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Nutr."},{"key":"10.1016\/j.mam.2026.101477_bib487","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.c5702","article-title":"Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials","volume":"341","author":"Sch\u00fcrks","year":"2010","journal-title":"BMJ"},{"key":"10.1016\/j.mam.2026.101477_bib488","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1186\/s12882-019-1585-6","article-title":"Vitamin e-loaded membrane dialyzers reduce hemodialysis inflammaging","volume":"20","author":"Sepe","year":"2019","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.mam.2026.101477_bib489","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1001\/jama.2008.600","article-title":"Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial","volume":"300","author":"Sesso","year":"2008","journal-title":"JAMA"},{"key":"10.1016\/j.mam.2026.101477_bib490","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/S1081-1206(10)61432-9","article-title":"Effect of vitamin E supplementation on the regular treatment of seasonal allergic rhinitis","volume":"92","author":"Shahar","year":"2004","journal-title":"Ann. 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