{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:01:14Z","timestamp":1761512474904,"version":"build-2065373602"},"reference-count":34,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.maturitas.2007.09.014","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:04:21Z","timestamp":1196096661000},"page":"83-90","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Reduced frontal perfusion in depressed postmenopausal women: A SPECT study with WCST"],"prefix":"10.1016","volume":"59","author":[{"given":"Wei-Jen","family":"Yao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsien-An","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen-Kuang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-Hwa","family":"Chou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan-Tair","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chin-Yin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Dun","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.maturitas.2007.09.014_bib1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/00006231-200503000-00004","article-title":"The use of single photon emission computed tomography in depressive disorders","volume":"26","author":"Smith","year":"2005","journal-title":"Nucl Med Commun"},{"year":"1992","series-title":"The ICD-10 classification of mental and behavioural disorders","author":"World Health Organization","key":"10.1016\/j.maturitas.2007.09.014_bib2"},{"year":"1994","series-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","key":"10.1016\/j.maturitas.2007.09.014_bib3"},{"key":"10.1016\/j.maturitas.2007.09.014_bib4","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1097\/00006231-200012000-00005","article-title":"Diffuse cortical reduction of neuronal activity in unipolar major depression: a retrospective analysis of 337 patients and 321 controls","volume":"21","author":"Nikolaus","year":"2000","journal-title":"Nucl Med Commun"},{"key":"10.1016\/j.maturitas.2007.09.014_bib5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1001\/archpsyc.1985.01790280019002","article-title":"Cerebral metabolic rates for glucose in mood disorders. Studies with positron emission tomography and fluorodeoxyglucose F 18","volume":"42","author":"Baxter","year":"1985","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib6","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1017\/S003329170003806X","article-title":"The anatomy of melancholia-focal abnormalities of cerebral blood flow in major depression","volume":"22","author":"Bench","year":"1992","journal-title":"Psychol Med"},{"key":"10.1016\/j.maturitas.2007.09.014_bib7","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1017\/S0033291700025368","article-title":"Regional cerebral blood flow in depression measured by positron emission tomography: the relationship with clinical dimensions","volume":"23","author":"Bench","year":"1993","journal-title":"Psychol Med"},{"key":"10.1016\/j.maturitas.2007.09.014_bib8","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0925-4927(02)00103-8","article-title":"Cerebral blood flow in depressed patients: a methodological comparison of statistical parametric mapping and region of interest analyses","volume":"122","author":"Bonne","year":"2003","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.maturitas.2007.09.014_bib9","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1038\/386824a0","article-title":"Subgenual prefrontal cortex abnormalities in mood disorders","volume":"386","author":"Drevets","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.maturitas.2007.09.014_bib10","first-page":"608","article-title":"Hypofrontality and negative symptoms in major depressive disorder","volume":"39","author":"Galynker","year":"1998","journal-title":"J Nucl Med"},{"key":"10.1016\/j.maturitas.2007.09.014_bib11","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1006\/nimg.2001.0787","article-title":"Frontal cerebral perfusion dysfunction in elderly late-onset major depression assessed by (TC)-T-99M-HMPAO SPECT","volume":"14","author":"Navarro","year":"2001","journal-title":"Neuroimage"},{"key":"10.1016\/j.maturitas.2007.09.014_bib12","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1006\/nimg.2002.1051","article-title":"Normalization of frontal cerebral perfusion in remitted elderly major depression: a 12-month follow-up SPECT study","volume":"16","author":"Navarro","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.maturitas.2007.09.014_bib13","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1176\/ajp.147.10.1313","article-title":"Left prefrontal glucose hypometabolism in the depressed state: a confirmation","volume":"147","author":"Martinot","year":"1990","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib14","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1017\/S0033291700036151","article-title":"Changes in regional cerebral blood flow on recovery from depression","volume":"25","author":"Bench","year":"1995","journal-title":"Psychol Med"},{"key":"10.1016\/j.maturitas.2007.09.014_bib15","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1192\/bjp.164.4.513","article-title":"Affective symptoms in women attending a menopause clinic","volume":"164","author":"Hay","year":"1994","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib16","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0140-6736(87)92026-5","article-title":"Effect of oestrogen and testosterone implants on psychological disorders in the climacteric","volume":"1","author":"Montgomery","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.maturitas.2007.09.014_bib17","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/S0140-6736(96)91414-2","article-title":"Transdermal oestrogen for treatment of severe postnatal depression","volume":"347","author":"Gregoire","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.maturitas.2007.09.014_bib18","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1007\/s002590050316","article-title":"Evaluation of brain perfusion with technetium-99m bicisate single-photon emission tomography in patients with depressive disorder before and after drug treatment","volume":"25","author":"Kocmur","year":"1998","journal-title":"Eur J Nucl Med"},{"key":"10.1016\/j.maturitas.2007.09.014_bib19","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1001\/archpsyc.58.6.529","article-title":"Efficacy of estradiol for the treatment of depressive disorders in perimenopausal women: a double-blind, randomized, placebo-controlled trial","volume":"58","author":"Soares","year":"2001","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib20","first-page":"191","article-title":"Technetium-99m d,l-HM-PAO: a new radiopharmaceutical for SPECT imaging of regional cerebral blood perfusion","volume":"28","author":"Neirinckx","year":"1987","journal-title":"J Nucl Med"},{"key":"10.1016\/j.maturitas.2007.09.014_bib21","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0925-4927(01)00086-5","article-title":"Tc-99m HMPAO brain perfusion SPECT in drug-free obsessive-compulsive patients without depression","volume":"107","author":"Alptekin","year":"2001","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.maturitas.2007.09.014_bib22","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0140-6736(98)05352-5","article-title":"The menopause","volume":"353","author":"Greendale","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.maturitas.2007.09.014_bib23","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/00003081-197612000-00005","article-title":"Hormonal dynamics associated with the menopause","volume":"19","author":"Judd","year":"1976","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.maturitas.2007.09.014_bib24","unstructured":"Christoff K. SPM99: Protocols, Tools, and Documentation. http:\/\/www-psych.stanford.edu\/\u223ckalina\/SPM99\/."},{"key":"10.1016\/j.maturitas.2007.09.014_bib25","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1097\/01.grf.0000129918.00756.d5","article-title":"Menopause and mood","volume":"47","author":"Soares","year":"2004","journal-title":"Clin Obstet Gynecol"},{"key":"10.1016\/j.maturitas.2007.09.014_bib26","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1124\/mol.104.004465","article-title":"Estrogen receptor activation of phosphoinositide-3 kinase, Akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects","volume":"67","author":"Stirone","year":"2005","journal-title":"Mol Pharmacol"},{"key":"10.1016\/j.maturitas.2007.09.014_bib27","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0378-5122(03)00144-0","article-title":"Influence of hormonal replacement therapy on the regional cerebral blood flow in postmenopausal women","volume":"46","author":"Slopien","year":"2003","journal-title":"Maturitas"},{"key":"10.1016\/j.maturitas.2007.09.014_bib28","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.biopsych.2005.04.047","article-title":"Alteration in estrogen receptor alpha mRNA levels in frontal cortex and hippocampus of patients with major mental illness","volume":"58","author":"Perlman","year":"2005","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib29","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1176\/ajp.144.2.151","article-title":"Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia","volume":"144","author":"Volkow","year":"1987","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib30","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/archpsyc.1992.01820120047007","article-title":"Negative symptoms and hypofrontality in chronic schizophrenia","volume":"49","author":"Wolkin","year":"1992","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib31","first-page":"52","article-title":"Negative symptoms in patients with Alzheimer's disease","volume":"3","author":"Galynker","year":"1995","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib32","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/0006-3223(96)84479-9","article-title":"Regional cerebral blood flow in patients with dementia of Alzheimer's type: relationship to psychiatric symptoms","volume":"39","author":"Galynker","year":"1996","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib33","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0006-3223(90)90549-H","article-title":"Hypofrontality and cognitive impairment in schizophrenia: dynamic single-photon tomography and neuropsychological assessment of schizophrenic brain function","volume":"27","author":"Paulman","year":"1990","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.maturitas.2007.09.014_bib34","first-page":"929","article-title":"Paralimbic hypoperfusion in unipolar depression","volume":"35","author":"Mayberg","year":"1994","journal-title":"J Nucl Med"}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512207002708?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512207002708?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T08:45:48Z","timestamp":1759913148000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512207002708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["S0378512207002708"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2007.09.014","relation":{},"ISSN":["0378-5122"],"issn-type":[{"type":"print","value":"0378-5122"}],"subject":[],"published":{"date-parts":[[2008,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reduced frontal perfusion in depressed postmenopausal women: A SPECT study with WCST","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2007.09.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}