.16-13-04186.1996","article-title":"Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2","volume":"16","author":"Bonfanti","year":"1996","journal-title":"J. Neurosci."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib38","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/jnc.14070","article-title":"Involvement of microglia in early axoglial alterations of the optic nerve induced by experimental glaucoma","volume":"142","author":"Bordone","year":"2017","journal-title":"J. Neurochem."},{"issue":"10","key":"10.1016\/j.mam.2023.101193_bib39","doi-asserted-by":"crossref","first-page":"3226","DOI":"10.1093\/brain\/awab184","article-title":"Pharmacological SARM1 inhibition protects axon structure and function in paclitaxel-induced peripheral neuropathy","volume":"144","author":"Bosanac","year":"2021","journal-title":"Brain"},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib40","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043602","article-title":"Early reduction of microglia activation by irradiation in a model of chronic glaucoma","volume":"7","author":"Bosco","year":"2012","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib41","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1167\/iovs.07-1337","article-title":"Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA\/2J mouse model of glaucoma","volume":"49","author":"Bosco","year":"2008","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib42","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1002\/cne.22516","article-title":"Early microglia activation in a mouse model of chronic glaucoma","volume":"519","author":"Bosco","year":"2011","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.mam.2023.101193_bib43","first-page":"1074","volume":"vol. 17","author":"Bosley","year":"2011"},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib44","doi-asserted-by":"crossref","first-page":"e156","DOI":"10.1111\/j.1442-9071.2011.02595.x","article-title":"Association of tumour necrosis factor-alpha -308 G\/A polymorphism with primary open-angle glaucoma","volume":"40","author":"Bozkurt","year":"2012","journal-title":"Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.mam.2023.101193_bib45","doi-asserted-by":"crossref","first-page":"526","DOI":"10.3389\/fnins.2016.00526","article-title":"Loss of fractalkine signaling exacerbates axon transport dysfunction in a chronic model of glaucoma","volume":"10","author":"Breen","year":"2016","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.mam.2023.101193_bib46","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3389\/fendo.2013.00048","article-title":"GABA and glutamate uptake and metabolism in retinal glial (m\u00fcller) cells","volume":"4","author":"Bringmann","year":"2013","journal-title":"Front. Endocrinol."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib47","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/0197-4580(87)90144-8","article-title":"Neurons numbers and dendritic extent in normal aging and Alzheimer's disease","volume":"8","author":"Brizzee","year":"1987","journal-title":"Neurobiol. Aging"},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib48","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/s00439-001-0660-8","article-title":"The role of mtDNA background in disease expression: a new primary LHON mutation associated with Western Eurasian haplogroup J","volume":"110","author":"Brown","year":"2002","journal-title":"Hum. Genet."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib49","doi-asserted-by":"crossref","first-page":"e427","DOI":"10.1111\/aos.12096","article-title":"Expression of insulin-like growth factor 1 receptor in rat retina following optic nerve injury","volume":"91","author":"Bu","year":"2013","journal-title":"Acta Ophthalmol."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib50","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.chembiol.2018.01.012","article-title":"Identification of the nicotinamide salvage pathway as a new toxification route for antimetabolites","volume":"25","author":"Buonvicino","year":"2018","journal-title":"Cell Chem. Biol."},{"issue":"24","key":"10.1016\/j.mam.2023.101193_bib51","doi-asserted-by":"crossref","first-page":"14368","DOI":"10.1073\/pnas.2336098100","article-title":"Time-restricted role for dendritic activation of the mTOR-p70S6K pathway in the induction of late-phase long-term potentiation in the CA1","volume":"100","author":"Cammalleri","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"44","key":"10.1016\/j.mam.2023.101193_bib52","doi-asserted-by":"crossref","first-page":"14717","DOI":"10.1523\/JNEUROSCI.2770-14.2014","article-title":"Unique function of Kinesin Kif5A in localization of mitochondria in axons","volume":"34","author":"Campbell","year":"2014","journal-title":"J. Neurosci."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib53","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.bbabio.2009.02.024","article-title":"Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders","volume":"1787","author":"Carelli","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-24709-1","article-title":"Local neuroplasticity in adult glaucomatous visual cortex","volume":"12","author":"Carvalho","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mam.2023.101193_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2020.100881","article-title":"Retinal energy metabolism in health and glaucoma","volume":"81","author":"Casson","year":"2021","journal-title":"Prog. Retin. Eye Res."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib56","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1442-9071.2012.02773.x","article-title":"Definition of glaucoma: clinical and experimental concepts","volume":"40","author":"Casson","year":"2012","journal-title":"Clin. Exp. Ophthalmol."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib57","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1002\/jnr.24411","article-title":"Mechanisms for the maintenance and regulation of axonal energy supply","volume":"97","author":"Chamberlain","year":"2019","journal-title":"J. Neurosci. Res."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib58","first-page":"966","article-title":"BDNF enhances retinal ganglion cell survival in cats with optic nerve damage","volume":"42","author":"Chen","year":"2001","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"30","key":"10.1016\/j.mam.2023.101193_bib59","doi-asserted-by":"crossref","first-page":"11181","DOI":"10.1073\/pnas.1402819111","article-title":"Caspase-8 promotes NLRP1\/NLRP3 inflammasome activation and IL-1\u03b2 production in acute glaucoma","volume":"111","author":"Chi","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib60","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1007\/s00401-011-0807-1","article-title":"The optic nerve head is the site of axonal transport disruption, axonal cytoskeleton damage and putative axonal regeneration failure in a rat model of glaucoma","volume":"121","author":"Chidlow","year":"2011","journal-title":"Acta Neuropathol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib61","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1167\/iovs.18-25536","article-title":"Distribution and activity of mitochondrial proteins in vascular and avascular retinas: implications for retinal metabolism","volume":"60","author":"Chidlow","year":"2019","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib62","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.2174\/1570159X16666180419121247","article-title":"Glaucoma pathogenesis and neurotrophins: focus on the molecular and genetic basis for therapeutic prospects","volume":"16","author":"Chitranshi","year":"2018","journal-title":"Curr. Neuropharmacol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib63","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/cmi.2009.110","article-title":"Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma","volume":"7","author":"Chiu","year":"2010","journal-title":"Cell. Mol. Immunol."},{"issue":"Pt 8","key":"10.1016\/j.mam.2023.101193_bib64","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1093\/brain\/awl174","article-title":"Early onset severe and late-onset mild Charcot-Marie-Tooth disease with mitofusin 2 (MFN2) mutations","volume":"129","author":"Chung","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.mam.2023.101193_bib65","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1146\/annurev-neuro-060909-153248","article-title":"Wallerian degeneration, wld(s), and nmnat","volume":"33","author":"Coleman","year":"2010","journal-title":"Annu. Rev. Neurosci."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib66","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/s41583-020-0269-3","article-title":"Programmed axon degeneration: from mouse to mechanism to medicine","volume":"21","author":"Coleman","year":"2020","journal-title":"Nat. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib67","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0197-4580(87)90127-8","article-title":"Neuron numbers and dendritic extent in normal aging and Alzheimer's disease","volume":"8","author":"Coleman","year":"1987","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.mam.2023.101193_bib68","first-page":"454","volume":"vol. 22","author":"Collins","year":"2016"},{"issue":"10","key":"10.1016\/j.mam.2023.101193_bib69","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0076627","article-title":"Mitochondrial sequence variation in African-American primary open-angle glaucoma patients","volume":"8","author":"Collins","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2023.101193_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2021.100976","article-title":"Detecting retinal cell stress and apoptosis with DARC: progression from lab to clinic","volume":"86","author":"Cordeiro","year":"2022","journal-title":"Prog. Retin. Eye Res."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib71","doi-asserted-by":"crossref","DOI":"10.3390\/biom11081239","article-title":"Targeting the NLRP3 inflammasome in glaucoma","volume":"11","author":"Coyle","year":"2021","journal-title":"Biomolecules"},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib72","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/j.ophtha.2012.11.043","article-title":"How does glaucoma look?: patient perception of visual field loss","volume":"120","author":"Crabb","year":"2013","journal-title":"Ophthalmology"},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib73","doi-asserted-by":"crossref","first-page":"5196","DOI":"10.1073\/pnas.0913141107","article-title":"Distal axonopathy with structural persistence in glaucomatous neurodegeneration","volume":"107","author":"Crish","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mam.2023.101193_bib74","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/978-1-4939-7407-8_15","article-title":"Anterograde tract tracing for assaying axonopathy and transport deficits in glaucoma","volume":"1695","author":"Crish","year":"2018","journal-title":"Methods Mol. Biol."},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib75","doi-asserted-by":"crossref","DOI":"10.1101\/pdb.prot087288","article-title":"Quantitation of apoptosis and necrosis by Annexin V binding, propidium iodide uptake, and flow cytometry","volume":"2016","author":"Crowley","year":"2016","journal-title":"Cold Spring Harb. Protoc."},{"issue":"6477","key":"10.1016\/j.mam.2023.101193_bib76","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1126\/science.aax6752","article-title":"Microglia monitor and protect neuronal function through specialized somatic purinergic junctions","volume":"367","author":"Cser\u00e9p","year":"2020","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib77","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20211071","article-title":"Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions","volume":"219","author":"Cs\u00e1sz\u00e1r","year":"2022","journal-title":"J. Exp. Med."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib78","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/ana.410330305","article-title":"Retinal ganglion cells in Alzheimer's disease and aging","volume":"33","author":"Curcio","year":"1993","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.mam.2023.101193_bib79","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.nbd.2013.07.001","article-title":"Proximal inhibition of p38 MAPK stress signaling prevents distal axonopathy","volume":"59","author":"Dapper","year":"2013","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.mam.2023.101193_bib80","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.mito.2017.05.010","article-title":"Topical Coenzyme Q10 demonstrates mitochondrial-mediated neuroprotection in a rodent model of ocular hypertension","volume":"36","author":"Davis","year":"2017","journal-title":"Mitochondrion"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib81","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1001\/jamaophthalmol.2021.4576","article-title":"Nicotinamide and pyruvate for neuroenhancement in open-angle glaucoma: a phase 2 randomized clinical trial","volume":"140","author":"De Moraes","year":"2022","journal-title":"JAMA Ophthalmol"},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib82","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/79936","article-title":"Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy","volume":"26","author":"Delettre","year":"2000","journal-title":"Nat. Genet."},{"issue":"44","key":"10.1016\/j.mam.2023.101193_bib83","doi-asserted-by":"crossref","first-page":"17444","DOI":"10.1523\/JNEUROSCI.5461-12.2013","article-title":"Differential progression of structural and functional alterations in distinct retinal ganglion cell types in a mouse model of glaucoma","volume":"33","author":"Della Santina","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mam.2023.101193_bib84","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.exer.2016.06.006","article-title":"Who's lost first? Susceptibility of retinal ganglion cell types in experimental glaucoma","volume":"158","author":"Della Santina","year":"2017","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.mam.2023.101193_bib85","doi-asserted-by":"crossref","first-page":"290","DOI":"10.3389\/fnins.2014.00290","article-title":"Anterograde transport blockade precedes deficits in retrograde transport in the visual projection of the DBA\/2J mouse model of glaucoma","volume":"8","author":"Dengler-Crish","year":"2014","journal-title":"Front. Neurosci."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib86","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.conb.2013.08.006","article-title":"Retinal ganglion cell maps in the brain: implications for visual processing","volume":"24","author":"Dhande","year":"2014","journal-title":"Curr. Opin. Neurobiol."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib87","doi-asserted-by":"crossref","first-page":"559","DOI":"10.4103\/1673-5374.155421","article-title":"Dendrite pathology and neurodegeneration: focus on mTOR","volume":"10","author":"Di Polo","year":"2015","journal-title":"Neural Regen. Res."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib88","doi-asserted-by":"crossref","first-page":"3978","DOI":"10.1073\/pnas.95.7.3978","article-title":"Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Muller cells temporarily rescues injured retinal ganglion cells","volume":"95","author":"Di Polo","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib89","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23073935","article-title":"The role of axonal transport in glaucoma","volume":"23","author":"Dias","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.mam.2023.101193_bib90","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1007\/s11427-019-1567-0","article-title":"BDNF improves axon transportation and rescues visual function in a rodent model of acute elevation of intraocular pressure","volume":"63","author":"Du","year":"2020","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.mam.2023.101193_bib91","doi-asserted-by":"crossref","first-page":"318","DOI":"10.3389\/fnins.2017.00318","article-title":"Interleukin-6 deficiency attenuates retinal ganglion cell axonopathy and glaucoma-related vision loss","volume":"11","author":"Echevarria","year":"2017","journal-title":"Front. Neurosci."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib92","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/s41593-020-00783-4","article-title":"Reactive astrocyte nomenclature, definitions, and future directions","volume":"24","author":"Escartin","year":"2021","journal-title":"Nat. Neurosci."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib93","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1016\/j.neuron.2017.02.022","article-title":"The SARM1 toll\/interleukin-1 receptor domain possesses intrinsic NAD","volume":"93","author":"Essuman","year":"2017","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib94","first-page":"273","article-title":"Mini-review: impaired axonal transport and glaucoma","volume":"41","author":"Fahy","year":"2016","journal-title":"Curr. Eye Res."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib95","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/j.ymthe.2022.01.035","article-title":"NMNAT2 is downregulated in glaucomatous RGCs, and RGC-specific gene therapy rescues neurodegeneration and visual function","volume":"30","author":"Fang","year":"2022","journal-title":"Mol. Ther."},{"issue":"20","key":"10.1016\/j.mam.2023.101193_bib96","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1212\/WNL.0b013e31821a441e","article-title":"MFN2 mutations cause severe phenotypes in most patients with CMT2A","volume":"76","author":"Feely","year":"2011","journal-title":"Neurology"},{"issue":"35","key":"10.1016\/j.mam.2023.101193_bib97","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2208457119","article-title":"Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain","volume":"119","author":"Feldman","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.mam.2023.101193_bib98","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0076938","article-title":"Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria","volume":"8","author":"Felici","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib99","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1167\/iovs.12-10791","article-title":"Sustained ocular hypertension induces dendritic degeneration of mouse retinal ganglion cells that depends on cell type and location","volume":"54","author":"Feng","year":"2013","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mam.2023.101193_bib100","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.exer.2018.03.007","article-title":"Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury","volume":"171","author":"Fernandes","year":"2018","journal-title":"Exp. Eye Res."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib101","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/j.neuron.2021.02.009","article-title":"SARM1 is a metabolic sensor activated by an increased NMN\/NAD","volume":"109","author":"Figley","year":"2021","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib102","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23031606","article-title":"SARM1 ablation is protective and preserves spatial vision in an in vivo mouse model of retinal ganglion cell degeneration","volume":"23","author":"Finnegan","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"Pt 1","key":"10.1016\/j.mam.2023.101193_bib103","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1093\/brain\/awn269","article-title":"Visual system involvement in patients with Friedreich's ataxia","volume":"132","author":"Fortuna","year":"2009","journal-title":"Brain"},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib104","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1089\/jop.2011.0062","article-title":"Plasma citrate levels as a potential biomarker for glaucoma","volume":"27","author":"Fraenkl","year":"2011","journal-title":"J. Ocul. Pharmacol. Therapeut."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib105","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s40263-013-0076-8","article-title":"Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence","volume":"27","author":"Freiherr","year":"2013","journal-title":"CNS Drugs"},{"key":"10.1016\/j.mam.2023.101193_bib106","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.preteyeres.2018.04.001","article-title":"The coma in glaucoma: retinal ganglion cell dysfunction and recovery","volume":"65","author":"Fry","year":"2018","journal-title":"Prog. Retin. Eye Res."},{"issue":"9","key":"10.1016\/j.mam.2023.101193_bib107","first-page":"838","article-title":"Axoplasmic flow during chronic experimental glaucoma. 1. Light and electron microscopic studies of the monkey optic nervehead during development of glaucomatous cupping","volume":"17","author":"Gaasterland","year":"1978","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"13","key":"10.1016\/j.mam.2023.101193_bib108","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.15252\/embj.201796697","article-title":"Molecular definitions of autophagy and related processes","volume":"36","author":"Galluzzi","year":"2017","journal-title":"EMBO J."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib109","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1523\/JNEUROSCI.0872-18.2018","article-title":"Optogenetic stimulation of the superior colliculus confers retinal neuroprotection in a mouse glaucoma model","volume":"39","author":"Geeraerts","year":"2019","journal-title":"J. Neurosci."},{"issue":"6233","key":"10.1016\/j.mam.2023.101193_bib110","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1126\/science.1258366","article-title":"SARM1 activation triggers axon degeneration locally via NAD\u207a destruction","volume":"348","author":"Gerdts","year":"2015","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib111","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s12035-012-8339-9","article-title":"Insulin in the brain: sources, localization and functions","volume":"47","author":"Ghasemi","year":"2013","journal-title":"Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib112","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1000300","article-title":"Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons","volume":"8","author":"Gilley","year":"2010","journal-title":"PLoS Biol."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib113","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1093\/hmg\/ddy356","article-title":"Low levels of NMNAT2 compromise axon development and survival","volume":"28","author":"Gilley","year":"2019","journal-title":"Hum. Mol. Genet."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib114","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1016\/j.celrep.2015.02.060","article-title":"Absence of SARM1 rescues development and survival of NMNAT2-deficient axons","volume":"10","author":"Gilley","year":"2015","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib115","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.celrep.2017.09.027","article-title":"Sarm1 deletion, but not wld","volume":"21","author":"Gilley","year":"2017","journal-title":"Cell Rep."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib116","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1083\/jcb.200601067","article-title":"Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent","volume":"173","author":"Glater","year":"2006","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.mam.2023.101193_bib117","doi-asserted-by":"crossref","first-page":"5245","DOI":"10.1038\/ncomms6245","article-title":"Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations","volume":"5","author":"Godena","year":"2014","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib118","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0057557","article-title":"Enhanced insight into the autoimmune component of glaucoma: IgG autoantibody accumulation and pro-inflammatory conditions in human glaucomatous retina","volume":"8","author":"Gramlich","year":"2013","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib119","doi-asserted-by":"crossref","first-page":"672","DOI":"10.2174\/092986710790416263","article-title":"Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials","volume":"17","author":"Granchi","year":"2010","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.mam.2023.101193_bib120","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2020.556175","article-title":"Anterograde axonal transport in neuronal homeostasis and disease","volume":"13","author":"Guillaud","year":"2020","journal-title":"Front. Mol. Neurosci."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib121","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/s41467-017-00911-y","article-title":"HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients","volume":"8","author":"Guo","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mam.2023.101193_bib122","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.semcdb.2019.07.010","article-title":"Axonal transport defects and neurodegeneration: molecular mechanisms and therapeutic implications","volume":"99","author":"Guo","year":"2020","journal-title":"Semin. Cell Dev. Biol."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib123","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.107776","article-title":"Neurotoxic reactive astrocytes drive neuronal death after retinal injury","volume":"31","author":"Guttenplan","year":"2020","journal-title":"Cell Rep."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib124","doi-asserted-by":"crossref","first-page":"219","DOI":"10.3341\/kjo.2005.19.3.219","article-title":"Neuroprotective effect of citicoline on retinal cell damage induced by kainic acid in rats","volume":"19","author":"Han","year":"2005","journal-title":"Kor. J. Ophthalmol."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib125","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0092-8674(02)00833-4","article-title":"Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action","volume":"110","author":"Hara","year":"2002","journal-title":"Cell"},{"issue":"19","key":"10.1016\/j.mam.2023.101193_bib126","doi-asserted-by":"crossref","first-page":"E3839","DOI":"10.1073\/pnas.1608769114","article-title":"Early immune responses are independent of RGC dysfunction in glaucoma with complement component C3 being protective","volume":"114","author":"Harder","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mam.2023.101193_bib127","series-title":"Disturbed Glucose and Pyruvate Metabolism in Glaucoma with Neuroprotection by Pyruvate or Rapamycin","author":"Harder","year":"2020"},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib128","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.neuron.2012.08.019","article-title":"Synaptic energy use and supply","volume":"75","author":"Harris","year":"2012","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib129","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1186\/s12974-018-1346-7","article-title":"Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma","volume":"15","author":"Harun-Or-Rashid","year":"2018","journal-title":"J. Neuroinflammation"},{"issue":"22","key":"10.1016\/j.mam.2023.101193_bib130","doi-asserted-by":"crossref","first-page":"5122","DOI":"10.1523\/JNEUROSCI.3652-17.2018","article-title":"Structural and functional rescue of chronic metabolically stressed optic nerves through respiration","volume":"38","author":"Harun-Or-Rashid","year":"2018","journal-title":"J. Neurosci."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib131","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/jnr.490220405","article-title":"Glucose transport in primary cultured neurons","volume":"22","author":"Heidenrich","year":"1989","journal-title":"J. Neurosci. Res."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib132","doi-asserted-by":"crossref","first-page":"506","DOI":"10.4103\/1673-5374.293145","article-title":"Dysfunction of axonal transport in normal-tension glaucoma: a biomarker of disease progression and a potential therapeutic target","volume":"16","author":"Hirooka","year":"2021","journal-title":"Neural Regen. Res."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib133","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0053830","article-title":"Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis","volume":"8","author":"Holliday","year":"2013","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib134","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1083\/jcb.200706181","article-title":"Axons of retinal ganglion cells are insulted in the optic nerve early in DBA\/2J glaucoma","volume":"179","author":"Howell","year":"2007","journal-title":"JCB (J. Cell Biol.)"},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib135","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1172\/JCI44646","article-title":"Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma","volume":"121","author":"Howell","year":"2011","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.mam.2023.101193_bib136","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.expneurol.2012.01.014","article-title":"Intrinsic axonal degeneration pathways are critical for glaucomatous damage","volume":"246","author":"Howell","year":"2013","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.mam.2023.101193_bib137","doi-asserted-by":"crossref","DOI":"10.1186\/1742-2094-10-76","article-title":"Deficiency of complement component 5 ameliorates glaucoma in DBA\/2J mice","volume":"10","author":"Howell","year":"2013","journal-title":"J. Neuroinflammation"},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib138","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1172\/JCI61135","article-title":"Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma","volume":"122","author":"Howell","year":"2012","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib139","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1186\/s12974-021-02366-x","article-title":"Interplay between M\u00fcller cells and microglia aggravates retinal inflammatory response in experimental glaucoma","volume":"18","author":"Hu","year":"2021","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.mam.2023.101193_bib140","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108460","article-title":"Increased ratios of complement factors C3a to C3 in aqueous humor and serum mark glaucoma progression","volume":"204","author":"Hubens","year":"2021","journal-title":"Exp. Eye Res."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib141","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jss.2006.07.034","article-title":"Screening and detection of apoptosis","volume":"139","author":"Huerta","year":"2007","journal-title":"J. Surg. Res."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib142","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1111\/ceo.13818","article-title":"Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: a crossover randomized clinical trial","volume":"48","author":"Hui","year":"2020","journal-title":"Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.mam.2023.101193_bib143","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3389\/fnins.2017.00146","article-title":"Metabolic vulnerability in the neurodegenerative disease glaucoma","volume":"11","author":"Inman","year":"2017","journal-title":"Front. Neurosci."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib144","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1111\/j.1460-9568.1997.tb01534.x","article-title":"Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat","volume":"9","author":"Isenmann","year":"1997","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.mam.2023.101193_bib145","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.mito.2017.08.014","article-title":"Mitochondrial dynamics, transport, and quality control: a bottleneck for retinal ganglion cell viability in optic neuropathies","volume":"36","author":"Ito","year":"2017","journal-title":"Mitochondrion"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib146","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0014567","article-title":"Mitochondrial damage in the trabecular meshwork occurs only in primary open-angle glaucoma and in pseudoexfoliative glaucoma","volume":"6","author":"Izzotti","year":"2011","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib147","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1038\/ncb1183","article-title":"Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive","volume":"6","author":"Jacinto","year":"2004","journal-title":"Nat. Cell Biol."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib148","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1083\/jcb.200506099","article-title":"Retinal ganglion cell degeneration is topological but not cell type specific in DBA\/2J mice","volume":"171","author":"Jakobs","year":"2005","journal-title":"JCB (J. Cell Biol.)"},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib149","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1167\/iovs.13-12968","article-title":"Mitochondrial DNA variant discovery in normal-tension glaucoma patients by next-generation sequencing","volume":"55","author":"Jeoung","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mam.2023.101193_bib150","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jbior.2019.03.003","article-title":"Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship","volume":"72","author":"Jhanwar-Uniyal","year":"2019","journal-title":"Adv. Biol. Regul."},{"key":"10.1016\/j.mam.2023.101193_bib151","doi-asserted-by":"crossref","DOI":"10.1016\/j.ceca.2022.102588","article-title":"TRPV4 and TRPC1 channels mediate the response to tensile strain in mouse M\u00fcller cells","volume":"104","author":"Jo","year":"2022","journal-title":"Cell Calcium"},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib152","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1080\/02713680701375183","article-title":"Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor","volume":"32","author":"Joachim","year":"2007","journal-title":"Curr. Eye Res."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib153","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1167\/iovs.14-15094","article-title":"Radiation pretreatment does not protect the rat optic nerve from elevated intraocular pressure-induced injury","volume":"56","author":"Johnson","year":"2015","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mam.2023.101193_bib154","first-page":"1331","article-title":"Increased optic atrophy type 1 expression protects retinal ganglion cells in a mouse model of glaucoma","volume":"16","author":"Ju","year":"2010","journal-title":"Mol. Vis."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib155","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1186\/s12974-018-1365-4","article-title":"Monocyte infiltration rather than microglia proliferation dominates the early immune response to rapid photoreceptor degeneration","volume":"15","author":"Karlen","year":"2018","journal-title":"J. Neuroinflammation"},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib156","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/s41580-018-0001-6","article-title":"The coming of age of chaperone-mediated autophagy","volume":"19","author":"Kaushik","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib157","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1001\/archopht.1997.01100160201010","article-title":"TUNEL-positive ganglion cells in human primary open-angle glaucoma","volume":"115","author":"Kerrigan","year":"1997","journal-title":"Arch. Ophthalmol."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib158","first-page":"741","article-title":"Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons","volume":"41","author":"Kerrigan-Baumrind","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"14","key":"10.1016\/j.mam.2023.101193_bib159","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abd2590","article-title":"Receptor-ligand supplementation via a self-cleaving 2A peptide-based gene therapy promotes CNS axonal transport with functional recovery","volume":"7","author":"Khatib","year":"2021","journal-title":"Sci. Adv."},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib160","doi-asserted-by":"crossref","first-page":"5046","DOI":"10.1167\/iovs.16-20017","article-title":"Assessing the association of mitochondrial genetic variation with primary open-angle glaucoma using gene-set analyses","volume":"57","author":"Khawaja","year":"2016","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib161","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1038\/s41588-018-0126-8","article-title":"Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma","volume":"50","author":"Khawaja","year":"2018","journal-title":"Nat. Genet."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib162","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S1097-2765(03)00114-X","article-title":"GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR","volume":"11","author":"Kim","year":"2003","journal-title":"Mol. Cell"},{"issue":"1\u20132","key":"10.1016\/j.mam.2023.101193_bib163","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.brainres.2005.07.005","article-title":"Retinal ganglion cell death is delayed by activation of retinal intrinsic cell survival program","volume":"1057","author":"Kim","year":"2005","journal-title":"Brain Res."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib164","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0268541","article-title":"Aquaporin 4 is not present in normal porcine and human lamina cribrosa","volume":"17","author":"Kimball","year":"2022","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib165","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3233\/JAD-2010-080785","article-title":"Visual impairment in Alzheimer's disease: a critical review","volume":"21","author":"Kirby","year":"2010","journal-title":"J. Alzheimers Dis."},{"issue":"10","key":"10.1016\/j.mam.2023.101193_bib166","doi-asserted-by":"crossref","first-page":"e860","DOI":"10.1038\/cddis.2013.391","article-title":"Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration","volume":"4","author":"Kitaoka","year":"2013","journal-title":"Cell Death Dis."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib167","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1755-3768.1983.tb01424.x","article-title":"Histopathology of eye, optic nerve and brain in a case of dominant optic atrophy","volume":"61","author":"Kjer","year":"1983","journal-title":"Acta Ophthalmol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib168","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1086\/301901","article-title":"Genetic association of apolipoprotein E with age-related macular degeneration","volume":"63","author":"Klaver","year":"1998","journal-title":"Am. J. Hum. Genet."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib169","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.201912047","article-title":"SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration","volume":"219","author":"Ko","year":"2020","journal-title":"J. Cell Biol."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib170","first-page":"59","article-title":"Importance of m\u00fcller cells","volume":"5","author":"Kobat","year":"2020","journal-title":"Beyoglu Eye J"},{"key":"10.1016\/j.mam.2023.101193_bib171","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2147\/OPTH.S155168","article-title":"Elevated levels of plasma tumor necrosis factor alpha in patients with pseudoexfoliation glaucoma","volume":"12","author":"Kondkar","year":"2018","journal-title":"Clin. Ophthalmol."},{"key":"10.1016\/j.mam.2023.101193_bib172","doi-asserted-by":"crossref","first-page":"701","DOI":"10.2147\/OPTH.S162999","article-title":"Association of increased levels of plasma tumor necrosis factor alpha with primary open-angle glaucoma","volume":"12","author":"Kondkar","year":"2018","journal-title":"Clin. Ophthalmol."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib173","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1167\/iovs.19-27099","article-title":"Nicotinamide deficiency in primary open-angle glaucoma","volume":"60","author":"Kouassi Nzoughet","year":"2019","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib174","doi-asserted-by":"crossref","first-page":"4626","DOI":"10.4049\/jimmunol.1601488","article-title":"Overexpression of soluble fas ligand following adeno-associated virus gene therapy prevents retinal ganglion cell death in chronic and acute murine models of glaucoma","volume":"197","author":"Krishnan","year":"2016","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib175","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1186\/s12974-019-1576-3","article-title":"A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma","volume":"16","author":"Krishnan","year":"2019","journal-title":"J. Neuroinflammation"},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib176","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3109\/02713683.2013.836541","article-title":"From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma","volume":"39","author":"Kri\u017eaj","year":"2014","journal-title":"Curr. Eye Res."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib177","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.exer.2006.03.002","article-title":"Retinal synthesis and deposition of complement components induced by ocular hypertension","volume":"83","author":"Kuehn","year":"2006","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.mam.2023.101193_bib178","first-page":"220","volume":"vol. 19","author":"Kumar","year":"2013"},{"key":"10.1016\/j.mam.2023.101193_bib179","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3389\/fnins.2017.00045","article-title":"Oral delivery of a synthetic sterol reduces axonopathy and inflammation in a rodent model of glaucoma","volume":"11","author":"Lambert","year":"2017","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.mam.2023.101193_bib180","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.3389\/fphar.2019.01117","article-title":"Morphological and functional evaluation of oral citicoline therapy in chronic open-angle glaucoma patients: a pilot study with a 2-year follow-up","volume":"10","author":"Lanza","year":"2019","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib181","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1167\/iovs.13-12564","article-title":"Coenzyme Q10 inhibits glutamate excitotoxicity and oxidative stress-mediated mitochondrial alteration in a mouse model of glaucoma","volume":"55","author":"Lee","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib182","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1167\/iovs.12-9596","article-title":"Impaired complex-I-linked respiration and ATP synthesis in primary open-angle glaucoma patient lymphoblasts","volume":"53","author":"Lee","year":"2012","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib183","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.exer.2010.07.015","article-title":"Mitochondrial dysfunction in glaucoma and emerging bioenergetic therapies","volume":"93","author":"Lee","year":"2011","journal-title":"Exp. Eye Res."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib184","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1001\/archopht.124.4.520","article-title":"Minocycline delays death of retinal ganglion cells in experimental glaucoma and after optic nerve transection","volume":"124","author":"Levkovitch-Verbin","year":"2006","journal-title":"Arch. Ophthalmol."},{"issue":"9","key":"10.1016\/j.mam.2023.101193_bib185","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1097\/IJG.0000000000001014","article-title":"Decreased serum levels of complement C3 reflect complement system dysregulation in patients with primary open-angle glaucoma: results from a pilot study","volume":"27","author":"Li","year":"2018","journal-title":"J. Glaucoma"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib186","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1371\/journal.pgen.0010004","article-title":"Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage","volume":"1","author":"Libby","year":"2005","journal-title":"PLoS Genet."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib187","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/s41580-019-0199-y","article-title":"mTOR at the nexus of nutrition, growth, ageing and disease","volume":"21","author":"Liu","year":"2020","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib188","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1002\/cne.22016","article-title":"Regulation of neonatal development of retinal ganglion cell dendrites by neurotrophin-3 overexpression","volume":"514","author":"Liu","year":"2009","journal-title":"J. Comp. Neurol."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib189","doi-asserted-by":"crossref","first-page":"355","DOI":"10.2478\/s13380-012-0044-7","article-title":"Pathologies of axonal transport in neurodegenerative diseases","volume":"3","author":"Liu","year":"2012","journal-title":"Transl. Neurosci."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib190","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s00441-013-1584-z","article-title":"Challenges in the development of glaucoma neuroprotection therapy","volume":"353","author":"Liu","year":"2013","journal-title":"Cell Tissue Res."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib191","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1084\/jem.20101202","article-title":"Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages","volume":"208","author":"London","year":"2011","journal-title":"J. Exp. Med."},{"issue":"18","key":"10.1016\/j.mam.2023.101193_bib192","doi-asserted-by":"crossref","first-page":"3464","DOI":"10.1111\/bph.14554","article-title":"Amyloid precursor protein-mediated mitochondrial regulation and Alzheimer's disease","volume":"176","author":"Lopez Sanchez","year":"2019","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib193","doi-asserted-by":"crossref","first-page":"9835","DOI":"10.1038\/s41598-017-10233-0","article-title":"Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta","volume":"7","author":"Lopez Sanchez","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mam.2023.101193_bib194","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.72823","article-title":"'Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1'","volume":"10","author":"Loreto","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.mam.2023.101193_bib195","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2019.104678","article-title":"Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration","volume":"134","author":"Loreto","year":"2020","journal-title":"Neurobiol. Dis."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib196","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.fct.2008.10.029","article-title":"Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells","volume":"47","author":"Luna","year":"2009","journal-title":"Food Chem. Toxicol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib197","doi-asserted-by":"crossref","first-page":"4845","DOI":"10.1038\/s41467-018-07295-7","article-title":"Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells","volume":"9","author":"Lund","year":"2018","journal-title":"Nat. Commun."},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib198","doi-asserted-by":"crossref","first-page":"5697","DOI":"10.1167\/iovs.10-5407","article-title":"Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling","volume":"51","author":"Luo","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib199","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/nn770","article-title":"Wallerian degeneration of injured axons and synapses is delayed by a Ube4b\/Nmnat chimeric gene","volume":"4","author":"Mack","year":"2001","journal-title":"Nat. Neurosci."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib200","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s13024-020-00400-9","article-title":"CNS axonal degeneration and transport deficits at the optic nerve head precede structural and functional loss of retinal ganglion cells in a mouse model of glaucoma","volume":"15","author":"Maddineni","year":"2020","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.mam.2023.101193_bib201","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2017.01.002","article-title":"BAX to basics: how the BCL2 gene family controls the death of retinal ganglion cells","volume":"57","author":"Maes","year":"2017","journal-title":"Prog. Retin. Eye Res."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib202","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23052591","article-title":"Damage-associated molecular patterns (DAMPs) in retinal disorders","volume":"23","author":"Mahaling","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.mam.2023.101193_bib203","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1038\/nrm2239","article-title":"Self-eating and self-killing: crosstalk between autophagy and apoptosis","volume":"8","author":"Maiuri","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.mam.2023.101193_bib204","article-title":"INVIVO effects of brain-derived neurotrophic factor (BDNF) and injury on the survival of axotomized retinal ganglion-cells (rgcs) in adult-rats","volume":"3","author":"Mansour-Robaey","year":"1992","journal-title":"Mol. Biol. Cell"},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib205","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19072043","article-title":"Role of mTOR in glucose and lipid metabolism","volume":"19","author":"Mao","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib206","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.1007\/s00417-018-4081-y","article-title":"CD163+ macrophages infiltrate axon bundles of postmortem optic nerves with glaucoma","volume":"256","author":"Margeta","year":"2018","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib207","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nrm3735","article-title":"Self-consumption: the interplay of autophagy and apoptosis","volume":"15","author":"Mari\u00f1o","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib208","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.neuron.2012.10.002","article-title":"The neuronal organization of the retina","volume":"76","author":"Masland","year":"2012","journal-title":"Neuron"},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib209","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/0896-6273(95)90172-8","article-title":"Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture","volume":"15","author":"Meyer-Franke","year":"1995","journal-title":"Neuron"},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib210","doi-asserted-by":"crossref","first-page":"133","DOI":"10.4161\/bioa.27049","article-title":"Axonal trafficking of NMNAT2 and its roles in axon growth and survival in vivo","volume":"3","author":"Milde","year":"2013","journal-title":"BioArchitecture"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib211","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-12858-7","article-title":"Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes","volume":"7","author":"Mirzaei","year":"2017","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib212","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1111\/bph.16062","article-title":"Mitophagy: a promising therapeutic target for neuroprotection during ageing and age-related diseases","volume":"180","author":"Mishra","year":"2023","journal-title":"Br. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib213","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1442-9071.2012.02789.x","article-title":"Retina ganglion cell degeneration in glaucoma: an opportunity missed? A review","volume":"40","author":"Morgan","year":"2012","journal-title":"Clin. Exp. Ophthalmol."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib214","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1038\/cdd.2014.149","article-title":"REDD2-mediated inhibition of mTOR promotes dendrite retraction induced by axonal injury","volume":"22","author":"Morquette","year":"2015","journal-title":"Cell Death Differ."},{"issue":"5337","key":"10.1016\/j.mam.2023.101193_bib215","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1126\/science.278.5337.412","article-title":"Life and death of neurons in the aging brain","volume":"278","author":"Morrison","year":"1997","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib216","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1001\/archopht.117.8.1050","article-title":"Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma","volume":"117","author":"Neufeld","year":"1999","journal-title":"Arch. Ophthalmol."},{"issue":"35","key":"10.1016\/j.mam.2023.101193_bib217","doi-asserted-by":"crossref","first-page":"E3631","DOI":"10.1073\/pnas.1402449111","article-title":"Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease","volume":"111","author":"Nguyen","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mam.2023.101193_bib218","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1146\/annurev.neuro.051508.135728","article-title":"Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy","volume":"35","author":"Nickells","year":"2012","journal-title":"Annu. Rev. Neurosci."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib219","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/eye.2011.291","article-title":"Ophthalmic features of Friedreich ataxia","volume":"26","author":"Noval","year":"2012","journal-title":"Eye"},{"key":"10.1016\/j.mam.2023.101193_bib220","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0074-7742(07)82022-8","article-title":"Retinal damage caused by high intraocular pressure-induced transient ischemia is prevented by coenzyme Q10 in rat","volume":"82","author":"Nucci","year":"2007","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.mam.2023.101193_bib221","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.exer.2015.06.006","article-title":"Assessment of retinal ganglion cell damage in glaucomatous optic neuropathy: axon transport, injury and soma loss","volume":"141","author":"Nuschke","year":"2015","journal-title":"Exp. Eye Res."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib222","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.immuni.2019.02.007","article-title":"Microglial function is distinct in different anatomical locations during retinal homeostasis and degeneration","volume":"50","author":"O'Koren","year":"2019","journal-title":"Immunity"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib223","doi-asserted-by":"crossref","DOI":"10.3390\/ph14030281","article-title":"Citicoline in ophthalmological neurodegenerative disease: a comprehensive review","volume":"14","author":"Oddone","year":"2021","journal-title":"Pharmaceuticals"},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib224","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/hmg\/ddt485","article-title":"DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking","volume":"23","author":"Ogawa","year":"2014","journal-title":"Hum. Mol. Genet."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib225","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/jcp.20950","article-title":"Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis","volume":"211","author":"Olichon","year":"2007","journal-title":"J. Cell. Physiol."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib226","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s004170100309","article-title":"Leber's hereditary optic neuropathy mitochondrial DNA mutations in normal-tension glaucoma","volume":"239","author":"Opial","year":"2001","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"issue":"10","key":"10.1016\/j.mam.2023.101193_bib227","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1038\/s41419-018-1041-8","article-title":"Neuroprotection of retinal ganglion cells by a novel gene therapy construct that achieves sustained enhancement of brain-derived neurotrophic factor\/tropomyosin-related kinase receptor-B signaling","volume":"9","author":"Osborne","year":"2018","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.mam.2023.101193_bib228","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.ejphar.2016.04.032","article-title":"Glaucoma: focus on mitochondria in relation to pathogenesis and neuroprotection","volume":"787","author":"Osborne","year":"2016","journal-title":"Eur. J. Pharmacol."},{"issue":"16","key":"10.1016\/j.mam.2023.101193_bib229","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1097\/00001756-200211150-00023","article-title":"Citicoline has a protective effect on damaged retinal ganglion cells in mouse culture retina","volume":"13","author":"Oshitari","year":"2002","journal-title":"Neuroreport"},{"issue":"21","key":"10.1016\/j.mam.2023.101193_bib230","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1016\/j.neuron.2022.10.020","article-title":"Microglia states and nomenclature: a field at its crossroads","volume":"110","author":"Paolicelli","year":"2022","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib231","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s10633-005-7348-7","article-title":"Electrophysiological assessment of glaucomatous visual dysfunction during treatment with cytidine-5'-diphosphocholine (citicoline): a study of 8 years of follow-up","volume":"110","author":"Parisi","year":"2005","journal-title":"Doc. Ophthalmol."},{"key":"10.1016\/j.mam.2023.101193_bib232","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0079-6123(08)01137-0","article-title":"Evidence of the neuroprotective role of citicoline in glaucoma patients","volume":"173","author":"Parisi","year":"2008","journal-title":"Prog. Brain Res."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib233","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.exer.2005.02.007","article-title":"Neuroprotective effect of citicoline against KA-induced neurotoxicity in the rat retina","volume":"81","author":"Park","year":"2005","journal-title":"Exp. Eye Res."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib234","doi-asserted-by":"crossref","first-page":"e290","DOI":"10.1038\/cddis.2012.26","article-title":"Activation of autophagy induces retinal ganglion cell death in a chronic hypertensive glaucoma model","volume":"3","author":"Park","year":"2012","journal-title":"Cell Death Dis."},{"issue":"5903","key":"10.1016\/j.mam.2023.101193_bib235","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1126\/science.1161566","article-title":"Promoting axon regeneration in the adult CNS by modulation of the PTEN\/mTOR pathway","volume":"322","author":"Park","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.mam.2023.101193_bib236","series-title":"Ocular Manifestations of Alzheimer's Disease in Animal Models","author":"Parnell","year":"2012"},{"issue":"47","key":"10.1016\/j.mam.2023.101193_bib237","doi-asserted-by":"crossref","first-page":"11851","DOI":"10.1523\/JNEUROSCI.1700-16.2016","article-title":"Novel roles for the insulin-regulated glucose transporter-4 in hippocampally dependent memory","volume":"36","author":"Pearson-Leary","year":"2016","journal-title":"J. Neurosci."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib238","first-page":"764","article-title":"Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma","volume":"41","author":"Pease","year":"2000","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib239","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/aos.12203","article-title":"Factors associated with lifetime risk of open-angle glaucoma blindness","volume":"92","author":"Peters","year":"2014","journal-title":"Acta Ophthalmol."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib240","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1091\/mbc.e05-06-0526","article-title":"Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons","volume":"17","author":"Pilling","year":"2006","journal-title":"Mol. Biol. Cell"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib241","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3109\/02713683.2015.1004719","article-title":"Riluzole- and resveratrol-induced delay of retinal ganglion cell death in an experimental model of glaucoma","volume":"41","author":"Pirhan","year":"2016","journal-title":"Curr. Eye Res."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib242","first-page":"606","article-title":"The dynamics and location of axonal transport blockade by acute intraocular pressure elevation in primate optic nerve","volume":"15","author":"Quigley","year":"1976","journal-title":"Invest. Ophthalmol."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib243","first-page":"137","article-title":"Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport","volume":"19","author":"Quigley","year":"1980","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib244","first-page":"774","article-title":"Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis","volume":"36","author":"Quigley","year":"1995","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib245","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111324","article-title":"Restoration of mitochondria axonal transport by adaptor Disc1 supplementation prevents neurodegeneration and rescues visual function","volume":"40","author":"Quintero","year":"2022","journal-title":"Cell Rep."},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib246","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1001\/archopht.1981.03930010650010","article-title":"Rapid axonal transport in primate optic nerve. Distribution of pressure-induced interruption","volume":"99","author":"Radius","year":"1981","journal-title":"Arch. Ophthalmol."},{"issue":"5557","key":"10.1016\/j.mam.2023.101193_bib247","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1126\/science.1066901","article-title":"Adult-onset primary open-angle glaucoma caused by mutations in optineurin","volume":"295","author":"Rezaie","year":"2002","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib248","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1007\/s12035-021-02675-5","article-title":"Bax contributes to retinal ganglion cell dendritic degeneration during glaucoma","volume":"59","author":"Risner","year":"2022","journal-title":"Mol. Neurobiol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib249","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13024-021-00459-y","article-title":"Neuroprotection by wld","volume":"16","author":"Risner","year":"2021","journal-title":"Mol. Neurodegener."},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib250","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0050230","article-title":"Secondary post-geniculate involvement in Leber's hereditary optic neuropathy","volume":"7","author":"Rizzo","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib251","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/cdd.2011.88","article-title":"Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice","volume":"19","author":"Rodr\u00edguez-Muela","year":"2012","journal-title":"Cell Death Differ."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib252","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1111\/acel.12072","article-title":"Balance between autophagic pathways preserves retinal homeostasis","volume":"12","author":"Rodr\u00edguez-Muela","year":"2013","journal-title":"Aging Cell"},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib253","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0040065","article-title":"Etanercept, a widely used inhibitor of tumor necrosis factor-\u03b1 (TNF-\u03b1), prevents retinal ganglion cell loss in a rat model of glaucoma","volume":"7","author":"Roh","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib254","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s40478-022-01427-3","article-title":"Widespread retina and optic nerve neuroinflammation in enucleated eyes from glaucoma patients","volume":"10","author":"Rutigliani","year":"2022","journal-title":"Acta Neuropathol. Commun."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib255","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s11940-010-0100-y","article-title":"Leber's hereditary optic neuropathy","volume":"13","author":"Sadun","year":"2011","journal-title":"Curr. Treat. Options Neurol."},{"issue":"44","key":"10.1016\/j.mam.2023.101193_bib256","doi-asserted-by":"crossref","first-page":"16033","DOI":"10.1523\/JNEUROSCI.3580-11.2011","article-title":"Age-related alterations in neurons of the mouse retina","volume":"31","author":"Samuel","year":"2011","journal-title":"J. Neurosci."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib257","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S0008-6363(99)00384-3","article-title":"Morphologic and biochemical hallmarks of apoptosis","volume":"45","author":"Saraste","year":"2000","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.mam.2023.101193_bib258","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.62027","article-title":"'SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration'","volume":"9","author":"Sasaki","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.mam.2023.101193_bib259","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.19749","article-title":"'NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD'","volume":"5","author":"Sasaki","year":"2016","journal-title":"Elife"},{"key":"10.1016\/j.mam.2023.101193_bib260","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2021.113842","article-title":"'Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection'","volume":"345","author":"Sasaki","year":"2021","journal-title":"Exp. Neurol."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib261","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.cell.2017.02.004","article-title":"mTOR signaling in growth, metabolism, and disease","volume":"168","author":"Saxton","year":"2017","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib262","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.cell.2017.03.035","article-title":"mTOR signaling in growth, metabolism, and disease","volume":"169","author":"Saxton","year":"2017","journal-title":"Cell"},{"issue":"Pt 9","key":"10.1016\/j.mam.2023.101193_bib263","first-page":"2095","article-title":"The axonal transport of mitochondria","volume":"125","author":"Saxton","year":"2012","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.mam.2023.101193_bib264","series-title":"Endpoints for Clinical Trials in Ophthalmology","author":"Schmetterer","year":"2023"},{"issue":"17","key":"10.1016\/j.mam.2023.101193_bib265","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.246322","article-title":"Microautophagy - distinct molecular mechanisms handle cargoes of many sizes","volume":"133","author":"Schuck","year":"2020","journal-title":"J. Cell Sci."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib266","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/j.exer.2006.05.021","article-title":"Citicoline and lithium rescue retinal ganglion cells following partial optic nerve crush in the rat","volume":"83","author":"Schuettauf","year":"2006","journal-title":"Exp. Eye Res."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib267","doi-asserted-by":"crossref","DOI":"10.1042\/AN20100003","article-title":"A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death","volume":"2","author":"Semaan","year":"2010","journal-title":"ASN Neuro"},{"key":"10.1016\/j.mam.2023.101193_bib268","first-page":"11","article-title":"'Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration'","author":"Shah","year":"2022","journal-title":"Elife"},{"issue":"19","key":"10.1016\/j.mam.2023.101193_bib269","doi-asserted-by":"crossref","first-page":"5252","DOI":"10.1523\/JNEUROSCI.4599-15.2016","article-title":"Corticothalamic axons are essential for retinal ganglion cell axon targeting to the mouse dorsal lateral geniculate nucleus","volume":"36","author":"Shanks","year":"2016","journal-title":"J. Neurosci."},{"key":"10.1016\/j.mam.2023.101193_bib270","first-page":"383","volume":"vol. 105","author":"Shephard","year":"1991"},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib271","doi-asserted-by":"crossref","DOI":"10.3390\/cells10081973","article-title":"Immune responses in the glaucomatous retina: regulation and dynamics","volume":"10","author":"Shestopalov","year":"2021","journal-title":"Cells"},{"issue":"9","key":"10.1016\/j.mam.2023.101193_bib272","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1016\/j.molcel.2022.03.007","article-title":"Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules","volume":"82","author":"Shi","year":"2022","journal-title":"Mol. Cell"},{"key":"10.1016\/j.mam.2023.101193_bib273","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2022.101064","article-title":"The physiological and pathophysiological roles of the autophagy lysosomal system in the conventional aqueous humor outflow pathway: more than cellular clean up","volume":"90","author":"Shim","year":"2022","journal-title":"Prog. Retin. Eye Res."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib274","doi-asserted-by":"crossref","first-page":"3005","DOI":"10.1167\/iovs.02-0620","article-title":"Differential dendritic shrinkage of alpha and beta retinal ganglion cells in cats with chronic glaucoma","volume":"44","author":"Shou","year":"2003","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib275","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/s41580-018-0089-8","article-title":"Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins","volume":"20","author":"Singh","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib276","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1038\/s41582-019-0257-2","article-title":"Axonal transport and neurological disease","volume":"15","author":"Sleigh","year":"2019","journal-title":"Nat. Rev. Neurol."},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib277","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/35072063","article-title":"The genetics and pathology of oxidative phosphorylation","volume":"2","author":"Smeitink","year":"2001","journal-title":"Nat. Rev. Genet."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib278","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0421-22.2022","article-title":"Loss of retinogeniculate synaptic function in the DBA\/2J mouse model of glaucoma","volume":"9","author":"Smith","year":"2022","journal-title":"eNeuro"},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib279","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s11892-016-0815-6","article-title":"Presence and risk factors for glaucoma in patients with diabetes","volume":"16","author":"Song","year":"2016","journal-title":"Curr. Diabetes Rep."},{"key":"10.1016\/j.mam.2023.101193_bib280","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.neuroscience.2015.05.072","article-title":"Impairment of insulin receptor substrate 1 signaling by insulin resistance inhibits neurite outgrowth and aggravates neuronal cell death","volume":"301","author":"Song","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.mam.2023.101193_bib281","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.62021","article-title":"'Structural basis for SARM1 inhibition and activation under energetic stress'","volume":"9","author":"Sporny","year":"2020","journal-title":"Elife"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib282","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1167\/iovs.05-0830","article-title":"'Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes'","volume":"47","author":"Stasi","year":"2006","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib283","doi-asserted-by":"crossref","DOI":"10.3390\/cells10030633","article-title":"'Neurodegeneration, neuroprotection and regeneration in the zebrafish retina'","volume":"10","author":"Stella","year":"2021","journal-title":"Cells"},{"issue":"5","key":"10.1016\/j.mam.2023.101193_bib284","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108271","article-title":"'GLP-1 receptor agonist NLY01 reduces retinal inflammation and neuron death secondary to ocular hypertension'","volume":"33","author":"Sterling","year":"2020","journal-title":"Cell Rep."},{"issue":"17","key":"10.1016\/j.mam.2023.101193_bib285","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2019101997","article-title":"Microglial subtypes: diversity within the microglial community","volume":"38","author":"Stratoulias","year":"2019","journal-title":"EMBO J."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib286","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0099719","article-title":"Rapamycin is neuroprotective in a rat chronic hypertensive glaucoma model","volume":"9","author":"Su","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.mam.2023.101193_bib287","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/gim.2014.121","article-title":"Whole-mitochondrial genome sequencing in primary open-angle glaucoma using massively parallel sequencing identifies novel and known pathogenic variants","volume":"17","author":"Sundaresan","year":"2015","journal-title":"Genet. Med."},{"key":"10.1016\/j.mam.2023.101193_bib288","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2019.07.002","article-title":"Axon injury signaling and compartmentalized injury response in glaucoma","volume":"73","author":"Syc-Mazurek","year":"2019","journal-title":"Prog. Retin. Eye Res."},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib289","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1152\/physrev.00026.2020","article-title":"Regulation and metabolic functions of mTORC1 and mTORC2","volume":"101","author":"Szwed","year":"2021","journal-title":"Physiol. Rev."},{"issue":"33","key":"10.1016\/j.mam.2023.101193_bib290","doi-asserted-by":"crossref","first-page":"10515","DOI":"10.1073\/pnas.1509879112","article-title":"In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS","volume":"112","author":"Takihara","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mam.2023.101193_bib291","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2022.109273","article-title":"Microglia depletion exacerbates retinal ganglion cell loss in a mouse model of glaucoma","volume":"225","author":"Tan","year":"2022","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.mam.2023.101193_bib292","first-page":"518","volume":"vol. 16","author":"Tanwar","year":"2010"},{"key":"10.1016\/j.mam.2023.101193_bib293","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2021.100998","article-title":"Molecular regulation of neuroinflammation in glaucoma: current knowledge and the ongoing search for new treatment targets","volume":"87","author":"Tezel","year":"2022","journal-title":"Prog. Retin. Eye Res."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib294","first-page":"1787","article-title":"TNF-alpha and TNF-alpha receptor-1 in the retina of normal and glaucomatous eyes","volume":"42","author":"Tezel","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"10","key":"10.1016\/j.mam.2023.101193_bib295","doi-asserted-by":"crossref","first-page":"5071","DOI":"10.1167\/iovs.10-5289","article-title":"Oxidative stress and the regulation of complement activation in human glaucoma","volume":"51","author":"Tezel","year":"2010","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"11","key":"10.1016\/j.mam.2023.101193_bib296","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib297","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s40478-023-01513-0","article-title":"NAD salvage pathway machinery expression in normal and glaucomatous retina and optic nerve","volume":"11","author":"Tribble","year":"2023","journal-title":"Acta Neuropathol. Commun."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib298","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s13041-020-00603-7","article-title":"Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA\/2 J mice","volume":"13","author":"Tribble","year":"2020","journal-title":"Mol. Brain"},{"key":"10.1016\/j.mam.2023.101193_bib299","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.903436","article-title":"Valproic acid reduces neuroinflammation to provide retinal ganglion cell neuroprotection in the retina axotomy model","volume":"10","author":"Tribble","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib344","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1167\/tvst.10.1.22","article-title":"When Is a Control Not a Control? Reactive Microglia Occur Throughout the Control Contralateral Pathway of Retinal Ganglion Cell Projections in Experimental Glaucoma","volume":"10","author":"Tribble","year":"2021","journal-title":"Transl Vis Sci Technol"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib301","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1167\/tvst.10.1.21","article-title":"Retinal ganglion cell degeneration in a rat magnetic bead model of ocular hypertensive glaucoma","volume":"10","author":"Tribble","year":"2021","journal-title":"Transl Vis Sci Technol"},{"key":"10.1016\/j.mam.2023.101193_bib302","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2021.101988","article-title":"Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction","volume":"43","author":"Tribble","year":"2021","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib303","doi-asserted-by":"crossref","first-page":"fcz035","DOI":"10.1093\/braincomms\/fcz035","article-title":"Midget retinal ganglion cell dendritic and mitochondrial degeneration is an early feature of human glaucoma","volume":"1","author":"Tribble","year":"2019","journal-title":"Brain Commun."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib304","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.expneurol.2005.10.035","article-title":"Insulin regulates neuronal glucose uptake by promoting translocation of glucose transporter GLUT3","volume":"198","author":"Uemura","year":"2006","journal-title":"Exp. Neurol."},{"issue":"10","key":"10.1016\/j.mam.2023.101193_bib305","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0140919","article-title":"Measurement of systemic mitochondrial function in advanced primary open-angle glaucoma and leber hereditary optic neuropathy","volume":"10","author":"Van Bergen","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2023.101193_bib306","first-page":"2271","volume":"vol. 18","author":"van de Ven","year":"2012"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib307","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1097-0320(19980101)31:1<1::AID-CYTO1>3.0.CO;2-R","article-title":"Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure","volume":"31","author":"van Engeland","year":"1998","journal-title":"Cytometry"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib308","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.neuron.2012.11.027","article-title":"TRAK\/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites","volume":"77","author":"van Spronsen","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.mam.2023.101193_bib309","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2015.06.003","article-title":"Glia-neuron interactions in the mammalian retina","volume":"51","author":"Vecino","year":"2016","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.mam.2023.101193_bib310","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2021.101038","article-title":"New insights into the role of autophagy in retinal and eye diseases","volume":"82","author":"Villarejo-Zori","year":"2021","journal-title":"Mol. Aspect. Med."},{"issue":"189","key":"10.1016\/j.mam.2023.101193_bib311","first-page":"369","article-title":"Experiments on the section of the glosso-pharyngeal and hypoglossal nerves of the frog, and observations of the alterations produced thereby in the structure of their primitive fibres","volume":"76","author":"Waller","year":"1851","journal-title":"Edinb Med. Surg. J."},{"issue":"33","key":"10.1016\/j.mam.2023.101193_bib312","doi-asserted-by":"crossref","first-page":"10093","DOI":"10.1073\/pnas.1508337112","article-title":"Local axonal protection by WldS as revealed by conditional regulation of protein stability","volume":"112","author":"Wang","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib313","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1167\/iovs.02-0333","article-title":"Varicosities of intraretinal ganglion cell axons in human and nonhuman primates","volume":"44","author":"Wang","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib314","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1167\/iovs.07-1325","article-title":"BDNF preserves the dendritic morphology of alpha and beta ganglion cells in the cat retina after optic nerve injury","volume":"49","author":"Weber","year":"2008","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib315","first-page":"2304","article-title":"Morphology of single ganglion cells in the glaucomatous primate retina","volume":"39","author":"Weber","year":"1998","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib316","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1016\/j.ophtha.2018.06.017","article-title":"Oral memantine for the treatment of glaucoma: design and results of 2 randomized, placebo-controlled, phase 3 studies","volume":"125","author":"Weinreb","year":"2018","journal-title":"Ophthalmology"},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib317","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s12276-019-0298-z","article-title":"mTORC2 activation protects retinal ganglion cells via Akt signaling after autophagy induction in traumatic optic nerve injury","volume":"51","author":"Wen","year":"2019","journal-title":"Exp. Mol. Med."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib318","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.preteyeres.2005.04.004","article-title":"Glaucoma: thinking in new ways-a r\u00f4le for autonomous axonal self-destruction and other compartmentalised processes?","volume":"24","author":"Whitmore","year":"2005","journal-title":"Prog. Retin. Eye Res."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib319","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s12974-017-0868-8","article-title":"GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma","volume":"14","author":"Williams","year":"2017","journal-title":"J. Neuroinflammation"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib320","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13024-018-0303-3","article-title":"Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA\/2J glaucoma","volume":"14","author":"Williams","year":"2019","journal-title":"Mol. Neurodegener."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib321","doi-asserted-by":"crossref","DOI":"10.1080\/19420889.2017.1356956","article-title":"Nicotinamide treatment robustly protects from inherited mouse glaucoma","volume":"11","author":"Williams","year":"2018","journal-title":"Commun. Integr. Biol."},{"key":"10.1016\/j.mam.2023.101193_bib322","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2017.00232","article-title":"Nicotinamide and WLDS act together to prevent neurodegeneration in glaucoma","volume":"11","author":"Williams","year":"2017","journal-title":"Front. Neurosci."},{"issue":"6326","key":"10.1016\/j.mam.2023.101193_bib323","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1126\/science.aal0092","article-title":"Vitamin B-3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice","volume":"355","author":"Williams","year":"2017","journal-title":"Science"},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib324","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1097\/IJG.0000000000000767","article-title":"Glaucoma as a metabolic optic neuropathy: making the case for nicotinamide treatment in glaucoma","volume":"26","author":"Williams","year":"2017","journal-title":"J. Glaucoma"},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib325","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0072282","article-title":"Retinal ganglion cell dendritic atrophy in DBA\/2J glaucoma","volume":"8","author":"Williams","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2023.101193_bib326","doi-asserted-by":"crossref","first-page":"2942","DOI":"10.1093\/brain\/awq218","article-title":"Opa1 deficiency in a mouse model of dominant optic atrophy leads to retinal ganglion cell dendropathy","volume":"133","author":"Williams","year":"2010","journal-title":"Brain"},{"key":"10.1016\/j.mam.2023.101193_bib327","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/brain\/awr330","article-title":"Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity","volume":"135","author":"Williams","year":"2012","journal-title":"Brain"},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib328","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/j.neurobiolaging.2013.01.006","article-title":"Retinal ganglion cell dendritic degeneration in a mouse model of Alzheimer's disease","volume":"34","author":"Williams","year":"2013","journal-title":"Neurobiol. Aging"},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib343","first-page":"1134","article-title":"Targeting NMNAT2 for neuroprotection in glaucoma","volume":"63","author":"Williams","year":"2022","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mam.2023.101193_bib329","doi-asserted-by":"crossref","DOI":"10.1186\/s13024-016-0091-6","article-title":"Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma","volume":"11","author":"Williams","year":"2016","journal-title":"Mol. Neurodegener."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib330","doi-asserted-by":"crossref","first-page":"124","DOI":"10.4161\/auto.23323","article-title":"The ULK1 complex: sensing nutrient signals for autophagy activation","volume":"9","author":"Wong","year":"2013","journal-title":"Autophagy"},{"issue":"3","key":"10.1016\/j.mam.2023.101193_bib331","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109872","article-title":"Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss","volume":"37","author":"Wu","year":"2021","journal-title":"Cell Rep."},{"issue":"8","key":"10.1016\/j.mam.2023.101193_bib332","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s12264-022-00833-w","article-title":"P2X7\/P2X4 receptors mediate proliferation and migration of retinal microglia in experimental glaucoma in mice","volume":"38","author":"Xu","year":"2022","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.mam.2023.101193_bib333","doi-asserted-by":"crossref","first-page":"5416","DOI":"10.1038\/ncomms6416","article-title":"The mTORC1 effectors S6K1 and 4E-BP play different roles in CNS axon regeneration","volume":"5","author":"Yang","year":"2014","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib334","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1186\/s12974-020-01930-1","article-title":"Transgenic inhibition of astroglial NF-\u03baB restrains the neuroinflammatory and neurodegenerative outcomes of experimental mouse glaucoma","volume":"17","author":"Yang","year":"2020","journal-title":"J. Neuroinflammation"},{"issue":"12","key":"10.1016\/j.mam.2023.101193_bib335","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1038\/s41419-021-04445-6","article-title":"CD82 protects against glaucomatous axonal transport deficits via mTORC1 activation in mice","volume":"12","author":"Ye","year":"2021","journal-title":"Cell Death Dis."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib336","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S1350-9462(00)00027-6","article-title":"Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease","volume":"20","author":"Yu","year":"2001","journal-title":"Prog. Retin. Eye Res."},{"issue":"2","key":"10.1016\/j.mam.2023.101193_bib337","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1136\/jmg.2009.067512","article-title":"OPA1 increases the risk of normal but not high tension glaucoma","volume":"47","author":"Yu-Wai-Man","year":"2010","journal-title":"J. Med. Genet."},{"issue":"6","key":"10.1016\/j.mam.2023.101193_bib338","doi-asserted-by":"crossref","DOI":"10.3390\/cells10061426","article-title":"Retinal ganglion cell transplantation: approaches for overcoming challenges to functional integration","volume":"10","author":"Zhang","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.mam.2023.101193_bib339","first-page":"234","volume":"vol. 207","author":"Zhang","year":"2018"},{"issue":"1","key":"10.1016\/j.mam.2023.101193_bib340","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1167\/iovs.12-10861","article-title":"Protection of mouse retinal ganglion cell axons and soma from glaucomatous and ischemic injury by cytoplasmic overexpression of Nmnat1","volume":"54","author":"Zhu","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.mam.2023.101193_bib341","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13578-020-00396-1","article-title":"mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges","volume":"10","author":"Zou","year":"2020","journal-title":"Cell Biosci."},{"issue":"7","key":"10.1016\/j.mam.2023.101193_bib342","doi-asserted-by":"crossref","first-page":"5097","DOI":"10.1167\/iovs.13-12157","article-title":"SIRT1 promotes RGC survival and delays loss of function following optic nerve crush","volume":"54","author":"Zuo","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."}],"container-title":["Molecular Aspects of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009829972300033X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009829972300033X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T18:20:33Z","timestamp":1758824433000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009829972300033X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":343,"alternative-id":["S009829972300033X"],"URL":"https:\/\/doi.org\/10.1016\/j.mam.2023.101193","relation":{},"ISSN":["0098-2997"],"issn-type":[{"value":"0098-2997","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuroprotection in glaucoma: Mechanisms beyond intraocular pressure lowering","name":"articletitle","label":"Article Title"},{"value":"Molecular Aspects of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mam.2023.101193","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101193"}}