{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T07:40:50Z","timestamp":1775634050356,"version":"3.50.1"},"reference-count":45,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1016\/j.maturitas.2004.07.013","type":"journal-article","created":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T13:53:41Z","timestamp":1097675621000},"page":"246-253","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["The effect of calcitonin on biochemical markers and zinc excretion in postmenopausal osteoporosis"],"prefix":"10.1016","volume":"51","author":[{"given":"Leyla","family":"Colpan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Gur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remzi","family":"Cevik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kemal","family":"Nas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysegul Jale","family":"Sarac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.maturitas.2004.07.013_bib1","first-page":"358","article-title":"Osteoporosis and the role of diet","volume":"51","author":"Eaton-Evans","year":"1994","journal-title":"Br J Biomed Sci"},{"key":"10.1016\/j.maturitas.2004.07.013_bib2","first-page":"23","article-title":"Low serum copper, a risk factor additional to low dietary calcium in postmenopausal bone loss","volume":"5","author":"Howard","year":"1992","journal-title":"J Trace Elem Exp Med"},{"key":"10.1016\/j.maturitas.2004.07.013_bib3","first-page":"995","article-title":"Role of copper in connective tissue metabolism","volume":"30","author":"Carnes","year":"1971","journal-title":"Fed Proc"},{"key":"10.1016\/j.maturitas.2004.07.013_bib4","series-title":"Clinical chemistry: theory, analysis, and correlation","first-page":"528","article-title":"Bone disease","author":"Itan\u0131","year":"1996"},{"key":"10.1016\/j.maturitas.2004.07.013_bib5","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/00003086-197409000-00084","article-title":"The role of zinc in bone metabolism","volume":"103","author":"Calhoun","year":"1974","journal-title":"Orthopedics"},{"key":"10.1016\/j.maturitas.2004.07.013_bib6","first-page":"1001","article-title":"Connective tissue alterations in zinc deficiency","volume":"30","author":"Westmoreland","year":"1971","journal-title":"Fed Proc"},{"issue":"6","key":"10.1016\/j.maturitas.2004.07.013_bib7","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1248\/bpb.17.862","article-title":"Histomorphological confirmation of the preventive effect of beta-alanyl-l-histidinato zinc on bone loss in ovariectomized rats","volume":"17","author":"Kishi","year":"1994","journal-title":"Biol Pharm Bull"},{"issue":"2","key":"10.1016\/j.maturitas.2004.07.013_bib8","first-page":"203","article-title":"Prolonged administration of beta-alanyl-l-histidinato zinc prevents bone loss in on the deterioration ovariectomized rats","volume":"63","author":"Yamaguchi","year":"1993","journal-title":"Jpn J Biopharmacol"},{"issue":"5","key":"10.1016\/j.maturitas.2004.07.013_bib9","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1248\/bpb.16.486","article-title":"Preventive effect of beta-alanyl-l-histidinato zinc on the deterioration of bone metabolism in ovariectomized rats","volume":"16","author":"Segawa","year":"1993","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.maturitas.2004.07.013_bib10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s774-002-8445-y","article-title":"The role of trace minerals in the pathogenesis of postmenopausal osteoporosis and a new effect of calcitonin","volume":"20","author":"Gur","year":"2002","journal-title":"J Bone Miner Metab"},{"issue":"8","key":"10.1016\/j.maturitas.2004.07.013_bib11","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0009-9120(97)00113-6","article-title":"Biochemical markers of bone metabolism: an overview","volume":"30","author":"Christenson","year":"1997","journal-title":"Clin Biochem"},{"key":"10.1016\/j.maturitas.2004.07.013_bib12","doi-asserted-by":"crossref","unstructured":"Consensus Development Statement. Who are candidates for prevention and treatment for osteoporosis? Osteoporos Int 1997;7:1\u20136.","DOI":"10.1007\/BF01623453"},{"key":"10.1016\/j.maturitas.2004.07.013_bib13","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/jbmr.5650110602","article-title":"Noninvasive assessment of bone mineral and structure: state of the art","volume":"11","author":"Genant","year":"1996","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.maturitas.2004.07.013_bib14","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/S8756-3282(00)00272-6","article-title":"Early response in biochemical markers predicts long-term response in bone mass during HRT in early postmenopausal women","volume":"26","author":"Bjarnason","year":"2000","journal-title":"Bone"},{"key":"10.1016\/j.maturitas.2004.07.013_bib15","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S8756-3282(98)00183-5","article-title":"Biochemical markers can predict the response in bone mass during alendronate treatment in early postmenopausal women","volume":"24","author":"Ravn","year":"1999","journal-title":"Bone"},{"key":"10.1016\/j.maturitas.2004.07.013_bib16","first-page":"2363","article-title":"Monitoring of alendronate treatment and prediction of effect on bone mass by biochemical markers in the early postmenopausal intervention cohort study","volume":"84","author":"Ravn","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.maturitas.2004.07.013_bib17","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S8756-3282(00)00271-4","article-title":"Monitoring individual response to hormone replacement therapy with bone markers","volume":"26","author":"Delmas","year":"2000","journal-title":"Bone"},{"key":"10.1016\/j.maturitas.2004.07.013_bib18","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF01623829","article-title":"Evaluation of bone turnover in type I osteoporosis using biochemical markers specific for both bone formation and bone resorption","volume":"3","author":"Eastell","year":"1993","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.maturitas.2004.07.013_bib19","first-page":"1693","article-title":"Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment","volume":"79","author":"Garnero","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.maturitas.2004.07.013_bib20","first-page":"366","article-title":"The short term effects of conjugated estrogen on bone turnover in older women","volume":"79","author":"Prestwood","year":"1994","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.maturitas.2004.07.013_bib21","first-page":"37","article-title":"Comparison of the effects of estrogen alone and estrogen plus androgen on biochemical markers of bone formation and resorption in postmenopausal women","volume":"81","author":"Raisz","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.maturitas.2004.07.013_bib22","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0009-8981(98)00172-7","article-title":"Urinary bone resorption markers in monitoring treatment of symptomatic osteoporosis","volume":"279","author":"Parvainen","year":"1999","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.maturitas.2004.07.013_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0002-9343(90)90089-V","article-title":"Discontinuous calcitonin treatment of established osteoporosis\u2014effects of withdrawal of treatment","volume":"89","author":"Overgaard","year":"1990","journal-title":"Am J Med"},{"key":"10.1016\/j.maturitas.2004.07.013_bib24","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1002\/jbmr.5650050308","article-title":"Zinc excretion in osteoporotic women","volume":"5","author":"Herzbeg","year":"1990","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.maturitas.2004.07.013_bib25","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S0924-2244(99)00052-7","article-title":"Functional food ingredients for reducing the risks of osteoporosis","volume":"11","author":"Brouns","year":"2000","journal-title":"Trends Food Sci Technol"},{"key":"10.1016\/j.maturitas.2004.07.013_bib26","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/ageing\/24.4.303","article-title":"Zinc biochemical markers of nutrition, and type 1 osteoporosis","volume":"24","author":"Relea","year":"1995","journal-title":"Age Ageing"},{"key":"10.1016\/j.maturitas.2004.07.013_bib27","first-page":"129","article-title":"Blood zinc findings in osteoporosis","volume":"126","author":"Steidl","year":"1990","journal-title":"Acta Univ Palacki Olomuc Fac Med"},{"key":"10.1016\/j.maturitas.2004.07.013_bib28","first-page":"281","article-title":"Relation of magnesium to osteoporosis and calcium urolithiasis","volume":"10","author":"Wallach","year":"1991","journal-title":"Magnes Trace Elem"},{"issue":"1\u20132","key":"10.1016\/j.maturitas.2004.07.013_bib29","first-page":"85","article-title":"Recent data on magnesium and osteoporosis","volume":"1","author":"Cohen","year":"1988","journal-title":"Magnes Res"},{"issue":"2","key":"10.1016\/j.maturitas.2004.07.013_bib30","first-page":"51","article-title":"Biochemical findings in osteoporosis I: the significance of magnesium","volume":"129","author":"Steidl","year":"1990","journal-title":"Cas-Leck-Cesk"},{"issue":"12","key":"10.1016\/j.maturitas.2004.07.013_bib31","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1016\/0026-0495(94)90002-7","article-title":"Copper deficiency secondary to a copper transport defect: a new copper metabolic disturbance","volume":"43","author":"Bunchman Al","year":"1994","journal-title":"Metabolism"},{"issue":"1","key":"10.1016\/j.maturitas.2004.07.013_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02789074","article-title":"The relationship of nutritional copper to the development of postmenopausal osteoporosis","volume":"48","author":"Yee","year":"1995","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.maturitas.2004.07.013_bib33","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0009-8981(99)00151-5","article-title":"Comparison of biochemical markers of bone remodeling in the assessment of the effects of alendronate on bone in postmenopausal osteoporosis","volume":"288","author":"Stepan","year":"1999","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.maturitas.2004.07.013_bib34","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0002-9343(96)00387-7","article-title":"Hormone replacement therapy in postmenopausal women: urinary N-telopeptide of type I collagen monitors therapeutic effects and predicts response of bone mineral density","volume":"102","author":"Chesnut","year":"1997","journal-title":"Am J Med"},{"key":"10.1016\/j.maturitas.2004.07.013_bib35","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S8756-3282(99)00087-3","article-title":"A model to monitor the efficacy of alendronate treatment in women with osteoporosis using a biochemical marker of bone turnover","volume":"24","author":"Garnero","year":"1999","journal-title":"Bone"},{"issue":"1","key":"10.1016\/j.maturitas.2004.07.013_bib36","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/S8756-3282(03)00168-6","article-title":"Biochemical markers for prediction of 4-year response in bone mass during bisphosphanate treatment for prevention of postmenopausal osteoporosis","volume":"33","author":"Ravn","year":"2003","journal-title":"Bone"},{"key":"10.1016\/j.maturitas.2004.07.013_bib37","doi-asserted-by":"crossref","first-page":"2617","DOI":"10.1001\/archinte.1997.00440430099012","article-title":"Treatment with alendronate prevents fractures in women at highest risk: results from the Fracture Intervention Trial","volume":"157","author":"Ensrud","year":"1997","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.maturitas.2004.07.013_bib38","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1359\/jbmr.2000.15.8.1537","article-title":"The predictive value of biochemical markers of bone turnover for bone mineral density in postmenopausal Japanese women","volume":"15","author":"Chaki","year":"2000","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.maturitas.2004.07.013_bib39","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1359\/jbmr.1999.14.8.1404","article-title":"Biochemical markers of bone turnover and prediction of hip bone loss in older women: the study of osteoporotic fractures","volume":"14","author":"Bauer","year":"1999","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.maturitas.2004.07.013_bib40","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0378-5122(03)00084-7","article-title":"Relationship between PTH, sex steroid and bone turnover marker measurements and bone density in recently postmenopausal women","volume":"45","author":"Garcia-Perez","year":"2003","journal-title":"Maturitas"},{"key":"10.1016\/j.maturitas.2004.07.013_bib41","first-page":"3537","article-title":"Early changes in serum N-telopeptide and C-telopeptide cross-linked collagen type I predict long-term response to alendronate therapy in elderly women","volume":"85","author":"Greenspan","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.maturitas.2004.07.013_bib42","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0167-4943(99)00036-9","article-title":"The NTX assay in the follow-up of the osteoporotic patients: 3 years of alendronate treatment","volume":"29","author":"Maugeri","year":"1999","journal-title":"Arch Gerontorol Geriatr"},{"key":"10.1016\/j.maturitas.2004.07.013_bib43","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/BF00298992","article-title":"Acute effect of bisphosphanates on a new marker of bone resorption","volume":"57","author":"Pedrazzoni","year":"1995","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.maturitas.2004.07.013_bib44","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/jbmr.5650100418","article-title":"Different effects of bisphosphanate and estrogen therapy on free and peptide-bound bone cross-links excretion","volume":"10","author":"Garnero","year":"1995","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.maturitas.2004.07.013_bib45","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0531-5131(01)00588-X","article-title":"Zincuria and zincemia in postmenopausal osteoporosis","volume":"1237","author":"Contreras","year":"2002","journal-title":"Int Congress Ser"}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512204002725?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512204002725?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T08:40:14Z","timestamp":1759912814000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512204002725"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["S0378512204002725"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2004.07.013","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2005,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of calcitonin on biochemical markers and zinc excretion in postmenopausal osteoporosis","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2004.07.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}