{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T03:52:57Z","timestamp":1778903577557,"version":"3.51.4"},"reference-count":16,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.maturitas.2007.02.015","type":"journal-article","created":{"date-parts":[[2007,3,20]],"date-time":"2007-03-20T06:51:22Z","timestamp":1174373482000},"page":"77-80","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Routes of delivery for progesterone and progestins"],"prefix":"10.1016","volume":"57","author":[{"given":"Regine","family":"Sitruk-Ware","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"13","key":"10.1016\/j.maturitas.2007.02.015_bib1","doi-asserted-by":"crossref","first-page":"865","DOI":"10.2165\/00002512-200421130-00004","article-title":"New progestogens: a review of their effects in perimenopausal and postmenopausal women","volume":"21","author":"Sitruk-Ware","year":"2004","journal-title":"Drugs Aging"},{"issue":"14","key":"10.1016\/j.maturitas.2007.02.015_bib2","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/S1359-6446(05)03499-9","article-title":"Delivery options for contraceptives","volume":"10","author":"Sitruk-Ware","year":"2005","journal-title":"Drug Discov Today"},{"issue":"4","key":"10.1016\/j.maturitas.2007.02.015_bib3","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/humupd\/5.4.365","article-title":"Transvaginal progesterone: evidence for a new functional \u2018portal system\u2019 flowing from the vagina to the uterus","volume":"5","author":"Cicinelli","year":"1999","journal-title":"Hum Reprod Update"},{"issue":"3","key":"10.1016\/j.maturitas.2007.02.015_bib4","first-page":"403","article-title":"Direct transport of progesterone from vagina to uterus","volume":"95","author":"Cicinelli","year":"2000","journal-title":"Obstet Gynecol"},{"issue":"Suppl. 1","key":"10.1016\/j.maturitas.2007.02.015_bib5","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1093\/humrep\/15.suppl_1.149","article-title":"Vaginal progesterone in menopause: Crinone 4% in cyclical and constant combined regimens","volume":"15","author":"de Ziegler","year":"2000","journal-title":"Hum Reprod"},{"issue":"February (2)","key":"10.1016\/j.maturitas.2007.02.015_bib6","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/HUMREP\/11.2.357","article-title":"Morphometric, immunohistological and three-dimensional evaluation of the endometrium of menopausal women treated by oestrogen and Crinone, a new slow-release vaginal progesterone","volume":"11","author":"Casanas-Roux","year":"1996","journal-title":"Hum Reprod"},{"issue":"10","key":"10.1016\/j.maturitas.2007.02.015_bib7","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1093\/humrep\/15.10.2093","article-title":"Prospective randomized trial to evaluate the efficacy of a vaginal ring releasing progesterone for IVF and oocyte donation","volume":"15","author":"Zegers-Hochschild","year":"2000","journal-title":"Hum Reprod"},{"issue":"1","key":"10.1016\/j.maturitas.2007.02.015_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fertnstert.2004.01.025","article-title":"Why consider vaginal drug administration?","volume":"82","author":"Alexander","year":"2004","journal-title":"Fertil Steril"},{"issue":"November (5)","key":"10.1016\/j.maturitas.2007.02.015_bib9","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/S0015-0282(02)03365-4","article-title":"Vaginal rings delivering progesterone and estradiol may be a new method of hormone replacement therapy","volume":"78","author":"Maruo","year":"2002","journal-title":"Fertil Steril"},{"key":"10.1016\/j.maturitas.2007.02.015_bib10","series-title":"Contraception. Newer Pharmacological Agents, Devices, and Delivery Systems","first-page":"101","article-title":"Transdermal contraceptive systems: innovative technology for the twenty-first century","author":"Croxatto","year":"1992"},{"key":"10.1016\/j.maturitas.2007.02.015_bib11","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S0039-128X(03)00140-5","article-title":"Nestorone\u00ae clinical applications for contraception and HRT","volume":"68","author":"Sitruk-Ware","year":"2003","journal-title":"Steroids"},{"issue":"May\u2013June (3)","key":"10.1016\/j.maturitas.2007.02.015_bib12","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00042192-200310030-00012","article-title":"Effect of low-dose transdermal E2\/NETA on the reduction of postmenopausal bone loss in women","volume":"10","author":"Rubinacci","year":"2003","journal-title":"Menopause"},{"issue":"2","key":"10.1016\/j.maturitas.2007.02.015_bib13","first-page":"170","article-title":"Endometrial safety of a transdermal sequential estradiol-levonorgestrel combination","volume":"5","author":"Sturdee","year":"2002","journal-title":"Climacteric"},{"issue":"2","key":"10.1016\/j.maturitas.2007.02.015_bib14","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3109\/07853899009147248","article-title":"Levonorgestrel-releasing intrauterine device","volume":"22","author":"Luukkainen","year":"1990","journal-title":"Ann Med"},{"issue":"2","key":"10.1016\/j.maturitas.2007.02.015_bib15","first-page":"171","article-title":"The Levonorgestrel intrauterine system: long-term contraception and therapeutic effects","volume":"1","author":"Sitruk-Ware","year":"2005","journal-title":"Womens Health"},{"issue":"4","key":"10.1016\/j.maturitas.2007.02.015_bib16","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1080\/13697130400012270","article-title":"the acceptability of a small intrauterine progestogen-releasing system for continuous combined hormone therapy in early postmenopausal women","volume":"7","author":"Sturdee","year":"2004","journal-title":"Climacteric"}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512207000771?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512207000771?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T08:43:18Z","timestamp":1759912998000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512207000771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0378512207000771"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2007.02.015","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Routes of delivery for progesterone and progestins","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2007.02.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}