{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:24:34Z","timestamp":1784042674482,"version":"3.55.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.maturitas.2020.12.004","type":"journal-article","created":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T16:49:36Z","timestamp":1608828576000},"page":"6-11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Depression and the Risk of Fractures in Later Life: the Health In Men Cohort Study"],"prefix":"10.1016","volume":"145","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8689-6199","authenticated-orcid":false,"given":"Osvaldo P.","family":"Almeida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme J.","family":"Hankey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Golledge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bu B.","family":"Yeap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon","family":"Flicker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.maturitas.2020.12.004_bib0005","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/S0140-6736(16)31460-X","article-title":"Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015","volume":"388","author":"Global Burden of Disease Study Collaborators","year":"2016","journal-title":"Lancet"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0010","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1001\/archinte.160.12.1818","article-title":"Patients with depression are less likely to follow recommendations to reduce cardiac risk during recovery from a myocardial infarction","volume":"160","author":"Ziegelstein","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0015","doi-asserted-by":"crossref","first-page":"e2423","DOI":"10.1371\/journal.pone.0002423","article-title":"Falls, depression and antidepressants in later life: a large primary care appraisal","volume":"3","author":"Kerse","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0020","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1007\/s00198-018-4420-1","article-title":"Depression and risk of fracture and bone loss: an updated meta-analysis of prospective studies","volume":"29","author":"Wu","year":"2018","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0025","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s00198-011-1778-8","article-title":"Selective serotonin reuptake inhibitor treatment and risk of fractures: a meta-analysis of cohort and case-control studies","volume":"23","author":"Wu","year":"2012","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0030","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S1474-4422(20)30207-6","article-title":"Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial","volume":"19","author":"Affinity Trial Collaboration","year":"2020","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0035","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jad.2005.02.014","article-title":"Depression and smoking amongst older general practice patients","volume":"86","author":"Almeida","year":"2005","journal-title":"J Affect Disord"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0040","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1136\/bjsports-2013-092814","article-title":"150 minutes of vigorous physical activity per week predicts survival and successful ageing: a population-based 11-year longitudinal study of 12 201 older Australian men","volume":"48","author":"Almeida","year":"2014","journal-title":"British journal of sports medicine"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0045","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1017\/S1041610210001870","article-title":"A practical approach to assess depression risk and to guide risk reduction strategies in later life","volume":"23","author":"Almeida","year":"2011","journal-title":"Int Psychogeriatr"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0050","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1001\/archinte.161.7.983","article-title":"Cigarette smoking, alcohol consumption, and risk of hip fracture in women","volume":"161","author":"Baron","year":"2001","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0055","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1001\/archinte.160.5.705","article-title":"Physical activity and osteoporotic hip fracture risk in men","volume":"160","author":"Kujala","year":"2000","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0060","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1001\/archgenpsychiatry.2007.33","article-title":"Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men","volume":"65","author":"Almeida","year":"2008","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0065","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1192\/bjp.bp.111.106666","article-title":"Vitamin D deficiency and depression in adults: systematic review and meta-analysis","volume":"202","author":"Anglin","year":"2013","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0070","doi-asserted-by":"crossref","DOI":"10.1210\/clinem\/dgaa115","article-title":"U-Shaped Association of Plasma Testosterone, and no Association of Plasma Estradiol, with Incidence of Fractures in Men","volume":"105","author":"Yeap","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0075","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s00198-015-3386-5","article-title":"Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation","volume":"27","author":"Weaver","year":"2016","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0080","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1056\/NEJMoa032546","article-title":"Homocysteine levels and the risk of osteoporotic fracture","volume":"350","author":"van Meurs","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0085","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0174730","article-title":"Benzodiazepines, Z-drugs and the risk of hip fracture: A systematic review and meta-analysis","volume":"12","author":"Donnelly","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0090","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1093\/ije\/dyn041","article-title":"Cohort Profile: The Health In Men Study (HIMS)","volume":"38","author":"Norman","year":"2009","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0111882","article-title":"Mortality among People with Severe Mental Disorders Who Reach Old Age: A Longitudinal Study of a Community-Representative Sample of 37892 Men","volume":"9","author":"Almeida","year":"2014","journal-title":"PLoS One"},{"issue":"439","key":"10.1016\/j.maturitas.2020.12.004_bib0100","first-page":"e431","article-title":"How many older people are frail? Using multiple imputation to investigate frailty in the population","volume":"16","author":"McCaul","year":"2015","journal-title":"J Am Med Dir Assoc"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0105","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1467-842X.1999.tb01297.x","article-title":"Population-based linkage of health records in Western Australia: development of a health services research linked database","volume":"23","author":"Holman","year":"1999","journal-title":"Aust N Z J Public Health"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0110","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1071\/AH080766","article-title":"A decade of data linkage in Western Australia: strategic design, applications and benefits of the WA data linkage system","volume":"32","author":"Holman","year":"2008","journal-title":"Aust Health Rev"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0115","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/(SICI)1099-1166(199910)14:10<858::AID-GPS35>3.0.CO;2-8","article-title":"Short versions of the geriatric depression scale: a study of their validity for the diagnosis of a major depressive episode according to ICD-10 and DSM-IV","volume":"14","author":"Almeida","year":"1999","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0120","doi-asserted-by":"crossref","first-page":"3165","DOI":"10.1210\/jc.2009-2754","article-title":"Low free testosterone predicts frailty in older men: the health in men study","volume":"95","author":"Hyde","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0125","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1093\/ije\/dyp199","article-title":"Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study","volume":"38","author":"Almeida","year":"2009","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0130","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.maturitas.2015.01.016","article-title":"Vitamin D concentration and its association with past, current and future depression in older men: The Health In Men Study","volume":"81","author":"Almeida","year":"2015","journal-title":"Maturitas"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0135","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1001\/archpsyc.65.11.1286","article-title":"Homocysteine and depression in later life","volume":"65","author":"Almeida","year":"2008","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0140","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.psyneuen.2015.11.012","article-title":"Prospective longitudinal study of testosterone and incident depression in older men: The Health In Men Study","volume":"64","author":"Ford","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0145","doi-asserted-by":"crossref","first-page":"268","DOI":"10.7326\/M16-2607","article-title":"Sensitivity Analysis in Observational Research: Introducing the E-Value","volume":"167","author":"VanderWeele","year":"2017","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0150","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1002\/cncr.29924","article-title":"A. note on the magnitude of hazard ratios","volume":"122","author":"Azuero","year":"2016","journal-title":"Cancer"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0155","series-title":"3412.0 - Migration, Australia, 2013-2014","author":"ABS","year":"2015"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0160","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1001\/archinte.167.21.2329","article-title":"Low bone mass in premenopausal women with depression","volume":"167","author":"Eskandari","year":"2007","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0165","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s40266-015-0323-4","article-title":"Effects of Depression and Serotonergic Antidepressants on Bone: Mechanisms and Implications for the Treatment of Depression","volume":"33","author":"Fernandes","year":"2016","journal-title":"Drugs Aging"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0170","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0140-6736(18)32823-X","article-title":"Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial","volume":"393","author":"Focus Trial Collaboration","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.maturitas.2020.12.004_bib0175","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1001\/jamapsychiatry.2018.3679","article-title":"Association Between Antidepressant Drug Use and Hip Fracture in Older People Before and After Treatment Initiation","volume":"76","author":"Brannstrom","year":"2019","journal-title":"JAMA Psychiatry"}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512220304515?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512220304515?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T09:16:52Z","timestamp":1759915012000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512220304515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":35,"alternative-id":["S0378512220304515"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2020.12.004","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Depression and the Risk of Fractures in Later Life: the Health In Men Cohort Study","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2020.12.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}