{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T20:19:55Z","timestamp":1793823595920,"version":"4.6.1"},"reference-count":86,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:00:00Z","timestamp":1759881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006668","name":"Oregon Health and Science University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R00DE028876"],"award-info":[{"award-number":["R00DE028876"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Materials &amp; Design"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.matdes.2025.114910","type":"journal-article","created":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:24:26Z","timestamp":1760145866000},"page":"114910","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Assessment of physicochemical properties and biological responses of chemically surface-modified microcapsules for self-healing dental restorative materials"],"prefix":"10.1016","volume":"259","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8254-1956","authenticated-orcid":false,"given":"Jo\u00e3o Marcos","family":"Batista","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivashankari","family":"Rajasekaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao","family":"Huynh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tapas","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Eduarda","family":"Marinho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2851-3687","authenticated-orcid":false,"given":"Jesse","family":"Corcoran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rio Alexandre Coelho","family":"Sinhoreti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Paula Piovezan","family":"Fugolin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.matdes.2025.114910_b0005","doi-asserted-by":"crossref","DOI":"10.3390\/jfb15070173","article-title":"A historical perspective on dental composite restorative materials","volume":"15","author":"Ferracane","year":"2024","journal-title":"J. Funct. Biomater."},{"issue":"5","key":"10.1016\/j.matdes.2025.114910_b0010","first-page":"311","article-title":"Advances in restorative resin-based composites: a review","volume":"47","author":"Rawls","year":"2019","journal-title":"J. Calif. Dent. Assoc."},{"key":"10.1016\/j.matdes.2025.114910_b0015","doi-asserted-by":"crossref","DOI":"10.3390\/dj12090291","article-title":"Multifactorial contributors to the longevity of dental restorations: an integrated review of related factors","author":"Santos","year":"2024","journal-title":"Dent. J."},{"key":"10.1016\/j.matdes.2025.114910_b0020","doi-asserted-by":"crossref","DOI":"10.3390\/bioengineering10121354","article-title":"Teeth microcracks research: towards multi-modal imaging","author":"Dumbryte","year":"2023","journal-title":"Bioengineering"},{"issue":"8","key":"10.1016\/j.matdes.2025.114910_b0025","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1177\/154405910808700802","article-title":"Degradation, fatigue, and failure of resin dental composite materials","volume":"87","author":"Drummond","year":"2008","journal-title":"J. Dent. Res."},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0030","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/jerd.13371","article-title":"Advances in dental restorations: a comprehensive review of machinable and 3D-printed ceramic-reinforced composites","volume":"37","author":"Duarte","year":"2025","journal-title":"J. Esthet. Restor. Dent."},{"key":"10.1016\/j.matdes.2025.114910_b0035","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.matdes.2016.01.046","article-title":"Design and development of self-healing dental composites","volume":"94","author":"Huyang","year":"2016","journal-title":"Mater. Des."},{"issue":"3","key":"10.1016\/j.matdes.2025.114910_b0040","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jdent.2015.01.009","article-title":"Development of novel self-healing and antibacterial dental composite containing calcium phosphate nanoparticles","volume":"43","author":"Wu","year":"2015","journal-title":"J. Dent."},{"issue":"10","key":"10.1016\/j.matdes.2025.114910_b0045","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1016\/j.polymdegradstab.2006.04.026","article-title":"Thermal stability of microencapsulated epoxy resins with poly(urea\u2013formaldehyde)","volume":"91","author":"Yuan","year":"2006","journal-title":"Polym. Degrad. Stab."},{"key":"10.1016\/j.matdes.2025.114910_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2022.111142","article-title":"Fatigue-crack propagation behavior in microcapsule-containing self-healing polymeric networks","volume":"223","author":"Fugolin","year":"2022","journal-title":"Mater. Des."},{"issue":"1\u20133","key":"10.1016\/j.matdes.2025.114910_b0055","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.colsurfa.2010.09.009","article-title":"Preparation and characterization of novel melamine modified poly(urea\u2013formaldehyde) self-repairing microcapsules","volume":"371","author":"Tong","year":"2010","journal-title":"Colloids Surf A Physicochem Eng Asp"},{"key":"10.1016\/j.matdes.2025.114910_b0060","doi-asserted-by":"crossref","DOI":"10.3390\/polym8040125","article-title":"Microcapsules filled with a palm oil-based alkyd as healing agent for epoxy matrix","author":"Shahabudin","year":"2016","journal-title":"Polymers"},{"key":"10.1016\/j.matdes.2025.114910_b0065","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.colsurfb.2015.02.029","article-title":"Development of melamine\u2013formaldehyde resin microcapsules with low formaldehyde emission suited for seed treatment","volume":"128","author":"Yuan","year":"2015","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.matdes.2025.114910_b0070","series-title":"IARC monographs on the evaluation of carcinogenic risks to humans","author":"Organization","year":"2006"},{"key":"10.1016\/j.matdes.2025.114910_b0075","series-title":"Formaldehyde, 2-Butoxyethanol and 1-Tert-Butoxypropan-2-Ol\u2014IARC Monographs on the Evaluation of Carcinogenic risks to Humans","author":"Organization","year":"2006"},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0080","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s41021-021-00183-5","article-title":"Formaldehyde exposure and leukemia risk: a comprehensive review and network-based toxicogenomic approach","volume":"43","author":"Kang","year":"2021","journal-title":"Genes Environ."},{"issue":"17","key":"10.1016\/j.matdes.2025.114910_b0085","doi-asserted-by":"crossref","DOI":"10.3390\/polym16172410","article-title":"Improving self-healing dental-restorative materials with functionalized and reinforced microcapsules","volume":"16","author":"Huynh","year":"2024","journal-title":"Polymers (Basel)"},{"key":"10.1016\/j.matdes.2025.114910_b0090","article-title":"UV-triggered self-healing SiO2\/PDA hybrid microcapsules with both enhanced UV-shielding ability and improved compatibility for epoxy resin coating","volume":"163","author":"Li","year":"2022","journal-title":"Prog. Org. Coat."},{"key":"10.1016\/j.matdes.2025.114910_b0095","article-title":"Preparation of a novel IPDI\/PUF@ CeO2 bi-functional microcapsules and its improvement for the self-healing and anti-corrosion performance in epoxy coatings","volume":"169","author":"Liu","year":"2022","journal-title":"Prog. Org. Coat."},{"issue":"19","key":"10.1016\/j.matdes.2025.114910_b0100","doi-asserted-by":"crossref","first-page":"36544","DOI":"10.1016\/j.ceramint.2024.07.039","article-title":"Effect of ZrO2 nanoparticles on the self-lubrication behavior of the linseed oil-loaded microcapsule\/epoxy composite coatings","volume":"50","author":"Hasan","year":"2024","journal-title":"Ceram. Int."},{"issue":"10","key":"10.1016\/j.matdes.2025.114910_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2025.e43433","article-title":"Study on the self-lubrication and corrosion resistance of the epoxy coatings containing microcapsules with poly urea-formaldehyde\/nanozirconia as nanocomposite shell","volume":"11","author":"Hasan","year":"2025","journal-title":"Heliyon"},{"key":"10.1016\/j.matdes.2025.114910_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2024.106372","article-title":"Effect of silanization of poly (urea-formaldehyde) microcapsules on the flexural strength and self-healing efficiency of an experimental self-healing dental resin composite (an in-vitro study)","volume":"151","author":"Rozza","year":"2024","journal-title":"J. Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.matdes.2025.114910_b0115","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.eurpolymj.2016.07.008","article-title":"Thiolactone-based polymers for formaldehyde scavenging coatings","volume":"82","author":"Resetco","year":"2016","journal-title":"Eur. Polym. J."},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0120","doi-asserted-by":"crossref","DOI":"10.1002\/app.53273","article-title":"Assessment of mechanical and healing behaviors of glass fibers-epoxy composite containing the microcapsules with the nanocomposite shell","volume":"140","author":"Ebrahimnezhad-Khaljiri","year":"2023","journal-title":"J. Appl. Polym. Sci."},{"key":"10.1016\/j.matdes.2025.114910_b0125","doi-asserted-by":"crossref","DOI":"10.1177\/15280837221119833","article-title":"The effect of capsulated nanosilica-epoxy healing agents on the self-healing ability of glass fibers-epoxy composites under mechanical loading","volume":"52","author":"Ebrahimnezhad-Khaljiri","year":"2022","journal-title":"J. Ind. Text."},{"issue":"5","key":"10.1016\/j.matdes.2025.114910_b0130","doi-asserted-by":"crossref","DOI":"10.3390\/jfb15050117","article-title":"Tailoring microemulsification techniques for the encapsulation of diverse cargo: a systematic analysis of poly (urea-formaldehyde) microcapsules","volume":"15","author":"Rajasekaran","year":"2024","journal-title":"J Funct Biomater"},{"issue":"5","key":"10.1016\/j.matdes.2025.114910_b0135","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1016\/j.apsusc.2008.06.170","article-title":"Surface modification of self-healing poly(urea-formaldehyde) microcapsules using silane-coupling agent","volume":"255","author":"Li","year":"2008","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.matdes.2025.114910_b0140","article-title":"Effects of interface bonding on the macro-mechanical properties of microcapsule\/epoxy resin composites","volume":"34","author":"Dou","year":"2022","journal-title":"Surf. Interfaces"},{"key":"10.1016\/j.matdes.2025.114910_b0145","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.cplett.2013.11.043","article-title":"Surface modification of nanosilica with 3-mercaptopropyl trimethoxysilane: experimental and theoretical study on the surface interaction","volume":"591","author":"Wu","year":"2014","journal-title":"Chem. Phys. Lett."},{"key":"10.1016\/j.matdes.2025.114910_b0150","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.apsusc.2014.08.199","article-title":"Controlling the synergetic effects in (3-aminopropyl) trimethoxysilane and (3-mercaptopropyl) trimethoxysilane coadsorption on stainless steel surfaces","volume":"317","author":"Vuori","year":"2014","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.matdes.2025.114910_b0155","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ijadhadh.2015.09.007","article-title":"Studying various mixtures of 3-aminopropyltriethoxysilane (APS) and tetraethylorthosilicate (TEOS) silanes on the corrosion resistance of mild steel and adhesion properties of epoxy coating","volume":"63","author":"Ramezanzadeh","year":"2015","journal-title":"Int. J. Adhes. Adhes."},{"issue":"13","key":"10.1016\/j.matdes.2025.114910_b0160","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1016\/j.jmmm.2009.12.038","article-title":"Producing ultra-thin silica coatings on iron-oxide nanoparticles to improve their surface reactivity","volume":"322","author":"Kralj","year":"2010","journal-title":"J. Magn. Magn. Mater."},{"key":"10.1016\/j.matdes.2025.114910_b0165","doi-asserted-by":"crossref","unstructured":"S.M. Mirabedini, M. Esfandeh, R.R. Farnood, P. Rajabi, Amino-silane surface modification of urea-formaldehyde microcapsules containing linseed oil for improved epoxy matrix compatibility. Part I: optimizing silane treatment conditions, Progress in Organic Coatings 136 (2019).","DOI":"10.1016\/j.porgcoat.2019.105242"},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0170","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1006\/abio.1996.0048","article-title":"A rapid formaldehyde assay using purpald reagent: application under periodation conditions","volume":"234","author":"Quesenberry","year":"1996","journal-title":"Anal. Biochem."},{"issue":"1\u20132","key":"10.1016\/j.matdes.2025.114910_b0175","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.cej.2009.07.018","article-title":"Influence of process parameters on microcapsules loaded with n-hexadecane prepared by in situ polymerization","volume":"155","author":"Sala\u00fcn","year":"2009","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.matdes.2025.114910_b0180","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.colsurfa.2017.02.053","article-title":"Synthesis of epoxy-loaded poly(melamine-formaldehyde) microcapsules: effect of pH regulation method and emulsifier selection","volume":"520","author":"Ollier","year":"2017","journal-title":"Colloids Surf A Physicochem Eng Asp"},{"issue":"9","key":"10.1016\/j.matdes.2025.114910_b0185","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.1007\/s10853-019-04297-8","article-title":"Changes in microcapsules under heating: the effect of particle size on thermal stability and breakability","volume":"55","author":"Zhao","year":"2020","journal-title":"Journal of Materials Science"},{"issue":"7","key":"10.1016\/j.matdes.2025.114910_b0190","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1080\/00218460490477134","article-title":"The effect of composition on surface properties of polyester\u2013melamine thermoset coatings","volume":"80","author":"Lukey","year":"2004","journal-title":"J. Adhes."},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0195","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41368-023-00226-3","article-title":"Micromechanical interlocking structure at the filler\/resin interface for dental composites: a review","volume":"15","author":"Zhang","year":"2023","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.matdes.2025.114910_b0200","article-title":"Effects of interface bonding on the macro-mechanical properties of microcapsule\/epoxy resin composites","volume":"34","author":"Dou","year":"2022","journal-title":"Surf. Interfaces"},{"key":"10.1016\/j.matdes.2025.114910_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.conbuildmat.2022.126622","article-title":"Preparation and performance analysis of dopamine hydrochloride functionalized E-51@ MPF\/SiO2 double-wall microcapsules for microcracks self-healing in cement-based materials","volume":"325","author":"Zhou","year":"2022","journal-title":"Constr. Build. Mater."},{"issue":"20","key":"10.1016\/j.matdes.2025.114910_b0210","doi-asserted-by":"crossref","first-page":"15539","DOI":"10.1039\/C4RA16327C","article-title":"Urea formaldehyde (UF) microcapsules loaded with corrosion inhibitor for enhancing the anti-corrosive properties of acrylic-based multi-functional PU coatings","volume":"5","author":"Marathe","year":"2015","journal-title":"RSC Adv."},{"key":"10.1016\/j.matdes.2025.114910_b0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.compositesb.2021.109138","article-title":"Temperature adaptive microcapsules for self-healing cementitious materials","volume":"223","author":"Ren","year":"2021","journal-title":"Compos. B Eng."},{"issue":"12","key":"10.1016\/j.matdes.2025.114910_b0220","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.3390\/ma9121025","article-title":"Micromechanical properties of a new polymeric microcapsule for self-healing cementitious materials","volume":"9","author":"Lv","year":"2016","journal-title":"Materials"},{"issue":"6\u20137","key":"10.1016\/j.matdes.2025.114910_b0225","first-page":"389","article-title":"Synthesis and characterization of melamine\u2010urea\u2010formaldehyde microcapsules containing ENB\u2010based self\u2010healing agents","volume":"294","author":"Liu","year":"2009","journal-title":"Macromol. Mater. Eng."},{"key":"10.1016\/j.matdes.2025.114910_b0230","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.enconman.2014.01.042","article-title":"Microencapsulation of a fatty acid with Poly(melamine\u2013urea\u2013formaldehyde)","volume":"80","author":"Konuklu","year":"2014","journal-title":"Energ. Conver. Manage."},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0235","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1021\/acs.langmuir.3c02463","article-title":"Droplet size distribution in emulsions","volume":"40","author":"L\u2019Estim\u00e9","year":"2024","journal-title":"Langmuir"},{"key":"10.1016\/j.matdes.2025.114910_b0240","doi-asserted-by":"crossref","DOI":"10.3390\/polym12123064","article-title":"Effect of microcapsule content on diels-alder room temperature self-healing thermosets","author":"Santos","year":"2020","journal-title":"Polymers"},{"issue":"15","key":"10.1016\/j.matdes.2025.114910_b0245","doi-asserted-by":"crossref","first-page":"4409","DOI":"10.1007\/s00216-022-03906-x","article-title":"Surface chemistry of metal oxide nanoparticles: NMR and TGA quantification","volume":"414","author":"Kunc","year":"2022","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.matdes.2025.114910_b0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.apsusc.2019.144978","article-title":"Investigation on particle properties and extent of functionalization of silica nanoparticles","volume":"506","author":"Idris","year":"2020","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.matdes.2025.114910_b0255","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.apsusc.2016.10.102","article-title":"Surface modification of silicon carbide with silane coupling agent and hexadecyl iodiele","volume":"394","author":"Shang","year":"2017","journal-title":"Appl. Surf. Sci."},{"issue":"3","key":"10.1016\/j.matdes.2025.114910_b0260","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1007\/s00289-018-2425-8","article-title":"Morphological study of surface-modified urea\u2013formaldehyde microcapsules using 3-aminopropyltriethoxy silane","volume":"76","author":"Katoueizadeh","year":"2018","journal-title":"Polym. Bull."},{"key":"10.1016\/j.matdes.2025.114910_b0265","article-title":"Improving thermal stability of polyurethane through the addition of hyperbranched polysiloxane","author":"Liu","year":"2019","journal-title":"Polymers"},{"key":"10.1016\/j.matdes.2025.114910_b0270","doi-asserted-by":"crossref","DOI":"10.3390\/polym11030537","article-title":"Kinetics of alkoxysilanes and organoalkoxysilanes polymerization: a review","author":"Issa","year":"2019","journal-title":"Polymers"},{"issue":"2\u20133","key":"10.1016\/j.matdes.2025.114910_b0275","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0022-3093(02)01637-X","article-title":"Infrared spectroscopy of sol\u2013gel derived silica-based films: a spectra-microstructure overview","volume":"316","author":"Innocenzi","year":"2003","journal-title":"J. Non Cryst. Solids"},{"issue":"23","key":"10.1016\/j.matdes.2025.114910_b0280","doi-asserted-by":"crossref","first-page":"6057","DOI":"10.1039\/D4MH00796D","article-title":"Double emulsion microencapsulation of ionic liquids for carbon capture","volume":"11","author":"Starvaggi","year":"2024","journal-title":"Mater. Horiz."},{"issue":"9","key":"10.1016\/j.matdes.2025.114910_b0285","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1016\/j.apsusc.2009.11.020","article-title":"Thermal stability of thiol and silane monolayers: a comparative study","volume":"256","author":"Chandekar","year":"2010","journal-title":"Appl. Surf. Sci."},{"issue":"3","key":"10.1016\/j.matdes.2025.114910_b0290","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0169-4332(01)00399-3","article-title":"Structure and morphology of self-assembled 3-mercaptopropyltrimethoxysilane layers on silicon oxide","volume":"181","author":"Hu","year":"2001","journal-title":"Appl. Surf. Sci."},{"issue":"9","key":"10.1016\/j.matdes.2025.114910_b0295","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1039\/D3PY01367G","article-title":"A tutorial review of linear rheology for polymer chemists: basics and best practices for covalent adaptable networks","volume":"15","author":"Ricarte","year":"2024","journal-title":"Polym. Chem."},{"issue":"8","key":"10.1016\/j.matdes.2025.114910_b0300","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1163\/156856106777638671","article-title":"Thermal analysis study of viscoelastic properties and activation energy of melamine-modified urea-formaldehyde resins","volume":"20","author":"Kim","year":"2006","journal-title":"J. Adhes. Sci. Technol."},{"issue":"5","key":"10.1016\/j.matdes.2025.114910_b0305","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1007\/s00396-018-4316-9","article-title":"Rheological and thermal properties of suspensions of microcapsules containing phase change materials","volume":"296","author":"Cao","year":"2018","journal-title":"Colloid Polym. Sci."},{"issue":"39","key":"10.1016\/j.matdes.2025.114910_b0310","doi-asserted-by":"crossref","first-page":"25702","DOI":"10.1021\/acsomega.1c03896","article-title":"Thermal degradation kinetics of urea-formaldehyde resins modified by almond shells","volume":"6","author":"Chen","year":"2021","journal-title":"ACS Omega"},{"issue":"3","key":"10.1016\/j.matdes.2025.114910_b0315","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1002\/app.35282","article-title":"Production of melamine fortified urea\u2010formaldehyde resins with low formaldehyde emission","volume":"124","author":"Paiva","year":"2011","journal-title":"J. Appl. Polym. Sci."},{"key":"10.1016\/j.matdes.2025.114910_b0320","unstructured":"<BioRes_10_2_3265_Luo_Effect_Melamine_Allocation_Proportion_Chemical_6840.pdf>."},{"key":"10.1016\/j.matdes.2025.114910_b0325","doi-asserted-by":"crossref","unstructured":"M. Leskov\u0161ek, J. Kortnik, U. Stankovi\u010d Elesini, B. \u0160umiga, Characterisation of melamine formaldehyde microspheres synthesised with prolonged microencapsulated reaction time, 42(4) (2022) 288-297.","DOI":"10.1515\/polyeng-2021-0289"},{"issue":"3","key":"10.1016\/j.matdes.2025.114910_b0330","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1002\/jbm.a.31448","article-title":"Hydrogen bonding interactions in methacrylate monomers and polymers","volume":"83","author":"Lemon","year":"2007","journal-title":"J. Biomed. Mater. Res. A"},{"issue":"7","key":"10.1016\/j.matdes.2025.114910_b0335","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.tcb.2019.03.006","article-title":"The epigenetics of stem cell aging comes of age","volume":"29","author":"Chen","year":"2019","journal-title":"Trends Cell Biol."},{"issue":"4","key":"10.1016\/j.matdes.2025.114910_b0340","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/cre2.297","article-title":"Differential expression of drug resistance genes in CD146 positive dental pulp derived stem cells and CD146 negative fibroblasts","volume":"6","author":"Tavangar","year":"2020","journal-title":"Clin. Exp. Dent. Res."},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0345","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s13287-018-0831-3","article-title":"Dental pulp stem cells used to deliver the anticancer drug paclitaxel","volume":"9","author":"Salehi","year":"2018","journal-title":"Stem Cell Res. Ther."},{"issue":"11","key":"10.1016\/j.matdes.2025.114910_b0350","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.5966\/sctm.2015-0095","article-title":"Concise review: stem cell microenvironment on a chip: current technologies for tissue engineering and stem cell biology","volume":"4","author":"Park","year":"2015","journal-title":"Stem Cells Transl. Med."},{"key":"10.1016\/j.matdes.2025.114910_b0355","unstructured":"Biological evaluation of medical devices?Part 5: Tests for in vitro cytotoxicity, ANSI\/AAMI\/ISO 10993-5:2009\/(R)2022; Biological evaluation of medical devices?Part 5: Tests for in vitro cytotoxicity2022."},{"issue":"5","key":"10.1016\/j.matdes.2025.114910_b0360","doi-asserted-by":"crossref","first-page":"5789","DOI":"10.3390\/ijms13055789","article-title":"Relationships between base-catalyzed hydrolysis rates or glutathione reactivity for acrylates and methacrylates and their NMR spectra or heat of formation","volume":"13","author":"Fujisawa","year":"2012","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.matdes.2025.114910_b0365","doi-asserted-by":"crossref","DOI":"10.3390\/toxics12120924","article-title":"The perils of methanol exposure: insights into toxicity and clinical management","author":"Alrashed","year":"2024","journal-title":"Toxics"},{"key":"10.1016\/j.matdes.2025.114910_b0370","series-title":"Biology and engineering of stem cell niches","first-page":"195","article-title":"Matrix chemistry controlling stem cell behavior","author":"Klecker","year":"2017"},{"issue":"12","key":"10.1016\/j.matdes.2025.114910_b0375","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0226363","article-title":"Free thiol groups on poly(aspartamide) based hydrogels facilitate tooth-derived progenitor cell proliferation and differentiation","volume":"14","author":"Heged\u0171s","year":"2019","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.matdes.2025.114910_b0380","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1007\/s10570-015-0651-x","article-title":"Modification of bacterial cellulose with organosilanes to improve attachment and spreading of human fibroblasts","volume":"22","author":"Taokaew","year":"2015","journal-title":"Cellulose (lond)"},{"issue":"11","key":"10.1016\/j.matdes.2025.114910_b0385","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.tcb.2012.08.002","article-title":"Redox control of cell proliferation","volume":"22","author":"Chiu","year":"2012","journal-title":"Trends Cell Biol."},{"issue":"4","key":"10.1016\/j.matdes.2025.114910_b0390","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1166\/jnn.2011.3803","article-title":"Cytotoxicity tests of water soluble ZnS and CdS quantum dots","volume":"11","author":"Li","year":"2011","journal-title":"J. Nanosci. Nanotechnol."},{"issue":"7","key":"10.1016\/j.matdes.2025.114910_b0395","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"issue":"18","key":"10.1016\/j.matdes.2025.114910_b0400","doi-asserted-by":"crossref","DOI":"10.3390\/ijms221810167","article-title":"The osteogenic differentiation of human dental pulp stem cells through G0\/G1 arrest and the p-ERK\/Runx-2 pathway by sonic vibration","volume":"22","author":"Lee","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.matdes.2025.114910_b0405","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1080\/01926230701320337","article-title":"Apoptosis: a review of programmed cell death","volume":"35","author":"Elmore","year":"2007","journal-title":"Toxicol. Pathol."},{"issue":"6","key":"10.1016\/j.matdes.2025.114910_b0410","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.dental.2011.03.002","article-title":"Effects of HEMA and TEDGMA on the in vitro odontogenic differentiation potential of human pulp stem\/progenitor cells derived from deciduous teeth","volume":"27","author":"Bakopoulou","year":"2011","journal-title":"Dent. Mater."},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0415","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00784-010-0508-5","article-title":"Oxidative stress and cytotoxicity generated by dental composites in human pulp cells","volume":"16","author":"Krifka","year":"2012","journal-title":"Clin. Oral Invest."},{"issue":"2","key":"10.1016\/j.matdes.2025.114910_b0420","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3390\/jfb13020056","article-title":"Cytotoxicity of methacrylate dental resins to human gingival fibroblasts","volume":"13","author":"Sulek","year":"2022","journal-title":"J. Funct. Biomater."},{"issue":"1","key":"10.1016\/j.matdes.2025.114910_b0425","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0147858","article-title":"N-acetyl cysteine depletes reactive oxygen species and prevents dental monomer-induced intrinsic mitochondrial apoptosis in vitro in human dental pulp cells","volume":"11","author":"Jiao","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.matdes.2025.114910_b0430","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1007\/s11033-011-0895-y","article-title":"2-hydroxylethyl methacrylate (HEMA), a tooth restoration component, exerts its genotoxic effects in human gingival fibroblasts trough methacrylic acid, an immediate product of its degradation","volume":"39","author":"Szczepanska","year":"2012","journal-title":"Mol. Biol. Rep."}],"container-title":["Materials &amp; Design"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264127525013309?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0264127525013309?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T19:21:55Z","timestamp":1773861715000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0264127525013309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":86,"alternative-id":["S0264127525013309"],"URL":"https:\/\/doi.org\/10.1016\/j.matdes.2025.114910","relation":{},"ISSN":["0264-1275"],"issn-type":[{"value":"0264-1275","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessment of physicochemical properties and biological responses of chemically surface-modified microcapsules for self-healing dental restorative materials","name":"articletitle","label":"Article Title"},{"value":"Materials & Design","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.matdes.2025.114910","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"114910"}}