{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T22:26:44Z","timestamp":1787178404638,"version":"build-2736575974"},"reference-count":57,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["manualtherapyjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Manual Therapy"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.math.2014.10.003","type":"journal-article","created":{"date-parts":[[2014,10,14]],"date-time":"2014-10-14T08:37:19Z","timestamp":1413275839000},"page":"335-341","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Adverse events among seniors receiving spinal manipulation and exercise in a randomized clinical trial"],"prefix":"10.1016","volume":"20","author":[{"given":"Michele","family":"Maiers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roni","family":"Evans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Hartvigsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Schulz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert","family":"Bronfort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl.\u00a01","key":"10.1016\/j.math.2014.10.003_bib1","first-page":"i1","article-title":"Guidance on the management of pain in older people","volume":"42","author":"Abdulla","year":"2013","journal-title":"Age Ageing"},{"key":"10.1016\/j.math.2014.10.003_bib2","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/1471-2474-12-172","article-title":"Management of pain induced by exercise and mobilization during physical therapy programs: views of patients and care providers","volume":"12","author":"Alami","year":"2011","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.math.2014.10.003_bib3","unstructured":"American College of Sports Medicine. ACSM Current Comment \u2013 Exercise and the Older Adult. Indianapolis, IN, http:\/\/www.acsm.org\/docs\/current-comments\/exerciseandtheolderadult.pdf?sfvrsn=4. Accessed 09.09.14"},{"issue":"6","key":"10.1016\/j.math.2014.10.003_bib4","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1046\/j.1532-5415.2001.00496.x","article-title":"Exercise prescription for older adults with osteoarthritis pain: consensus practice recommendations","volume":"49","author":"American Geriatrics Society Panel on Exercise and Osteoarthritis","year":"2001","journal-title":"JAGS"},{"issue":"7","key":"10.1016\/j.math.2014.10.003_bib5","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1161\/01.STR.0000077015.90334.A7","article-title":"Triggers of subarachnoid hemorrhage: role of physical exertion, smoking, and alcohol in the Australasian Cooperative Research on Subarachnoid Hemorrhage Study (ACROSS)","volume":"34","author":"Anderson","year":"2003","journal-title":"Stroke"},{"issue":"10","key":"10.1016\/j.math.2014.10.003_bib6","doi-asserted-by":"crossref","first-page":"3155","DOI":"10.1161\/STR.0000000000000016","article-title":"Cervical arterial dissections and association with cervical manipulative therapy: a statement for healthcare professionals from the American heart association\/American stroke association","volume":"45","author":"Biller","year":"2014","journal-title":"Stroke"},{"issue":"4","key":"10.1016\/j.math.2014.10.003_bib7","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1310\/tsr2004-317","article-title":"High-intensity interval training in stroke rehabilitation","volume":"20","author":"Boyne","year":"2013","journal-title":"Top Stroke Rehabil"},{"issue":"1 Pt 1","key":"10.1016\/j.math.2014.10.003_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/0003-4819-156-1-201201030-00002","article-title":"Spinal manipulation, medication, or home exercise with advice for acute and subacute neck pain: a randomized trial","volume":"156","author":"Bronfort","year":"2012","journal-title":"Ann Intern Med"},{"issue":"3","key":"10.1016\/j.math.2014.10.003_bib9","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.math.2004.03.001","article-title":"How common are side effects of spinal manipulation and can these side effects be predicted?","volume":"9","author":"Cagnie","year":"2004","journal-title":"Man Ther"},{"issue":"5","key":"10.1016\/j.math.2014.10.003_bib10","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.math.2011.02.001","article-title":"Defining adverse events in manual therapy: an exploratory qualitative analysis of the patient perspective","volume":"16","author":"Carlesso","year":"2011","journal-title":"Man Ther"},{"issue":"4S","key":"10.1016\/j.math.2014.10.003_bib11","doi-asserted-by":"crossref","first-page":"S176","DOI":"10.1097\/BRS.0b013e3181644600","article-title":"Risk of vertebrobasilar stroke and chiropractic care: results of a population-based case-control and case-crossover study","volume":"33","author":"Cassidy","year":"2008","journal-title":"Spine"},{"key":"10.1016\/j.math.2014.10.003_bib12","series-title":"How much physical activity do older adults need?","author":"Centers for Disease Control and Prevention","year":"2014"},{"issue":"1","key":"10.1016\/j.math.2014.10.003_bib13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/2045-709X-20-3","article-title":"The role of chiropractic care in older adults","volume":"20","author":"Dougherty","year":"2012","journal-title":"Chiropr Man Therap"},{"key":"10.1016\/j.math.2014.10.003_bib14","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/1471-2474-12-219","article-title":"Symptomatic reactions, clinical outcomes and patient satisfaction associated with upper cervical chiropractic care: a prospective, multicenter, cohort study","volume":"12","author":"Eriksen","year":"2011","journal-title":"BMC Musculoskelet Disord"},{"issue":"3","key":"10.1016\/j.math.2014.10.003_bib15","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1161\/01.STR.32.3.809","article-title":"Life-threatening complications of spinal manipulation","volume":"32","author":"Ernst","year":"2001","journal-title":"Stroke"},{"issue":"8","key":"10.1016\/j.math.2014.10.003_bib16","doi-asserted-by":"crossref","first-page":"376","DOI":"10.5694\/j.1326-5377.2002.tb04459.x","article-title":"Manipulation of the cervical spine: a systematic review of case reports of serious adverse events, 1995\u20132001","volume":"176","author":"Ernst","year":"2002","journal-title":"Med J Aust"},{"issue":"11","key":"10.1016\/j.math.2014.10.003_bib17","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1097\/BRS.0b013e31823b3bdf","article-title":"Supervised exercise with and without spinal manipulation perform similarly and better than home exercise for chronic neck pain: a randomized controlled trial","volume":"37","author":"Evans","year":"2012","journal-title":"Spine"},{"issue":"6","key":"10.1016\/j.math.2014.10.003_bib18","doi-asserted-by":"crossref","first-page":"471","DOI":"10.2165\/11536530-000000000-00000","article-title":"Management of chronic arthritis pain in the elderly","volume":"27","author":"Fitzcharles","year":"2010","journal-title":"Drugs Aging"},{"issue":"3","key":"10.1016\/j.math.2014.10.003_bib19","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J\u00a0Psychiatr Res"},{"key":"10.1016\/j.math.2014.10.003_bib20","first-page":"CD004249","article-title":"Manipulation or mobilisation for neck pain","volume":"1","author":"Gross","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.math.2014.10.003_bib21","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/00003086-198310000-00010","article-title":"Spinal manipulative therapy. A status report","volume":"179","author":"Haldeman","year":"1983","journal-title":"Clin Orthop Relat Res"},{"issue":"7","key":"10.1016\/j.math.2014.10.003_bib22","first-page":"905","article-title":"Arterial dissections following cervical manipulation: the chiropractic experience","volume":"165","author":"Haldeman","year":"2001","journal-title":"CMAJ"},{"issue":"5","key":"10.1016\/j.math.2014.10.003_bib23","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/s00586-003-0542-y","article-title":"Back pain remains a common symptom in old age. A population-based study of 4486 Danish twins aged 70\u2013102","volume":"12","author":"Hartvigsen","year":"2003","journal-title":"Eur Spine J"},{"issue":"5","key":"10.1016\/j.math.2014.10.003_bib24","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1097\/01.BRS.0000099394.18994.2F","article-title":"Back and neck pain exhibit many common features in old age. A population based study of 4,486 Danish twins aged 70\u2013102","volume":"29","author":"Hartvigsen","year":"2004","journal-title":"Spine"},{"issue":"10","key":"10.1016\/j.math.2014.10.003_bib25","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1111\/j.1742-1241.2012.03004.x","article-title":"Assessing the risk of stroke from neck manipulation: a systematic review","volume":"66","author":"Haynes","year":"2012","journal-title":"Int J Clin Pract"},{"issue":"2","key":"10.1016\/j.math.2014.10.003_bib26","doi-asserted-by":"crossref","first-page":"e42","DOI":"10.1371\/journal.pmed.0020042","article-title":"Communicating with patients about harms and risks","volume":"2","author":"Herxheimer","year":"2005","journal-title":"PLoS Med"},{"issue":"4 Suppl.","key":"10.1016\/j.math.2014.10.003_bib27","doi-asserted-by":"crossref","first-page":"S123","DOI":"10.1097\/BRS.0b013e3181644b1d","article-title":"Treatment of neck pain: noninvasive interventions: results of the bone and joint decade 2000\u20132010 task force on neck pain and its associated disorders","volume":"33","author":"Hurwitz","year":"2008","journal-title":"Spine"},{"issue":"1","key":"10.1016\/j.math.2014.10.003_bib28","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jmpt.2003.11.002","article-title":"Adverse reactions to chiropractic treatment and their effects on satisfaction and clinical outcomes among patients enrolled in the UCLA neck pain study","volume":"27","author":"Hurwitz","year":"2004","journal-title":"J\u00a0Manip Physiol Ther"},{"issue":"3","key":"10.1016\/j.math.2014.10.003_bib29","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.math.2012.09.009","article-title":"Diagnostic accuracy of premanipulative vertebrobasilar insufficiency tests: a systematic review","volume":"18","author":"Hutting","year":"2013","journal-title":"Man Ther"},{"issue":"10","key":"10.1016\/j.math.2014.10.003_bib30","doi-asserted-by":"crossref","first-page":"781","DOI":"10.7326\/0003-4819-141-10-200411160-00009","article-title":"Better reporting of harms in randomized trials: an extension of the CONSORT statement","volume":"141","author":"Ioannidis","year":"2004","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.1016\/j.math.2014.10.003_bib31","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2165\/00002018-200225020-00002","article-title":"Improving safety reporting from randomised trials","volume":"25","author":"Ioannidis","year":"2002","journal-title":"Drug Saf"},{"key":"10.1016\/j.math.2014.10.003_bib32","first-page":"CD004250","article-title":"Exercises for mechanical neck disorders","volume":"8","author":"Kay","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"issue":"11","key":"10.1016\/j.math.2014.10.003_bib33","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1212\/01.WNL.0000145842.25520.A2","article-title":"Triggering risk factors for ischemic stroke: a case-crossover study","volume":"63","author":"Koton","year":"2004","journal-title":"Neurology"},{"issue":"2\u20133","key":"10.1016\/j.math.2014.10.003_bib34","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1159\/000105683","article-title":"Level of physical activity in the week preceding an ischemic stroke","volume":"24","author":"Krarup","year":"2007","journal-title":"Cerebrovasc Dis"},{"issue":"9","key":"10.1016\/j.math.2014.10.003_bib35","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.apmr.2010.06.001","article-title":"Adverse events reported in progressive resistance strength training trials in older adults: 2 sides of a coin","volume":"91","author":"Liu","year":"2010","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1016\/j.math.2014.10.003_bib36","article-title":"Spinal manipulative therapy and exercise for seniors with chronic neck pain","author":"Maiers","year":"2013","journal-title":"Spine J"},{"issue":"1","key":"10.1016\/j.math.2014.10.003_bib37","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/1471-2474-8-94","article-title":"Chiropractic and exercise for seniors with low back pain or neck pain: the design of two randomized clinical trials","volume":"8","author":"Maiers","year":"2007","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.math.2014.10.003_bib38","series-title":"Qualitative data analysis: an expanded sourcebook","author":"Miles","year":"1994"},{"issue":"4","key":"10.1016\/j.math.2014.10.003_bib39","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.math.2010.02.007","article-title":"Manual therapy and exercise for neck pain: a systematic review","volume":"15","author":"Miller","year":"2010","journal-title":"Man Ther"},{"issue":"1","key":"10.1016\/j.math.2014.10.003_bib40","doi-asserted-by":"crossref","first-page":"R20","DOI":"10.1186\/ar2373","article-title":"What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs","volume":"10","author":"Moore","year":"2008","journal-title":"Arthritis Res Ther"},{"issue":"3","key":"10.1016\/j.math.2014.10.003_bib41","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1093\/aje\/kwq369","article-title":"Physical activity and onset of acute ischemic stroke: the stroke onset study","volume":"173","author":"Mostofsky","year":"2011","journal-title":"Am J Epidemiol"},{"issue":"597","key":"10.1016\/j.math.2014.10.003_bib42","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3399\/bjgp12X636236","article-title":"Communicating risk to patients and the public","volume":"62","author":"Naik","year":"2012","journal-title":"Br J Gen Pract"},{"issue":"1","key":"10.1016\/j.math.2014.10.003_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.rdc.2012.10.004","article-title":"Epidemiology of osteoarthritis","volume":"39","author":"Neogi","year":"2013","journal-title":"Rheum Dis Clin North Am"},{"issue":"5","key":"10.1016\/j.math.2014.10.003_bib44","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1503\/cmaj.050873","article-title":"Comparison of evidence on harms of medical interventions in randomized and nonrandomized studies","volume":"174","author":"Papanikolaou","year":"2006","journal-title":"CMAJ"},{"key":"10.1016\/j.math.2014.10.003_bib45","series-title":"Chiropractic technique: principles and procedures","author":"Peterson","year":"2011"},{"issue":"19","key":"10.1016\/j.math.2014.10.003_bib46","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1001\/archinternmed.2009.306","article-title":"Reporting of safety results in published reports of randomized controlled trials","volume":"169","author":"Pitrou","year":"2009","journal-title":"Arch Intern Med"},{"issue":"25","key":"10.1016\/j.math.2014.10.003_bib47","doi-asserted-by":"crossref","first-page":"E950","DOI":"10.1097\/BRS.0b013e3181891737","article-title":"Benign adverse events following chiropractic care for neck pain are associated with worse short-term outcomes but not worse outcomes at three months","volume":"33","author":"Rubinstein","year":"2008","journal-title":"Spine"},{"issue":"3","key":"10.1016\/j.math.2014.10.003_bib48","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.math.2013.11.005","article-title":"International framework for examination of the cervical region for potential of cervical arterial dysfunction prior to orthopaedic manual therapy intervention","volume":"19","author":"Rushton","year":"2014","journal-title":"Man Ther"},{"key":"10.1016\/j.math.2014.10.003_bib49","author":"Scholten-Peeters","year":"2014","journal-title":"Man Ther"},{"issue":"19","key":"10.1016\/j.math.2014.10.003_bib50","doi-asserted-by":"crossref","first-page":"E413","DOI":"10.1097\/01.brs.0000141178.98157.8e","article-title":"Reliability of spinal palpation for diagnosis of back and neck pain: a systematic review of the literature","volume":"29","author":"Seffinger","year":"2004","journal-title":"Spine"},{"issue":"21","key":"10.1016\/j.math.2014.10.003_bib51","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1097\/BRS.0b013e3181557bb1","article-title":"Safety of chiropractic manipulation of the cervical spine: a prospective national survey","volume":"32","author":"Thiel","year":"2007","journal-title":"Spine"},{"key":"10.1016\/j.math.2014.10.003_bib52","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1472-6882-11-67","article-title":"An evaluation of the completeness of safety reporting in reports of complementary and alternative medicine trials","volume":"11","author":"Turner","year":"2011","journal-title":"BMC Complement Altern Med"},{"key":"10.1016\/j.math.2014.10.003_bib53","series-title":"A\u00a0public health action plan to prevent heart disease and stroke","author":"US Department of Health and Human Services","year":"2003"},{"issue":"5365","key":"10.1016\/j.math.2014.10.003_bib54","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1126\/science.280.5365.855","article-title":"Biodemographic trajectories of longevity","volume":"280","author":"Vaupel","year":"1998","journal-title":"Science"},{"issue":"20","key":"10.1016\/j.math.2014.10.003_bib55","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1097\/BRS.0b013e31829fefe4","article-title":"Outcomes of usual chiropractic. The OUCH randomized controlled trial of adverse events","volume":"38","author":"Walker","year":"2013","journal-title":"Spine"},{"key":"10.1016\/j.math.2014.10.003_bib56","doi-asserted-by":"crossref","first-page":"e3679","DOI":"10.1136\/bmj.e3679","article-title":"Should we abandon cervical spine manipulation for mechanical neck pain? Yes","volume":"344","author":"Wand","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.math.2014.10.003_bib57","series-title":"American Public Health Association: 141st Annual Meeting and Expo; Boston, MA","article-title":"Likelihood of vertebrobasilar stroke following chiropractic spinal manipulation in US adults ages 65\u201399 with neck pain","author":"Whedon","year":"2013"}],"container-title":["Manual Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1356689X14001854?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1356689X14001854?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T19:51:58Z","timestamp":1598385118000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1356689X14001854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":57,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S1356689X14001854"],"URL":"https:\/\/doi.org\/10.1016\/j.math.2014.10.003","relation":{},"ISSN":["1356-689X"],"issn-type":[{"value":"1356-689X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adverse events among seniors receiving spinal manipulation and exercise in a randomized clinical trial","name":"articletitle","label":"Article Title"},{"value":"Manual Therapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.math.2014.10.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}