{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:00:28Z","timestamp":1792177228529,"version":"4.4.0"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009459","name":"Copenhagen University Hospital Hvidovre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009459","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","maturitas.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Maturitas"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.maturitas.2025.108658","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T17:16:14Z","timestamp":1751562974000},"page":"108658","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Vaginal CO2 laser treatment for urinary stress incontinence: A randomized controlled trial"],"prefix":"10.1016","volume":"199","author":[{"given":"Hrefna B\u00f3el","family":"Sigurdard\u00f3ttir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benny","family":"Kirschner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josephine","family":"Obel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mubeena","family":"Aziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathrine Blegvad","family":"Stenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeppe Bennekou","family":"Schroll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.maturitas.2025.108658_bb0005","article-title":"Mid-urethral sling operations for stress urinary incontinence in women","volume":"2017","author":"Ford","year":"2017","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.maturitas.2025.108658_bb0010","first-page":"CD009508","article-title":"Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women","author":"Hay-Smith","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.maturitas.2025.108658_bb0015","first-page":"CD005654","article-title":"Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women","author":"Dumoulin","year":"2014","journal-title":"Cochrane Database Syst. Rev."},{"issue":"71","key":"10.1016\/j.maturitas.2025.108658_bb0020","first-page":"e1","article-title":"Sling surgery for stress urinary incontinence in women: a systematic review and metaanalysis","volume":"211","author":"Schimpf","year":"2014","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.maturitas.2025.108658_bb0025","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(16)32572-7","article-title":"Adverse events after first, single, mesh and non-mesh surgical procedures for stress urinary incontinence and pelvic organ prolapse in Scotland, 1997-2016: a population-based cohort study","volume":"389","author":"Morling","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.maturitas.2025.108658_bb0030","unstructured":"J. Wise, Surgical mesh for stress urinary incontinence to be halted immediately in England, (n.d.). doi: https:\/\/doi.org\/10.2307\/26960949."},{"key":"10.1016\/j.maturitas.2025.108658_bb0035","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s10103-014-1677-2","article-title":"Microscopic and ultrastructural modifications of postmenopausal atrophic vaginal mucosa after fractional carbon dioxide laser treatment","volume":"30","author":"Zerbinati","year":"2015","journal-title":"Lasers Med. Sci."},{"key":"10.1016\/j.maturitas.2025.108658_bb0040","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/lsm.22637","article-title":"Light and energy based therapeutics for genitourinary syndrome of menopause: consensus and controversies","volume":"49","author":"Tadir","year":"2017","journal-title":"Lasers Surg. Med."},{"key":"10.1016\/j.maturitas.2025.108658_bb0045","unstructured":"FDA, Statement from FDA Commissioner, (n.d.). https:\/\/www.fda.gov\/news-events\/press-announcements\/statement-fda-commissioner-scott-gottlieb-md-efforts-safeguard-womens-health-deceptive-health-claims."},{"key":"10.1016\/j.maturitas.2025.108658_bb0050","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1002\/lsm.23220","article-title":"Efficacy of fractional CO(2) laser, Promestriene, and vaginal lubricant in the treatment of urinary symptoms in postmenopausal women: a randomized clinical trial","volume":"52","author":"Aguiar","year":"2020","journal-title":"Lasers Surg. Med."},{"key":"10.1016\/j.maturitas.2025.108658_bb0055","doi-asserted-by":"crossref","DOI":"10.1007\/s00192-022-05103-x","article-title":"The efficacy and safety of a single maintenance laser treatment for stress urinary incontinence: a double-blinded randomized controlled trial","author":"Lauterbach","year":"2022","journal-title":"Int. Urogynecol. J."},{"key":"10.1016\/j.maturitas.2025.108658_bb0060","series-title":"CO2 Surgical Laser for Treatment of Stress Urinary Incontinence in Women: A Randomized Controlled Trial","first-page":"473.e1","author":"Alexander","year":"2022"},{"key":"10.1016\/j.maturitas.2025.108658_bb0065","doi-asserted-by":"crossref","DOI":"10.1007\/s00192-022-05091-y","article-title":"CO2 laser and radiofrequency compared to a sham control group in treatment of stress urinary incontinence (LARF study arm 3). A randomized controlled trial","author":"Seki","year":"2022","journal-title":"Int. Urogynecol. J."},{"key":"10.1016\/j.maturitas.2025.108658_bb0070","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1007\/s00192-023-05655-6","article-title":"Fractional CO2 laser treatment for women with stress predominant urinary incontinence: a randomized controlled trial","volume":"34","author":"Temtanakitpaisan","year":"2023","journal-title":"Int. Urogynecol. J."},{"key":"10.1016\/j.maturitas.2025.108658_bb0075","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.ejogrb.2018.03.038","article-title":"Non-ablative Er:YAG laser therapy effect on stress urinary incontinence related to quality of life and sexual function: a randomized controlled trial","volume":"224","author":"Blaganje","year":"2018","journal-title":"European Journal of Obstetrics and Gynecology and Reproductive Biology"},{"key":"10.1016\/j.maturitas.2025.108658_bb0080","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1002\/ijgo.15222","article-title":"Vaginal erbium laser treatment for stress urinary incontinence: a multicenter randomized sham-controlled clinical trial","volume":"164","author":"O\u2019Reilly","year":"2024","journal-title":"Int. J. Gynecol. Obstet."},{"key":"10.1016\/j.maturitas.2025.108658_bb0085","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/nau.20674","article-title":"Comparison of two questionnaires for assessing the severity of urinary incontinence: the ICIQ-UI SF versus the incontinence severity index","volume":"28","author":"Klovning","year":"2009","journal-title":"Neurourol.Urodyn."},{"key":"10.1016\/j.maturitas.2025.108658_bb0090","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0002-9378(96)70243-0","article-title":"The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction","volume":"175","author":"Bump","year":"1996","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.maturitas.2025.108658_bb0095","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3109\/13697137.2014.899347","article-title":"A 12-week treatment with fractional CO2 laser for vulvovaginal atrophy: a pilot study","volume":"17","author":"Salvatore","year":"2014","journal-title":"Climacteric"},{"key":"10.1016\/j.maturitas.2025.108658_bb0100","author":"Sample size calculator"},{"key":"10.1016\/j.maturitas.2025.108658_bb0105","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.urology.2019.08.004","article-title":"The minimum clinically important difference of the international consultation on incontinence questionnaires (ICIQ-UI SF and ICIQ-LUTSqol)","volume":"133","author":"Lim","year":"2019","journal-title":"Urology"},{"key":"10.1016\/j.maturitas.2025.108658_bb0110","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/aogs.14353","article-title":"The evidence behind the use of LASER for genitourinary syndrome of menopause, vulvovaginal atrophy, urinary incontinence and lichen sclerosus: a state-of-the-art review","volume":"101","author":"Mortensen","year":"2022","journal-title":"Acta Obstet. Gynecol. Scand."}],"container-title":["Maturitas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512225004669?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378512225004669?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T14:45:59Z","timestamp":1754318759000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378512225004669"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":22,"alternative-id":["S0378512225004669"],"URL":"https:\/\/doi.org\/10.1016\/j.maturitas.2025.108658","relation":{},"ISSN":["0378-5122"],"issn-type":[{"value":"0378-5122","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vaginal CO2 laser treatment for urinary stress incontinence: A randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Maturitas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.maturitas.2025.108658","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"108658"}}