{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:49:58Z","timestamp":1791920998893,"version":"4.3.4"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DK055000"],"award-info":[{"award-number":["R01 DK055000"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DC015385"],"award-info":[{"award-number":["R01 DC015385"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Matrix Biology"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.matbio.2016.08.005","type":"journal-article","created":{"date-parts":[[2016,9,2]],"date-time":"2016-09-02T16:22:54Z","timestamp":1472833374000},"page":"45-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":114,"special_numbering":"C","title":["Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome"],"prefix":"10.1016","volume":"57-58","author":[{"given":"Dominic","family":"Cosgrove","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0732-5230","authenticated-orcid":false,"given":"Shiguang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.matbio.2016.08.005_bb0005","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0945-053X(95)90001-2","article-title":"Basement membrane (type IV) collagen","volume":"14","author":"K\u00fchn","year":"1995","journal-title":"Matrix Biol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0010","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/bies.950180208","article-title":"Supramolecular assembly of basement membranes","volume":"18","author":"Timpl","year":"1996","journal-title":"Bioessays"},{"key":"10.1016\/j.matbio.2016.08.005_bb0015","doi-asserted-by":"crossref","first-page":"30716","DOI":"10.1074\/jbc.M004569200","article-title":"Type IV collagen of the glomerular basement membrane. Evidence that the chain specificity of network assembly is encoded by the noncollagenous NC1 domains","volume":"275","author":"Boutaud","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2016.08.005_bb0020","doi-asserted-by":"crossref","first-page":"2514","DOI":"10.1097\/01.ASN.0000141462.00630.76","article-title":"The molecular basis of Goodpasture and Alport syndromes: beacons for the discovery of the collagen IV family","volume":"15","author":"Hudson","year":"2004","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0025","doi-asserted-by":"crossref","first-page":"35070","DOI":"10.1074\/jbc.M806396200","article-title":"Identification of noncollageneous sites encoding specific interactions and quaternary assembly of \u03b13\u03b14\u03b15(IV) collagen","volume":"283","author":"Kang","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2016.08.005_bb0030","doi-asserted-by":"crossref","first-page":"28532","DOI":"10.1074\/jbc.M103690200","article-title":"The NC1 domain of collagen IV encodes a novel network composed of the alpha 1, alpha 2, alpha 5, and alpha 6 chains in smooth muscle basement membranes","volume":"276","author":"Borza","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2016.08.005_bb0035","doi-asserted-by":"crossref","first-page":"8767","DOI":"10.1074\/jbc.273.15.8767","article-title":"Glomerular basement membrane. Identification of a novel disulfide-cross-linked network of alpha3, alpha4, and alpha5 chains of type IV collagen and its implications for the pathogenesis of Alport syndrome","volume":"273","author":"Gunwar","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2016.08.005_bb0040","first-page":"1221","article-title":"Spectrum of mutations in the COL4A5 collagen gene in X-linked Alport syndrome","volume":"59","author":"Knebelmann","year":"1996","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.matbio.2016.08.005_bb0045","doi-asserted-by":"crossref","first-page":"E1652","DOI":"10.1002\/humu.21312","article-title":"The Alprot syndrome COL4A5 variant database","volume":"31","author":"Crockett","year":"2010","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.matbio.2016.08.005_bb0050","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1681\/ASN.2012121217","article-title":"Evidence for the activation of unfolded protein response in collagen IV nephropathies","volume":"26","author":"Pieri","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0055","doi-asserted-by":"crossref","first-page":"4137","DOI":"10.1016\/S0021-9258(19)50639-1","article-title":"Evidence for separate networks of classical and novel basement membrane collagen. Characterization of alpha 3(IV)-Alport antigen heterodimer","volume":"267","author":"Kleppel","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2016.08.005_bb0060","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1681\/ASN.2008101086","article-title":"Cellular origins of type IV collagen networks in developing glomeruli","volume":"20","author":"Abrahamson","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0065","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nrneph.2013.109","article-title":"The glomerular basement membrane as a barrier to albumin","volume":"9","author":"Suh","year":"2013","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0070","article-title":"Nanoscale protein architecture of the kidney glomerular basement membrane","volume":"2","author":"Suleiman","year":"2013","journal-title":"Elife"},{"key":"10.1016\/j.matbio.2016.08.005_bb0075","doi-asserted-by":"crossref","first-page":"4778","DOI":"10.1016\/S0021-9258(19)34038-4","article-title":"The alpha 2 beta 1 integrin cell surface collagen receptor binds to the alpha 1 (I)-CB3 peptide of collagen","volume":"265","author":"Staatz","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2016.08.005_bb0080","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1006\/exer.2000.0932","article-title":"Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea","volume":"72","author":"Mohan","year":"2001","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.matbio.2016.08.005_bb0085","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1523-1755.2004.00712.x","article-title":"DDR1-deficient mice show localized subepithelial GBM thickening with focal loss of slit diaphragms and proteinuria","volume":"66","author":"Gross","year":"2003","journal-title":"Kidney Int."},{"key":"10.1016\/j.matbio.2016.08.005_bb0090","article-title":"Integrin a2-deficient mice provide insights into the specific functions of collagen receptors in the kideney","volume":"22","author":"Girgert","year":"2010","journal-title":"Fibrogenesis Tissue Repair"},{"key":"10.1016\/j.matbio.2016.08.005_bb0095","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.matbio.2010.03.002","article-title":"Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease","volume":"29","author":"Gross","year":"2010","journal-title":"Matrix Biol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0100","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.matbio.2014.01.006","article-title":"Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice","volume":"34","author":"Rubel","year":"2014","journal-title":"Matrix Biol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0105","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1681\/ASN.2011040367","article-title":"Inhibition of integrin \u03b12\u03b21 ameliorates glomerular injury","volume":"23","author":"Borza","year":"2012","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0110","doi-asserted-by":"crossref","first-page":"081006","DOI":"10.1115\/1.4007098","article-title":"A model of strain-dependent glomerular basement membrane maintenance and its potential ramifications in health and disease","volume":"134","author":"Barocas","year":"2012","journal-title":"J. Biomech. Eng."},{"key":"10.1016\/j.matbio.2016.08.005_bb0115","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1681\/ASN.V5101731","article-title":"Structure-stabilizing forces in the glomerular tuft","volume":"5","author":"Kriz","year":"1995","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0120","doi-asserted-by":"crossref","first-page":"C397","DOI":"10.1152\/ajpcell.00438.2010","article-title":"Biophysical properties of normal and diseased renal glomeruli","volume":"300","author":"Wyss","year":"2011","journal-title":"Am. J. Phys. Cell Physiol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0125","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1038\/ki.2009.324","article-title":"Biomechanical strain causes maladaptive gene regulation, contributing to Alport glomerular disease","volume":"76","author":"Meehan","year":"2009","journal-title":"Kidney Int."},{"key":"10.1016\/j.matbio.2016.08.005_bb0130","first-page":"438","article-title":"Preemptive ramipril therapy delays renal failure and reduces fibrosis in COL4A3-knockout mice with Alport syndrome","volume":"63","author":"Gross","year":"2003"},{"key":"10.1016\/j.matbio.2016.08.005_bb0135","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.kint.2016.02.018","article-title":"Endothelin a receptor activation on mesangial cells initiates Alport glomerular disease","volume":"90","author":"Dufek","year":"2016","journal-title":"Kidney Int."},{"key":"10.1016\/j.matbio.2016.08.005_bb0140","doi-asserted-by":"crossref","first-page":"7616","DOI":"10.1073\/pnas.1337546100","article-title":"Tetraspanin CD151 regulates alpha6beta1 integrin adhesion strengthening","volume":"100","author":"Lammerding","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.matbio.2016.08.005_bb0145","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/nrneph.2012.291","article-title":"Cell-matrix adhesion of podocytes in physiology and disease","volume":"9","author":"Sachs","year":"2013","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0150","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1242\/dev.122.11.3537","article-title":"Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis","volume":"122","author":"Kreidberg","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.matbio.2016.08.005_bb0155","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1083\/jcb.200603073","article-title":"Kidney failure in mice lacking the tetraspanin CD151","volume":"175","author":"Sachs","year":"2006","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0160","doi-asserted-by":"crossref","first-page":"927","DOI":"10.2353\/ajpath.2008.071149","article-title":"Deletion of CD151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane","volume":"173","author":"Baleato","year":"2008","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0165","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1172\/JCI58878","article-title":"Blood pressure influences end-stage renal disease of Cd151 knockout mice","volume":"122","author":"Sachs","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.matbio.2016.08.005_bb0170","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1681\/ASN.2008090984","article-title":"The renal lesions of Alport syndrome","volume":"20","author":"Heidet","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0175","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1038\/ki.2011.407","article-title":"Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy","volume":"81","author":"Gross","year":"2012","journal-title":"Kidney Int."},{"key":"10.1016\/j.matbio.2016.08.005_bb0180","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1681\/ASN.2006040356","article-title":"Renin-angiotensin-aldosterone system and progression of renal disease","volume":"17","author":"R\u00fcster","year":"2006","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0185","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.ajpath.2015.01.021","article-title":"Characterization of the intrarenal renin-angiotensin system in experimental Alport syndrome","volume":"185","author":"Bae","year":"2015","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0190","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/S0002-9440(10)64802-X","article-title":"Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in Alport glomerular pathogenesis and serve as dual targets for metabolic therapy","volume":"157","author":"Cosgrove","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0195","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1681\/ASN.V122252","article-title":"Abnormal glomerular basement membrane laminins in murine, canine, and human Alport syndrome: aberrant laminin alpha2 deposition is species independent","volume":"12","author":"Kashtan","year":"2001","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0200","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/j.ajpath.2013.06.015","article-title":"\u03b11\u03b21 integrin\/Rac1-dependent mesangial invasion of glomerular capillaries in Alport syndrome","volume":"183","author":"Zallocchi","year":"2013","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0205","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1074\/jbc.M411130200","article-title":"Endothelin 1 induces beta 1Pix translocation and Cdc42 activation via protein kinase A-dependent pathway","volume":"280","author":"Chahdi","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2016.08.005_bb0210","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/S0960-9822(01)00506-1","article-title":"Cdc42 induces filopodia by promoting the formation of an IRSp53:mena complex","volume":"11","author":"Krugmann","year":"2001","journal-title":"Curr. Biol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0215","doi-asserted-by":"crossref","first-page":"6586","DOI":"10.1523\/JNEUROSCI.23-16-06586.2003","article-title":"Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis","volume":"23","author":"Takahashi","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.matbio.2016.08.005_bb0220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0099083","article-title":"Laminin \u03b12-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis","volume":"9","author":"Delimont","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.matbio.2016.08.005_bb0225","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1681\/ASN.2014111109","article-title":"Podocyte p53 limits the severity of experimental Alport syndrome","volume":"27","author":"Fukuda","year":"2016","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0230","doi-asserted-by":"crossref","first-page":"17117","DOI":"10.1073\/pnas.1114420108","article-title":"Tumor suppressor protein (p)53, is a regulator of NF-\u0138B repression by the glucocorticoid receptor","volume":"108","author":"Murphy","year":"2011","journal-title":"PNAS"},{"key":"10.1016\/j.matbio.2016.08.005_bb0235","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1046\/j.1523-1755.1999.00744.x","article-title":"Role for transforming growth factor-\u03b21 in Alport renal disease progression","volume":"56","author":"Sayers","year":"1999","journal-title":"Kidney Int."},{"key":"10.1016\/j.matbio.2016.08.005_bb0240","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.0030100","article-title":"Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease","volume":"3","author":"Zeisberg","year":"2006","journal-title":"PLoS Med."},{"key":"10.1016\/j.matbio.2016.08.005_bb0245","doi-asserted-by":"crossref","first-page":"32","DOI":"10.2353\/ajpath.2006.050896","article-title":"Role for macrophage metalloelastase in glomerular basement membrane damage associated with Alport syndrome","volume":"169","author":"Rao","year":"2006","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0250","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0002-9440(10)64541-5","article-title":"Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome","volume":"157","author":"Andrews","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0255","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1172\/JCI119431","article-title":"Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis","volume":"99","author":"Kalluri","year":"1997","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.matbio.2016.08.005_bb0260","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1681\/ASN.2007030328","article-title":"Laminin compensation in collagen alpha3(IV) knockout (Alport) glomeruli contributes to permeability defects","volume":"18","author":"Abrahamson","year":"2007","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0265","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1172\/JCI39569","article-title":"Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome","volume":"120","author":"Tanaka","year":"2010","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.matbio.2016.08.005_bb0270","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1681\/ASN.2006040377","article-title":"How does proteinuria cause progressive renal damage?","volume":"17","author":"Abbate","year":"2006","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0275","first-page":"F120","article-title":"Albumin contributes to kidney disease in Alport syndrome","volume":"311","author":"Jarad","year":"2016","journal-title":"Am. J. Phys. Renal Phys."},{"key":"10.1016\/j.matbio.2016.08.005_bb0280","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2353\/ajpath.2007.060158","article-title":"Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse","volume":"170","author":"Hahm","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0285","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1172\/JCI75852","article-title":"Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways","volume":"125","author":"Gomez","year":"2015","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.matbio.2016.08.005_bb0290","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1046\/j.1523-1755.2003.00871.x","article-title":"Monocytes may promote myofibroblast accumulation and apoptosis in Alport renal fibrosis","volume":"63","author":"Rodgers","year":"2003","journal-title":"Kidney Int."},{"key":"10.1016\/j.matbio.2016.08.005_bb0295","article-title":"Progression of Alport kidney disease in Col4a3 knock out mice is independent of sex or macrophage depletion by clodronate treatment","volume":"10","author":"Kim","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.matbio.2016.08.005_bb0300","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.2353\/ajpath.2010.100017","article-title":"Collagen XIII induced in vascular endothelium mediates alpha1beta1 integrin-dependent transmigration of monocytes in renal fibrosis","volume":"177","author":"Dennis","year":"2010","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0305","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1038\/labinvest.3700715","article-title":"Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease","volume":"88","author":"Lebleu","year":"2008","journal-title":"Lab. Investig."},{"key":"10.1016\/j.matbio.2016.08.005_bb0310","first-page":"21","article-title":"Adenovirus-mediated gene transfer into kidney glomeruli using an ex vivo and in vivo kidney perfusion system \u2013 first steps towards gene therapy of Alport syndrome","volume":"3","author":"Heikkila","year":"1996","journal-title":"Gene Ther."},{"key":"10.1016\/j.matbio.2016.08.005_bb0315","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/sj.gt.3301342","article-title":"Adenovirus-mediated transfer of type IV collagen alpha5 chain cDNA into swine kidney in vivo: deposition of the protein into the glomerular basement membrane","volume":"8","author":"Heikkil\u00e4","year":"2001","journal-title":"Gene Ther."},{"key":"10.1016\/j.matbio.2016.08.005_bb0320","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1016\/S0002-9440(10)63520-1","article-title":"A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3\u2212\/\u2212 Alport mice","volume":"163","author":"Heidet","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0325","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1681\/ASN.2013070798","article-title":"Feasibility of repairing glomerular basement membrane defects in Alport syndrome","volume":"25","author":"Lin","year":"2014","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0330","doi-asserted-by":"crossref","first-page":"7321","DOI":"10.1073\/pnas.0601436103","article-title":"Bone marrow derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease","volume":"103","author":"Sugimoto","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.matbio.2016.08.005_bb0335","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/sj.ki.5001521","article-title":"Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice","volume":"70","author":"Ninichuk","year":"2006","journal-title":"Kidney Int."},{"key":"10.1016\/j.matbio.2016.08.005_bb0340","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1681\/ASN.2011030243","article-title":"Injection of amniotic fluid stem cells delays progression of renal fibrosis","volume":"23","author":"Sedrakyan","year":"2012","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0345","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1681\/ASN.2009010123","article-title":"Stem cell therapies benefit Alport syndrome","volume":"20","author":"LeBleu","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.matbio.2016.08.005_bb0350","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1681\/ASN.V114649","article-title":"X-linked Alport syndrome: natural history of 195 families and genotype-phenotype correlations in males","volume":"11","author":"Jais","year":"2000","journal-title":"J. Am. Soc. Nephrol."}],"container-title":["Matrix Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0945053X16300713?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0945053X16300713?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T13:27:14Z","timestamp":1657200434000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0945053X16300713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":70,"alternative-id":["S0945053X16300713"],"URL":"https:\/\/doi.org\/10.1016\/j.matbio.2016.08.005","relation":{},"ISSN":["0945-053X"],"issn-type":[{"value":"0945-053X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome","name":"articletitle","label":"Article Title"},{"value":"Matrix Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.matbio.2016.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}