{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T06:30:51Z","timestamp":1783405851635,"version":"3.54.6"},"reference-count":34,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Matrix Biology"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1016\/j.matbio.2008.09.579","type":"journal-article","created":{"date-parts":[[2008,9,23]],"date-time":"2008-09-23T09:07:20Z","timestamp":1222160840000},"page":"661-666","source":"Crossref","is-referenced-by-count":26,"title":["Bone and soft connective tissue alterations result from loss of fibrillin-2 expression"],"prefix":"10.1016","volume":"27","author":[{"given":"Rajeev","family":"Boregowda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy M.","family":"Ritty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.matbio.2008.09.579_bib1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1083\/jcb.200105046","article-title":"Regulation of limb patterning by extracellular microfibrils","volume":"154","author":"Arteaga-Solis","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.matbio.2008.09.579_bib2","doi-asserted-by":"crossref","first-page":"e216","DOI":"10.1371\/journal.pgen.0020216","article-title":"Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis","volume":"2","author":"Bandyopadhyay","year":"2006","journal-title":"PLoS Genet."},{"key":"10.1016\/j.matbio.2008.09.579_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0047-6374(98)00119-5","article-title":"Mechanisms of maturation and ageing of collagen","volume":"106","author":"Bailey","year":"1998","journal-title":"Mechanisms of Ageing and Development"},{"key":"10.1016\/j.matbio.2008.09.579_bib3","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.1074\/jbc.M209201200","article-title":"Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences","volume":"278","author":"Charbonneau","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2008.09.579_bib4","series-title":"Fine Tuning of Growth Factor Signals Depends on Fibrillin Microfibril Networks","author":"Charbonneau","year":"2004"},{"key":"10.1016\/j.matbio.2008.09.579_bib5","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1083\/jcb.200608167","article-title":"Fibrillin-1 regulates the bioavailability of TGFbeta1","volume":"176","author":"Chaudhry","year":"2007","journal-title":"J. Cell. Biol."},{"key":"10.1016\/j.matbio.2008.09.579_bib6","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1126\/science.289.5478.438","article-title":"Interdigital regulation of digit identity and homeotic transformation by modulated BMP signaling","volume":"289","author":"Dahn","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.matbio.2008.09.579_bib7","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/352337a0","article-title":"Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene","volume":"352","author":"Dietz","year":"1991","journal-title":"Nature (Lond.)"},{"key":"10.1016\/j.matbio.2008.09.579_bib8","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/0003-2697(84)90101-5","article-title":"Quantitation of hydroxypyridinium crosslinks in collagen by high-performance liquid chromatography","volume":"137","author":"Eyre","year":"1984","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.matbio.2008.09.579_bib9","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1146\/annurev.bi.53.070184.003441","article-title":"Cross-linking in collagen and elastin","volume":"53","author":"Eyre","year":"1984","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.matbio.2008.09.579_bib10","doi-asserted-by":"crossref","first-page":"2965","DOI":"10.1016\/S0024-3205(03)00169-3","article-title":"The roles of bone morphogenetic protein (BMP) 12 in stimulating the proliferation and matrix production of human patellar tendon fibroblasts","volume":"72","author":"Fu","year":"2003","journal-title":"Life Sci."},{"key":"10.1016\/j.matbio.2008.09.579_bib11","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1242\/dev.122.8.2349","article-title":"Role of TGF beta s and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod","volume":"122","author":"Ganan","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.matbio.2008.09.579_bib12","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.matbio.2006.12.006","article-title":"LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein","volume":"26","author":"Hirani","year":"2007","journal-title":"Matrix Biol."},{"key":"10.1016\/j.matbio.2008.09.579_bib13","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/352330a0","article-title":"Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes","volume":"352","author":"Lee","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.matbio.2008.09.579_bib14","doi-asserted-by":"crossref","first-page":"19059","DOI":"10.1074\/jbc.272.30.19059","article-title":"Transforming growth factor-beta regulation of bone morphogenetic protein-1\/procollagen C-proteinase and related proteins in fibrogenic cells and keratinocytes","volume":"272","author":"Lee","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2008.09.579_bib15","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/S0736-0266(01)00042-0","article-title":"BMP-12 gene transfer augmentation of lacerated tendon repair","volume":"19","author":"Lou","year":"2001","journal-title":"J. Orthop. Res."},{"key":"10.1016\/j.matbio.2008.09.579_bib16","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0076-6879(82)82059-4","article-title":"Preparation and characterization of the different types of collagen","author":"Miller","year":"1982"},{"key":"10.1016\/j.matbio.2008.09.579_bib17","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/ng1116","article-title":"Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome","volume":"33","author":"Neptune","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.matbio.2008.09.579_bib18","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0021-9258(18)56248-7","article-title":"The determination of collagen and elastin in tissues","volume":"186","author":"Neuman","year":"1950","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2008.09.579_bib19","doi-asserted-by":"crossref","first-page":"7113","DOI":"10.1074\/jbc.271.12.7113","article-title":"Metalloproteinase activity secreted by fibrogenic cells in the processing of prolysyl oxidase. Potential role of procollagen C-proteinase","volume":"271","author":"Panchenko","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2008.09.579_bib20","doi-asserted-by":"crossref","first-page":"3819","DOI":"10.1073\/pnas.96.7.3819","article-title":"Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1","volume":"96","author":"Pereira","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.matbio.2008.09.579_bib21","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1073\/pnas.61.2.708","article-title":"The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from bone","volume":"61","author":"Pinnell","year":"1968","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.matbio.2008.09.579_bib22","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0945-053X(02)00100-2","article-title":"Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development","volume":"21","author":"Quondamatteo","year":"2002","journal-title":"Matrix Biol."},{"key":"10.1016\/j.matbio.2008.09.579_bib23","doi-asserted-by":"crossref","first-page":"19489","DOI":"10.1074\/jbc.271.32.19489","article-title":"Fibrillin-1 and fibulin-2 interact and are colocalized in some tissues","volume":"271","author":"Reinhardt","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2008.09.579_bib34","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/rheumatology\/keg448","article-title":"The pathogenesis of tendinopathy. A molecular perspective","volume":"43","author":"Riley","year":"2004","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.matbio.2008.09.579_bib24","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/ar.10175","article-title":"Distribution of the elastic fiber and associated proteins in flexor tendon reflects function","volume":"268","author":"Ritty","year":"2002","journal-title":"Anat. Rec."},{"key":"10.1016\/j.matbio.2008.09.579_bib25","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/S0969-2126(03)00181-3","article-title":"Tendon cell array isolation reveals a previously unknown fibrillin-2 containing macromolecular assembly","volume":"11","author":"Ritty","year":"2003","journal-title":"Structure"},{"key":"10.1016\/j.matbio.2008.09.579_bib26","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1083\/jcb.103.6.2499","article-title":"Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils","volume":"103","author":"Sakai","year":"1986","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.matbio.2008.09.579_bib27","doi-asserted-by":"crossref","first-page":"22537","DOI":"10.1074\/jbc.M102352200","article-title":"Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures","volume":"276","author":"Uzel","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2008.09.579_bib28","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1042\/bj1810639","article-title":"Native cross-links in collagen fibrils induce resistance to human synovial collagenase","volume":"181","author":"Vater","year":"1979","journal-title":"Biochem. J."},{"key":"10.1016\/j.matbio.2008.09.579_bib29","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1172\/JCI119537","article-title":"Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family","volume":"100","author":"Wolfman","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.matbio.2008.09.579_bib30","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1080\/17453670510041330","article-title":"Bone morphogenetic protein 13 stimulates cell proliferation and production of collagen in human patellar tendon fibroblasts","volume":"76","author":"Wong","year":"2005","journal-title":"Acta Orthop."},{"key":"10.1016\/j.matbio.2008.09.579_bib31","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1083\/jcb.129.4.1165","article-title":"Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils","volume":"129","author":"Zhang","year":"1995","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.matbio.2008.09.579_bib32","first-page":"5","article-title":"Development of tendon structure and function: regulation of collagen fibrillogenesis","volume":"5","author":"Zhang","year":"2005","journal-title":"J. Musculoskelet. Neuronal Interact."}],"container-title":["Matrix Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0945053X08007105?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0945053X08007105?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T01:00:37Z","timestamp":1631840437000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0945053X08007105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["S0945053X08007105"],"URL":"https:\/\/doi.org\/10.1016\/j.matbio.2008.09.579","relation":{},"ISSN":["0945-053X"],"issn-type":[{"value":"0945-053X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,10]]}}}