{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:43:08Z","timestamp":1790602988514,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["26242059"],"award-info":[{"award-number":["26242059"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K19950"],"award-info":[{"award-number":["23K19950"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007312","name":"National Center for Geriatrics and Gerontology","doi-asserted-by":"publisher","award":["27-22"],"award-info":[{"award-number":["27-22"]}],"id":[{"id":"10.13039\/501100007312","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["15dk0107003h0003"],"award-info":[{"award-number":["15dk0107003h0003"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["15dk0207004h0203"],"award-info":[{"award-number":["15dk0207004h0203"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.maturitas.2025.108597","type":"journal-article","created":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T06:32:51Z","timestamp":1746858771000},"page":"108597","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Cognitive activity levels associated with dementia risk in older adults with social frailty: A longitudinal study"],"prefix":"10.1016","volume":"198","author":[{"given":"Fumio","family":"Sakimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takehiko","family":"Doi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouki","family":"Tomida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soichiro","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keitaro","family":"Makino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.maturitas.2025.108597_bb0005","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1007\/s10433-017-0414-7","article-title":"Social frailty in older adults: a scoping review","volume":"14","author":"Bunt","year":"2017","journal-title":"Eur. J. Ageing"},{"key":"10.1016\/j.maturitas.2025.108597_bb0010","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.archger.2018.06.005","article-title":"Assessing the social dimension of frailty in old age: a systematic review","volume":"78","author":"Bessa","year":"2018","journal-title":"Arch. Gerontol. Geriatr."},{"issue":"9","key":"10.1016\/j.maturitas.2025.108597_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.jamda.2024.105124","article-title":"Longitudinal relationship between baseline social frailty and cognitive impairment in older adults: 14-year follow-up results from the Korean Longitudinal Study of Ageing","volume":"25","author":"Lee","year":"2024","journal-title":"J. Am. Med. Dir. Assoc."},{"issue":"2","key":"10.1016\/j.maturitas.2025.108597_bb0020","doi-asserted-by":"crossref","first-page":"587","DOI":"10.3233\/JAD-181178","article-title":"Impact of social frailty on Alzheimer\u2019s disease onset: a 53-month longitudinal cohort study","volume":"70","author":"Tsutsumimoto","year":"2019","journal-title":"J. Alzheimers Dis."},{"issue":"1","key":"10.1016\/j.maturitas.2025.108597_bb0025","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1038\/s41598-024-53984-3","article-title":"Social frailty as a predictor of all-cause mortality and functional disability: a systematic review and meta-analysis","volume":"14","author":"Goto","year":"2024","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.maturitas.2025.108597_bb0030","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1093\/ageing\/afs047","article-title":"Prevalence of frailty phenotypes and risk of mortality in a community-dwelling elderly cohort","volume":"42","author":"Garre-Olmo","year":"2013","journal-title":"Age Ageing"},{"issue":"3","key":"10.1016\/j.maturitas.2025.108597_bb0035","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/jgs.18140","article-title":"Social isolation and 9-year dementia risk in community-dwelling Medicare beneficiaries in the United States","volume":"71","author":"Huang","year":"2023","journal-title":"J. Am. Geriatr. Soc."},{"issue":"9","key":"10.1016\/j.maturitas.2025.108597_bb0040","doi-asserted-by":"crossref","first-page":"5397","DOI":"10.1111\/ejn.15373","article-title":"Potential neurobiological links between social isolation and Alzheimer's disease risk","volume":"56","author":"Drinkwater","year":"2022","journal-title":"Eur. J. Neurosci."},{"issue":"1","key":"10.1016\/j.maturitas.2025.108597_bb0045","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jamda.2022.10.007","article-title":"The prevalence of social frailty among older adults: a systematic review and meta-analysis","volume":"24","author":"Zhang","year":"2023","journal-title":"J. Am. Med. Dir. Assoc."},{"issue":"4","key":"10.1016\/j.maturitas.2025.108597_bb0050","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/ppar\/prx030","article-title":"The potential public health relevance of social isolation and loneliness: prevalence, epidemiology, and risk factors","volume":"27","author":"Holt-Lunstad","year":"2017","journal-title":"Public Policy & Aging Report"},{"issue":"12","key":"10.1016\/j.maturitas.2025.108597_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph17124239","article-title":"Social frailty is independently associated with mood, nutrition, physical performance, and physical activity: insights from a theory-guided approach","volume":"17","author":"Pek","year":"2020","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.maturitas.2025.108597_bb0060","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.maturitas.2021.06.015","article-title":"Effect of social participation on the development of physical frailty: do type, frequency and diversity matter?","volume":"151","author":"Xie","year":"2021","journal-title":"Maturitas"},{"issue":"1","key":"10.1016\/j.maturitas.2025.108597_bb0065","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s11205-012-0097-6","article-title":"Ageing, leisure, and social connectedness: how could leisure help reduce social isolation of older people?","volume":"113","author":"Toepoel","year":"2013","journal-title":"Soc. Indic. Res."},{"issue":"3","key":"10.1016\/j.maturitas.2025.108597_bb0070","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.eurger.2013.09.003","article-title":"Leisure time activities and cognitive functioning in middle European population-based study","volume":"5","author":"Blasko","year":"2014","journal-title":"European Geriatric Medicine"},{"issue":"7","key":"10.1016\/j.maturitas.2025.108597_bb0075","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1001\/jamapsychiatry.2018.0657","article-title":"Association of daily intellectual activities with lower risk of incident dementia among older Chinese adults","volume":"75","author":"Lee","year":"2018","journal-title":"JAMA Psychiatry"},{"issue":"7","key":"10.1016\/j.maturitas.2025.108597_bb0080","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0158720","article-title":"Cognitive impairment and disability in older Japanese adults","volume":"11","author":"Shimada","year":"2016","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.maturitas.2025.108597_bb0085","doi-asserted-by":"crossref","first-page":"659","DOI":"10.3233\/JAD-231420","article-title":"Elevated risk of dementia diagnosis in older adults with low frequencies and durations of social conversation","volume":"98","author":"Shimada","year":"2024","journal-title":"J. Alzheimers Dis."},{"issue":"3","key":"10.1016\/j.maturitas.2025.108597_bb0090","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/j.1532-5415.2005.53175.x","article-title":"Care-needs certification in the long-term care insurance system of Japan","volume":"53","author":"Tsutsui","year":"2005","journal-title":"J. Am. Geriatr. Soc."},{"issue":"11","key":"10.1016\/j.maturitas.2025.108597_bb0095","doi-asserted-by":"crossref","first-page":"1003.e7","DOI":"10.1016\/j.jamda.2015.08.023","article-title":"Social frailty in community-dwelling older adults as a risk factor for disability","volume":"16","author":"Makizako","year":"2015","journal-title":"J. Am. Med. Dir. Assoc."},{"issue":"4","key":"10.1016\/j.maturitas.2025.108597_bb0100","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.jamda.2024.02.002","article-title":"Impacts of negative and positive life events on development of social frailty among community-dwelling older adults","volume":"25","author":"Makino","year":"2024","journal-title":"J. Am. Med. Dir. Assoc."},{"issue":"5","key":"10.1016\/j.maturitas.2025.108597_bb0105","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9051424","article-title":"Engagement in lifestyle activities is associated with increased Alzheimer\u2019s disease-associated cortical thickness and cognitive performance in older adults","volume":"9","author":"Bae","year":"2020","journal-title":"J. Clin. Med."},{"issue":"7","key":"10.1016\/j.maturitas.2025.108597_bb0110","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.23690","article-title":"Lifestyle enrichment in later life and its association with dementia risk","volume":"6","author":"Wu","year":"2023","journal-title":"JAMA Netw. Open"},{"issue":"1","key":"10.1016\/j.maturitas.2025.108597_bb0115","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/gps.2490","article-title":"Baseline leisure time activity and cognition more than two decades later","volume":"26","author":"K\u00e5reholt","year":"2011","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"8","key":"10.1016\/j.maturitas.2025.108597_bb0120","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1093\/gerona\/63.8.848","article-title":"White matter lesions and cognitive performance: the role of cognitively complex leisure activity","volume":"63","author":"Saczynski","year":"2008","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"issue":"25","key":"10.1016\/j.maturitas.2025.108597_bb0125","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1056\/NEJMoa022252","article-title":"Leisure activities and the risk of dementia in the elderly","volume":"348","author":"Verghese","year":"2003","journal-title":"N. Engl. J. Med."},{"issue":"15","key":"10.1016\/j.maturitas.2025.108597_bb0130","doi-asserted-by":"crossref","first-page":"e1651","DOI":"10.1212\/WNL.0000000000200929","article-title":"Leisure activities and the risk of dementia: a systematic review and meta-analysis","volume":"99","author":"Su","year":"2022","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.maturitas.2025.108597_bb0135","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1152\/physrev.00004.2002","article-title":"Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior","volume":"82","author":"Mattson","year":"2002","journal-title":"Physiol. Rev."},{"issue":"8","key":"10.1016\/j.maturitas.2025.108597_bb0140","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.neurobiolaging.2014.02.015","article-title":"Neuroprotective pathways: lifestyle activity, brain pathology, and cognition in cognitively normal older adults","volume":"35","author":"Wirth","year":"2014","journal-title":"Neurobiol. Aging"},{"issue":"4","key":"10.1016\/j.maturitas.2025.108597_bb0145","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1212\/WNL.0b013e31829c5e8a","article-title":"Life-span cognitive activity, neuropathologic burden, and cognitive aging","volume":"81","author":"Wilson","year":"2013","journal-title":"Neurology"},{"issue":"5","key":"10.1016\/j.maturitas.2025.108597_bb0150","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s11910-009-0053-2","article-title":"Immunologically mediated dementias","volume":"9","author":"Rosenbloom","year":"2009","journal-title":"Curr. Neurol. Neurosci. Rep."}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512225004050?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512225004050?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,15]],"date-time":"2025-06-15T18:38:33Z","timestamp":1750012713000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512225004050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":30,"alternative-id":["S0378512225004050"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2025.108597","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cognitive activity levels associated with dementia risk in older adults with social frailty: A longitudinal study","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2025.108597","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108597"}}