{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T19:14:49Z","timestamp":1780514089837,"version":"3.54.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.maturitas.2015.08.001","type":"journal-article","created":{"date-parts":[[2015,8,12]],"date-time":"2015-08-12T07:34:41Z","timestamp":1439364881000},"page":"342-345","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":79,"title":["Genitourinary syndrome of menopause and the use of laser therapy"],"prefix":"10.1016","volume":"82","author":[{"given":"Juana","family":"Hutchinson-Colas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saya","family":"Segal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.maturitas.2015.08.001_bib0130","doi-asserted-by":"crossref","first-page":"2865","DOI":"10.1111\/jsm.12686","article-title":"Genitourinary syndrome of menopause: new terminology for vulvovaginal atrophy from the International Society for the Study of Women's Sexual Health and the North American Menopause Society","volume":"11","author":"Portman","year":"2014","journal-title":"J. Sex. Med."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0135","doi-asserted-by":"crossref","DOI":"10.1111\/anae.12510","article-title":"The ageing anaesthetist","author":"Redfern","year":"2014","journal-title":"Anaesthesia"},{"issue":"1","key":"10.1016\/j.maturitas.2015.08.001_bib0140","doi-asserted-by":"crossref","first-page":"87","DOI":"10.4065\/mcp.2009.0413","article-title":"Vulvovaginal atrophy","volume":"85","author":"MacBride","year":"2010","journal-title":"Mayo Clin. Proc."},{"issue":"1","key":"10.1016\/j.maturitas.2015.08.001_bib0145","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3109\/13697137.2013.871696","article-title":"Impact of vulvovaginal atrophy on sexual health and quality of life at postmenopause","volume":"17","author":"Nappi","year":"2014","journal-title":"Climacteric"},{"issue":"1","key":"10.1016\/j.maturitas.2015.08.001_bib0150","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3109\/13697137.2011.647840","article-title":"Vaginal Health: Insights Views & Attitudes (VIVA): results from an international survey","volume":"15","author":"Nappi","year":"2012","journal-title":"Climacteric"},{"key":"10.1016\/j.maturitas.2015.08.001_bib0155","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1111\/j.1743-6109.2009.01692.x","article-title":"Vulvovaginal atrophy: current and future therapies (CME)","volume":"7","author":"Ibe","year":"2010","journal-title":"J. Sex. Med."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0160","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.maturitas.2010.08.001","article-title":"Women's voices in the menopause: results from an international survey on vaginal atrophy","volume":"67","author":"Nappi","year":"2010","journal-title":"Maturitas"},{"issue":"4 Pt 1","key":"10.1016\/j.maturitas.2015.08.001_bib0165","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1097\/gme.0b013e31815a5168","article-title":"Vulvovaginal atrophy is strongly associated with female sexual dysfunction among sexually active postmenopausal women","volume":"15","author":"Levine","year":"2008","journal-title":"Menopause"},{"key":"10.1016\/j.maturitas.2015.08.001_bib0170","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1111\/jsm.12235","article-title":"The CLOSER (CLarifying Vaginal Atrophy's Impact on SEx and Relationships) survey: implications of vaginal discomfort in postmenopausal women and in male partners","volume":"10","author":"Nappi","year":"2013","journal-title":"J. Sex. Med."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0175","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3390\/jpm5020050","article-title":"Atrophic vaginitis in breast cancer survivors: a difficult survivorship issue","volume":"5","author":"Lester","year":"2015","journal-title":"J. Pers. Med."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0180","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3109\/13697137.2013.819327","article-title":"Prevalence of menopausal symptoms and their influence on adherence in women with breast cancer","volume":"17","author":"Kyvernitakis","year":"2011","journal-title":"Climacteric"},{"issue":"September (9)","key":"10.1016\/j.maturitas.2015.08.001_bib0185","first-page":"888","article-title":"Management of symptomatic vulvovaginal atrophy: 2013 position statement of the North American Menopause Society","volume":"20","year":"2013","journal-title":"Menopause"},{"issue":"January (1)","key":"10.1016\/j.maturitas.2015.08.001_bib0190","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/gme.0b013e31821f92df","article-title":"Management of vulvovaginal atrophy-related sexual dysfunction in postmenopausal women: an up-to-date review","volume":"19","author":"Tan","year":"2012","journal-title":"Menopause: J. N. Am. Menopause Soc."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0195","unstructured":"US Food and Drug Administration letter to Paolo Peruzzi. September 5, 2014. www.accessdata.fda.gov\/cdrh_docs\/pdf13\/K133895.pdf (accessed 23.07.15)."},{"issue":"January","key":"10.1016\/j.maturitas.2015.08.001_bib0200","article-title":"Histological study on the effects of microablative fractional CO2 laser on atrophic vaginal tissue: an ex vivo study","volume":"20","author":"Salvatore","year":"2015","journal-title":"Menopause"},{"issue":"3","key":"10.1016\/j.maturitas.2015.08.001_bib0205","first-page":"150","article-title":"Microablative fractional CO2 laser improves dyspareunia related to vulvovaginal atrophy: a pilot study","volume":"6","author":"Salvatore","year":"2014","journal-title":"J. Endometr."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0210","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3109\/13697137.2014.899347","article-title":"A 12-week treatment with fractional CO2 laser for vulvovaginal atrophy: a pilot study","volume":"17","author":"Salvatore","year":"2014","journal-title":"Climateric"},{"key":"10.1016\/j.maturitas.2015.08.001_bib0215","doi-asserted-by":"crossref","first-page":"219","DOI":"10.3109\/13697137.2014.975197","article-title":"Sexual function after fractional microablative CO2 laser in women with vulvovaginal atrophy","volume":"18","author":"Salvatore","year":"2015","journal-title":"Climacteric"},{"key":"10.1016\/j.maturitas.2015.08.001_bib0220","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.maturitas.2014.12.006","article-title":"Vulvo-vaginal atrophy: a new treatment modality using thermo-ablative fractional CO2 laser","volume":"80","author":"Perino","year":"2015","journal-title":"Maturitas"},{"key":"10.1016\/j.maturitas.2015.08.001_bib0225","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s10103-014-1677-2","article-title":"Microscopic and ultrastructural modifications of postmenopausal atrophic vaginal mucosa after fractional carbon dioxide laser treatment","volume":"30","author":"Zerbinati","year":"2015","journal-title":"Lasers Med. Sci."},{"issue":"12","key":"10.1016\/j.maturitas.2015.08.001_bib0230","doi-asserted-by":"crossref","DOI":"10.1089\/pho.2012.9881","article-title":"Regenerative medicine, stem cells, and low-level laser therapy: future directives","volume":"30","author":"Abrahamse","year":"2012","journal-title":"Photomed. Laser Surg."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0235","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1111\/j.1529-8019.2009.01265.x","article-title":"Fractional CO2 laser: novel therapeutic device upon photobiomodulation of tissue remodeling and cytokine pathway of tissue repair","volume":"22","author":"Prignano","year":"2009","journal-title":"Dermatol. Ther."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0240","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/j.1524-4725.2008.34413.x","article-title":"A prospective study of fractional scanned nonsequential carbon dioxide laser resurfacing: a clinical and histopathologic evaluation","volume":"35","author":"Berlin","year":"2009","journal-title":"Dermatol. Surg."},{"key":"10.1016\/j.maturitas.2015.08.001_bib0245","doi-asserted-by":"crossref","first-page":"129","DOI":"10.5978\/islsm.14-OR-11","article-title":"Treatment of vaginal relaxation syndrome with an Erbium: YAG laser using 90\u00b0 and 360\u00b0 scanning scopes: a pilot study & short-term results","volume":"23.2","author":"Lee","year":"2014","journal-title":"Laser Ther."},{"issue":"3","key":"10.1016\/j.maturitas.2015.08.001_bib0250","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1097\/gme.0b013e3181c1ac01","article-title":"Ospemifene effectively treats vulvovaginal atrophy in postmenopausal women: results from a pivotal phase 3 study","volume":"17","author":"Bachmann","year":"2010","journal-title":"Menopause: J. N. Am. Menopause Soc."}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512215300360?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512215300360?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T09:04:08Z","timestamp":1759914248000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512215300360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0378512215300360"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2015.08.001","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genitourinary syndrome of menopause and the use of laser therapy","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2015.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}