{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T16:28:07Z","timestamp":1789921687856,"version":"4.0.1"},"reference-count":53,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1016\/j.maturitas.2008.04.004","type":"journal-article","created":{"date-parts":[[2008,5,30]],"date-time":"2008-05-30T06:04:07Z","timestamp":1212127447000},"page":"108-121","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"title":["Risk factors for onset of menopausal symptoms"],"prefix":"10.1016","volume":"60","author":[{"given":"S\u00e9verine","family":"Sabia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agn\u00e8s","family":"Fournier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Mesrine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Christine","family":"Boutron-Ruault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Clavel-Chapelon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.maturitas.2008.04.004_bib1","doi-asserted-by":"crossref","unstructured":"National Institutes of Health State-of-the-Science Conference statement: management of menopause-related symptoms. Ann Intern Med 2005;142(June (12 Pt 1)):1003\u201313.","DOI":"10.7326\/0003-4819-142-12_Part_1-200506210-00117"},{"issue":"September (5)","key":"10.1016\/j.maturitas.2008.04.004_bib2","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1093\/aje\/152.5.463","article-title":"Relation of demographic and lifestyle factors to symptoms in a multi-racial\/ethnic population of women 40\u201355 years of age","volume":"152","author":"Gold","year":"2000","journal-title":"Am J Epidemiol"},{"issue":"April (4)","key":"10.1016\/j.maturitas.2008.04.004_bib3","first-page":"403","article-title":"Estrogen levels in postmenopausal women with hot flashes","volume":"59","author":"Erlik","year":"1982","journal-title":"Obstet Gynecol"},{"issue":"January (1)","key":"10.1016\/j.maturitas.2008.04.004_bib4","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1089\/152460901750067133","article-title":"Hot flashes in the late reproductive years: risk factors for Africa American and Caucasian women","volume":"10","author":"Freeman","year":"2001","journal-title":"J Womens Health Gend Based Med"},{"issue":"December (6)","key":"10.1016\/j.maturitas.2008.04.004_bib5","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1016\/S0002-9378(03)00872-X","article-title":"Menopause-related symptoms: what are the background factors? A prospective population-based cohort study of Swedish women (The Women's Health in Lund Area study)","volume":"189","author":"Li","year":"2003","journal-title":"Am J Obstet Gynecol"},{"issue":"July (1)","key":"10.1016\/j.maturitas.2008.04.004_bib6","first-page":"29","article-title":"Risk factors for menopausal hot flashes","volume":"84","author":"Schwingl","year":"1994","journal-title":"Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.maturitas.2008.04.004_bib7","first-page":"43","article-title":"Sociodemographic characteristics, biological factors, and symptom reporting in midlife women","volume":"5","author":"Wilbur","year":"1998","journal-title":"Menopause"},{"issue":"June (2)","key":"10.1016\/j.maturitas.2008.04.004_bib8","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0378-5122(98)00004-8","article-title":"Physical exercise and vasomotor symptoms in postmenopausal women","volume":"29","author":"Ivarsson","year":"1998","journal-title":"Maturitas"},{"issue":"May (3)","key":"10.1016\/j.maturitas.2008.04.004_bib9","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1097\/01.GME.0000163869.89878.D9","article-title":"A longitudinal study of the predictors of prevalence and severity of symptoms commonly associated with menopause","volume":"12","author":"Ford","year":"2005","journal-title":"Menopause"},{"issue":"November (9)","key":"10.1016\/j.maturitas.2008.04.004_bib10","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1089\/jwh.1998.7.1149","article-title":"Predictors of menopausal hot flashes","volume":"7","author":"Staropoli","year":"1998","journal-title":"J Womens Health"},{"issue":"January (2)","key":"10.1016\/j.maturitas.2008.04.004_bib11","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.maturitas.2005.03.007","article-title":"Cigarette smoking, estrogen levels, and hot flashes in midlife women","volume":"53","author":"Gallicchio","year":"2006","journal-title":"Maturitas"},{"issue":"July (4)","key":"10.1016\/j.maturitas.2008.04.004_bib12","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1097\/01.GME.0000155200.80687.BE","article-title":"Hot flushes during the menopause transition: a longitudinal study in Australian-born women","volume":"12","author":"Guthrie","year":"2005","journal-title":"Menopause"},{"issue":"June (5)","key":"10.1016\/j.maturitas.2008.04.004_bib13","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1089\/154099903766651586","article-title":"Risk factors for hot flashes in midlife women","volume":"12","author":"Whiteman","year":"2003","journal-title":"J Womens Health (Larchmt)"},{"issue":"November (10)","key":"10.1016\/j.maturitas.2008.04.004_bib14","doi-asserted-by":"crossref","first-page":"805","DOI":"10.7326\/0003-4819-137-10-200211190-00009","article-title":"Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials","volume":"137","author":"Kronenberg","year":"2002","journal-title":"Ann Intern Med"},{"issue":"Suppl. 1","key":"10.1016\/j.maturitas.2008.04.004_bib15","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1093\/ije\/26.suppl_1.S6","article-title":"The EPIC Project: rationale and study design. European Prospective Investigation into Cancer and Nutrition","volume":"26","author":"Riboli","year":"1997","journal-title":"Int J Epidemiol"},{"issue":"Suppl. 1","key":"10.1016\/j.maturitas.2008.04.004_bib16","doi-asserted-by":"crossref","first-page":"S128","DOI":"10.1093\/ije\/26.suppl_1.S128","article-title":"Relative validity and reproducibility of a French dietary history questionnaire","volume":"26","author":"van Liere","year":"1997","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.maturitas.2008.04.004_bib17","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1365-277X.1995.tb00296.x","article-title":"Estimation of food portion size using photographs: validity, strengths, weaknesses and recommendations","volume":"8","author":"Lucas","year":"1995","journal-title":"J Human Nutr Diet"},{"issue":"4","key":"10.1016\/j.maturitas.2008.04.004_bib18","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.maturitas.2007.09.012","article-title":"Risk of onset of menopausal symptoms in periods surrounding menopause","volume":"58","author":"Sabia","year":"2007","journal-title":"Maturitas"},{"issue":"April (8)","key":"10.1016\/j.maturitas.2008.04.004_bib19","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.phytochem.2004.03.005","article-title":"Dietary phytoestrogens and health","volume":"65","author":"Cornwell","year":"2004","journal-title":"Phytochemistry"},{"issue":"August (5)","key":"10.1016\/j.maturitas.2008.04.004_bib20","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s00394-004-0523-x","article-title":"Regional dietary habits of French women born between 1925 and 1950","volume":"44","author":"Kesse","year":"2005","journal-title":"Eur J Nutr"},{"issue":"July (7)","key":"10.1016\/j.maturitas.2008.04.004_bib21","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.2105\/AJPH.2005.066936","article-title":"Longitudinal analysis of the association between vasomotor symptoms and race\/ethnicity across the menopausal transition: study of women's health across the nation","volume":"96","author":"Gold","year":"2006","journal-title":"Am J Public Health"},{"issue":"June (6)","key":"10.1016\/j.maturitas.2008.04.004_bib22","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.contraception.2006.01.016","article-title":"Menstrual cycle bleeding patterns in cigarette smokers","volume":"73","author":"Grossman","year":"2006","journal-title":"Contraception"},{"issue":"January (1 Suppl.)","key":"10.1016\/j.maturitas.2008.04.004_bib23","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1093\/ajcn\/45.1.277","article-title":"Adipose tissue as a source of hormones","volume":"45","author":"Siiteri","year":"1987","journal-title":"Am J Clin Nutr"},{"issue":"January (1)","key":"10.1016\/j.maturitas.2008.04.004_bib24","first-page":"78","article-title":"Adiposity and reporting of vasomotor symptoms among midlife women: the study of women's health across the nation","volume":"167","author":"Thurston","year":"2008","journal-title":"Am J Epidemiol"},{"issue":"May (5)","key":"10.1016\/j.maturitas.2008.04.004_bib25","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s001980200043","article-title":"Bone mass, bone metabolism, gonadal status and body mass index","volume":"13","author":"Rico","year":"2002","journal-title":"Osteoporos Int"},{"issue":"August (2 Pt 1)","key":"10.1016\/j.maturitas.2008.04.004_bib26","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1097\/01.AOG.0000270153.59102.40","article-title":"Symptoms associated with menopausal transition and reproductive hormones in midlife women","volume":"110","author":"Freeman","year":"2007","journal-title":"Obstet Gynecol"},{"issue":"November (6)","key":"10.1016\/j.maturitas.2008.04.004_bib27","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1093\/humupd\/dmm022","article-title":"New findings from non-linear longitudinal modelling of menopausal hormone changes","volume":"13","author":"Dennerstein","year":"2007","journal-title":"Hum Reprod Update"},{"issue":"April (4)","key":"10.1016\/j.maturitas.2008.04.004_bib28","first-page":"741","article-title":"Estrogen and sex hormone-binding globulin levels in nulliparous and parous women","volume":"74","author":"Bernstein","year":"1985","journal-title":"J Natl Cancer Inst"},{"issue":"September (9)","key":"10.1016\/j.maturitas.2008.04.004_bib29","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1289\/ehp.97105994","article-title":"Factors associated with serum levels of estradiol and sex hormone-binding globulin among premenopausal Japanese women","volume":"105","author":"Nagata","year":"1997","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.maturitas.2008.04.004_bib30","first-page":"139","article-title":"Study Investigators. The effect of 20\u03bcg ethinyl estradiol\/1mg norethindrone acetate (Minestrin\u2122), a low-dose oral contraceptive, on vaginal bleeding patterns, hot flashes, and quality of life in symptomatic perimenopausal women","volume":"4","author":"Casper","year":"1997","journal-title":"Menopause"},{"key":"10.1016\/j.maturitas.2008.04.004_bib31","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0378-5122(94)90047-7","article-title":"Very low estrogen desogestrel contraceptive in perimenopausal hormonal replacement","volume":"18","author":"Porcile","year":"1994","journal-title":"Maturitas"},{"key":"10.1016\/j.maturitas.2008.04.004_bib32","first-page":"15","article-title":"Hormone replacement therapy in perimenopausal women with a triphasic contraceptive compound: a three-year prospective study","volume":"30","author":"Shargil","year":"1985","journal-title":"Int J Fertil"},{"issue":"November (6)","key":"10.1016\/j.maturitas.2008.04.004_bib33","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s11940-004-0006-7","article-title":"Menstrual migraine","volume":"6","author":"Mannix","year":"2004","journal-title":"Curr Treat Options Neurol"},{"issue":"January (9406)","key":"10.1016\/j.maturitas.2008.04.004_bib34","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0140-6736(04)15440-8","article-title":"Migraine","volume":"363","author":"Silberstein","year":"2004","journal-title":"Lancet"},{"issue":"January (1)","key":"10.1016\/j.maturitas.2008.04.004_bib35","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1001\/archpsyc.60.1.29","article-title":"Depression and its influence on reproductive endocrine and menstrual cycle markers associated with perimenopause: the Harvard Study of Moods and Cycles","volume":"60","author":"Harlow","year":"2003","journal-title":"Arch Gen Psychiatry"},{"issue":"May (3)","key":"10.1016\/j.maturitas.2008.04.004_bib36","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/01.GME.0000142440.49698.B7","article-title":"The role of anxiety and hormonal changes in menopausal hot flashes","volume":"12","author":"Freeman","year":"2005","journal-title":"Menopause"},{"issue":"May (5)","key":"10.1016\/j.maturitas.2008.04.004_bib37","first-page":"452","article-title":"Prevalence of night sweats in primary care patients: an OKPRN and TAFP-Net collaborative study","volume":"51","author":"Mold","year":"2002","journal-title":"J Fam Pract"},{"issue":"September (3 Pt 2)","key":"10.1016\/j.maturitas.2008.04.004_bib38","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1097\/01.AOG.0000189718.07777.c1","article-title":"Night sweats and elevated follicle-stimulating hormone levels while taking selective serotonin reuptake inhibitors","volume":"108","author":"Shahine","year":"2006","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.maturitas.2008.04.004_bib39","doi-asserted-by":"crossref","first-page":"83","DOI":"10.2165\/00024677-200605020-00002","article-title":"Serotonergic agents as an alternative to hormonal therapy for the treatment of menopausal vasomotor symptoms","volume":"5","author":"Stearns","year":"2006","journal-title":"Treat Endocrinol"},{"issue":"January (1)","key":"10.1016\/j.maturitas.2008.04.004_bib40","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-5122(01)00256-0","article-title":"Androgens and estrogens in relation to hot flushes during the menopausal transition","volume":"41","author":"Overlie","year":"2002","journal-title":"Maturitas"},{"issue":"October (4)","key":"10.1016\/j.maturitas.2008.04.004_bib41","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1152\/physrev.00014.2002","article-title":"Estrogen and thyroid hormone receptor interactions: physiological flexibility by molecular specificity","volume":"82","author":"Vasudevan","year":"2002","journal-title":"Physiol Rev"},{"issue":"February (1)","key":"10.1016\/j.maturitas.2008.04.004_bib42","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/gye.17.1.79.85","article-title":"Thyroid function and postmenopause","volume":"17","author":"Schindler","year":"2003","journal-title":"Gynecol Endocrinol"},{"issue":"October (Suppl. 3)","key":"10.1016\/j.maturitas.2008.04.004_bib43","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.1007\/s10072-004-0260-1","article-title":"Contributions of biochemistry to the pathogenesis of primary headaches","volume":"25","author":"D\u2019Andrea","year":"2004","journal-title":"Neurol Sci"},{"issue":"March (1\u20133)","key":"10.1016\/j.maturitas.2008.04.004_bib44","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.ejphar.2005.12.044","article-title":"Histamine receptors are hot in immunopharmacology","volume":"533","author":"Akdis","year":"2006","journal-title":"Eur J Pharmacol"},{"issue":"September (3)","key":"10.1016\/j.maturitas.2008.04.004_bib45","doi-asserted-by":"crossref","first-page":"C1120","DOI":"10.1152\/ajpcell.00286.2006","article-title":"Cellular recruitment and cytokine generation in a rat model of allergic lung inflammation are differentially modulated by progesterone and estradiol","volume":"293","author":"de Oliveira","year":"2007","journal-title":"Am J Physiol Cell Physiol"},{"issue":"September (5)","key":"10.1016\/j.maturitas.2008.04.004_bib46","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/00006199-200309000-00008","article-title":"Menopausal hot flash frequency changes in response to experimental manipulation of blood glucose","volume":"52","author":"Dormire","year":"2003","journal-title":"Nurs Res"},{"issue":"March (1)","key":"10.1016\/j.maturitas.2008.04.004_bib47","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3109\/13697139909025557","article-title":"Hot flushes and other menopausal symptoms in relation to soy product intake in Japanese women","volume":"2","author":"Nagata","year":"1999","journal-title":"Climacteric"},{"issue":"April (8)","key":"10.1016\/j.maturitas.2008.04.004_bib48","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1093\/aje\/153.8.790","article-title":"Soy product intake and hot flashes in Japanese women: results from a community-based prospective study","volume":"153","author":"Nagata","year":"2001","journal-title":"Am J Epidemiol"},{"issue":"March (6)","key":"10.1016\/j.maturitas.2008.04.004_bib49","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/jnci\/djk096","article-title":"Dietary lignan intake and postmenopausal breast cancer risk by estrogen and progesterone receptor status","volume":"99","author":"Touillaud","year":"2007","journal-title":"J Natl Cancer Inst"},{"issue":"November (3)","key":"10.1016\/j.maturitas.2008.04.004_bib50","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0738-3991(98)00143-8","article-title":"An evaluation of a health education intervention for mid-aged women: five year follow-up of effects upon knowledge, impact of menopause and health","volume":"38","author":"Hunter","year":"1999","journal-title":"Patient Educ Couns"},{"issue":"June (2)","key":"10.1016\/j.maturitas.2008.04.004_bib51","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0378-5122(98)00020-6","article-title":"A validation study on status and age of natural menopause reported in the E3N cohort","volume":"29","author":"Clavel-Chapelon","year":"1998","journal-title":"Maturitas"},{"issue":"July (4)","key":"10.1016\/j.maturitas.2008.04.004_bib52","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1097\/gme.0b013e318046eb4a","article-title":"Symptoms, menopause status, and country differences: a comparative analysis from DAMES","volume":"14","author":"Obermeyer","year":"2007","journal-title":"Menopause"},{"issue":"December (Suppl. 12B)","key":"10.1016\/j.maturitas.2008.04.004_bib53","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.amjmed.2005.09.031","article-title":"Symptoms during the perimenopause: prevalence, severity, trajectory, and significance in women's lives","volume":"118","author":"Woods","year":"2005","journal-title":"Am J Med"}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512208001151?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512208001151?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T08:44:31Z","timestamp":1759913071000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512208001151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":53,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["S0378512208001151"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2008.04.004","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2008,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk factors for onset of menopausal symptoms","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2008.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}