{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T16:43:58Z","timestamp":1776962638258,"version":"3.51.4"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100012043","name":"Kindai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012043","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.maturitas.2019.10.010","type":"journal-article","created":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T11:39:57Z","timestamp":1572867597000},"page":"40-47","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Decreased bone mineral density and osteoporotic fractures are associated with the development of echogenic plaques in the carotid arteries over a 10-year follow-up period: The Japanese Population-based Osteoporosis (JPOS) Cohort Study"],"prefix":"10.1016","volume":"131","author":[{"given":"Masami","family":"Hamada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etsuko","family":"Kajita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Tamaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuyasu","family":"Kouda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuho","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Tachiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Yura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuniyasu","family":"Kamiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akemi","family":"Nitta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadanobu","family":"Kagamimori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Iki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.maturitas.2019.10.010_bib0005","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1359\/JBMR.050711","article-title":"Relationship between osteoporosis and cardiovascular disease in postmenopausal women","volume":"20","author":"Tanko","year":"2005","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0010","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.ijcard.2011.10.114","article-title":"Bone mineral density and all-cause, cardiovascular and stroke mortality: a meta-analysis of prospective cohort studies","volume":"166","author":"Qu","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0015","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1002\/jbmr.3089","article-title":"Relationship between low bone mineral density and fractures with incident cardiovascular disease: a systematic review and meta-analysis","volume":"32","author":"Veronese","year":"2017","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0020","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1210\/jcem-72-6-1372","article-title":"The influence of osteophytes and aortic calcification on spinal mineral density in postmenopausal women","volume":"72","author":"Reid","year":"1991","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0025","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1532-5415.1997.tb04498.x","article-title":"Bone mineral density and aortic calcification: the Study of Osteoporotic Fractures","volume":"45","author":"Vogt","year":"1997","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0030","doi-asserted-by":"crossref","first-page":"12","DOI":"10.23736\/S0026-4806.18.05632-X","article-title":"Relationship between carotid or coronary artery calcification and osteoporosis in the elderly","volume":"110","author":"Zhu","year":"2019","journal-title":"Minerva Med."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0035","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/aje\/kwh252","article-title":"Low bone mineral density is related to echogenic carotid artery plaques: a population-based study","volume":"160","author":"Jorgensen","year":"2004","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0040","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s00223-008-9141-6","article-title":"Echogenic carotid artery plaques are associated with vertebral fractures in postmenopausal women with low bone mass","volume":"82","author":"Kim","year":"2008","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0045","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00198-008-0633-z","article-title":"Low bone mass is associated with carotid atherosclerosis in postmenopausal women: the Japanese Population-based Osteoporosis (JPOS) Cohort Study","volume":"20","author":"Tamaki","year":"2009","journal-title":"Osteoporosis Int."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0050","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.maturitas.2018.11.001","article-title":"Low bone mineral density is associated with an elevated risk of developing increased arterial stiffness: a 10-year follow-up of Japanese women from the Japanese population-based Osteoporosis (JPOS) cohort study","volume":"119","author":"Jaalkhorol","year":"2019","journal-title":"Maturitas"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0055","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s00223-006-0071-x","article-title":"Carotid plaque echogenicity and risk of nonvertebral fractures in women: a longitudinal population-based study","volume":"79","author":"Jorgensen","year":"2006","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0060","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1161\/01.ATV.19.1.2","article-title":"Ultrasound and lipoproteins as predictors of lipid-rich, rupture-prone plaques in the carotid artery","volume":"19","author":"Gronholdt","year":"1999","journal-title":"Arteriosclerosis Thrombosis Vasc. Biol."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0065","doi-asserted-by":"crossref","first-page":"2189","DOI":"10.1161\/01.STR.31.9.2189","article-title":"Reproducibility of computer-quantified carotid plaque echogenicity: can we overcome the subjectivity?","volume":"31","author":"Sabetai","year":"2000","journal-title":"Stroke"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0070","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.gheart.2016.08.006","article-title":"Carotid intima-media thickness as surrogate for and predictor of CVD","volume":"11","author":"Polak","year":"2016","journal-title":"Glob. Heart"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0075","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1161\/01.STR.32.5.1120","article-title":"Acoustic shadowing on B-mode ultrasound of the carotid artery predicts ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study","volume":"32","author":"Hunt","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0080","first-page":"819","article-title":"Prognostic implications of sonographic characteristics of carotid plaques in patients with acute coronary syndromes","volume":"91","author":"Komorovsky","year":"2005","journal-title":"Heart (British Cardiac Society)"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0085","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCIMAGING.114.002262","article-title":"Comparison of coronary artery calcium presence, carotid plaque presence, and carotid intima-media thickness for cardiovascular disease prediction in the Multi-Ethnic Study of Atherosclerosis","volume":"8","author":"Gepner","year":"2015","journal-title":"Circ. Cardiovasc. Imaging"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0090","first-page":"50","article-title":"The Joint Committee of \"The Japan Academy of Neurosonology\" and \"The Japan Society of Embolus Detection and Treatment\" on Guideline for Nuerosonology, Carotid Ultrasound Examination","volume":"19","year":"2006","journal-title":"Neurosonology"},{"issue":"11","key":"10.1016\/j.maturitas.2019.10.010_bib0095","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1161\/01.STR.28.11.2201","article-title":"Reproducibility of ultrasound assessment of carotid plaque occurrence, thickness, and morphology. The Tromso Study","volume":"28","author":"Joakimsen","year":"1997","journal-title":"Stroke"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0100","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jocd.2006.05.003","article-title":"Skeletal sites for osteoporosis diagnosis: the 2005 ISCD Official Positions","volume":"9","author":"Hans","year":"2006","journal-title":"J. Clin. Densitom."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0105","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/jbmr.2048","article-title":"Trabecular bone score (TBS) predicts vertebral fractures in Japanese women over 10 years independently of bone density and prevalent vertebral deformity: the Japanese Population-Based Osteoporosis (JPOS) cohort study","volume":"29","author":"Iki","year":"2014","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0110","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/BF01623275","article-title":"The assessment of vertebral deformity: a method for use in population studies and clinical trials","volume":"3","author":"McCloskey","year":"1993","journal-title":"Osteoporosis Int."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0115","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","article-title":"Vertebral fracture assessment using a semiquantitative technique","volume":"8","author":"Genant","year":"1993","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0120","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s001980050288","article-title":"Validity of self-report of fractures: results from a prospective study in men and women across Europe. EPOS Study Group. European Prospective Osteoporosis Study Group","volume":"11","author":"Ismail","year":"2000","journal-title":"Osteoporosis Int."},{"issue":"9","key":"10.1016\/j.maturitas.2019.10.010_bib0125","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1002\/jbmr.1652","article-title":"Differing risk profiles for individual fracture sites: evidence from the Global Longitudinal Study of Osteoporosis in Women (GLOW)","volume":"27","author":"FitzGerald","year":"2012","journal-title":"J. Bone Miner. Res."},{"issue":"2","key":"10.1016\/j.maturitas.2019.10.010_bib0130","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1177\/1094428104263672","article-title":"Using generalized estimating equations for longitudinal data analysis","volume":"7","author":"Ballinger","year":"2004","journal-title":"Organ. Res. Methods"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0135","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s00774-017-0849-0","article-title":"Abdominal aortic calcification and the risk of bone fractures: a meta-analysis of prospective cohort studies","volume":"36","author":"Wei","year":"2018","journal-title":"J. Bone Miner. Metab."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0140","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1161\/01.CIR.0000120708.59903.1B","article-title":"Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction: the Rotterdam Study","volume":"109","author":"van der Meer","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.maturitas.2019.10.010_bib0145","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.ahj.2004.07.019","article-title":"Risk factors for cardiovascular event recurrence in the Atherosclerosis Risk in Communities (ARIC) study","volume":"149","author":"Wattanakit","year":"2005","journal-title":"Am. Heart J."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0150","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s00198-007-0540-8","article-title":"Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy","volume":"19","author":"Russell","year":"2008","journal-title":"Osteoporosis Int."},{"key":"10.1016\/j.maturitas.2019.10.010_bib0155","doi-asserted-by":"crossref","first-page":"403","DOI":"10.2165\/00003088-199732050-00005","article-title":"Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences","volume":"32","author":"Lennernas","year":"1997","journal-title":"Clin. Pharmacokinet."}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037851221930653X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037851221930653X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T09:15:22Z","timestamp":1759914922000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S037851221930653X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":31,"alternative-id":["S037851221930653X"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2019.10.010","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Decreased bone mineral density and osteoporotic fractures are associated with the development of echogenic plaques in the carotid arteries over a 10-year follow-up period: The Japanese Population-based Osteoporosis (JPOS) Cohort Study","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2019.10.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}