{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T05:06:09Z","timestamp":1790226369393,"version":"4.1.0"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BPD\/100740\/2014"],"award-info":[{"award-number":["SFRH\/BPD\/100740\/2014"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BPD\/102870\/2014"],"award-info":[{"award-number":["SFRH\/BPD\/102870\/2014"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BPD\/88947\/2012"],"award-info":[{"award-number":["SFRH\/BPD\/88947\/2012"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003381","name":"Minist\u00e9rio da Educa\u00e7\u00e3o e Ci\u00eancia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013239","name":"Centro de Estudos Ambientais e Marinhos, Universidade de Aveiro","doi-asserted-by":"publisher","award":["UID\/AMB\/50017"],"award-info":[{"award-number":["UID\/AMB\/50017"]}],"id":[{"id":"10.13039\/100013239","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Marine Pollution Bulletin"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.marpolbul.2017.12.028","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T06:56:27Z","timestamp":1515135387000},"page":"733-742","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Addressing the impact of mercury estuarine contamination in the European eel (Anguilla anguilla L., 1758) \u2013 An early diagnosis in glass eel stage based on erythrocytic nuclear morphology"],"prefix":"10.1016","volume":"127","author":[{"given":"D.","family":"Castro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5539-2406","authenticated-orcid":false,"given":"C.L.","family":"Mieiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.P.","family":"Coelho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Guilherme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Marques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.A.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.C.","family":"Duarte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pacheco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.marpolbul.2017.12.028_bb0005","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.marpolbul.2011.11.026","article-title":"Oxidative stress, genotoxicity and histopathology biomarker responses in mullet (Mugil cephalus) and sea bass (Dicentrarchus labrax) liver from Bizerte Lagoon (Tunisia)","volume":"64","author":"Ameur","year":"2012","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0010","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S1383-5718(00)00033-4","article-title":"Induction of micronuclei and other nuclear abnormalities in European minnow Phoxinus phoxinus and mollie Poecilia latipinna: an assessment of the fish micronucleus test","volume":"467","author":"Ayllon","year":"2000","journal-title":"Mutat. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0015","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.mrgentox.2017.05.011","article-title":"Genotoxicity of gemfibrozil in the gilthead seabream (Sparus aurata)","volume":"821","author":"Barreto","year":"2017","journal-title":"Mutat. Res. Genet. Toxicol. Environ. Mutagen."},{"issue":"1","key":"10.1016\/j.marpolbul.2017.12.028_bb0020","first-page":"179","article-title":"Assessing the environmental genotoxicity risk in the Baltic Sea: frequencies of nuclear buds in blood erythrocytes of three native fish species","volume":"187","author":"Bar\u0161ien\u0117","year":"2014","journal-title":"Environ. Monit. Assess."},{"issue":"c","key":"10.1016\/j.marpolbul.2017.12.028_bb0025","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.marenvres.2013.08.012","article-title":"Environmental genotoxicity and cytotoxicity in flounder (Platichthys flesus), herring (Clupea harengus) and Atlantic cod (Gadus morhua) from chemical munitions dumping zones in the southern Baltic Sea","volume":"96","author":"Bar\u0161ien\u0117","year":"2014","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0030","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1006\/jmsc.2000.0723","article-title":"Effects of fishing on the structure and functioning of estuarine and nearshore ecosystems","volume":"57","author":"Blaber","year":"2000","journal-title":"ICES J. Mar. Sci."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0035","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.scitotenv.2013.11.037","article-title":"Dioxin-like, non-dioxin like PCB and PCDD\/F contamination in European eel (Anguilla anguilla) from the Loire estuarine continuum: spatial and biological variabilities","volume":"472","author":"Blanchet-Letrouv\u00e9","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0040","series-title":"Exotic Animal Hematology and Cytology","author":"Campbell","year":"2015"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0045","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00244-012-9812-1","article-title":"Ecotoxicological heterogeneity in transitional coastal habitats assessed through the integration of biomarkers and sediment-contamination profiles: a case study using a commercial clam","volume":"64","author":"Carreira","year":"2013","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0050","series-title":"The Nervous System, Circulation and Respiration","article-title":"Fish physiology. Volume IV","volume":"1970","author":"Caspers","year":"1971"},{"issue":"4","key":"10.1016\/j.marpolbul.2017.12.028_bb0055","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.fct.2004.12.014","article-title":"Induction of micronuclei and binuclei in blood, gill and liver cells of fishes subchronically exposed to cadmium chloride and copper sulphate","volume":"43","author":"\u00c7ava\u015f","year":"2005","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0060","series-title":"Canadian Sediment Quality Guidelines for the Protection of Aquatic Life - Mercury (en)","author":"CCME (Canadian Council of Ministers of the Environment)","year":"1999"},{"issue":"4","key":"10.1016\/j.marpolbul.2017.12.028_bb9000","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/mutage\/get020","article-title":"Relationships among micronuclei, nucleoplasmic bridges and nuclear buds within individual cells in the cytokinesis-block micronucleus assay","volume":"28","author":"Cheong","year":"2013","journal-title":"Mutagenesis"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0065","article-title":"Eels in the Ria de Aveiro, an ex-libris to preserve: biology, health and fishing","author":"CIRA","year":"2015","journal-title":"Aveiro"},{"issue":"16","key":"10.1016\/j.marpolbul.2017.12.028_bb0070","doi-asserted-by":"crossref","first-page":"6481","DOI":"10.1021\/es101185b","article-title":"Impacts of early life exposure to estrogen on subsequent breeding behavior and reproductive success in zebrafish","volume":"44","author":"Coe","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0075","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.ecss.2005.06.020","article-title":"Macroalgae response to a mercury contamination gradient in a temperate coastal lagoon (Ria de Aveiro, Portugal)","volume":"65","author":"Coelho","year":"2005","journal-title":"Estuar. Coast. Shelf Sci."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0080","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.marpolbul.2013.01.021","article-title":"Mercury biomagnification in a contaminated estuary food web: effects of age and trophic position using stable isotope analyses","volume":"69","author":"Coelho","year":"2013","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0085","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.envres.2010.09.011","article-title":"Assessment of the genotoxic potential of contaminated estuarine sediments in fish peripheral blood: laboratory versus in situ studies","volume":"111","author":"Costa","year":"2011","journal-title":"Environ. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0090","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0003-2670(99)00742-4","article-title":"Determination of mercury in environmental and biological samples using pyrolysis atomic absorption spectrometry with gold amalgamation","volume":"405","author":"Costley","year":"2000","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0095","series-title":"Master Thesis","article-title":"Chromosomal damage in fish (Anguilla anguilla L.) induced by the fungicide Macozan\u00ae upon exposure and post-exposure periods","author":"Crespo","year":"2016"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0100","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1161\/CIRCRESAHA.108.173989","article-title":"Nuclear Shape, Mechanics, and Mechano transduction","volume":"102","author":"Dahl","year":"2008","journal-title":"Circ. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0105","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0165-7992(86)90127-2","article-title":"Induction of micronuclei in peripheral erythrocytes of the fish, Heteropneustes fossilis, by mitomycin C and paper mill effluent","volume":"175","author":"Das","year":"1986","journal-title":"Mutat. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb4000","unstructured":"Directive 2010\/63\/EU of the European Parliament and of the Council of 22 September 2010 on the Protection of Animals Used for Scientific Purposes, 2010."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0115","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.ecoenv.2006.06.003","article-title":"Hematological and gill histopathological parameters of three tropical fish species from a polluted lagoon on the west coast of Mauritius","volume":"68","author":"Elahee","year":"2007","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0120","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2174\/1568026013394831","article-title":"Toxic metals and oxidative stress part i: mechanisms involved in metal induced oxidative damage","volume":"1","author":"Ercal","year":"2001","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0125","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0027-5107(00)00065-8","article-title":"The in vitro micronucleus technique","volume":"455","author":"Fenech","year":"2000","journal-title":"Mutat. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0130","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1093\/mutage\/geq052","article-title":"Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells","volume":"26","author":"Fenech","year":"2011","journal-title":"Mutagenesis"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0135","series-title":"Ultrastructural Pathology of the Cell and Matrix","author":"Ghadially","year":"1982"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0140","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.ecoenv.2009.11.009","article-title":"Comparative study about the effects of pollution on glass and yellow eels (Anguilla anguilla) from the estuaries of Minho, Lima and Douro Rivers (NW Portugal)","volume":"73","author":"Gravato","year":"2010","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0145","series-title":"The Evolution of the Genome","first-page":"4","author":"Gregory","year":"2005"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0150","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.marpolbul.2008.02.003","article-title":"Antioxidant and biotransformation responses in Liza aurata under environmental mercury exposure - relationship with mercury accumulation and implications for public health","volume":"56","author":"Guilherme","year":"2008","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0155","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.ecoenv.2007.08.016","article-title":"Erythrocytic nuclear abnormalities in wild and caged fish (Liza aurata) along an environmental mercury contamination gradient","volume":"70","author":"Guilherme","year":"2008","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0160","doi-asserted-by":"crossref","first-page":"8730","DOI":"10.1007\/s11356-014-2803-1","article-title":"DNA and chromosomal damage induced in fish (Anguilla anguilla L.) by aminomethylphosphonic acid (AMPA) \u2014 the major environmental breakdown product of glyphosate","volume":"21","author":"Guilherme","year":"2014","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0165","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/35077232","article-title":"Genome maintenance mechanisms for preventing cancer","volume":"411","author":"Hoeijmakers","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0170","series-title":"ICES Advice","first-page":"1","article-title":"Report of the ICES advisory committee 2012","volume":"Vol. 2013","author":"ICES","year":"2013"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0175","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.aquatox.2011.07.016","article-title":"Growth and condition indices of juvenile turbot, Scophthalmus maximus, exposed to contaminated sediments: effects of metallic and organic compounds","volume":"108","author":"Kerambrun","year":"2012","journal-title":"Aquat. Toxicol."},{"issue":"1\u20132","key":"10.1016\/j.marpolbul.2017.12.028_bb0180","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.mrfmmm.2006.12.002","article-title":"Origin of nuclear buds and micronuclei in normal and folate-deprived human lymphocytes","volume":"617","author":"Lindberg","year":"2007","journal-title":"Mutat. Res. Fundam. Mol. Mech. Mutagen."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0185","series-title":"The Toxicology of Fishes","first-page":"401","article-title":"The osmoregulatory system","author":"Lock","year":"2008"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0190","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.aquatox.2010.07.014","article-title":"Changes in non-specific biomarkers in the Mediterranean barbell (Barbus meridionalis) exposed to sewage effluents in a Mediterranean stream (Catalonia, NE Spain)","volume":"100","author":"Maceda-Veiga","year":"2010","journal-title":"Aquat. Toxicol."},{"issue":"C","key":"10.1016\/j.marpolbul.2017.12.028_bb0195","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.scitotenv.2015.02.004","article-title":"Inside the Redbox: applications of haematology in wildlife monitoring and ecosystem health assessment","volume":"514","author":"Maceda-Veiga","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0200","first-page":"40","article-title":"Assessment of chromosomal damage induced by a deltamethrin-based insecticide in fish (Anguilla anguilla L.) \u2013 a follow-up study upon exposure and post-exposure periods","volume":"113","author":"Marques","year":"2014","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0205","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.seares.2013.07.014","article-title":"Juvenile nursery colonization patterns for the European flounder (Platichthys flesus): a latitudinal approach","volume":"84","author":"Martinho","year":"2013","journal-title":"J. Sea Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0210","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1039\/b821253h","article-title":"Mercury distribution in key tissues of fish (Liza aurata) inhabiting a contaminated estuary-implications for human and ecosystem health risk assessment","volume":"11","author":"Mieiro","year":"2009","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0215","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1007\/s10646-010-0485-0","article-title":"Antioxidant system breakdown in brain of feral golden grey mullet (Liza aurata) as an effect of mercury exposure","volume":"19","author":"Mieiro","year":"2010","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0220","doi-asserted-by":"crossref","first-page":"10638","DOI":"10.1007\/s11356-014-3053-y","article-title":"Mercury accumulation and tissue-specific antioxidant efficiency in the wild European sea bass (Dicentrarchus labrax) with emphasis on seasonality","volume":"21","author":"Mieiro","year":"2014","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.marpolbul.2015.05.054","article-title":"Impairment of mitochondrial energy metabolism of two marine fish by in vitro mercuric chloride exposure","volume":"97","author":"Mieiro","year":"2015","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0230","unstructured":"Mohammed, A. (2013). Why are early life stages of aquatic organisms more sensitive to toxicants than adults? New Insights into Toxicity and Drug Testing. InTech. Chapter 3, edited by Sivakumar Gowder, (ISBN 978-953-51-0946-4, 23, 2013 under CC BY 3.0 license)."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0235","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s00244-012-9799-7","article-title":"Mercury-induced chromosomal damage in wild fish (Dicentrarchus labrax L.) reflecting aquatic contamination in contrasting seasons","volume":"63","author":"Mohmood","year":"2012","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0240","series-title":"Impact of Illegal Glass Eel (Anguilla anguilla) Fishery on Estuarine Fish Stocks: A Case Study in the Mondego Estuary","author":"Neves","year":"2014"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0245","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.chemosphere.2015.04.094","article-title":"Retrospective monitoring of mercury in fish from selected European freshwater and estuary sites","volume":"134","author":"Nguetseng","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0255","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.aquatox.2006.03.010","article-title":"Caging techniques for field exposures of fish to chemical contaminants","volume":"78","author":"Oikari","year":"2006","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0260","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1382-6689(02)00126-6","article-title":"Fish bioaccumulation and biomarkers in environmental risk assessment: a review","volume":"13","author":"van der Oost","year":"2003","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0265","series-title":"Quality Status Report 2000: Region IV\u2014Bay of Biscay and Iberian Coast","article-title":"OSPAR commission 2000","author":"OSPAR","year":"2000"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0270","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ecoenv.2016.06.046","article-title":"Multibiomarker response in ten spotted live-bearer fish Cnesterodon decemmaculatus (Jenyns, 1842) exposed to Reconquista river water","volume":"133","author":"Ossana","year":"2016","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0275","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1006\/eesa.1997.1585","article-title":"Induction of EROD activity and genotoxic effects by polycyclic aromatic hydrocarbons and resin acids on the juvenile eel (Anguilla anguilla L.)","volume":"38","author":"Pacheco","year":"1997","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0280","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0147-6513(02)00017-9","article-title":"Biotransformation, genotoxic, and histopathological effects of environmental contaminants in European eel (Anguilla anguilla L.)","volume":"53","author":"Pacheco","year":"2002","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0285","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s10661-005-5308-z","article-title":"Biotransformation and genotoxic biomarkers in mullet species (Liza SP.) from a contaminated coastal lagoon (Ria De Aveiro, Portugal)","volume":"107","author":"Pacheco","year":"2005","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0290","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.marpolbul.2014.10.022","article-title":"Trace elements distribution and ecological risk assessment of seawater and sediments from Dingzi Bay, Shandong Peninsula, North China","volume":"89","author":"Pan","year":"2014","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0295","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.ecss.2007.08.010","article-title":"Mercury fluxes between an impacted coastal lagoon and the Atlantic Ocean","volume":"76","author":"Pato","year":"2008","journal-title":"Estuar. Coast. Shelf Sci."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0300","doi-asserted-by":"crossref","first-page":"125","DOI":"10.2166\/wst.1998.0744","article-title":"An estimation of industrial mercury stored in sediments of a confined area of the Lagoon of Aveiro (Portugal)","volume":"37","author":"Pereira","year":"1998","journal-title":"Water Sci. Technol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0305","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s10661-008-0416-1","article-title":"Mercury pollution in Ria de Aveiro (Portugal): a review of the system assessment","volume":"155","author":"Pereira","year":"2009","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0310","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.marenvres.2015.10.015","article-title":"Insights into neurosensory toxicity of mercury in fish eyes stemming from tissue burdens, oxidative stress and synaptic transmission profiles","volume":"113","author":"Pereira","year":"2016","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0315","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.ygcen.2011.02.023","article-title":"The role of thyroid hormones in stress response of fish","volume":"172","author":"Peter","year":"2011","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0330","first-page":"81","article-title":"On the mechanism of mercury-induced hemolysis","volume":"2","author":"Ribarov","year":"2010","journal-title":"Gen. Physiol. Biophys."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0335","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.scitotenv.2015.03.017","article-title":"Application of biomarkers in Epaulet grouper (Epinephelus stoliczkae) to assess chromium pollution in the Chabahar Bay and Gulf of Oman","volume":"518-519","author":"Sadeghi","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0340","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1579\/0044-7447(2007)36[12:EOEMOT]2.0.CO;2","article-title":"Effects of environmental methylmercury on the health of wild birds, mammals, and fish","volume":"36","author":"Scheuhammer","year":"2007","journal-title":"Ambio"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0345","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ecss.2013.04.018","article-title":"Evaluation of sediment toxicity in different Portuguese estuaries: ecological impact of metals and polycyclic aromatic hydrocarbons","volume":"130","author":"Serafim","year":"2013","journal-title":"Estuar. Coast. Shelf Sci."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0350","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s10695-014-9984-x","article-title":"Hematological changes and cytogenotoxicity in the tilapia Oreochromis niloticus caused by sub-chronic exposures to mercury and selenium","volume":"41","author":"Seriani","year":"2014","journal-title":"Fish Physiol. Biochem."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0355","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.aquatox.2006.06.013","article-title":"The micronucleus test in piscine erythrocytes","volume":"79","author":"Udroiu","year":"2006","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0360","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.scitotenv.2006.12.048","article-title":"Assessing anthropogenic pressures on estuarine fish nurseries along the Portuguese coast: a multi-metric index and conceptual approach","volume":"374","author":"Vasconcelos","year":"2007","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0365","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1016\/j.chemosphere.2009.06.005","article-title":"Acute effects of copper and mercury on the estuarine fish Pomatoschistus microps: linking biomarkers to behaviour","volume":"76","author":"Vieira","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0370","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.aquatox.2014.11.008","article-title":"Genotoxicity, potential cytotoxicity and cell uptake of titanium dioxide nanoparticles in the marine fish Trachinotus carolinus (Linnaeus, 1766)","volume":"158","author":"Vignardi","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0375","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1242\/jcs.037333","article-title":"Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly","volume":"122","author":"Webster","year":"2009","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.marpolbul.2017.12.028_bb0380","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/nrc1430","article-title":"Nuclear structure in cancer cells","volume":"4","author":"Zink","year":"2004","journal-title":"Nat. Rev. Cancer"}],"container-title":["Marine Pollution Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025326X1731055X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025326X1731055X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T02:06:46Z","timestamp":1656727606000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025326X1731055X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":74,"alternative-id":["S0025326X1731055X"],"URL":"https:\/\/doi.org\/10.1016\/j.marpolbul.2017.12.028","relation":{},"ISSN":["0025-326X"],"issn-type":[{"value":"0025-326X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Addressing the impact of mercury estuarine contamination in the European eel (Anguilla anguilla L., 1758) \u2013 An early diagnosis in glass eel stage based on erythrocytic nuclear morphology","name":"articletitle","label":"Article Title"},{"value":"Marine Pollution Bulletin","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.marpolbul.2017.12.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}