{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:16:29Z","timestamp":1792034189010,"version":"4.4.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["TRR 359"],"award-info":[{"award-number":["TRR 359"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["CRC1453"],"award-info":[{"award-number":["CRC1453"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["259373024-Z01"],"award-info":[{"award-number":["259373024-Z01"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["CRC1479"],"award-info":[{"award-number":["CRC1479"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["431984000 \\u2013 S1"],"award-info":[{"award-number":["431984000 \\u2013 S1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["491676693-Z01"],"award-info":[{"award-number":["491676693-Z01"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["TRR167"],"award-info":[{"award-number":["TRR167"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["CRC 1160"],"award-info":[{"award-number":["CRC 1160"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["256073931-Z02"],"award-info":[{"award-number":["256073931-Z02"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["441891347-S1"],"award-info":[{"award-number":["441891347-S1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["202208080205"],"award-info":[{"award-number":["202208080205"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021729","name":"University of Freiburg Faculty of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021729","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["FKZ 01ZZ2322A"],"award-info":[{"award-number":["FKZ 01ZZ2322A"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Matrix Biology"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.matbio.2024.11.005","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T09:18:45Z","timestamp":1732785525000},"page":"12-23","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: A gene expression study"],"prefix":"10.1016","volume":"135","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5296-6312","authenticated-orcid":false,"given":"Yao","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Elena","family":"Hess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7379-9699","authenticated-orcid":false,"given":"Philipp R.","family":"Esser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4666-2240","authenticated-orcid":false,"given":"Alexander","family":"Nystr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3670-0602","authenticated-orcid":false,"given":"Melanie","family":"Boerries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saliha Beyza","family":"Sayar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Has","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.matbio.2024.11.005_bib0001","series-title":"Curr. Top. Membr.","first-page":"117","article-title":"Epidermal basement membrane in health and disease","author":"Has","year":"2015"},{"key":"10.1016\/j.matbio.2024.11.005_bib0002","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1111\/bjd.18921","article-title":"Consensus reclassification of inherited epidermolysis bullosa and other disorders with skin fragility","volume":"183","author":"Has","year":"2020","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0003","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.matbio.2018.04.001","article-title":"Epidermolysis bullosa: Molecular pathology of connective tissue components in the cutaneous basement membrane zone","volume":"71\u201372","author":"Has","year":"2018","journal-title":"Matrix Biol"},{"key":"10.1016\/j.matbio.2024.11.005_bib0004","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1111\/j.1365-2133.2004.06206.x","article-title":"Intracellular degradation of \u03b24 integrin in lethal junctional epidermolysis bullosa with pyloric atresia","volume":"151","author":"Micheloni","year":"2004","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0005","doi-asserted-by":"crossref","first-page":"135","DOI":"10.4161\/cam.22418","article-title":"Laminin 332 in junctional epidermolysis bullosa","volume":"7","author":"Kiritsi","year":"2013","journal-title":"Cell Adhes. Migr."},{"key":"10.1016\/j.matbio.2024.11.005_bib0006","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/hmg\/ddw404","article-title":"Amino acid duplication in the coiled-coil structure of collagen XVII alters its maturation and trimerization causing mild junctional epidermolysis bullosa","volume":"26","author":"Kroeger","year":"2017","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.matbio.2024.11.005_bib0007","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.259004","article-title":"Regulation of hemidesmosome dynamics and cell signaling by integrin \u03b16\u03b24","volume":"134","author":"Molder","year":"2021","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.matbio.2024.11.005_bib0008","doi-asserted-by":"crossref","first-page":"e87263","DOI":"10.1371\/journal.pone.0087263","article-title":"Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K\/Rac1 signaling","volume":"9","author":"L\u00f6ffek","year":"2014","journal-title":"PLOS One"},{"key":"10.1016\/j.matbio.2024.11.005_bib0009","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.jid.2016.01.012","article-title":"Collagen XVII shedding suppresses Re-epithelialization by directing keratinocyte migration and dampening mTOR signaling","volume":"136","author":"Jack\u00f3w","year":"2016","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0010","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.jid.2015.10.060","article-title":"Generation of a functional non-shedding collagen XVII mouse model: relevance of collagen xvii shedding in wound healing","volume":"136","author":"Jack\u00f3w","year":"2016","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0011","doi-asserted-by":"crossref","first-page":"C1308","DOI":"10.1152\/ajpcell.00128.2024","article-title":"Roles for epithelial integrin \u03b13\u03b21 in regulation of the microenvironment during normal and pathological tissue remodeling","volume":"326","author":"Miskin","year":"2024","journal-title":"Am. J. Physiol.-Cell Physiol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0012","doi-asserted-by":"crossref","DOI":"10.1002\/bies.202000119","article-title":"Crosstalk between cell adhesion complexes in regulation of mechanotransduction","volume":"42","author":"Zuidema","year":"2020","journal-title":"BioEssays"},{"key":"10.1016\/j.matbio.2024.11.005_bib0013","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.matbio.2005.12.001","article-title":"Ligand-binding specificities of laminin-binding integrins: A comprehensive survey of laminin\u2013integrin interactions using recombinant \u03b13\u03b21, \u03b16\u03b21, \u03b17\u03b21 and \u03b16\u03b24 integrins","volume":"25","author":"Nishiuchi","year":"2006","journal-title":"Matrix Biol"},{"key":"10.1016\/j.matbio.2024.11.005_bib0014","first-page":"1","article-title":"Hemidesmosomes and focal contact proteins: Functions and cross-talk in keratinocytes, bullous diseases and wound healing","volume":"62","author":"Tsuruta","year":"2011","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.matbio.2024.11.005_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jid.2019.03.1139","article-title":"Hemidesmosomes and focal adhesions treadmill as separate but linked entities during keratinocyte migration","volume":"139","author":"Pora","year":"2019","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0016","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1038\/jid.2009.439","article-title":"Dynamic relationship of focal contacts and hemidesmosome protein complexes in live cells","volume":"130","author":"Ozawa","year":"2010","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0017","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.matbio.2018.07.001","article-title":"Constitutional absence of epithelial integrin \u03b13 impacts the composition of the cellular microenvironment of ILNEB keratinocytes","volume":"74","author":"He","year":"2018","journal-title":"Matrix Biol"},{"key":"10.1016\/j.matbio.2024.11.005_bib0018","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.201904137","article-title":"Hemidesmosomes modulate force generation via focal adhesions","volume":"219","author":"Wang","year":"2020","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0019","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s00441-016-2446-2","article-title":"Integrin-mediated regulation of epidermal wound functions","volume":"365","author":"DiPersio","year":"2016","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.matbio.2024.11.005_bib0020","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.jdin.2023.02.016","article-title":"Mapping the burden of severe forms of epidermolysis bullosa \u2013 Implications for patient management","volume":"11","author":"Mellerio","year":"2023","journal-title":"JAAD Int"},{"key":"10.1016\/j.matbio.2024.11.005_bib0021","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1093\/ced\/llad012","article-title":"Interleukin-17A immune pattern across genetic acantholytic and blistering disorders","volume":"48","author":"Haghighi Javid","year":"2023","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0022","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/cup.12521","article-title":"Dermal eosinophilic infiltrate in junctional epidermolysis bullosa","volume":"42","author":"Saraiya","year":"2015","journal-title":"J. Cutan. Pathol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0023","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1016\/j.jid.2017.07.002","article-title":"Pro-Inflammatory Chemokines And Cytokines Dominate The Blister Fluid Molecular Signature In Patients With Epidermolysis Bullosa And Affect Leukocyte And Stem Cell Migration","volume":"137","author":"Alexeev","year":"2017","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0024","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1111\/jdv.14673","article-title":"Immune response patterns in non-communicable inflammatory skin diseases","volume":"32","author":"Eyerich","year":"2018","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2019.04.055","article-title":"Laminin 332-Dependent YAP dysregulation depletes epidermal stem cells in junctional epidermolysis bullosa","volume":"27","author":"De Rosa","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.matbio.2024.11.005_bib0026","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/j.ymthe.2020.03.006","article-title":"Gentamicin induces Laminin 332 and improves wound healing in junctional epidermolysis bullosa patients with nonsense mutations","volume":"28","author":"Kwong","year":"2020","journal-title":"Mol. Ther."},{"key":"10.1016\/j.matbio.2024.11.005_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.jid.2021.09.018","article-title":"Read-through for nonsense mutations in Type XVII collagen\u2012deficient junctional epidermolysis bullosa","volume":"142","author":"Has","year":"2022","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0028","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: kyoto encyclopedia of genes and genomes","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.matbio.2024.11.005_bib0029","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1091\/mbc.e09-01-0051","article-title":"BPAG1e maintains keratinocyte polarity through \u03b24 integrin\u2013mediated modulation of Rac 1 and cofilin activities","volume":"20","author":"Hamill","year":"2009","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.matbio.2024.11.005_bib0030","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1038\/s41467-018-04978-z","article-title":"From the betweenness centrality in street networks to structural invariants in random planar graphs","volume":"9","author":"Kirkley","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.matbio.2024.11.005_bib0031","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.addr.2020.09.005","article-title":"Fibronectin in development and wound healing","volume":"170","author":"Patten","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.matbio.2024.11.005_bib0032","doi-asserted-by":"crossref","first-page":"4062","DOI":"10.3390\/ijms22084062","article-title":"Thrombospondin-1 CD47 signalling: from mechanisms to medicine","volume":"22","author":"Kale","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.matbio.2024.11.005_bib0033","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0945-053X(98)90083-X","article-title":"Tenascin-C expression in human epidermal keratinocytes is regulated by inflammatory cytokines and a stress response pathway","volume":"17","author":"Latijnhouwers","year":"1998","journal-title":"Matrix Biol"},{"key":"10.1016\/j.matbio.2024.11.005_bib0034","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1177\/43.2.7529785","article-title":"Expression of proteoglycans and hyaluronan during wound healing","volume":"43","author":"Oksala","year":"1995","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.matbio.2024.11.005_bib0035","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00441-014-2064-9","article-title":"Integrin-mediated adhesion and mechano-sensing in cutaneous wound healing","volume":"360","author":"Kenny","year":"2015","journal-title":"Cell Tissue Res"},{"key":"10.1016\/j.matbio.2024.11.005_bib0036","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/nrm1004","article-title":"CD44: From adhesion molecules to signalling regulators","volume":"4","author":"Ponta","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0037","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/nri2622","article-title":"Skin immune sentinels in health and disease","volume":"9","author":"Nestle","year":"2009","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0038","doi-asserted-by":"crossref","first-page":"389","DOI":"10.18632\/aging.100755","article-title":"Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin aging","volume":"7","author":"Breitenbach","year":"2015","journal-title":"Aging"},{"key":"10.1016\/j.matbio.2024.11.005_bib0039","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1111\/jcmm.17948","article-title":"Conditional knockout of ITGB4 in bronchial epithelial cells directs bronchopulmonary dysplasia","volume":"27","author":"Chen","year":"2023","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.matbio.2024.11.005_bib0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.jid.2021.04.008","article-title":"Laminin 332 is indispensable for homeostatic epidermal differentiation programs","volume":"141","author":"Tayem","year":"2021","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0041","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.matbio.2017.04.003","article-title":"The provisional matrix: setting the stage for tissue repair outcomes","volume":"60\u201361","author":"Barker","year":"2017","journal-title":"Matrix Biol"},{"key":"10.1016\/j.matbio.2024.11.005_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.104130","article-title":"Single-cell RNA sequencing identifies a migratory keratinocyte subpopulation expressing THBS1 in epidermal wound healing","volume":"25","author":"Siriwach","year":"2022","journal-title":"iScience"},{"key":"10.1016\/j.matbio.2024.11.005_bib0043","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.3390\/biom12111689","article-title":"Tenascin-C: a key regulator in angiogenesis during wound healing","volume":"12","author":"Wang","year":"2022","journal-title":"Biomolecules"},{"key":"10.1016\/j.matbio.2024.11.005_bib0044","doi-asserted-by":"crossref","DOI":"10.1016\/j.jid.2020.10.024","article-title":"Diversity of mechanisms underlying latent TGF-\u03b2 activation in recessive dystrophic epidermolysis bullosa","volume":"141","author":"Akasaka","year":"2021","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0045","doi-asserted-by":"crossref","first-page":"djv293","DOI":"10.1093\/jnci\/djv293","article-title":"Suppression of TGF\u03b2 and angiogenesis by Type VII collagen in cutaneous SCC","volume":"108","author":"Martins","year":"2016","journal-title":"JNCI J. Natl. Cancer Inst."},{"key":"10.1016\/j.matbio.2024.11.005_bib0046","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.matbio.2024.07.005","article-title":"Skeletal pathology in mouse models of Gould syndrome is partially alleviated by genetically reducing TGF\u03b2 signaling","volume":"133","author":"Labelle-Dumais","year":"2024","journal-title":"Matrix Biol"},{"key":"10.1016\/j.matbio.2024.11.005_bib0047","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1016\/j.jid.2019.04.010","article-title":"Cross-talk between hemidesmosomes and focal adhesions: a primer for wound healing, blistering skin disease, and skin aging","volume":"139","author":"Hatzfeld","year":"2019","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0048","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.260987","article-title":"Mechanotransduction through hemidesmosomes during aging and longevity","volume":"136","author":"Ewald","year":"2023","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.matbio.2024.11.005_bib0049","doi-asserted-by":"crossref","first-page":"792","DOI":"10.3390\/ijms23020792","article-title":"CXCL1: gene, promoter, regulation of expression, mRNA stability, regulation of activity in the intercellular space","volume":"23","author":"Korbecki","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.matbio.2024.11.005_bib0050","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1586\/1744666X.2014.894886","article-title":"The CXCL8\/IL-8 chemokine family and its receptors in inflammatory diseases","volume":"10","author":"Russo","year":"2014","journal-title":"Exp.ert Rev. Clin. Immunol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0051","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/nri3399","article-title":"Neutrophil recruitment and function in health and inflammation","volume":"13","author":"Kolaczkowska","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.matbio.2024.11.005_bib0052","doi-asserted-by":"crossref","first-page":"16529","DOI":"10.1038\/srep16529","article-title":"Role of integrin \u03b24 in lung endothelial cell inflammatory responses to mechanical stress","volume":"5","author":"Chen","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.matbio.2024.11.005_bib0053","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/5842677","article-title":"Shear-Induced ITGB4 Promotes Endothelial Cell Inflammation and Atherosclerosis","volume":"2022","author":"Kong","year":"2022","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.matbio.2024.11.005_bib0054","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.7150\/ijbs.65174","article-title":"Integrin-\u03b24 regulates the dynamic changes of phenotypic characteristics in association with epithelial-mesenchymal transition (EMT) and RhoA activity in airway epithelial cells during injury and repair","volume":"18","author":"Tan","year":"2022","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.matbio.2024.11.005_bib0055","doi-asserted-by":"crossref","first-page":"6434","DOI":"10.1073\/pnas.1721805115","article-title":"BP180 dysfunction triggers spontaneous skin inflammation in mice","volume":"115","author":"Zhang","year":"2018","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.matbio.2024.11.005_bib0056","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.immuni.2015.01.014","article-title":"Structural damage in the C. Elegans epidermis causes release of STA-2 and induction of an innate immune response","volume":"42","author":"Zhang","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.matbio.2024.11.005_bib0057","doi-asserted-by":"crossref","first-page":"19798","DOI":"10.1074\/jbc.M300513200","article-title":"Regulation of interleukin-1\u03b1 expression by integrins and epidermal growth factor receptor in keratinocytes from a mouse model of inflammatory skin disease*","volume":"278","author":"Hobbs","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.matbio.2024.11.005_bib0058","doi-asserted-by":"crossref","DOI":"10.1016\/j.devcel.2024.04.015","article-title":"Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling","volume":"59","author":"Ren","year":"2024","journal-title":"Dev. Cell"},{"key":"10.1016\/j.matbio.2024.11.005_bib0059","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.matbio.2024.11.005_bib0060","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.matbio.2024.11.005_bib0061","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.matbio.2024.11.005_bib0062","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1186\/1471-2105-10-161","article-title":"GAGE: generally applicable gene set enrichment for pathway analysis","volume":"10","author":"Luo","year":"2009","journal-title":"BMC Bioinfor.matics"},{"key":"10.1016\/j.matbio.2024.11.005_bib0063","series-title":"Data Analysis","first-page":"189","article-title":"Ggplot2 elegant graph","author":"Wickham","year":"2016"},{"key":"10.1016\/j.matbio.2024.11.005_bib0064","doi-asserted-by":"crossref","first-page":"15321","DOI":"10.1038\/ncomms15321","article-title":"YAP regulates cell mechanics by controlling focal adhesion assembly","volume":"8","author":"Nardone","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.matbio.2024.11.005_bib0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.mbplus.2022.100119","article-title":"Integrin \u03b13 negative podocytes: A gene expression study","volume":"16","author":"Frommherz","year":"2022","journal-title":"Matrix Biol. Plus"},{"key":"10.1016\/j.matbio.2024.11.005_bib0066","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1242\/jcs.01689","article-title":"Keratinocytes display normal proliferation, survival and differentiation in conditional \u03b24-integrin knockout mice","volume":"118","author":"Raymond","year":"2005","journal-title":"J. Cell Sci."}],"container-title":["Matrix Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0945053X24001410?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0945053X24001410?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T04:21:02Z","timestamp":1778559662000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0945053X24001410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":66,"alternative-id":["S0945053X24001410"],"URL":"https:\/\/doi.org\/10.1016\/j.matbio.2024.11.005","relation":{},"ISSN":["0945-053X"],"issn-type":[{"value":"0945-053X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alterations in the microenvironment of junctional epidermolysis bullosa keratinocytes: A gene expression study","name":"articletitle","label":"Article Title"},{"value":"Matrix Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.matbio.2024.11.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}