{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T08:06:38Z","timestamp":1792569998757,"version":"4.5.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,25]],"date-time":"2025-01-25T00:00:00Z","timestamp":1737763200000},"content-version":"am","delay-in-days":359,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["1R01AI136468\\u201301"],"award-info":[{"award-number":["1R01AI136468\\u201301"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["1R01AI130280"],"award-info":[{"award-number":["1R01AI130280"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["R01HL122895"],"award-info":[{"award-number":["R01HL122895"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["K08HL135266"],"award-info":[{"award-number":["K08HL135266"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["ES102605"],"award-info":[{"award-number":["ES102605"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["ES103342"],"award-info":[{"award-number":["ES103342"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["DP2 AI171150\\u201301"],"award-info":[{"award-number":["DP2 AI171150\\u201301"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007812","name":"University of Washington","doi-asserted-by":"publisher","award":["SINGH19R0"],"award-info":[{"award-number":["SINGH19R0"]}],"id":[{"id":"10.13039\/100007812","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007812","name":"University of Washington","doi-asserted-by":"publisher","award":["22277"],"award-info":[{"award-number":["22277"]}],"id":[{"id":"10.13039\/100007812","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012041","name":"Versus Arthritis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012041","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Matrix Biology"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.matbio.2024.01.004","type":"journal-article","created":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T12:16:42Z","timestamp":1705321002000},"page":"25-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Inter-alpha-trypsin inhibitor (I\u03b1I) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung"],"prefix":"10.1016","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8964-304X","authenticated-orcid":false,"given":"Fengying","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8552-6022","authenticated-orcid":false,"given":"Stephen R.","family":"Reeves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8284-9881","authenticated-orcid":false,"given":"Jourdan E.","family":"Brune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Y.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina K.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4675-1196","authenticated-orcid":false,"given":"Peter","family":"Waldron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8373-9828","authenticated-orcid":false,"given":"Sheona P.","family":"Drummond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline M.","family":"Milner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2171-1640","authenticated-orcid":false,"given":"Kimberly M.","family":"Alonge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4007-375X","authenticated-orcid":false,"given":"Stavros","family":"Garantziotis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1415-3134","authenticated-orcid":false,"given":"Anthony J.","family":"Day","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Altemeier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1037-3244","authenticated-orcid":false,"given":"Charles W.","family":"Frevert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.matbio.2024.01.004_bib0001","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a004903","article-title":"Overview of the matrisome\u2013an inventory of extracellular matrix constituents and functions","volume":"4","author":"Hynes","year":"2012","journal-title":"Cold. Spring. Harb. Perspect. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0002","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M111.014647","article-title":"The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices","volume":"11","author":"Naba","year":"2012","journal-title":"Mol. Cell Proteomics."},{"key":"10.1016\/j.matbio.2024.01.004_bib0003","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.matbio.2018.03.005","article-title":"Extracellular matrix in lung development, homeostasis and disease","volume":"73","author":"Zhou","year":"2018","journal-title":"Matrix. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0004","doi-asserted-by":"crossref","first-page":"342","DOI":"10.3390\/cells8040342","article-title":"Extracellular matrix component remodeling in respiratory diseases: what has been found in clinical and experimental studies?","volume":"8","author":"Ito","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.matbio.2024.01.004_bib0005","doi-asserted-by":"crossref","first-page":"512","DOI":"10.3389\/fimmu.2020.00512","article-title":"Versican\u2014A critical extracellular matrix regulator of immunity and inflammation","volume":"11","author":"Wight","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0006","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/s41586-020-2877-5","article-title":"Exuberant fibroblast activity compromises lung function via ADAMTS4","volume":"587","author":"Boyd","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.matbio.2024.01.004_bib0007","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.4049\/jimmunol.0903274","article-title":"Kinetics of Chemokine-Glycosaminoglycan Interactions Control Neutrophil Migration into the Airspaces of the Lungs","volume":"184","author":"Tanino","year":"2010","journal-title":"Journal of Immunology"},{"key":"10.1016\/j.matbio.2024.01.004_bib0008","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1165\/rcmb.2011-0294OC","article-title":"Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide","volume":"47","author":"Tanino","year":"2012","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0009","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.matbio.2016.12.001","article-title":"Provisional matrix: a role for versican and hyaluronan","volume":"60-61","author":"Wight","year":"2017","journal-title":"Matrix. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0010","doi-asserted-by":"crossref","first-page":"L1069","DOI":"10.1152\/ajplung.00353.2017","article-title":"Versican is produced by Trif- and type I interferon-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs","volume":"313","author":"Chang","year":"2017","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.matbio.2014.01.011","article-title":"A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease","volume":"34","author":"Chang","year":"2014","journal-title":"Matrix. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0012","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1369\/0022155417751880","article-title":"Proteoglycans as Immunomodulators of the Innate Immune Response to Lung Infection","volume":"66","author":"Kang","year":"2018","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0013","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1074\/jbc.M116.753186","article-title":"Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation","volume":"292","author":"Kang","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0014","first-page":"78","article-title":"Hyaluronan biology: a complex balancing act of structure, function, location and context","volume":"1-10","author":"Garantziotis","year":"2019","journal-title":"Matrix. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0015","first-page":"78","article-title":"Hyaluronan interactions with innate immunity in lung biology","volume":"84-99","author":"Tighe","year":"2019","journal-title":"Matrix. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0016","doi-asserted-by":"crossref","first-page":"C1037","DOI":"10.1152\/ajpcell.00071.2022","article-title":"The role of hyaluronan synthesis and degradation in the critical respiratory illness COVID-19","volume":"322","author":"Albtoush","year":"2022","journal-title":"Am. J. Physiol.-Cell Physiol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0017","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/712507","article-title":"The rise and fall of hyaluronan in respiratory diseases","volume":"2015","author":"Lauer","year":"2015","journal-title":"Int. J. Cell Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0018","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/glycob\/cws122","article-title":"Correlation of hyaluronan deposition with infiltration of eosinophils and lymphocytes in a cockroach-induced murine model of asthma","volume":"23","author":"Cheng","year":"2013","journal-title":"Glycobiology"},{"key":"10.1016\/j.matbio.2024.01.004_bib0019","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.matbio.2018.06.006","article-title":"Defective lung function following influenza virus is due to prolonged, reversible hyaluronan synthesis","volume":"80","author":"Bell","year":"2019","journal-title":"Matrix. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cellimm.2016.12.003","article-title":"Interplay of extracellular matrix and leukocytes in lung inflammation","volume":"312","author":"Wight","year":"2017","journal-title":"Cell Immunol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0021","doi-asserted-by":"crossref","DOI":"10.1369\/0022155420940067","article-title":"The inter-alpha-trypsin inhibitor family: versatile molecules in biology and pathology","author":"Lord","year":"2020","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0022","doi-asserted-by":"crossref","first-page":"23124","DOI":"10.1074\/jbc.M115.663823","article-title":"Hyaluronan and its heavy chain modification in asthma severity and experimental asthma exacerbation","volume":"290","author":"Lauer","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0023","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1165\/rcmb.2006-0018OC","article-title":"TSG-6 potentiates the antitissue kallikrein activity of inter\u2013\u03b1-inhibitor through bikunin release","volume":"36","author":"Forteza","year":"2007","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0024","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/978-1-4939-1714-3_42","article-title":"Analysis of the heavy-chain modification and TSG-6 activity in pathological hyaluronan matrices","volume":"1229","author":"Lauer","year":"2015","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0025","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1242\/jcs.00407","article-title":"TSG-6: a multifunctional protein associated with inflammation","volume":"116","author":"Milner","year":"2003","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.matbio.2024.01.004_bib0026","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.matbio.2018.01.011","article-title":"TSG-6: a multifunctional protein with anti-inflammatory and tissue-protective properties","volume":"78-79","author":"Day","year":"2019","journal-title":"Matrix. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0027","doi-asserted-by":"crossref","first-page":"25674","DOI":"10.1074\/jbc.M501332200","article-title":"Characterization of complexes formed between tsg-6 andinter-\u03b1-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan","volume":"280","author":"Rugg","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0028","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1167\/iovs.13-13094","article-title":"In vivo downregulation of innate and adaptive immune responses in corneal allograft rejection by HC-HA\/PTX3 complex purified from amniotic membrane","volume":"55","author":"He","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.matbio.2024.01.004_bib0029","doi-asserted-by":"crossref","first-page":"25792","DOI":"10.1074\/jbc.M113.479584","article-title":"Immobilized heavy chain-hyaluronic acid polarizes lipopolysaccharide-activated macrophages toward M2 phenotype","volume":"288","author":"He","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0030","doi-asserted-by":"crossref","first-page":"42195","DOI":"10.1038\/srep42195","article-title":"Heavy Chain-Hyaluronan\/Pentraxin 3 from Amniotic Membrane Suppresses Inflammation and Scarring in Murine Lacrimal Gland and Conjunctiva of Chronic Graft-versus-Host Disease","volume":"7","author":"Ogawa","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.matbio.2024.01.004_bib0031","doi-asserted-by":"crossref","first-page":"13531","DOI":"10.1074\/jbc.M113.525287","article-title":"Constitutive expression of pentraxin 3 (PTX3) protein by human amniotic membrane cells leads to formation of the heavy chain (HC)-hyaluronan (HA)-PTX3 complex","volume":"289","author":"Zhang","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0032","doi-asserted-by":"crossref","first-page":"20136","DOI":"10.1074\/jbc.M109.021881","article-title":"Biochemical characterization and function of complexes formed by hyaluronan and the heavy chains of inter-\u03b1-inhibitor (HC\u00b7 HA) purified from extracts of human amniotic membrane","volume":"284","author":"He","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0033","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1159\/000314362","article-title":"Deficiency in the serum-derived hyaluronan-associated protein-hyaluronan complex enhances airway hyperresponsiveness in a murine model of asthma","volume":"153","author":"Zhu","year":"2010","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.matbio.2023.06.007","article-title":"7TSG6 hyaluronan matrix remodeling dampens the inflammatory response during colitis","author":"Albtoush","year":"2023","journal-title":"Matrix Biology"},{"key":"10.1016\/j.matbio.2024.01.004_bib0035","doi-asserted-by":"crossref","first-page":"5313","DOI":"10.1074\/jbc.M807979200","article-title":"Airway Smooth Muscle Cells Synthesize Hyaluronan Cable Structures Independent of Inter-\u03b1-inhibitor Heavy Chain Attachment*","volume":"284","author":"Lauer","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0036","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/jcb.240630503","article-title":"T-Cell lymphoma cell lines (HUT102 and HUT78) established at the National Cancer Institute: history and importance to understanding the biology, clinical features, and therapy of cutaneous T-cell lymphomas (CTCL) and adult T-cell leukemia-lymphomas (ATLL)","volume":"63","author":"Bunn Jr","year":"1996","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0037","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/S1357-2725(02)00010-9","article-title":"Differentiated HL-60 cells are a valid model system for the analysis of human neutrophil migration and chemotaxis","volume":"34","author":"Hauert","year":"2002","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0038","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1074\/jbc.M112.389882","article-title":"Tumor necrosis factor-stimulated gene-6 (TSG-6) amplifies hyaluronan synthesis by airway smooth muscle cells","volume":"288","author":"Lauer","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0039","doi-asserted-by":"crossref","first-page":"7693","DOI":"10.1074\/jbc.C000899200","article-title":"Defect in SHAP-hyaluronan complex causes severe female infertility: a study by inactivation of the bikunin gene in mice","volume":"276","author":"Zhuo","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0040","doi-asserted-by":"crossref","first-page":"20303","DOI":"10.1074\/jbc.M506703200","article-title":"SHAP potentiates the CD44-mediated leukocyte adhesion to the hyaluronan substratum","volume":"281","author":"Zhuo","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0041","doi-asserted-by":"crossref","first-page":"29642","DOI":"10.1074\/jbc.M113.477422","article-title":"Inter-alpha-inhibitor impairs TSG-6-induced hyaluronan cross-linking","volume":"288","author":"Baranova","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0042","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1369\/00221554211054447","article-title":"Type I Interferon Signaling Increases Versican Expression and Synthesis in Lung Stromal Cells During Influenza Infection","volume":"69","author":"Brune","year":"2021","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0043","doi-asserted-by":"crossref","DOI":"10.1152\/ajplung.00317.2022","article-title":"Multi-Compartmental Analysis of the Murine Pulmonary Immune Response by Spectral Flow Cytometry","author":"Chang","year":"2023","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0044","doi-asserted-by":"crossref","first-page":"24324","DOI":"10.1074\/jbc.M116.755660","article-title":"Thrombin Cleavage of Inter-\u03b1-inhibitor Heavy Chain 1 Regulates Leukocyte Binding to an Inflammatory Hyaluronan Matrix","volume":"291","author":"Petrey","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0045","doi-asserted-by":"crossref","first-page":"5278","DOI":"10.1074\/jbc.RA119.011916","article-title":"Inter-\u03b1-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation","volume":"295","author":"Briggs","year":"2020","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0046","doi-asserted-by":"crossref","first-page":"16922","DOI":"10.1074\/jbc.M808560200","article-title":"Inter-\u03b1-trypsin inhibitor promotes bronchial epithelial repair after injury through vitronectin binding","volume":"284","author":"Adair","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0047","doi-asserted-by":"crossref","first-page":"30481","DOI":"10.1074\/jbc.M114.568154","article-title":"Incorporation of pentraxin 3 into hyaluronan matrices is tightly regulated and promotes matrix cross-linking","volume":"289","author":"Baranova","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0048","doi-asserted-by":"crossref","first-page":"22930","DOI":"10.1074\/jbc.M112.404186","article-title":"Sulfation of the bikunin chondroitin sulfate chain determines heavy chain\u00b7 hyaluronan complex formation","volume":"288","author":"Lord","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0049","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0300-9084(03)00066-X","article-title":"In acute inflammation, the chondroitin-4 sulphate carried by bikunin is not only longer; it is also undersulphated","volume":"85","author":"Capon","year":"2003","journal-title":"Biochimie"},{"key":"10.1016\/j.matbio.2024.01.004_bib0050","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1152\/physrev.00032.2017","article-title":"Integrative physiology of pneumonia","volume":"98","author":"Quinton","year":"2018","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.matbio.2024.01.004_bib0051","doi-asserted-by":"crossref","first-page":"11309","DOI":"10.1074\/jbc.M802400200","article-title":"Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice","volume":"284","author":"Garantziotis","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0052","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12931-018-0812-1","article-title":"Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury","volume":"19","author":"Ni","year":"2018","journal-title":"Respir. Res."},{"key":"10.1016\/j.matbio.2024.01.004_bib0053","first-page":"155","article-title":"Resolution of Lung Inflammation by CD44","volume":"296","author":"Teder","year":"2002","journal-title":"Science (1979)"},{"key":"10.1016\/j.matbio.2024.01.004_bib0054","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12931-020-01610-x","article-title":"Inhaled high molecular weight hyaluronan ameliorates respiratory failure in acute COPD exacerbation: a pilot study","volume":"22","author":"Galdi","year":"2021","journal-title":"Respir. Res."},{"issue":"123","key":"10.1016\/j.matbio.2024.01.004_bib0055","article-title":"Effects of inhaled high-molecular weight hyaluronan in inflammatory airway disease","volume":"17","author":"Lamas","year":"2016","journal-title":"Respir. Res."},{"key":"10.1016\/j.matbio.2024.01.004_bib0056","doi-asserted-by":"crossref","first-page":"L787","DOI":"10.1152\/ajplung.00009.2018","article-title":"High molecular weight hyaluronan ameliorates allergic inflammation and airway hyperresponsiveness in the mouse","volume":"315","author":"Johnson","year":"2018","journal-title":"Am. J. Physiol.-Lung Cellular Mol. Physiol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0057","doi-asserted-by":"crossref","first-page":"25085","DOI":"10.1074\/jbc.274.35.25085","article-title":"Three Isoforms of Mammalian Hyaluronan Synthases Have Distinct Enzymatic Properties*","volume":"274","author":"Itano","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0058","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1084\/jem.20071765","article-title":"Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoids","volume":"205","author":"McDonald","year":"2008","journal-title":"J. Experimental Med."},{"key":"10.1016\/j.matbio.2024.01.004_bib0059","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2015.00150","article-title":"The Where, When, How, and Why of Hyaluronan Binding by Immune Cells","volume":"6","author":"Lee-Sayer","year":"2015","journal-title":"Front. Immunol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0060","doi-asserted-by":"crossref","first-page":"6184","DOI":"10.4049\/jimmunol.159.12.6184","article-title":"Cytokine induction of the ability of human monocyte CD44 to bind hyaluronan is mediated primarily by TNF-alpha and is inhibited by IL-4 and IL-13","volume":"159","author":"Levesque","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0061","doi-asserted-by":"crossref","first-page":"25675","DOI":"10.1074\/jbc.M111.247395","article-title":"The inflammation-associated protein TSG-6 cross-links hyaluronan via hyaluronan-induced TSG-6 oligomers","volume":"286","author":"Baranova","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0062","doi-asserted-by":"crossref","first-page":"25745","DOI":"10.1074\/jbc.M313319200","article-title":"TSG-6 modulates the interaction between hyaluronan and cell surface CD44","volume":"279","author":"Lesley","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0063","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.sbi.2017.12.002","article-title":"Glycosaminoglycans in extracellular matrix organisation: are concepts from soft matter physics key to understanding the formation of perineuronal nets?","volume":"50","author":"Richter","year":"2018","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0064","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.3390\/ijms21093075","article-title":"On top of the alveolar epithelium: surfactant and the glycocalyx","volume":"21","author":"Ochs","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.matbio.2024.01.004_bib0065","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1095\/biolreprod65.1.301","article-title":"TSG-6 is concentrated in the extracellular matrix of mouse cumulus oocyte complexes through hyaluronan and inter-alpha-inhibitor binding","volume":"65","author":"Carrette","year":"2001","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.matbio.2024.01.004_bib0066","doi-asserted-by":"crossref","first-page":"28708","DOI":"10.1074\/jbc.M115.669838","article-title":"Metal ion-dependent heavy chain transfer activity of TSG-6 mediates assembly of the cumulus-oocyte matrix","volume":"290","author":"Briggs","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0067","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1093\/glycob\/cwz060","article-title":"Quantitative analysis of chondroitin sulfate disaccharides from human and rodent fixed brain tissue by electrospray ionization-tandem mass spectrometry","volume":"29","author":"Alonge","year":"2019","journal-title":"Glycobiology"},{"key":"10.1016\/j.matbio.2024.01.004_bib0068","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1369\/0022155420959146","article-title":"The Use of Quantitative Digital Pathology to Measure Proteoglycan and Glycosaminoglycan Expression and Accumulation in Healthy and Diseased Tissues","volume":"69","author":"Davis","year":"2021","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.matbio.2024.01.004_bib0069","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3233\/JAD-180797","article-title":"Increased hyaluronan and TSG-6 in association with neuropathologic changes of Alzheimer's disease","volume":"67","author":"Reed","year":"2019","journal-title":"J. Alzheimer's Dis."},{"key":"10.1016\/j.matbio.2024.01.004_bib0070","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1165\/rcmb.2003-0380OC","article-title":"Pro- and anti-inflammatory factors cooperate to control hyaluronan synthesis in lung fibroblasts","volume":"31","author":"Wilkinson","year":"2004","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.matbio.2024.01.004_bib0071","series-title":"Lung Innate Immunity and Inflammation: Methods and Protocols","first-page":"59","article-title":"Isolation and characterization of mouse fibroblasts","author":"Edelman","year":"2018"},{"key":"10.1016\/j.matbio.2024.01.004_bib0072","doi-asserted-by":"crossref","first-page":"3159","DOI":"10.3389\/fimmu.2019.03159","article-title":"Respiratory syncytial virus infection of human lung fibroblasts induces a hyaluronan-enriched extracellular matrix that binds mast cells and enhances expression of mast cell proteases","volume":"10","author":"Reeves","year":"2019","journal-title":"Front. Immunol."}],"container-title":["Matrix Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0945053X24000040?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0945053X24000040?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T16:10:06Z","timestamp":1778515806000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0945053X24000040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":72,"alternative-id":["S0945053X24000040"],"URL":"https:\/\/doi.org\/10.1016\/j.matbio.2024.01.004","relation":{},"ISSN":["0945-053X"],"issn-type":[{"value":"0945-053X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inter-alpha-trypsin inhibitor (I\u03b1I) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung","name":"articletitle","label":"Article Title"},{"value":"Matrix Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.matbio.2024.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}