{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:45:08Z","timestamp":1792604708105,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["NMRC\/OFLCG\/MOH-001327-03"],"award-info":[{"award-number":["NMRC\/OFLCG\/MOH-001327-03"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","award":["NMRC\/HCSAINV\/MOH-001019-00"],"award-info":[{"award-number":["NMRC\/HCSAINV\/MOH-001019-00"]}],"id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.maturitas.2025.108599","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T14:00:36Z","timestamp":1748872836000},"page":"108599","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Probability of progression and regression of chronic kidney disease in patients with type 2 diabetes mellitus"],"prefix":"10.1016","volume":"198","author":[{"given":"Barry Moses Quan Ren","family":"Koh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin Siew Wei","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia Ciwei","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kavita","family":"Venkataraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charumathi","family":"Sabanayagam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.maturitas.2025.108599_bb0005","first-page":"2918","article-title":"Cardiovascular disease and its relationship with chronic kidney disease","volume":"18","author":"Liu","year":"2014","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.maturitas.2025.108599_bb0010","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","article-title":"Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"395","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.maturitas.2025.108599_bb0015","doi-asserted-by":"crossref","first-page":"A7","DOI":"10.1053\/j.ajkd.2019.01.001","article-title":"US renal data system 2018 annual data report: epidemiology of kidney disease in the United States","volume":"73","author":"Saran","year":"2019","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.maturitas.2025.108599_bb0020","first-page":"1","article-title":"Annual all-cause mortality rate for patients with diabetic kidney disease in Singapore","volume":"4","author":"Ang","year":"2016","journal-title":"J. Clin. Transl. Endocrinol."},{"key":"10.1016\/j.maturitas.2025.108599_bb0025","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8866446","article-title":"Chronic kidney disease progression and transition probabilities in a large preventive cohort in Colombia","volume":"2021","author":"Vesga","year":"2021","journal-title":"Int J Nephrol"},{"key":"10.1016\/j.maturitas.2025.108599_bb0030","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.122.026685","article-title":"Progression of chronic kidney disease risk categories and risk of cardiovascular disease and total mortality: coronary artery risk development in young adults cohort","volume":"11","author":"Choi","year":"2022","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.maturitas.2025.108599_bb0035","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/ckj\/sfx083","article-title":"Patterns of progression of chronic kidney disease at later stages","volume":"11","author":"Caravaca-Font\u00e1n","year":"2018","journal-title":"Clin. Kidney J."},{"key":"10.1016\/j.maturitas.2025.108599_bb0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v038.i08","article-title":"Multi-state models for panel data: the msm package for R","volume":"38","author":"Jackson","year":"2011","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.maturitas.2025.108599_bb0045","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1177\/0962280209105541","article-title":"Model diagnostics for multi-state models","volume":"19","author":"Titman","year":"2010","journal-title":"Stat. Methods Med. Res."},{"key":"10.1016\/j.maturitas.2025.108599_bb0050","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1046\/j.1523-1755.2003.00712.x","article-title":"Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64)","volume":"63","author":"Adler","year":"2003","journal-title":"Kidney Int."},{"key":"10.1016\/j.maturitas.2025.108599_bb0055","first-page":"14","article-title":"A multi-state markov model for the progression of chronic kidney disease","volume":"11","author":"Grover","year":"2018","journal-title":"Turkiye Klinikleri journal of Biostatistics"},{"key":"10.1016\/j.maturitas.2025.108599_bb0060","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1177\/0272989X12466731","article-title":"Identification of a multistate continuous-time nonhomogeneous Markov chain model for patients with decreased renal function","volume":"33","author":"Begun","year":"2013","journal-title":"Med. Decis. Mak."},{"key":"10.1016\/j.maturitas.2025.108599_bb0065","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1053\/j.ajkd.2016.07.030","article-title":"A dynamic predictive model for progression of CKD","volume":"69","author":"Tangri","year":"2017","journal-title":"Am. J. Kidney Dis."},{"issue":"12","key":"10.1016\/j.maturitas.2025.108599_bb0070","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1016\/j.ophtha.2016.08.021","article-title":"Cost-effectiveness of a national telemedicine diabetic retinopathy screening program in Singapore","volume":"123","author":"Nguyen","year":"2016","journal-title":"Ophthalmology"},{"issue":"9","key":"10.1016\/j.maturitas.2025.108599_bb0075","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.maturitas.2025.108599_bb0080","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2020-001413","article-title":"Impact of type 2 diabetes and microvascular complications on mortality and cardiovascular outcomes in a multiethnic Asian population","volume":"9","author":"Yap","year":"2021","journal-title":"BMJ Open Diabetes Res. Care"},{"key":"10.1016\/j.maturitas.2025.108599_bb0085","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1053\/j.ajkd.2015.10.011","article-title":"Renin-angiotensin system inhibitors and kidney and cardiovascular outcomes in patients with CKD: a Bayesian network meta-analysis of randomized clinical trials","volume":"67","author":"Xie","year":"2016","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.maturitas.2025.108599_bb0090","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.25821","article-title":"Association of albuminuria and regression of chronic kidney disease in adults with newly diagnosed moderate to severe chronic kidney disease","volume":"5","author":"Pasternak","year":"2022","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.maturitas.2025.108599_bb0095","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1477-7525-10-71","article-title":"Health-related quality of life in different stages of chronic kidney disease and at initiation of dialysis treatment","volume":"10","author":"Pagels","year":"2012","journal-title":"Health Qual. Life Outcomes"},{"issue":"2022","key":"10.1016\/j.maturitas.2025.108599_bb0100","article-title":"Optimism and hope in chronic disease: a systematic review","volume":"7","author":"Schiavon","year":"2016","journal-title":"Front. Psychol."},{"key":"10.1016\/j.maturitas.2025.108599_bb0105","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.psym.2012.04.004","article-title":"Positive psychological attributes and cardiac outcomes: associations, mechanisms, and interventions","volume":"53","author":"Dubois","year":"2012","journal-title":"Psychosomatics"},{"key":"10.1016\/j.maturitas.2025.108599_bb0110","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.12828","article-title":"Progression and regression of chronic kidney disease by age among adults in a population-based cohort in Alberta, Canada","volume":"4","author":"Liu","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.maturitas.2025.108599_bb0115","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/nrneph.2016.163","article-title":"The global burden of chronic kidney disease: estimates, variability and pitfalls","volume":"13","author":"Glassock","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.maturitas.2025.108599_bb0120","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.cell.2014.10.039","article-title":"Geroscience: linking aging to chronic disease","volume":"159","author":"Kennedy","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.maturitas.2025.108599_bb0125","article-title":"Diabetic retinopathy is a prognostic factor for progression of chronic kidney disease in the patients with type 2 diabetes mellitus","volume":"14","author":"Park","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.maturitas.2025.108599_bb0130","first-page":"992","article-title":"Relationship between pigment epithelium-derived factor (PEDF) and renal function in patients with diabetic retinopathy","volume":"14","author":"Matsuyama","year":"2008","journal-title":"Mol. Vis."},{"key":"10.1016\/j.maturitas.2025.108599_bb0135","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1681\/ASN.V112319","article-title":"Effect of gender on the progression of nondiabetic renal disease: a meta-analysis","volume":"11","author":"Neugarten","year":"2000","journal-title":"J. Am. Soc. Nephrol."}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512225004074?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512225004074?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,15]],"date-time":"2025-06-15T18:38:33Z","timestamp":1750012713000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512225004074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":27,"alternative-id":["S0378512225004074"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2025.108599","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Probability of progression and regression of chronic kidney disease in patients with type 2 diabetes mellitus","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2025.108599","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108599"}}