{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T05:05:25Z","timestamp":1789189525596,"version":"build-2803163510"},"reference-count":272,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["16\/01743-5"],"award-info":[{"award-number":["16\/01743-5"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["1252163"],"award-info":[{"award-number":["1252163"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009610","name":"Pontifical Catholic University of Chile","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009610","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Aspects of Medicine"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.mam.2026.101500","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T12:41:21Z","timestamp":1787143281000},"page":"101500","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Vascular dysfunction at the crossroads of gestational diabetes mellitus and cancer"],"prefix":"10.1016","volume":"111","author":[{"given":"Katherin","family":"Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Valero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Fuentes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Cornejo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Aravena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Zamora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Espinoza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"V\u00e1squez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Carlos","family":"Rivas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Vergara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilcia","family":"Sauceda-Acosta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Galaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garth L.","family":"Nicolson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo Ferreira","family":"de Mattos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5802-2243","authenticated-orcid":false,"given":"Luis","family":"Sobrevia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.mam.2026.101500_bib1","doi-asserted-by":"crossref","first-page":"3514","DOI":"10.3390\/ijms23073514","article-title":"Genomics and epigenomics of gestational diabetes mellitus: understanding the molecular pathways of the disease pathogenesis","volume":"23","author":"Abu Samra","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib2","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.toxrep.2020.08.002","article-title":"Placental microRNAs: responders to environmental chemicals and mediators of pathophysiology of the human placenta","volume":"7","author":"Addo","year":"2020","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.mam.2026.101500_bib3","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1080\/14767058.2016.1199676","article-title":"Placental vascularization and apoptosis in Type-1 and gestational DM","volume":"30","author":"Akarsu","year":"2017","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"10.1016\/j.mam.2026.101500_bib4","doi-asserted-by":"crossref","first-page":"440","DOI":"10.3390\/life15030440","article-title":"The hidden impact of gestational diabetes: unveiling offspring complications and long-term effects","volume":"15","author":"Al Bekai","year":"2025","journal-title":"Life"},{"key":"10.1016\/j.mam.2026.101500_bib5","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s40200-025-01633-5","article-title":"The association between gestational diabetes mellitus and cancer in women: an updated systematic review and meta-analysis","volume":"24","author":"Al-Jaf","year":"2025","journal-title":"J. Diabetes Metab. Disord."},{"key":"10.1016\/j.mam.2026.101500_bib6","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.3390\/cells9081914","article-title":"Decreased equilibrative nucleoside transporter 1 (ENT1) activity contributes to the high extracellular adenosine levels in mesenchymal glioblastoma stem-like cells","volume":"9","author":"Alarc\u00f3n","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.mam.2026.101500_bib7","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1038\/s41571-020-0382-2","article-title":"The adenosine pathway in immuno-oncology","volume":"17","author":"Allard","year":"2020","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.mam.2026.101500_bib8","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/imr.12528","article-title":"The ectonucleotidases CD39 and CD73: novel checkpoint inhibitor targets","volume":"276","author":"Allard","year":"2017","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.mam.2026.101500_bib9","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1158\/0008-5472.CAN-24-1875","article-title":"Adenosine uptake through the nucleoside transporter ENT1 suppresses antitumor immunity and T-cell pyrimidine synthesis","volume":"85","author":"Allard","year":"2025","journal-title":"Cancer Res."},{"key":"10.1016\/j.mam.2026.101500_bib10","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.2337\/dc25-S002","article-title":"2. Diagnosis and classification of diabetes: standards of care in diabetes\u20142025","volume":"48","year":"2025","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mam.2026.101500_bib11","doi-asserted-by":"crossref","first-page":"S321","DOI":"10.2337\/dc26-S015","article-title":"15. Management of diabetes in pregnancy: standards of care in diabetes-2026","volume":"49","year":"2026","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mam.2026.101500_bib12","doi-asserted-by":"crossref","first-page":"L1232","DOI":"10.1152\/ajplung.00109.2006","article-title":"TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia","volume":"291","author":"Angelini","year":"2006","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib13","doi-asserted-by":"crossref","first-page":"699","DOI":"10.3389\/fphys.2019.00699","article-title":"HIF-1\u03b1 stabilization increases miR-210 eliciting first trimester extravillous trophoblast mitochondrial dysfunction","volume":"10","author":"Anton","year":"2019","journal-title":"Front. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib14","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1038\/nrc3613","article-title":"Immunity, inflammation and cancer: a leading role for adenosine","volume":"13","author":"Antonioli","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib15","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.molmed.2013.03.005","article-title":"CD39 and CD73 in immunity and inflammation","volume":"19","author":"Antonioli","year":"2013","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.mam.2026.101500_bib16","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.placenta.2016.05.003","article-title":"Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus","volume":"43","author":"Araos","year":"2016","journal-title":"Placenta"},{"key":"10.1016\/j.mam.2026.101500_bib17","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2017.1423170","article-title":"PD-L1 expression is regulated by both DNA methylation and NF-kB during EMT signaling in non-small cell lung carcinoma","volume":"7","author":"Asgarova","year":"2018","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.mam.2026.101500_bib18","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2020-001586","article-title":"Placental proteome abnormalities in women with gestational diabetes and large-for-gestational-age newborns","volume":"8","author":"Assi","year":"2020","journal-title":"BMJ Open Diabetes Res. Care"},{"key":"10.1016\/j.mam.2026.101500_bib19","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1007\/s10555-024-10216-4","article-title":"Mitochondrial ribosomal proteins in metastasis and their potential use as prognostic and therapeutic targets","volume":"43","author":"Bacon","year":"2024","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/j.mam.2026.101500_bib20","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1161\/HYPERTENSIONAHA.119.12105","article-title":"Endothelin: 30 years from discovery to therapy","volume":"74","author":"Barton","year":"2019","journal-title":"Hypertension"},{"key":"10.1016\/j.mam.2026.101500_bib21","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1073\/pnas.0406092102","article-title":"Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis","volume":"102","author":"Bauer","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.mam.2026.101500_bib22","doi-asserted-by":"crossref","first-page":"R125","DOI":"10.1530\/ERC-11-0074","article-title":"Insulin receptor and cancer","volume":"18","author":"Belfiore","year":"2011","journal-title":"Endocr. Relat. Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib23","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1210\/er.2017-00073","article-title":"Insulin receptor isoforms in physiology and disease: an updated view","volume":"38","author":"Belfiore","year":"2017","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.mam.2026.101500_bib24","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1093\/ije\/dyab165","article-title":"Gestational diabetes and risk of breast cancer before age 55 years","volume":"50","author":"Bertrand","year":"2022","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.mam.2026.101500_bib25","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.bbadis.2016.11.010","article-title":"Mitochondrial dysfunction and oxidative stress in metabolic disorders - a step towards mitochondria based therapeutic strategies","volume":"1863","author":"Bhatti","year":"2017","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib26","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/678527","article-title":"Hypoxia strongly affects mitochondrial ribosomal proteins and translocases, as shown by quantitative proteomics of HeLa cells","volume":"2015","author":"Bousquet","year":"2015","journal-title":"Int. J. Proteomics"},{"key":"10.1016\/j.mam.2026.101500_bib27","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.cmet.2016.08.011","article-title":"LDHA-Associated lactic acid production blunts tumor immunosurveillance by T and NK cells","volume":"24","author":"Brand","year":"2016","journal-title":"Cell Metab."},{"key":"10.1016\/j.mam.2026.101500_bib28","doi-asserted-by":"crossref","first-page":"3446","DOI":"10.1002\/cncr.28864","article-title":"The MAPK pathway across different malignancies: a new perspective","volume":"120","author":"Burotto","year":"2014","journal-title":"Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib29","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2014.0066","article-title":"The placenta: a multifaceted, transient organ","volume":"370","author":"Burton","year":"2015","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib30","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.ajog.2025.07.039","article-title":"Formation of the placental membranes and pathophysiological origin of associated great obstetrical syndromes","volume":"233","author":"Burton","year":"2025","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.mam.2026.101500_bib31","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/S0002-9378(99)70518-1","article-title":"Maternal arterial connections to the placental intervillous space during the first trimester of human pregnancy: the Boyd collection revisited","volume":"181","author":"Burton","year":"1999","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.mam.2026.101500_bib32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.mam.2019.01.001","article-title":"Involvement of A2B adenosine receptors as anti-inflammatory in gestational diabesity","volume":"66","author":"Cabal\u00edn","year":"2019","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.mam.2026.101500_bib33","doi-asserted-by":"crossref","first-page":"10","DOI":"10.17925\/EE.2024.20.1.5","article-title":"The placental role in gestational diabetes mellitus: a molecular perspective","volume":"20","author":"Calvo","year":"2024","journal-title":"touchREV Endocrinol"},{"issue":"Suppl. A","key":"10.1016\/j.mam.2026.101500_bib34","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1053\/plac.2002.0815","article-title":"Adriana and Luisa Castellucci Award lecture 2001. Hypoxia inducible factor-1: oxygen regulation of trophoblast differentiation in normal and pre-eclamptic pregnancies--a review","volume":"23","author":"Caniggia","year":"2002","journal-title":"Placenta"},{"key":"10.1016\/j.mam.2026.101500_bib35","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.ccell.2016.10.006","article-title":"Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy","volume":"30","author":"Cantelmo","year":"2016","journal-title":"Cancer Cell"},{"key":"10.1016\/j.mam.2026.101500_bib36","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1097\/MOL.0b013e328328d0a4","article-title":"PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure","volume":"20","author":"Cant\u00f3","year":"2009","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.mam.2026.101500_bib37","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/nrc1713","article-title":"The role of disturbed pH dynamics and the Na+\/H+ exchanger in metastasis","volume":"5","author":"Cardone","year":"2005","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib38","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/nature10144","article-title":"Molecular mechanisms and clinical applications of angiogenesis","volume":"473","author":"Carmeliet","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.mam.2026.101500_bib39","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nrd3455","article-title":"Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases","volume":"10","author":"Carmeliet","year":"2011","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.mam.2026.101500_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/jcp.31243","article-title":"Nrf2 pre-recruitment at Enhancer 2 is a hallmark of H2O2-induced epigenetic transcriptional memory in the HMOX1 gene in human umbilical artery endothelial cells","volume":"239","author":"Carrasco-Wong","year":"2024","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2019.165535","article-title":"Placental structure in gestational diabetes mellitus","volume":"1866","author":"Carrasco-Wong","year":"2020","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib42","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.placenta.2017.01.120","article-title":"Intracellular acidification increases adenosine transport in human umbilical vein endothelial cells","volume":"51","author":"Celis","year":"2017","journal-title":"Placenta"},{"key":"10.1016\/j.mam.2026.101500_bib43","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1186\/s12885-019-5397-7","article-title":"Increased NHE1 expression is targeted by specific inhibitor cariporide to sensitize resistant breast cancer cells to doxorubicin in vitro and in vivo","volume":"19","author":"Chen","year":"2019","journal-title":"BMC Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib44","doi-asserted-by":"crossref","first-page":"3552","DOI":"10.3390\/ijms22073552","article-title":"The collagen-modifying enzyme PLOD2 is induced and required during L1-mediated colon cancer progression","volume":"22","author":"Cheriyamundath","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2018.12.005","article-title":"Oxidative stress: normal pregnancy versus preeclampsia","volume":"1866","author":"Chiarello","year":"2020","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib46","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.mam.2017.12.002","article-title":"Foetoplacental communication via extracellular vesicles in normal pregnancy and preeclampsia","volume":"60","author":"Chiarello","year":"2018","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.mam.2026.101500_bib47","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1152\/physrev.00028.2021","article-title":"Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs","volume":"103","author":"Cirino","year":"2023","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.mam.2026.101500_bib48","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/bph.17329","article-title":"miR-210 as a therapeutic target in diabetes-associated endothelial dysfunction","volume":"182","author":"Collado","year":"2025","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.mam.2026.101500_bib49","doi-asserted-by":"crossref","DOI":"10.1111\/apha.13671","article-title":"Gestational diabesity and foetoplacental vascular dysfunction","volume":"232","author":"Cornejo","year":"2021","journal-title":"Acta Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib50","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.cyto.2018.07.020","article-title":"Hyperglycemia induces inflammatory mediators in the human chorionic villous","volume":"111","author":"Corr\u00eaa-Silva","year":"2018","journal-title":"Cytokine"},{"key":"10.1016\/j.mam.2026.101500_bib51","doi-asserted-by":"crossref","first-page":"e39","DOI":"10.1161\/01.RES.0000215436.92414.1d","article-title":"Extracellular nucleotides and adenosine independently activate AMP-activated protein kinase in endothelial cells: involvement of P2 receptors and adenosine transporters","volume":"98","author":"da Silva","year":"2006","journal-title":"Circ. Res."},{"key":"10.1016\/j.mam.2026.101500_bib52","doi-asserted-by":"crossref","first-page":"633","DOI":"10.2147\/CLEP.S147188","article-title":"Maternal diabetes and incidence of childhood cancer - a nationwide cohort study and exploratory genetic analysis","volume":"9","author":"Deleskog","year":"2017","journal-title":"Clin. Epidemiol."},{"key":"10.1016\/j.mam.2026.101500_bib53","doi-asserted-by":"crossref","first-page":"S120","DOI":"10.2337\/dc07-s203","article-title":"The human placenta in gestational diabetes mellitus. The insulin and cytokine network","volume":"30","author":"Desoye","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mam.2026.101500_bib54","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.numecd.2014.06.005","article-title":"Features of endothelial dysfunction in umbilical cord vessels of women with gestational diabetes","volume":"24","author":"Di Fulvio","year":"2014","journal-title":"Nutr. Metabol. Cardiovasc. Dis."},{"key":"10.1016\/j.mam.2026.101500_bib55","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1146\/annurev-pathol-012513-104715","article-title":"MicroRNAs in cancer","volume":"9","author":"Di Leva","year":"2014","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.mam.2026.101500_bib56","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1080\/19336918.2015.1127467","article-title":"Post-transcriptional down regulation of ICAM-1 in feto-placental endothelium in GDM","volume":"10","author":"D\u00edaz-P\u00e9rez","year":"2016","journal-title":"Cell Adh. Migr."},{"key":"10.1016\/j.mam.2026.101500_bib57","doi-asserted-by":"crossref","first-page":"6186","DOI":"10.3390\/ijms24076186","article-title":"Circulating microRNA as biomarkers for gestational diabetes mellitus-A systematic review and meta-analysis","volume":"24","author":"Dinesen","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib58","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/jdi.12592","article-title":"Roles of p300 and cyclic adenosine monophosphate response element binding protein in high glucose-induced hypoxia-inducible factor 1\u03b1 inactivation under hypoxic conditions","volume":"8","author":"Ding","year":"2017","journal-title":"J. Diabetes Investig."},{"key":"10.1016\/j.mam.2026.101500_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2023.166834","article-title":"Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: a potential threat for programming cardiovascular disease","volume":"1869","author":"Diniz","year":"2023","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib60","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/aps.2012.143","article-title":"Negative regulation of mTOR activity by LKB1-AMPK signaling in non-small cell lung cancer cells","volume":"34","author":"Dong","year":"2013","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.mam.2026.101500_bib61","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s12958-025-01465-1","article-title":"Hydrogen sulfide in placental development and pregnancy disorders: mechanisms, therapeutic potential, and translational challenges","volume":"23","author":"Du","year":"2025","journal-title":"Reprod. Biol. Endocrinol. RBE"},{"key":"10.1016\/j.mam.2026.101500_bib62","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.canlet.2007.02.006","article-title":"Cellular responses to EGFR inhibitors and their relevance to cancer therapy","volume":"254","author":"Dutta","year":"2007","journal-title":"Cancer Lett."},{"key":"10.1016\/j.mam.2026.101500_bib63","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.freeradbiomed.2025.06.007","article-title":"Biomarkers of oxidative stress in maternal plasma, umbilical cord and placenta of patients with gestational diabetes: a systematic review and meta-analysis","volume":"237","author":"Etchegaray-Armijo","year":"2025","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.mam.2026.101500_bib64","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/cvr\/cvp410","article-title":"Nitric oxide reduces SLC29A1 promoter activity and adenosine transport involving transcription factor complex hCHOP\u2013C\/EBP\u03b1 in human umbilical vein endothelial cells from gestational diabetes","volume":"86","author":"Far\u00edas","year":"2010","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.mam.2026.101500_bib65","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/jcp.20680","article-title":"Nitric oxide reduces adenosine transporter ENT1 gene (SLC29A1) promoter activity in human fetal endothelium from gestational diabetes","volume":"208","author":"Far\u00edas","year":"2006","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib66","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.3390\/biomedicines11102660","article-title":"The regulation of endothelin-1 in pregnancies complicated by gestational diabetes: uncovering the vascular effects of insulin","volume":"11","author":"Fato","year":"2023","journal-title":"Biomedicines"},{"key":"10.1016\/j.mam.2026.101500_bib67","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.cmet.2012.12.001","article-title":"AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo","volume":"17","author":"Faubert","year":"2013","journal-title":"Cell Metab."},{"key":"10.1016\/j.mam.2026.101500_bib68","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.canlet.2014.01.018","article-title":"The AMP-activated protein kinase (AMPK) and cancer: many faces of a metabolic regulator","volume":"356","author":"Faubert","year":"2015","journal-title":"Cancer Lett."},{"key":"10.1016\/j.mam.2026.101500_bib69","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0157185","article-title":"Positive correlation between enhanced expression of TLR4\/MyD88\/NF-\u03baB with insulin resistance in placentae of gestational diabetes mellitus","volume":"11","author":"Feng","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2026.101500_bib70","doi-asserted-by":"crossref","first-page":"3812","DOI":"10.1182\/blood-2006-07-035972","article-title":"Inhibitory effect of tumor cell-derived lactic acid on human T cells","volume":"109","author":"Fischer","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.mam.2026.101500_bib71","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/1440-1681.13172","article-title":"Placental mitochondria and reactive oxygen species in the physiology and pathophysiology of pregnancy","volume":"47","author":"Fisher","year":"2020","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib72","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1158\/2159-8290.CD-19-0980","article-title":"Adenosine 2A receptor blockade as an immunotherapy for treatment-refractory renal cell cancer","volume":"10","author":"Fong","year":"2020","journal-title":"Cancer Discov."},{"key":"10.1016\/j.mam.2026.101500_bib73","first-page":"62","article-title":"Maternal pre-pregnancy body mass index differentially regulates intracellular pH in human umbilical vein endothelium from gestational diabetes mellitus, with alkalinisation-associated reduction of adenosine transport in normal-weight pregnancies","volume":"478","author":"Fuentes","year":"2026","journal-title":"Diabetologia"},{"issue":"7","key":"10.1016\/j.mam.2026.101500_bib74","doi-asserted-by":"crossref","DOI":"10.1007\/s00424-026-03193-w","article-title":"A conceptual review of intracellular pH as a regulator of the adenosine\u2013L-arginine\u2013nitric oxide (ALANO) axis in human fetoplacental endothelial dysfunction in gestational diabetes mellitus","volume":"478","author":"Fuentes","year":"2026","journal-title":"Pfl\u00fcgers Archiv. Eur. J. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib75","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.placenta.2022.11.012","article-title":"The new landscape of differentially expression proteins in placenta tissues of gestational diabetes based on iTRAQ proteomics","volume":"131","author":"Ge","year":"2023","journal-title":"Placenta"},{"key":"10.1016\/j.mam.2026.101500_bib76","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1006\/dbio.2001.0231","article-title":"Human cytotrophoblast expression of the von Hippel-Lindau protein is downregulated during uterine invasion in situ and upregulated by hypoxia in vitro","volume":"15","author":"Genbacev","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.mam.2026.101500_bib77","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jcjd.2023.12.007","article-title":"Risk of breast cancer after diabetes in pregnancy: a population-based cohort study","volume":"48","author":"Gill","year":"2024","journal-title":"Can. J. Diabetes"},{"key":"10.1016\/j.mam.2026.101500_bib78","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s12943-023-01827-6","article-title":"PI3K\/AKT\/mTOR signaling transduction pathway and targeted therapies in cancer","volume":"22","author":"Glaviano","year":"2023","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib79","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41574-018-0096-z","article-title":"The role of hypoxia-inducible factors in metabolic diseases","volume":"15","author":"Gonzalez","year":"2018","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.mam.2026.101500_bib80","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.immuni.2019.06.025","article-title":"Inflammation and cancer: triggers, mechanisms, and consequences","volume":"51","author":"Greten","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.mam.2026.101500_bib81","doi-asserted-by":"crossref","DOI":"10.1080\/14767058.2025.2491454","article-title":"Maternal and cord serum levels of sFlt-1 and PlGF in pregnancies complicated by gestational diabetes mellitus: a prospective cohort study","volume":"38","author":"Gul Kara","year":"2025","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"10.1016\/j.mam.2026.101500_bib82","first-page":"1997","article-title":"ERK\/MAPK signalling pathway and tumorigenesis","volume":"19","author":"Guo","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.mam.2026.101500_bib83","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.molcel.2008.03.003","article-title":"AMPK phosphorylation of raptor mediates a metabolic checkpoint","volume":"30","author":"Gwinn","year":"2008","journal-title":"Mol. Cell"},{"key":"10.1016\/j.mam.2026.101500_bib84","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s13148-017-0329-3","article-title":"Epigenetic signatures of gestational diabetes mellitus on cord blood methylation","volume":"9","author":"Haertle","year":"2017","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.mam.2026.101500_bib85","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/medicina61010001","article-title":"Association of pregnancy complications with endometrial or ovarian or breast cancer: a case control study","volume":"61","author":"Han","year":"2024","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.mam.2026.101500_bib86","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1038\/s41572-019-0111-2","article-title":"Breast cancer","volume":"5","author":"Harbeck","year":"2019","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.mam.2026.101500_bib87","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nrm3311","article-title":"AMPK: a nutrient and energy sensor that maintains energy homeostasis","volume":"13","author":"Hardie","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.mam.2026.101500_bib88","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.smim.2014.05.004","article-title":"Regulation of NF-\u03baB by TNF family cytokines","volume":"26","author":"Hayden","year":"2014","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.mam.2026.101500_bib89","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.placenta.2023.08.070","article-title":"Regulatory mechanisms underlying endoplasmic reticulum stress involvement in the development of gestational diabetes mellitus entail the CHOP-PPAR\u03b1-NF-\u03baB pathway","volume":"142","author":"He","year":"2023","journal-title":"Placenta"},{"key":"10.1016\/j.mam.2026.101500_bib90","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nrm.2017.95","article-title":"AMPK: guardian of metabolism and mitochondrial homeostasis","volume":"19","author":"Herzig","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.mam.2026.101500_bib91","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1080\/15592294.2022.2111755","article-title":"Placental DNA methylation in pregnancies complicated by maternal diabetes and\/or obesity: state of the art and research gaps","volume":"17","author":"Hjort","year":"2022","journal-title":"Epigenetics"},{"key":"10.1016\/j.mam.2026.101500_bib92","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1186\/s12885-016-2259-4","article-title":"TNF-alpha promotes lymphangiogenesis and lymphatic metastasis of gallbladder cancer through the ERK1\/2\/AP-1\/VEGF-D pathway","volume":"16","author":"Hong","year":"2016","journal-title":"BMC Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib93","doi-asserted-by":"crossref","first-page":"98","DOI":"10.2337\/dc19-0524","article-title":"Maternal gestational diabetes mellitus and newborn DNA methylation: findings from the pregnancy and childhood epigenetics consortium","volume":"43","author":"Howe","year":"2020","journal-title":"Diabetes Care"},{"key":"10.1016\/j.mam.2026.101500_bib94","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.4239\/wjd.v12.i11.1894","article-title":"p66Shc-mediated oxidative stress is involved in gestational diabetes mellitus","volume":"12","author":"Huang","year":"2021","journal-title":"World J. Diabetes"},{"key":"10.1016\/j.mam.2026.101500_bib95","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/s41420-024-01895-7","article-title":"Dual inhibitors of DNMT and HDAC induce viral mimicry to induce antitumour immunity in breast cancer","volume":"10","author":"Huang","year":"2024","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.mam.2026.101500_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2025.123404","article-title":"NanoCRISPR-assisted biomimetic tissue-equivalent patch regenerates the intervertebral disc by inhibiting endothelial-to-mesenchymal transition","volume":"322","author":"Huang","year":"2025","journal-title":"Biomaterials"},{"key":"10.1016\/j.mam.2026.101500_bib97","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2018.12.010","article-title":"Human placental glucose transport in fetoplacental growth and metabolism","volume":"1866","author":"Illsley","year":"2020","journal-title":"Biochim. Biophys. Acta \u2013 Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib98","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1387\/ijdb.082798ni","article-title":"Placental metabolic reprogramming: do changes in the mix of energy-generating substrates modulate fetal growth?","volume":"54","author":"Illsley","year":"2010","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.mam.2026.101500_bib99","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0092-8674(03)00929-2","article-title":"TSC2 mediates cellular energy response to control cell growth and survival","volume":"115","author":"Inoki","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.mam.2026.101500_bib100","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/72212","article-title":"Leaky vessels? Call Ang1","volume":"6","author":"Jain","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.mam.2026.101500_bib101","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.canlet.2020.11.017","article-title":"PCDH10 exerts tumor-suppressor functions through modulation of EGFR\/AKT axis in colorectal cancer","volume":"499","author":"Jao","year":"2021","journal-title":"Cancer Lett."},{"key":"10.1016\/j.mam.2026.101500_bib102","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0015-0282(02)04568-5","article-title":"Comparison of ultrasonographic and Doppler mapping of the intervillous circulation in normal and abnormal early pregnancies","volume":"79","author":"Jauniaux","year":"2003","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.mam.2026.101500_bib103","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1210\/jc.2018-01599","article-title":"Adipose tissue exosomal proteomic profile reveals a role on placenta glucose metabolism in gestational diabetes mellitus","volume":"104","author":"Jayabalan","year":"2019","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.mam.2026.101500_bib104","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101534","article-title":"Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway","volume":"32","author":"Jia","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.mam.2026.101500_bib105","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/ncb2172","article-title":"p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase","volume":"13","author":"Jiang","year":"2011","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.mam.2026.101500_bib106","doi-asserted-by":"crossref","first-page":"C537","DOI":"10.1152\/ajpcell.00329.2016","article-title":"Vascular biology of hydrogen sulfide","volume":"312","author":"Kanagy","year":"2017","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib107","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/s00404-019-05408-1","article-title":"Placental protein expression of kisspeptin-1 (KISS1) and the kisspeptin-1 receptor (KISS1R) in pregnancy complicated by diabetes mellitus or preeclampsia","volume":"301","author":"Kapustin","year":"2020","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.mam.2026.101500_bib108","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3389\/fnmol.2011.00051","article-title":"PI3K\/AKT\/mTOR pathway in angiogenesis","volume":"4","author":"Karar","year":"2011","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.mam.2026.101500_bib109","first-page":"2401","article-title":"Global trends in prevalence of maternal overweight and obesity: a systematic review and meta-analysis of routinely collected data retrospective cohorts","volume":"9","author":"Kent","year":"2024","journal-title":"Int. J. Popul. Data Sci."},{"key":"10.1016\/j.mam.2026.101500_bib110","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.placenta.2018.04.006","article-title":"Foetoplacental epigenetic changes associated with maternal metabolic dysfunction","volume":"69","author":"Kerr","year":"2018","journal-title":"Placenta"},{"key":"10.1016\/j.mam.2026.101500_bib111","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.3390\/molecules27113389","article-title":"Hydrogen sulfide biology and its role in cancer","volume":"27","author":"Khattak","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.mam.2026.101500_bib112","doi-asserted-by":"crossref","first-page":"3724","DOI":"10.1038\/s41467-023-39287-7","article-title":"Hypoxia induced responses are reflected in the stromal proteome of breast cancer","volume":"14","author":"Kj\u00f8lle","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mam.2026.101500_bib113","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2021.100787","article-title":"Hypoxia as a driver of resistance to immunotherapy","volume":"59","author":"Kopecka","year":"2021","journal-title":"Drug Resist. Updat."},{"key":"10.1016\/j.mam.2026.101500_bib114","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s12933-024-02184-4","article-title":"Postpartum weight retention and the early evolution of cardiovascular risk over the first 5 years after pregnancy","volume":"23","author":"Kramer","year":"2024","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.mam.2026.101500_bib115","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242216082","article-title":"Impaired angiogenic function of fetal endothelial progenitor cells via PCDH10 in gestational diabetes mellitus","volume":"24","author":"Kwon","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib116","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.3390\/genes16091060","article-title":"MicroRNA (miRNA) in the pathogenesis of diabetic retinopathy: a narrative review","volume":"16","author":"Lampsas","year":"2025","journal-title":"Genes"},{"key":"10.1016\/j.mam.2026.101500_bib117","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.3390\/biomedicines10092272","article-title":"Proteomic approaches in the study of placenta of pregnancy complicated by gestational diabetes mellitus","volume":"10","author":"Lapolla","year":"2022","journal-title":"Biomedicines"},{"key":"10.1016\/j.mam.2026.101500_bib118","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.mce.2013.09.011","article-title":"Activation of inflammasomes in adipose tissue of women with gestational diabetes","volume":"382","author":"Lappas","year":"2014","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.mam.2026.101500_bib119","doi-asserted-by":"crossref","first-page":"262","DOI":"10.2119\/molmed.2010.00005","article-title":"Gene expression profiling of the hedgehog signaling pathway in human meningiomas","volume":"16","author":"Laurendeau","year":"2010","journal-title":"Mol. Med."},{"key":"10.1016\/j.mam.2026.101500_bib120","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/s41392-025-02249-0","article-title":"Vascular endothelial growth factor signaling in health and disease: from molecular mechanisms to therapeutic perspectives","volume":"10","author":"Lee","year":"2025","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.mam.2026.101500_bib121","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.tiv.2009.11.002","article-title":"Protective effects of dieckol isolated from Ecklonia cava against high glucose-induced oxidative stress in human umbilical vein endothelial cells","volume":"24","author":"Lee","year":"2010","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.mam.2026.101500_bib122","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1179101","article-title":"The discrete roles of individual FOXO transcription factor family members in B-cell malignancies","volume":"14","author":"Lees","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.mam.2026.101500_bib123","article-title":"Association between gestational diabetes mellitus and risk of breast cancer: a systematic review and meta-analysis","volume":"16","author":"Li","year":"2025","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.mam.2026.101500_bib124","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3892\/or.2021.8019","article-title":"Therapeutic potential of endogenous hydrogen sulfide inhibition in breast cancer","volume":"45","author":"Li","year":"2021","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.mam.2026.101500_bib125","doi-asserted-by":"crossref","first-page":"9361","DOI":"10.3390\/ijms25179361","article-title":"Deciphering DNA methylation in gestational diabetes mellitus: epigenetic regulation and potential clinical applications","volume":"25","author":"Li","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib126","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1038\/s41392-023-01400-z","article-title":"Diabetic vascular diseases: molecular mechanisms and therapeutic strategies","volume":"8","author":"Li","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.mam.2026.101500_bib127","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.lungcan.2018.07.015","article-title":"The intratumoral distribution influences the prognostic impact of CD68- and CD204-positive macrophages in non-small cell lung cancer","volume":"123","author":"Li","year":"2018","journal-title":"Lung Cancer Amst. Neth."},{"key":"10.1016\/j.mam.2026.101500_bib128","first-page":"86","article-title":"Effect of NLRP3 inflammasome on lung cancer immune microenvironment activation and its mechanism","volume":"30","author":"Li","year":"2024","journal-title":"Alternative Ther. Health Med."},{"key":"10.1016\/j.mam.2026.101500_bib129","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.tibs.2015.12.001","article-title":"The Warburg effect: how does it benefit cancer cells?","volume":"41","author":"Liberti","year":"2016","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib130","doi-asserted-by":"crossref","first-page":"9185","DOI":"10.1038\/s41467-025-64214-3","article-title":"HIF\u03b1 isoform specific activities drive cell-type specificity of VHL-associated oncogenesis","volume":"16","author":"Lima","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mam.2026.101500_bib131","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-024-06919-9","article-title":"Proteomic analysis of plasma total exosomes and placenta-derived exosomes in patients with gestational diabetes mellitus in the first and second trimesters","volume":"24","author":"Lin","year":"2024","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.mam.2026.101500_bib132","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/1500768","article-title":"Upregulation of klotho aggravates insulin resistance in gestational diabetes mellitus trophoblast cells","volume":"2022","author":"Lin","year":"2022","journal-title":"Genet. Res."},{"key":"10.1016\/j.mam.2026.101500_bib133","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2022.103777","article-title":"Circulating angiotensin II type I receptor - autoantibodies in diabetic pregnancies","volume":"155","author":"Linge","year":"2023","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.mam.2026.101500_bib134","article-title":"NF-\u03baB signaling in inflammation","volume":"2","author":"Liu","year":"2017","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.mam.2026.101500_bib135","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s13287-022-02927-8","article-title":"Human umbilical cord-derived mesenchymal stem cells not only ameliorate blood glucose but also protect vascular endothelium from diabetic damage through a paracrine mechanism mediated by MAPK\/ERK signaling","volume":"13","author":"Liu","year":"2022","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.mam.2026.101500_bib136","article-title":"Complications of pregnancy and the risk of developing endometrial or ovarian cancer: a case-control study","volume":"12","author":"Liu","year":"2021","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.mam.2026.101500_bib137","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/labinvest.2016.149","article-title":"GDM alters paracrine regulation of feto-placental angiogenesis via the trophoblast","volume":"97","author":"Loegl","year":"2017","journal-title":"Lab. Investig. J. Tech. Methods Pathol."},{"key":"10.1016\/j.mam.2026.101500_bib138","article-title":"Constitutional epimutations: from rare events toward major cancer risk factors?","volume":"9","author":"L\u00f8nning","year":"2025","journal-title":"JCO Precis. Oncol."},{"key":"10.1016\/j.mam.2026.101500_bib139","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1007\/s00018-019-03351-7","article-title":"Tumor angiogenesis: causes, consequences, challenges and opportunities","volume":"77","author":"Lugano","year":"2020","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.mam.2026.101500_bib140","article-title":"Hypoxia-inducible miR-210 contributes to preeclampsia via targeting thrombospondin type I domain containing 7A","volume":"6","author":"Luo","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mam.2026.101500_bib141","article-title":"Epigenetics of maternal-fetal interface immune microenvironment and placental related pregnancy complications","volume":"16","author":"Ma","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.mam.2026.101500_bib142","doi-asserted-by":"crossref","first-page":"106","DOI":"10.3390\/biology14020106","article-title":"Fetal mammary gland development and offspring's breast cancer risk in adulthood","volume":"14","author":"Mabasa","year":"2025","journal-title":"Biology"},{"key":"10.1016\/j.mam.2026.101500_bib143","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0037203","article-title":"Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosis","volume":"7","author":"Macanas-Pirard","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2026.101500_bib144","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.3390\/ijms25063313","article-title":"A molecular perspective on HIF-1\u03b1 and angiogenic stimulator networks and their role in solid tumors: an update","volume":"25","author":"Magar","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib145","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1152\/physrev.00022.2002","article-title":"Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells","volume":"83","author":"Mann","year":"2003","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.mam.2026.101500_bib146","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/s41423-025-01310-w","article-title":"NF-\u03baB in inflammation and cancer","volume":"22","author":"Mao","year":"2025","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.mam.2026.101500_bib147","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1186\/s13046-019-1384-8","article-title":"Hypoxic exosomes facilitate angiogenesis and metastasis in esophageal squamous cell carcinoma through altering the phenotype and transcriptome of endothelial cells","volume":"38","author":"Mao","year":"2019","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.mam.2026.101500_bib148","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1007\/BF00121214","article-title":"Acidic pH enhances the invasive behavior of human melanoma cells","volume":"14","author":"Mart\u00ednez-Zaguil\u00e1n","year":"1996","journal-title":"Clin. Exp. Metastasis"},{"key":"10.1016\/j.mam.2026.101500_bib149","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/20459","article-title":"The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis","volume":"399","author":"Maxwell","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.mam.2026.101500_bib150","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1007\/s00125-002-0927-1","article-title":"Enhanced fetoplacental angiogenesis in pre-gestational diabetes mellitus: the extra growth is exclusively longitudinal and not accompanied by microvascular remodelling","volume":"45","author":"Mayhew","year":"2002","journal-title":"Diabetologia"},{"key":"10.1016\/j.mam.2026.101500_bib151","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2023.104171","article-title":"L-ergothioneine reduces mitochondrial-driven NLRP3 activation in gestational diabetes mellitus","volume":"161","author":"McElwain","year":"2024","journal-title":"J. Reprod. Immunol."},{"issue":"Suppl. 3","key":"10.1016\/j.mam.2026.101500_bib152","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/dom.16361","article-title":"A narrative review of metformin in pregnancy: navigating benefit and uncertainty","volume":"27","author":"McEvoy","year":"2025","journal-title":"Diabetes Obes. Metabol."},{"key":"10.1016\/j.mam.2026.101500_bib153","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2024.1494072","article-title":"The role of DNA methylation in placental development and its implications for preeclampsia","volume":"12","author":"Meng","year":"2024","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.mam.2026.101500_bib154","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1158\/1078-0432.CCR-16-0534","article-title":"Essential role of DNA methyltransferase 1-mediated transcription of insulin-like growth factor 2 in resistance to histone deacetylase inhibitors","volume":"23","author":"Min","year":"2017","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.mam.2026.101500_bib155","first-page":"65","article-title":"Endocrine and metabolic adaptations to pregnancy; impact of obesity","volume":"24","author":"Mouzon","year":"2015","journal-title":"Horm. Mol. Biol. Clin. Invest."},{"key":"10.1016\/j.mam.2026.101500_bib156","doi-asserted-by":"crossref","first-page":"160","DOI":"10.4103\/ijem.ijem_453_24","article-title":"A critical review on varied aspects of gestational diabetes mellitus (GDM) and it's associations with placenta","volume":"29","author":"Mukhopadhyay","year":"2025","journal-title":"Indian J. Endocrinol. Metab."},{"key":"10.1016\/j.mam.2026.101500_bib157","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1016\/j.placenta.2012.06.006","article-title":"Oxygen delivery and fetal-placental growth: beyond a question of supply and demand?","volume":"33","author":"Murray","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.mam.2026.101500_bib158","doi-asserted-by":"crossref","DOI":"10.1016\/j.tice.2024.102678","article-title":"Netrin-1: key insights in neural development and disorders","volume":"93","author":"Nabeel Mustafa","year":"2025","journal-title":"Tissue Cell"},{"key":"10.1016\/j.mam.2026.101500_bib159","article-title":"Metabolic reprogramming in cancer: mechanisms and therapeutics","volume":"4","author":"Nong","year":"2023","journal-title":"MedComm (Beijing)"},{"key":"10.1016\/j.mam.2026.101500_bib160","doi-asserted-by":"crossref","DOI":"10.1080\/14767058.2025.2521799","article-title":"Reduced M3 muscarinic acetylcholine receptor expression in gestational diabetes mellitus: implications for placental dysfunction and vascular regulation","volume":"38","author":"O\u011flak","year":"2025","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"10.1016\/j.mam.2026.101500_bib161","doi-asserted-by":"crossref","first-page":"10017","DOI":"10.1080\/14767058.2022.2083495","article-title":"The reduced serum concentrations of \u03b2-arrestin-1 and \u03b2-arrestin-2 in pregnancies complicated with gestational diabetes mellitus","volume":"35","author":"O\u011flak","year":"2022","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"10.1016\/j.mam.2026.101500_bib162","doi-asserted-by":"crossref","first-page":"8087","DOI":"10.3390\/ijms22158087","article-title":"Immunoendocrine dysregulation during gestational diabetes mellitus: the central role of the placenta","volume":"22","author":"Olmos-Ortiz","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib163","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0326087","article-title":"Placental inflammation is increased in gestational diabetes mellitus: the role of inflammasome NLRP-3 and chemokine scavenger decoy receptor D6","volume":"20","author":"Onori","year":"2025","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2026.101500_bib164","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.3390\/antiox12071396","article-title":"Inhibitors of NLRP3 inflammasome in ischemic heart disease: focus on functional and redox aspects","volume":"12","author":"Pagliaro","year":"2023","journal-title":"Antioxid. Basel Switz."},{"key":"10.1016\/j.mam.2026.101500_bib165","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1388253","article-title":"Knowledge mapping of metformin use on cancers: a bibliometric analysis (2013-2023)","volume":"15","author":"Pan","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.mam.2026.101500_bib166","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/cvr\/cvq055","article-title":"High glucose, nitric oxide, and adenosine: a vicious circle in chronic hyperglycaemia?","volume":"86","author":"Pandolfi","year":"2010","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.mam.2026.101500_bib167","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.cmet.2006.01.012","article-title":"HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption","volume":"3","author":"Papandreou","year":"2006","journal-title":"Cell Metab."},{"key":"10.1016\/j.mam.2026.101500_bib168","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.mam.2017.11.010","article-title":"Extracellular vesicles in obesity and diabetes mellitus","volume":"60","author":"Pardo","year":"2018","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.mam.2026.101500_bib169","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.mam.2016.12.002","article-title":"Pharmacological targeting of adenosine receptor signaling","volume":"55","author":"Peleli","year":"2017","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.mam.2026.101500_bib170","article-title":"PI3K\/Akt\/mTOR pathway and its role in cancer therapeutics: are we making headway?","volume":"12","author":"Peng","year":"2022","journal-title":"Front. Oncol."},{"key":"10.1016\/j.mam.2026.101500_bib171","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2018-024583","article-title":"Incidence and relative risk for developing cancers in women with gestational diabetes mellitus: a nationwide cohort study in Taiwan","volume":"9","author":"Peng","year":"2019","journal-title":"BMJ Open"},{"key":"10.1016\/j.mam.2026.101500_bib172","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1002\/iub.2905","article-title":"Extracellular adenosine oppositely regulates the purinome machinery in glioblastoma and mesenchymal stem cells","volume":"76","author":"Pietrobono","year":"2024","journal-title":"IUBMB Life"},{"key":"10.1016\/j.mam.2026.101500_bib173","doi-asserted-by":"crossref","DOI":"10.1002\/1878-0261.70223","article-title":"EDNRB-dependent endothelin signaling reduces proliferation and promotes proneural-to-mesenchymal transition in gliomas","author":"Pineau","year":"2026","journal-title":"Mol. Oncol."},{"key":"10.1016\/j.mam.2026.101500_bib174","doi-asserted-by":"crossref","first-page":"3342","DOI":"10.3390\/ijms19113342","article-title":"The pathophysiology of gestational diabetes mellitus","volume":"19","author":"Plows","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib175","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.3390\/ijms20061408","article-title":"Downregulation of the netrin-1 receptor UNC5B underlies increased placental angiogenesis in human gestational diabetes mellitus","volume":"20","author":"Prieto","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib176","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.cell.2010.03.014","article-title":"Macrophage diversity enhances tumor progression and metastasis","volume":"141","author":"Qian","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.mam.2026.101500_bib177","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1756-9966-33-50","article-title":"Multiple functions of hypoxia-regulated miR-210 in cancer","volume":"33","author":"Qin","year":"2014","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.mam.2026.101500_bib178","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.2337\/diabetes.52.12.2951","article-title":"Gestational diabetes induces placental genes for chronic stress and inflammatory pathways","volume":"52","author":"Radaelli","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.mam.2026.101500_bib179","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/j.cell.2010.03.030","article-title":"c-Myc regulates transcriptional pause release","volume":"141","author":"Rahl","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.mam.2026.101500_bib180","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.bbadis.2018.01.032","article-title":"Intracellular acidification reduces l-arginine transport via system y+L but not via system y+\/CATs and nitric oxide synthase activity in human umbilical vein endothelial cells","volume":"1864","author":"Ram\u00edrez","year":"2018","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib181","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1126\/science.aaf4405","article-title":"Hypoxic control of metastasis","volume":"352","author":"Rankin","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.mam.2026.101500_bib182","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1186\/s13098-025-01897-0","article-title":"Exploring the role of miR-126 in diabetes and its complications: a comprehensive review","volume":"17","author":"Rasmi","year":"2025","journal-title":"Diabetol. Metab. Syndr."},{"key":"10.1016\/j.mam.2026.101500_bib183","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1146\/annurev-cancerbio-041916-065808","article-title":"The two faces of reactive oxygen species in cancer","volume":"1","author":"Reczek","year":"2017","journal-title":"Ann. Rev. Cancer Biol."},{"key":"10.1016\/j.mam.2026.101500_bib184","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.trecan.2023.08.005","article-title":"Stress granules and hormetic adaptation of cancer","volume":"9","author":"Redding","year":"2023","journal-title":"Trends Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib185","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1503\/cmaj.090569","article-title":"Mild glucose intolerance in pregnancy and risk of cardiovascular disease: a population-based cohort study","volume":"181","author":"Retnakaran","year":"2009","journal-title":"CMAJ"},{"key":"10.1016\/j.mam.2026.101500_bib186","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1038\/nrc3628","article-title":"Crossing the endothelial barrier during metastasis","volume":"13","author":"Reymond","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib187","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.critrevonc.2018.05.016","article-title":"A revisited concept. Tumors: wounds that do not heal","volume":"128","author":"Ribatti","year":"2018","journal-title":"Crit. Rev. Oncol. Hematol."},{"key":"10.1016\/j.mam.2026.101500_bib188","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/nrc3546","article-title":"Endothelin 1 in cancer: biological implications and therapeutic opportunities","volume":"13","author":"Rosan\u00f2","year":"2013","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib189","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1113\/JP290546","article-title":"Reframing gestational diabetes mellitus through two new paradigms: early detection and lifelong intergenerational follow-up","volume":"604","author":"Rudge","year":"2026","journal-title":"J Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib190","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1096\/fj.201800640RR","article-title":"Pro- and antiangiogenic therapies: current status and clinical implications","volume":"33","author":"Rust","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.mam.2026.101500_bib191","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.bbadis.2017.11.010","article-title":"Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus","volume":"1864","author":"S\u00e1ez","year":"2018","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib192","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.semcancer.2022.12.005","article-title":"Cancer plasticity: investigating the causes for this agility","volume":"88","author":"Saha","year":"2023","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.mam.2026.101500_bib193","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0040578","article-title":"Gestational diabetes reduces adenosine transport in human placental microvascular endothelium, an effect reversed by insulin","volume":"7","author":"Salom\u00f3n","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2026.101500_bib194","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.placenta.2005.01.011","article-title":"Gestational diabetes and the adenosine\/l-Arginine\/nitric oxide (ALANO) pathway in human umbilical vein endothelium","volume":"27","author":"San Mart\u00edn","year":"2006","journal-title":"Placenta"},{"key":"10.1016\/j.mam.2026.101500_bib195","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.bbadis.2016.10.013","article-title":"Sodium\/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer","volume":"1863","author":"Sanhueza","year":"2017","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib196","doi-asserted-by":"crossref","first-page":"23","DOI":"10.2174\/1566524016666151222143437","article-title":"Modulation of intracellular pH in human ovarian cancer","volume":"16","author":"Sanhueza","year":"2016","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.mam.2026.101500_bib197","article-title":"AngiomiRs: potential biomarkers of pregnancy's vascular pathologies","volume":"2015","author":"Santa","year":"2015","journal-title":"J Pregnancy"},{"key":"10.1016\/j.mam.2026.101500_bib198","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1007\/s00592-023-02137-5","article-title":"Position paper of the Italian Association of Medical Diabetologists (AMD), Italian Society of Diabetology (SID), and the Italian Study Group of Diabetes in pregnancy: metformin use in pregnancy","volume":"60","author":"Sciacca","year":"2023","journal-title":"Acta Diabetol."},{"key":"10.1016\/j.mam.2026.101500_bib199","doi-asserted-by":"crossref","first-page":"8240","DOI":"10.1038\/sj.onc.1206058","article-title":"In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A","volume":"21","author":"Sciacca","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.mam.2026.101500_bib200","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/nrc1187","article-title":"Targeting HIF-1 for cancer therapy","volume":"3","author":"Semenza","year":"2003","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib201","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1146\/annurev-pathol-012513-104720","article-title":"Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology","volume":"9","author":"Semenza","year":"2014","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.mam.2026.101500_bib202","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.3390\/cells11172672","article-title":"Deep insight of the pathophysiology of gestational diabetes mellitus","volume":"11","author":"Sharma","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.mam.2026.101500_bib203","doi-asserted-by":"crossref","DOI":"10.1007\/164_2026_803","article-title":"Are there common mechanisms and consequences of placental endothelial dysfunction in women with gestational diabetes mellitus and pre-eclampsia?","volume":"19","author":"Silva","year":"2026","journal-title":"Handb. Exp. Pharmacol. May"},{"key":"10.1016\/j.mam.2026.101500_bib204","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.mam.2016.11.002","article-title":"Insulin\/adenosine axis linked signaling","volume":"55","author":"Silva","year":"2017","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.mam.2026.101500_bib205","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.3390\/biomedicines9091174","article-title":"Is gestational diabetes mellitus a risk factor of maternal breast cancer? A systematic review of the literature","volume":"9","author":"Simon","year":"2021","journal-title":"Biomedicines"},{"key":"10.1016\/j.mam.2026.101500_bib206","doi-asserted-by":"crossref","first-page":"4085","DOI":"10.1113\/JP290342","article-title":"Endothelial physiology in metabolic diseases: from cells to patients","volume":"604","author":"Sobrevia","year":"2026","journal-title":"J Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib207","series-title":"Obstetrics","first-page":"136","article-title":"Placenta function","author":"Sobrevia","year":"2011"},{"key":"10.1016\/j.mam.2026.101500_bib208","doi-asserted-by":"crossref","first-page":"467","DOI":"10.2174\/157016109789043919","article-title":"A role for insulin on L-arginine transport in fetal endothelial dysfunction in hyperglycaemia","volume":"7","author":"Sobrevia","year":"2009","journal-title":"Curr. Vasc. Pharmacol."},{"key":"10.1016\/j.mam.2026.101500_bib209","doi-asserted-by":"crossref","first-page":"C39","DOI":"10.1152\/ajpcell.1994.267.1.C39","article-title":"Adenosine transport in cultured human umbilical vein endothelial cells is reduced in diabetes","volume":"267","author":"Sobrevia","year":"1994","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib210","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2020.165948","article-title":"Mitochondrial dysfunction in the fetoplacental unit in gestational diabetes mellitus","volume":"1866","author":"Sobrevia","year":"2020","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.mam.2026.101500_bib211","series-title":"Fetal Metabolic Programming in Obesity and Diabetes: from Mechanisms to Preventive Therapy (ISBN: 9780443216534), Hot Topics Series in Physiology","article-title":"Obesity in pregnancy and risk and consequences of metabolic diseases","author":"Sobrevia","year":"2026"},{"issue":"11","key":"10.1016\/j.mam.2026.101500_bib212","doi-asserted-by":"crossref","first-page":"2881","DOI":"10.3390\/diagnostics12112881","article-title":"A study of the metabolic pathways affected by gestational diabetes mellitus: comparison with type 2 diabetes","volume":"12","author":"Spanou","year":"2022","journal-title":"Diagnostics"},{"key":"10.1016\/j.mam.2026.101500_bib213","doi-asserted-by":"crossref","first-page":"5346","DOI":"10.1038\/onc.2010.292","article-title":"Extracellular adenosine triphosphate and adenosine in cancer","volume":"29","author":"Stagg","year":"2010","journal-title":"Oncogene"},{"key":"10.1016\/j.mam.2026.101500_bib214","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.coemr.2020.07.005","article-title":"Fetal programming and epigenetics","volume":"13","author":"Stevenson","year":"2020","journal-title":"Curr. Opin. Endocr. Metab. Res."},{"key":"10.1016\/j.mam.2026.101500_bib215","article-title":"Alteration in expression and methylation of IGF2\/H19 in placenta and umbilical cord blood are associated with macrosomia exposed to intrauterine hyperglycemia","volume":"11","author":"Su","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2026.101500_bib216","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1507\/endocrj.EJ21-0189","article-title":"Alterations of transcriptome expression, cell cycle, and mitochondrial superoxide reveal foetal endothelial dysfunction in Saudi women with gestational diabetes mellitus","volume":"68","author":"Sultan","year":"2021","journal-title":"Endocr. J."},{"key":"10.1016\/j.mam.2026.101500_bib217","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1002\/jcp.24993","article-title":"The role of maternal gestational diabetes in inducing fetal endothelial dysfunction","volume":"230","author":"Sultan","year":"2015","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib218","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2024.103302","article-title":"FDX1 downregulation activates mitophagy and the PI3K\/AKT signaling pathway to promote hepatocellular carcinoma progression by inducing ROS production","volume":"75","author":"Sun","year":"2024","journal-title":"Redox Biol."},{"key":"10.1016\/j.mam.2026.101500_bib219","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/s41577-019-0165-0","article-title":"The NLRP3 inflammasome: molecular activation and regulation to therapeutics","volume":"19","author":"Swanson","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.mam.2026.101500_bib220","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1089\/ars.2011.4451","article-title":"Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications","volume":"17","author":"Szabo","year":"2012","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.mam.2026.101500_bib221","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1124\/pr.117.014050","article-title":"International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors","volume":"69","author":"Szabo","year":"2017","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.mam.2026.101500_bib222","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/3085840","article-title":"Expression of H2S in gestational diabetes mellitus and correlation analysis with inflammatory markers IL-6 and TNF-\u03b1","volume":"2020","author":"Teng","year":"2020","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.mam.2026.101500_bib223","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.cell.2009.11.007","article-title":"Epithelial-mesenchymal transitions in development and disease","volume":"139","author":"Thiery","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.mam.2026.101500_bib224","first-page":"1536","article-title":"Loss of imprinting of IGF2 correlates with hypomethylation of the H19 differentially methylated region in the tumor tissue of colorectal cancer patients","volume":"5","author":"Tian","year":"2012","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.mam.2026.101500_bib225","doi-asserted-by":"crossref","first-page":"3677","DOI":"10.1016\/j.molcel.2021.08.015","article-title":"AMPK: restoring metabolic homeostasis over space and time","volume":"81","author":"Trefts","year":"2021","journal-title":"Mol. Cell."},{"key":"10.1016\/j.mam.2026.101500_bib226","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.3390\/cancers16101840","article-title":"Gestational diabetes mellitus and its correlation in the development of pancreatic cancer: a 10-year systematic review","volume":"16","author":"Tsokkou","year":"2024","journal-title":"Cancers"},{"key":"10.1016\/j.mam.2026.101500_bib227","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00204-022-03421-z","article-title":"Molecular mechanisms behind ROS regulation in cancer: a balancing act between augmented tumorigenesis and cell apoptosis","volume":"97","author":"Tuli","year":"2023","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.mam.2026.101500_bib228","doi-asserted-by":"crossref","first-page":"9462","DOI":"10.3390\/ijms22179462","article-title":"Epigenetic alterations related to gestational diabetes mellitus","volume":"22","author":"Valencia-Ortega","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib229","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202000326RR","article-title":"Hyperglycemia and gestational diabetes suppress placental glycolysis and mitochondrial function and alter lipid processing","volume":"35","author":"Valent","year":"2021","journal-title":"FASEB J."},{"key":"10.1016\/j.mam.2026.101500_bib230","doi-asserted-by":"crossref","DOI":"10.1111\/apha.13940","article-title":"Platelets and endothelial dysfunction in gestational diabetes mellitus","volume":"237","author":"Valero","year":"2023","journal-title":"Acta Physiol (Oxf)"},{"key":"10.1016\/j.mam.2026.101500_bib231","doi-asserted-by":"crossref","DOI":"10.1007\/164_2026_823","article-title":"Beyond glucose thresholds: nutrition, glycaemic dynamics and vascular dysfunction in gestational diabetes mellitus","author":"Valero","year":"2026","journal-title":"Handb. Exp. Pharmacol."},{"key":"10.1016\/j.mam.2026.101500_bib232","article-title":"Shortcomings, limitations and gaps in physiological roles of extracellular vesicles in obesity","author":"Valero","year":"2024","journal-title":"J. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib233","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2022.800638","article-title":"Urinary angiotensinogen-melatonin ratio in gestational diabetes and preeclampsia","volume":"9","author":"Valias","year":"2022","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.mam.2026.101500_bib234","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1113\/jphysiol.2004.068288","article-title":"Role of adenosine transport in gestational diabetes-induced l-arginine transport and nitric oxide synthesis in human umbilical vein endothelium","volume":"560","author":"V\u00e1squez","year":"2004","journal-title":"J. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib235","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1113\/JP278810","article-title":"Revisiting the Warburg effect: historical dogma versus current understanding","volume":"599","author":"Vaupel","year":"2021","journal-title":"J. Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib236","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3892\/br.2017.930","article-title":"Human placental growth hormone in normal and abnormal fetal growth","volume":"7","author":"Velegrakis","year":"2017","journal-title":"Biomed Rep"},{"key":"10.1016\/j.mam.2026.101500_bib237","doi-asserted-by":"crossref","first-page":"132","DOI":"10.14715\/cmb\/2020.66.3.20","article-title":"Comparison of the expression levels of TNF-\u03b1, IL-6, hsCRP and sICAM-1 inflammatory factors, bone mineral density and nutritional status between diabetic and normal pregnant women","volume":"66","author":"Wang","year":"2020","journal-title":"Cell. Mol. Biol. (Noisy-le-grand)"},{"key":"10.1016\/j.mam.2026.101500_bib238","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1186\/s12967-025-06754-2","article-title":"DSG3 promotes bladder cancer growth and metastasis via AKT\/GSK3\u03b2\/\u03b2-catenin pathway","volume":"23","author":"Wang","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.mam.2026.101500_bib239","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111210","article-title":"The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations","volume":"40","author":"Wang","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.mam.2026.101500_bib240","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.diabet.2020.02.003","article-title":"The association between gestational diabetes mellitus and cancer in women: a systematic review and meta-analysis of observational studies","volume":"46","author":"Wang","year":"2020","journal-title":"Diabetes Metab."},{"key":"10.1016\/j.mam.2026.101500_bib241","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/jso.23419","article-title":"Loss expression of PHLPP1 correlates with lymph node metastasis and exhibits a poor prognosis in patients with gastric cancer","volume":"108","author":"Wang","year":"2013","journal-title":"J. Surg. Oncol."},{"key":"10.1016\/j.mam.2026.101500_bib242","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/nrc4016","article-title":"Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer","volume":"15","author":"Watson","year":"2015","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib243","doi-asserted-by":"crossref","DOI":"10.1002\/0470868716.ch12","article-title":"Modelling tumour acidity and invasion","author":"Webb","year":"2001"},{"key":"10.1016\/j.mam.2026.101500_bib244","article-title":"Placental and plasma early predictive biomarkers for gestational diabetes mellitus","volume":"16","author":"Wei","year":"2022","journal-title":"Proteonomics Clin. Appl."},{"key":"10.1016\/j.mam.2026.101500_bib245","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1096\/fj.14-254219","article-title":"Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced adenosine transport in human umbilical vein endothelium","volume":"29","author":"Westermeier","year":"2015","journal-title":"FASEB J."},{"key":"10.1016\/j.mam.2026.101500_bib246","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.2337\/db11-0155","article-title":"Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium","volume":"60","author":"Westermeier","year":"2011","journal-title":"Diabetes"},{"key":"10.1016\/j.mam.2026.101500_bib247","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.15252\/embj.201696150","article-title":"Endothelial cell metabolism in health and disease: impact of hypoxia","volume":"36","author":"Wong","year":"2017","journal-title":"EMBO J."},{"key":"10.1016\/j.mam.2026.101500_bib248","year":"2025","journal-title":"Cancer"},{"key":"10.1016\/j.mam.2026.101500_bib249","series-title":"World Obesity Atlas 2025","year":"2025"},{"key":"10.1016\/j.mam.2026.101500_bib250","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3390\/medicina61010096","article-title":"Mitochondrial ribosomal proteins and cancer","volume":"61","author":"Wu","year":"2025","journal-title":"Medicina"},{"key":"10.1016\/j.mam.2026.101500_bib251","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3892\/etm.2021.11017","article-title":"NLRP3 inflammasome activation in gestational diabetes mellitus placentas is associated with hydrogen sulfide synthetase deficiency","volume":"23","author":"Wu","year":"2022","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.mam.2026.101500_bib252","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.envint.2018.10.044","article-title":"Multiple elements related to metabolic markers in the context of gestational diabetes mellitus in meconium","volume":"121","author":"Wu","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.mam.2026.101500_bib253","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1158\/2326-6066.CIR-22-0658","article-title":"Netrin-1 promotes the immunosuppressive activity of MDSCs in colorectal cancer","volume":"11","author":"Xia","year":"2023","journal-title":"Cancer Immunol. Res."},{"key":"10.1016\/j.mam.2026.101500_bib254","doi-asserted-by":"crossref","first-page":"4456","DOI":"10.1038\/s41467-018-06893-9","article-title":"Collagen prolyl 4-hydroxylase 1 is essential for HIF-1\u03b1 stabilization and TNBC chemoresistance","volume":"9","author":"Xiong","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.mam.2026.101500_bib255","article-title":"Effects of DNMT1 and HDAC inhibitors on gene-specific methylation reprogramming during porcine somatic cell nuclear transfer","volume":"8","author":"Xu","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.mam.2026.101500_bib256","doi-asserted-by":"crossref","first-page":"398","DOI":"10.3390\/medicina59020398","article-title":"Placental growth factor and pregnancy-associated plasma protein-A as potential early predictors of gestational diabetes mellitus","volume":"59","author":"Yanachkova","year":"2023","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.mam.2026.101500_bib257","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1007\/s11033-024-09834-6","article-title":"LINC01410 accelerates the invasion of trophoblast cells by modulating METTL3\/Fas","volume":"51","author":"Yang","year":"2024","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.mam.2026.101500_bib258","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-46503-2","article-title":"Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells","volume":"9","author":"Yetkin-Arik","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.mam.2026.101500_bib259","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1186\/s12882-019-1506-8","article-title":"Uric acid regulates NLRP3\/IL-1\u03b2 signaling pathway and further induces vascular endothelial cells injury in early CKD through ROS activation and K+ efflux","volume":"20","author":"Yin","year":"2019","journal-title":"BMC Nephrol."},{"key":"10.1016\/j.mam.2026.101500_bib260","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113491","article-title":"Adenosine derivatives from Cordyceps exert antitumor effects against ovarian cancer cells through ENT1-mediated transport, induction of AMPK signaling, and consequent autophagic cell death","volume":"153","author":"Yoon","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.mam.2026.101500_bib261","doi-asserted-by":"crossref","first-page":"4853","DOI":"10.7150\/ijbs.72838","article-title":"A novel ER stress mediator TMTC3 promotes squamous cell carcinoma progression by activating GRP78\/PERK signaling pathway","volume":"18","author":"Yuan","year":"2022","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.mam.2026.101500_bib262","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1089\/ars.2021.0200","article-title":"miR-210 hypoxamiR in angiogenesis and diabetes","volume":"36","author":"Zaccagnini","year":"2022","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.mam.2026.101500_bib263","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.3389\/fimmu.2017.01750","article-title":"How endothelial cells adapt their metabolism to form Vessels in tumors","volume":"8","author":"Zecchin","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.mam.2026.101500_bib264","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.semcancer.2022.12.002","article-title":"Regulation of epithelial-mesenchymal transition by tumor microenvironmental signals and its implication in cancer therapeutics","volume":"88","author":"Zhang","year":"2023","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.mam.2026.101500_bib265","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/8327486","article-title":"Role of HIF-1\u03b1-miR30a-Snai1 axis in neonatal hyperoxic lung injury","author":"Zhang","year":"2019","journal-title":"Oxid. Med. Cell. Long. 8327486"},{"key":"10.1016\/j.mam.2026.101500_bib266","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1186\/s13287-022-03089-3","article-title":"PFKFB3-mediated glycometabolism reprogramming modulates endothelial differentiation and angiogenic capacity of placenta-derived mesenchymal stem cells","volume":"13","author":"Zhang","year":"2022","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.mam.2026.101500_bib267","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s11658-021-00283-8","article-title":"HIF-1\u03b1\/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury","volume":"3","author":"Zhao","year":"2021","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.mam.2026.101500_bib268","first-page":"127","article-title":"Acupuncture at ST36 alleviates the behavioral disorder of autistic rats by inhibiting TXNIP-mediated activation of NLRP3. J. Neuropathol","volume":"81","author":"Zhao","year":"2022","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.mam.2026.101500_bib269","doi-asserted-by":"crossref","first-page":"8153","DOI":"10.1007\/s00432-023-04743-w","article-title":"The role of Pcdh10 in neurological disease and cancer","volume":"149","author":"Zhen","year":"2023","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"10.1016\/j.mam.2026.101500_bib270","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3892\/ol.2024.14270","article-title":"Roles of endothelial cell specific molecule 1 in tumor angiogenesis","volume":"27","author":"Zhou","year":"2024","journal-title":"Oncol. Lett."},{"key":"10.1016\/j.mam.2026.101500_bib271","doi-asserted-by":"crossref","first-page":"C40","DOI":"10.1152\/ajpcell.00732.2023","article-title":"The HIF2\u03b1-dependent upregulation of SETDB1 facilitates hypoxia-induced functional and phenotypical changes of pulmonary microvascular endothelial cells","volume":"328","author":"Zhou","year":"2025","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.mam.2026.101500_bib272","doi-asserted-by":"crossref","first-page":"764","DOI":"10.3389\/fendo.2019.00764","article-title":"Epigenetic programming and fetal metabolic programming","volume":"10","author":"Zhu","year":"2019","journal-title":"Front. Endocrinol."}],"container-title":["Molecular Aspects of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0098299726000567?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0098299726000567?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:05:57Z","timestamp":1789185957000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0098299726000567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":272,"alternative-id":["S0098299726000567"],"URL":"https:\/\/doi.org\/10.1016\/j.mam.2026.101500","relation":{},"ISSN":["0098-2997"],"issn-type":[{"value":"0098-2997","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vascular dysfunction at the crossroads of gestational diabetes mellitus and cancer","name":"articletitle","label":"Article Title"},{"value":"Molecular Aspects of Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.mam.2026.101500","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101500"}}