{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:56:07Z","timestamp":1787169367306,"version":"build-2736575974"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.maturitas.2019.04.203","type":"journal-article","created":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T21:54:21Z","timestamp":1554328461000},"page":"41-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":72,"special_numbering":"C","title":["Measuring testosterone in women and men"],"prefix":"10.1016","volume":"125","author":[{"given":"George A.","family":"Kanakis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos P.","family":"Tsametis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios G.","family":"Goulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.maturitas.2019.04.203_bib0005","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1210\/jc.2006-1864","article-title":"Position statement: utility, limitations, and pitfalls in measuring testosterone: an endocrine society position statement","volume":"92","author":"Rosner","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0010","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1210\/er.2001-0031","article-title":"Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone","volume":"24","author":"Labrie","year":"2003","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0015","series-title":"Williams Textb. Endocrinol","first-page":"709","author":"Matsumoto","year":"2011"},{"key":"10.1016\/j.maturitas.2019.04.203_bib0020","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jogc.2017.01.006","article-title":"Testosterone in women: measurement and therapeutic use","volume":"39","author":"Korkidakis","year":"2017","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2605.2008.00924.x","article-title":"Investigation, treatment and monitoring of late-onset hypogonadism in males","volume":"32","author":"Wang","year":"2009","journal-title":"Int. J. Androl."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1210\/jc.2018-00229","article-title":"Testosterone therapy in men with androgen deficiency syndromes: an endocrine society clinical practice guideline","volume":"103","author":"Bhasin","year":"2018","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0035","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1210\/jc.2016-2935","article-title":"Harmonized reference ranges for circulating testosterone levels in men of four cohort studies in the United States and Europe","volume":"102","author":"Travison","year":"2017","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0040","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/j.1939-4640.1989.tb00120.x","article-title":"Circadian variation in testosterone, sex hormone-binding globulin, and calculated non-sex hormone-binding globulin bound testosterone in healthy young and elderly men","volume":"10","author":"Plymate","year":"2019","journal-title":"J. Androl."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0045","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/j.1439-0272.2012.01296.x","article-title":"S-testosterone decrease after a mixed meal in healthy men independent of SHBG and gonadotrophin levels","volume":"44","author":"Lehtihet","year":"2012","journal-title":"Andrologia"},{"key":"10.1016\/j.maturitas.2019.04.203_bib0050","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1111\/j.1365-2265.2007.02976.x","article-title":"Intraindividual variation in levels of serum testosterone and other reproductive and adrenal hormones in men","volume":"67","author":"Brambilla","year":"2007","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"10.1016\/j.maturitas.2019.04.203_bib0055","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/ajhb.21045","article-title":"Toward quantifying the usage costs of human immunity: altered metabolic rates and hormone levels during acute immune activation in men","volume":"22","author":"Muehlenbein","year":"2019","journal-title":"Am. J. Hum. Biol."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0060","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1016\/j.fertnstert.2005.01.096","article-title":"Phenotypic spectrum of polycystic ovary syndrome: clinical and biochemical characterization of the three major clinical subgroups","volume":"83","author":"Chang","year":"2005","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0065","first-page":"0","article-title":"Large divergence in testosterone concentrations between men and women: frame of reference for elite athletes in sex-specific competition in sports, a narrative review","author":"Clark","year":"2018","journal-title":"Clin. Endocrinol. (Oxf.)"},{"key":"10.1016\/j.maturitas.2019.04.203_bib0070","doi-asserted-by":"crossref","DOI":"10.4103\/1008-682X.122338","article-title":"Challenges and improvements in testosterone and estradiol testing","author":"Vesper","year":"2014","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0075","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.jsbmb.2010.05.001","article-title":"Advantages and challenges of mass spectrometry assays for steroid hormones","volume":"121","author":"Stanczyk","year":"2010","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0080","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.steroids.2009.01.004","article-title":"Interlaboratory comparison study of serum total testosterone [corrected] measurements performed by mass spectrometry methods","volume":"74","author":"Vesper","year":"2009","journal-title":"Steroids"},{"key":"10.1016\/j.maturitas.2019.04.203_bib0085","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1373\/49.8.1381","article-title":"Testosterone measured by 10 immunoassays and by isotope-dilution gas chromatography-mass spectrometry in sera from 116 men, women, and children","volume":"49","author":"Taieb","year":"2003","journal-title":"Clin. Chem."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0090","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1530\/EJE-11-1051","article-title":"Comparison of serum testosterone and estradiol measurements in 3174 European men using platform immunoassay and mass spectrometry; relevance for the diagnostics in aging men","volume":"166","author":"Huhtaniemi","year":"2012","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0095","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.clinbiochem.2018.05.008","article-title":"How low can you go? Analytical performance of five automated testosterone immunoassays","volume":"58","author":"La\u2019ulu","year":"2018","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0100","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1373\/clinchem.2004.037358","article-title":"Evaluation of a candidate reference measurement procedure for serum free testosterone based on ultrafiltration and isotope dilution-gas chromatography-mass spectrometry","volume":"50","author":"Van Uytfanghe","year":"2004","journal-title":"Clin. Chem."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0105","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.fertnstert.2018.05.004","article-title":"Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome","volume":"110","author":"Teede","year":"2018","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0110","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1373\/clinchem.2005.063354","article-title":"Calculation of bioavailable and free testosterone in men: a comparison of 5 published algorithms","volume":"52","author":"de Ronde","year":"2006","journal-title":"Clin. Chem."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0115","first-page":"2380","article-title":"Commentary: androgen replacement therapy in the aging male - a critical evaluation","volume":"86","author":"Vermeulen","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0120","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0960-0760(93)90350-6","article-title":"The free androgen index is not valid for adult males","volume":"45","author":"Kapoor","year":"1993","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.maturitas.2019.04.203_bib0125","doi-asserted-by":"crossref","first-page":"4542","DOI":"10.1210\/jc.2010-1314","article-title":"Toward excellence in testosterone testing: a consensus statement","volume":"95","author":"Rosner","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512219300192?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512219300192?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T09:14:14Z","timestamp":1759914854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512219300192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":25,"alternative-id":["S0378512219300192"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2019.04.203","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Measuring testosterone in women and men","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2019.04.203","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}